- Ilopango, Departamento de San Salvador, El Salvador
Research Interests:
Pancreatic incidentalomas are defined as asymptomatic pancreatic lesions, discovered incidentally by imaging for an unrelated indication. They are being discovered with increasing frequency as the use of high quality cross sectional... more
Pancreatic incidentalomas are defined as asymptomatic pancreatic lesions, discovered incidentally by imaging for an unrelated indication. They are being discovered with increasing frequency as the use of high quality cross sectional imaging is becoming more widespread. These lesions cover a wide spectrum of pathology from benign simple cysts through potentially malignant lesions such as intraductal papillary mucinous neoplasia, to frankly malignant adenocarcinoma. In this article we outline the incidence, imaging characteristics and natural history of the various incidental lesions with emphasis to neuroendocrine tumors. A diagnostic approach is also suggested, including the rational use of further imaging, serum biochemistry and the utility of ultrasound guided aspiration of cyst fluid if present. We examine several proposed classification systems and discuss the role of surgery, surveillance and prognosis.
Research Interests:
Research Interests:
Pheochromocytomas may produce several vasoactive peptides. We studied a 39-year-old man who presented with paroxysmal flushing and abdominal pain with normal blood pressure. Laboratory and radiologic studies established the diagnosis of... more
Pheochromocytomas may produce several vasoactive peptides. We studied a 39-year-old man who presented with paroxysmal flushing and abdominal pain with normal blood pressure. Laboratory and radiologic studies established the diagnosis of right adrenal pheochromocytoma, and histologic and ultrastructural examination showed the tumor to be a typical pheochromocytoma. Tissue culture yielded large quantities of norepinephrine and epinephrine. However, immunohistochemical studies, tissue assays, and in vitro cultures documented production of several peptides, including calcitonin gene-related peptide and vasoactive intestinal polypeptide in tumor cells. The patient has been asymptomatic after tumor resection. Production of multiple peptides by this tumor may account for the flushing and lack of hypertension, despite elevated catecholamine levels in this patient.
Research Interests:
Thromboxane B2 (TxB2) the stable metabolite of thromboxane A2 may be released as a response to ischemia. With the aim of investigating its role as an early diagnostic test in mesenteric thrombosis, immunoreactive TxB2 was measured in... more
Thromboxane B2 (TxB2) the stable metabolite of thromboxane A2 may be released as a response to ischemia. With the aim of investigating its role as an early diagnostic test in mesenteric thrombosis, immunoreactive TxB2 was measured in urine aliquotes in six sham operated dogs, nine dogs subjected to superior mesenteric artery ligation, and twelve dogs with superior mesenteric vein ligation. One hour urine volumes were collected before surgery and during the eight hours after the experimental procedures, and urinary osmolarities were also determined in each sample. Basal TxB2 levels were comparable in all groups. Although all groups showed a significant and rapid (one hour) increase in TxB2 as a response to surgery, in the controls it returned to normal after six hours, whereas in the rest a continuously increased production persisted throughout the study period. There was no difference in t-test comparisons depending on the sort of thrombosis. In spite of the urinary dilution induced...
Research Interests:
To explain the decreased success of cryopreserved versus fresh parathyroid autotransplants, we investigated the effect of cryopreservation on parathyroid function. Parathyroid cryopreserved tissue from surgical specimens of 18 patients... more
To explain the decreased success of cryopreserved versus fresh parathyroid autotransplants, we investigated the effect of cryopreservation on parathyroid function. Parathyroid cryopreserved tissue from surgical specimens of 18 patients was analyzed in a comparative fashion with 10 fresh abnormal glands. Cell viability was evaluated by a double-fluorescence technique, and parathyroid hormone secretion was detected from individually dispersed parathyroid cells with the reverse hemolytic plaque assay. The plaque area reflected the amount of parathyroid hormone secreted by each cell, and the percentage of plaque-forming cells represented the number of secreting cells. Feedback regulatory mechanisms remained intact for both fresh and cryopreserved tissue as shown over a wide range of calcium concentrations. The percentage of viable cells from fresh and cryopreserved tissue was always in excess of 88%. No significant difference was noted in the percentage of plaque-forming cells nor the a...
Research Interests:
Research Interests:
Research Interests:
To determine the prognostic value of the soft-tissue biopsy to handle contaminated or infected surgical wounds with delayed primary closure. Comparative, prolective, blind and observational. Referral tertiary care center. We included 70... more
To determine the prognostic value of the soft-tissue biopsy to handle contaminated or infected surgical wounds with delayed primary closure. Comparative, prolective, blind and observational. Referral tertiary care center. We included 70 patients distributed in two groups: Group I: 50 patients who underwent contaminated or infected abdominal surgery; and Group II: 20 patients who underwent clean or clean contaminated abdominal surgery and developed surgical wound abscess. Daily cleaning and water irrigation and periodic debridement were done in all the cases; after five days (excluding infection), two tissue biopsies for quantitative culture and wound closure were performed. In Group I, nine of 26 patients (35%) with positive culture (greater than 10(5) colony forming units/g) developed infection and none of 24 with negative culture (p less than 0.01, Fisher); the negative predictive value (nPV) was 100% and the positive predictive value (pPV) was 35%. In Group II, seven of 12 patien...
With the aim of developing guidelines for investigation and management of adrenal incidentalomas, 2066 patients with adrenal masses were analyzed from a total of 61,054 computerized tomographic (CT) scans done from 1985 through 1989.... more
With the aim of developing guidelines for investigation and management of adrenal incidentalomas, 2066 patients with adrenal masses were analyzed from a total of 61,054 computerized tomographic (CT) scans done from 1985 through 1989. Excluding patients with previous or concurrent malignancies, adrenal tumors localized after biochemical documentation of disease, and adrenal nodules less than 1 cm, 259 patients (0.4%) remained for analysis. Added to these were 83 patients (total 342) in whom the adrenal tumor had been found elsewhere before referral. There were 136 men and 206 women with a mean age of 62 years. Tumor diameter ranged from 1 to 11 cm (average 2.5 cm). Studies to evaluate biochemical hyperfunction were performed in 172 patients (50%), 2 of whom were found to have cortisol-producing tumors and 5 pheochromocytomas. Histologic proof of diagnosis was obtained in 55 patients at the time of adrenalectomy. Malignancy was discovered in five patients (four primary and one metasta...
Research Interests:
The aim of this retrospective study was to evaluate the impact of resident participation in the results of surgical treatment in 1149 consecutive patients operated for biliary disease between January, 1980 and December, 1987 at the... more
The aim of this retrospective study was to evaluate the impact of resident participation in the results of surgical treatment in 1149 consecutive patients operated for biliary disease between January, 1980 and December, 1987 at the Instituto Nacional de la Nutrición "Salvador Zubirán". Patients were divided in three groups: GROUP I. 640 cases treated by surgical residents under a senior surgeon supervision. GROUP II. 168 patients operated by the chief surgical resident. GROUP III. 341 patients treated by senior staff surgeons. Age, sex and risk factors were similar between groups. Residents performed more operative cholangiograms (p less than 0.05). In general, senior surgeons performed more transduodenal sphincteroplasties (p less than 0.05) and other additional procedures like appendectomies and gastrostomies during the same surgery. Wound infection was more frequent in group III patients (p less than 0.005) but there was no significant clinical difference in other posto...
Research Interests:
Research Interests: Humans, Female, Male, Risk factors, Aged, and 7 moreMiddle Aged, Adult, Risk Factors, Appendectomy, Cholecystectomy, Medical Records, and Hemorrhoids
Between January 1976 and December 1987, 44 patients with idiopathic thrombocytopenic purpura were submitted to splenectomy. This study analyzes the results of treatment and the usefulness of several prognostic markers. There were 38... more
Between January 1976 and December 1987, 44 patients with idiopathic thrombocytopenic purpura were submitted to splenectomy. This study analyzes the results of treatment and the usefulness of several prognostic markers. There were 38 female patients and six males with a median age of 28.5 years (range 11 to 66 years). Forty two out of 44 patients received preoperative steroids. Seventy five percent achieved a satisfactory response to this treatment but 31 relapsed (in eight recurrence was observed when the steroid dose was tapered). Eleven patients persisted symptomatic notwithstanding medical treatment. In two cases splenectomy was performed as an emergency procedure, and in one patient who was already in remission with previous steroid treatment, splenectomy was performed for other medical reasons. Operative mortality rate was 4 percent, and five patients developed postoperative complications (three had pneumonia, one pulmonary thromboembolism and one would infection). Eighty four ...
Research Interests:
Research Interests:
Although rare following initial cervical exploration, reoperative parathyroid surgery may cause permanent hypoparathyroidism in 15% to 30% of patients. Immediate fresh or delayed cryopreserved parathyroid autotransplantation is the... more
Although rare following initial cervical exploration, reoperative parathyroid surgery may cause permanent hypoparathyroidism in 15% to 30% of patients. Immediate fresh or delayed cryopreserved parathyroid autotransplantation is the principal surgical option to resolve this complication. Between 1980 and 1990, 18 and 12 patients underwent immediate and cryopreserved autotransplantation, respectively. With a mean follow-up of nearly 5 years, 61% of the immediate and 42% of the cryopreserved tissue showed evidence of function. However, only 10 (55%) and two (17%) of the respective patients had completely discontinued treatment with calcium supplementation. Graft-dependent hypercalcemia can occur with either technique. We conclude that until cryopreserved tissue can be transplanted with more reliable success and if the excised abnormal parathyroid likely represents the only remaining gland, we would advise immediate autotransplantation. In the reoperative setting, unless a residual norm...
Research Interests:
SUMMARY Eucalyptus nitens is an important commercial fast growing species planted mainly in Chile and Australia (Tasmania). In Chile there are not previously published studies quantifying leaf area in adult forest plantations of E.... more
SUMMARY Eucalyptus nitens is an important commercial fast growing species planted mainly in Chile and Australia (Tasmania). In Chile there are not previously published studies quantifying leaf area in adult forest plantations of E. nitens. This study presents the effect ...
Research Interests:
Obesity is a condition that has been associated with gastroesophageal reflux disease (GERD), however, a cause-effect relationship has not been established. To analyze current evidence evaluating the relationship between obesity and GERD,... more
Obesity is a condition that has been associated with gastroesophageal reflux disease (GERD), however, a cause-effect relationship has not been established. To analyze current evidence evaluating the relationship between obesity and GERD, as well as the impact of hypocaloric diets and bariatric surgery in gastroesophageal reflux symptoms. An electronic search in the MEDLINE was performed, looking for information published during the past 15 years: Cohort studies, case-control studies, case series and case reports, including the following key words: "heartburn", "reflux", "gerd", "reflux esophagitis", "obesity", "overweight", "diet", "bariatric surgery" were analized. Thirty-one articles were included. These studies were classified according to the diagnostic method of GERD (i.e., manometry, 24-hour pH monitoring, esophageal transit, endoscopy) and type of bariatric surgery: Adjustable gastric banding (AGB...
Research Interests:
Chile has an important tree cover of Eucalyptus nitens (Deane and Maiden) plantations destined primarily for pulpwood production. Nevertheless, other products such as sawlogs and veneers are required because of the continually changing... more
Chile has an important tree cover of Eucalyptus nitens (Deane and Maiden) plantations destined primarily for pulpwood production. Nevertheless, other products such as sawlogs and veneers are required because of the continually changing market for wood, as well as the need to ...
Research Interests:
The nonalcoholic steatohepatitis (NASH) is a common disorder in obese, type 2 diabetics, female and patients with dislipidaemia. Hepatic biochemical test are abnormal. Despite the lack of its own morphological characteristics, NASH can... more
The nonalcoholic steatohepatitis (NASH) is a common disorder in obese, type 2 diabetics, female and patients with dislipidaemia. Hepatic biochemical test are abnormal. Despite the lack of its own morphological characteristics, NASH can be differentiated from other pathologies, the gold standard for diagnosis is liver biopsy. Material and methods: We designed a retrolective, comparative, observational and crosssectional study. Thirtyfive obese subjects (11 men and 24 women) who underwent to bariatric surgery and liver biopsy were included. Data were taken from clinical files, such as anthropometric and biochemical test. Those who had clinical history of related alcohol ingestión or liver damage related to drugs were excluded. A experimented pathologist classified the biopsies according to Brunt classification. Liver slides were classified according to 1) presence of NASH; 2) Inflammation and 3) Fibrosis. Differences between groups were analysed by ANOVA and Spearman correlation. ...
Proximal duodenal-ileal end-to-side bypass with sleeve gastrectomy is a new bariatric technique based on the biliopancreatic diversion with duodenal switch in which after the sleeve gastrectomy, the duodenum is anastomosed to the ileum in... more
Proximal duodenal-ileal end-to-side bypass with sleeve gastrectomy is a new bariatric technique based on the biliopancreatic diversion with duodenal switch in which after the sleeve gastrectomy, the duodenum is anastomosed to the ileum in a Billroth-II fashion. A 200-cm common channel-alimentary limb is devised. Anticipating an appropriate weight loss, at least similar to that obtained after gastric bypass, theoretical benefits for operated patients are a shorter operative time, the performance of only one anastomosis, and no mesentery opening. A prospective trial is now being conducted to find out the results of the procedure and to compare them to those obtained with gastric bypass and standard duodenal switch.
Research Interests:
ABSTRACT Alfalfa plants (Medicago sativa, L. cv. Aragón) inoculated with Rhizobium meliloti weregrown with a N-free-nutrient solution in controlled environmental chambers. After 5 weeks plants were placed under 2 irradiance regimes (120... more
ABSTRACT Alfalfa plants (Medicago sativa, L. cv. Aragón) inoculated with Rhizobium meliloti weregrown with a N-free-nutrient solution in controlled environmental chambers. After 5 weeks plants were placed under 2 irradiance regimes (120 and 60 μE · m-2 · s-1) and different N concentrations were supplied to treatment plants as Ca(NO3)2. Rates of acetylene-dependent ethylene production and CO2 uptake were determined 2 days later. The addition of 1.75 and 3.5 mM N03- to plants in each level of irradiance decreased both nitrogenase activity and CO2 assimilation regardless of the light intensity. The addition of 7 and 14 mM NO3- resulted in an enhanced leaf photosynthesis. Simultaneously, the C2H2 reduction rate by nodulated plants at 60 μE was lower than that of N2-dependent plants, while plants at 120 μE had similar acetylene reduction values. Higher levels of combined nitrogen, 28 and 56 mM NO3-, reduced nitrogenase activity of plants under both of the two light intensities and CO2 uptake by plants at 60 μE. However, current photosynthesis was not affected in plants at 120 μE. These results are interpreted as showing that alfalfa plants can utilize nitrate to improve CO2 assimilation without inhibiting N2 fixation when plants are under conditions in which light is not saturating.
Research Interests:
The non-alcoholic steato-hepatitis (NASH) is a common disorder in obese, type 2 diabetics, female and patients with dislipidaemia. Hepatic biochemical test are abnormal. Despite the lack of its own morphological characteristics, NASH can... more
The non-alcoholic steato-hepatitis (NASH) is a common disorder in obese, type 2 diabetics, female and patients with dislipidaemia. Hepatic biochemical test are abnormal. Despite the lack of its own morphological characteristics, NASH can be differentiated from other pathologies, the gold standard for diagnosis is liver biopsy. We designed a retrolective, comparative, observational and cross-sectional study. Thirty-five obese subjects (11 men and 24 women) who underwent to bariatric surgery and liuer biopsy were included. Data were taken from clinical files, such as anthropometric and biochemical test. Those who had clinical history of related alcohol ingestion or liver damage related to drugs were excluded. A experimented pathologist classified the biopsies according to Brunt classification. Liver slides were classified according to 1) presence of NASH; 2) Inflammation and 3) Fibrosis. Differences between groups were analysed by ANOVA and Spearman correlation. We found differences b...
Research Interests: Bariatric Surgery, Biopsy, Insulin Resistance, Humans, Liver Cirrhosis, and 15 moreFatty acids, Female, Male, Hepatitis, Body Mass Index, Prevalence, Middle Aged, Fatty Liver, Adult, Retrospective Studies, Body Height, Cross Sectional Studies, Aspartate Aminotransferases, Liver function tests, and Alanine Transaminase
Research Interests:
Research Interests:
Research Interests: Air Quality, Remote Sensing, Human Factors, Wildland Fire, Multidisciplinary, and 12 moreEcological Modelling, Forest fire, Logistic Regression, Web Map Service, Ecological, Soil Degradation, Fire Risk, Spatial resolution, Indexation, Fuel Management, Geographic Information System, and Burn Severity
We have recently validated a reverse hemolytic plaque assay (RHPA) for the quantitative measurement of parathyroid hormone release from single isolated parathyroid cells. The information regarding secretory behavior of normal and abnormal... more
We have recently validated a reverse hemolytic plaque assay (RHPA) for the quantitative measurement of parathyroid hormone release from single isolated parathyroid cells. The information regarding secretory behavior of normal and abnormal parathyroid tissue has been based previously on fluorescent spectroscopy or quantification of immunoreactive parathyroid hormone by radioimmunoassay. Thus, individual differences in secretion and assessment of viability are not clearly measured in these types of experiments. The RHPA has the advantage of allowing measurements of secretory activity in individual viable parathyroid cells. In this report, we have modified the RHPA to measure the release of parathyroid hormone from human cells. This is the first instance of measurement of hormone secretion from human cells, and we present data indicating the specificity of the assay for human parathyroid hormone. The response of normal human parathyroid cells to alterations in extracellular calcium was...
Research Interests: Surgery, Calcium, Humans, Sheep, Animals, and 4 moreParathyroid Hormone, Clinical Sciences, Cattle, and Erythrocytes
Temperate forests of Chile exhibit high biodiversity, which generates a wide range of habitats for wildlife. These valuable natural ecosystems have been affected by major natural and anthropogenic processes that have reduced habitats,... more
Temperate forests of Chile exhibit high biodiversity, which generates a wide range of habitats for wildlife. These valuable natural ecosystems have been affected by major natural and anthropogenic processes that have reduced habitats, resulting in serious ecological problems, given both the high endemism of certain avian groups in these forests and the complexity of their habitat selection. Continued degradation and
Research Interests: Ecological Informatics, Wildlife Conservation, Biological Sciences, Forest Planning, Forest Management, and 9 moreHabitat Selection, Indicator species, Environmental Variables, Prediction Model, Decision making process, Geographic Information System, Wildlife Habitat, Maximum entropy, and Temperate Forest
Research Interests:
Research Interests: Bariatric Surgery, Quality of life, Treatment Outcome, Adolescent, Prospective studies, and 28 moreHumans, Weight Loss, Taiwan, Female, Male, Young Adult, Body Mass Index, Length of Stay, Obesity Surgery, Clinical Sciences, Aged, Middle Aged, Adult, Public health systems and services research, Time Factors, Retrospective Studies, Weight Reduction, Morbid Obesity, Reproducibility of Results, Postoperative Complication, Body Weight, Clinical Competence, Gastric Bypass, Stomach, Laparoscopy, Mortality rate, Cohort Studies, and Conservative treatment
Research Interests: Treatment Outcome, Risk assessment, Probability, Prospective studies, Humans, and 25 moreObstructive sleep apnea, Weight Loss, Female, Male, Follow-up studies, Body Mass Index, Obesity Surgery, Clinical Sciences, Middle Aged, Adult, Vital Capacity, Forced Vital Capacity, Public health systems and services research, Time Factors, Weight Reduction, Morbid Obesity, Risk Assessment, Pulmonary Function, Normal Distribution, Hypoventilation, Laparoscopy, Pulmonary disease, Respiratory Function, Pulmonary Gas Exchange, and Tidal volume
Research Interests: Bariatric Surgery, Skeletal muscle biology, Acute kidney injury, Laparoscopic Surgery, Humans, and 14 moreFemale, Renal failure, Risk factors, Creatine Kinase, Obesity Surgery, Clinical Sciences, Pressure, Adult, Public health systems and services research, Necrosis, Morbid Obesity, Risk Factors, Gastric Bypass, and Rhabdomyolysis
Research Interests:
Research Interests: Bariatric Surgery, Physical Activity, Treatment Outcome, Humans, Weight Loss, and 15 moreFemale, Male, Obesity Surgery, Clinical Sciences, Middle Aged, Spirometry, Adult, Public health systems and services research, Morbid Obesity, Postoperative Complication, Body Weight, Randomized Clinical Trial, Laparoscopy, Respiratory Function, and Postoperative Period
Research Interests:
Oncocytic change involves a cytoplasmic enlargement due to mitochondrial accumulation observed in a wide variety of conditions and in multiple organs. It can be reactive or neoplastic. In the thyroid gland, this change is a metaplastic... more
Oncocytic change involves a cytoplasmic enlargement due to mitochondrial accumulation observed in a wide variety of conditions and in multiple organs. It can be reactive or neoplastic. In the thyroid gland, this change is a metaplastic phenomenon that takes place under different circumstances that promote cellular stress, and could even produce a true neoplasm, both benign or malignant. The oncocytic adenoma, a malignant tumor will be described. We analyzed four cases studied at the surgical pathology department of the American British Cowdray Medical Center in Mexico City that displayed unusual cytomorphological features. They became a diagnostic challenge and in order to solve it we reviewed their morphological spectrum. Tumor characteristics in all cases included: massive ischemic necrosis short after a fine needle aspiration biopsy was performed, unexpected large size, coexistence with a malignant independent neoplasm and cytological features similar to those observed in papilla...
Research Interests:
Laparoscopic resection of islet cell tumors has been performed in some selected cases. The aim of the study was to analyze the experience of two institutions in the laparoscopic management of insulinomas. In a 4-year period,... more
Laparoscopic resection of islet cell tumors has been performed in some selected cases. The aim of the study was to analyze the experience of two institutions in the laparoscopic management of insulinomas. In a 4-year period, videolaparoscopic resection of sporadic insulinomas was performed in 9 patients. All patients had hypoglycemia/hyperinsulinism and a solitary tumor demonstrated by image studies. Demographics, surgical findings, results, and complications were analyzed. Mean age of the patients was 43 years. One patient was male and eight were females. One tumor was located in the head of the pancreas, 4 in the body, and 4 in the tail. Laparoscopic resection was completed in all patients. Procedures included 4 enucleations and 5 distal pancreatectomies. Pancreatic resection with splenic preservation was achieved in 4 cases. Intraoperative ultrasound was used in 7 patients. Mean size of the tumors was 1.6 cm. All patients became normoglycemic after surgery. Complications included one pancreatic fistula, one pleural effusion, and one peripancreatic fluid collection. All resolved spontaneously. In a follow-up period between 3 and 48 months no evidence of recurrence has been observed. This series supports laparoscopic resection of preoperatively localized benign solitary insulinomas. The operation provides the advantages of minimally invasive surgery and can be safely performed in most cases.
Research Interests:
Research Interests:
In most centers only selected patients with high risk thyroid nodules undergo thyroid surgery, and fine needle aspiration biopsy (FNA) is used to select patients for surgical treatment. The aim of the present study was to evaluate the... more
In most centers only selected patients with high risk thyroid nodules undergo thyroid surgery, and fine needle aspiration biopsy (FNA) is used to select patients for surgical treatment. The aim of the present study was to evaluate the impact of FNA on the management of thyroid nodules at our institution. A total of 872 patients who underwent FNA over a period of 7 years were retrospectively analyzed. There were 66 men and 806 women with a mean age of 40 +/- 15 years. Altogether 549 patients presented with a thyroid nodule and 323 with multinodular disease. The sensitivity and specificity of FNA were 90.0% and 99.8%, respectively. The positive and negative predictive values were 98% and 99%, respectively, and the accuracy was 99%. Our results are in agreement with those of other reports establishing that FNA of the thyroid is safe, reliable, and effective for differentiating benign from malignant nodules.
Research Interests:
Research Interests:
Research Interests:
Research Interests:
Research Interests: Adolescent, Laparoscopic Surgery, Humans, Female, Male, and 7 moreClinical Sciences, Aged, Middle Aged, Adult, Drainage, Surgical, and Laparoscopy
Laparoscopic Roux-en-Y gastric bypass (LRYGB) leads to significant weight loss and correction of co-morbidities in most patients. Banded LRYGB was designed to enhance weight loss and avoid weight regain. A randomized controlled pilot... more
Laparoscopic Roux-en-Y gastric bypass (LRYGB) leads to significant weight loss and correction of co-morbidities in most patients. Banded LRYGB was designed to enhance weight loss and avoid weight regain. A randomized controlled pilot trial was designed to comparatively analyze the results and complications of banded (6.5 cm) and unbanded LRYGB. The present study was an interim analysis focused on morbidity, mortality, and maximal weight loss. The 60 patients were divided into 2 groups. Group 1 underwent unbanded LRYGB (n = 30) and group 2 underwent banded LRYGB (n = 30). No differences were found between the 2 groups in terms of age, gender, body mass index, or operative time. No significant differences were found in the percentage of excess weight loss and body mass index at 6, 12, and 24 months between the 2 groups. The frequency of complications was similar in both groups; 1 patient required band removal because of stenosis at the level of the mesh. The weight loss pattern in both groups was similar at 1 and 2 years postoperatively. Proper assessment of weight maintenance and late weight regain will require longer follow-up.
Research Interests:
Research Interests: Surgery, Treatment Outcome, Adolescent, Laparoscopic Surgery, Spleen, and 20 moreProspective studies, Humans, Hospital costs, Female, Male, Length of Stay, Clinical Sciences, Aged, Middle Aged, Adult, Time Factors, Retrospective Studies, Cost Saving, Blood Transfusion, Laparoscopy, Platelet Count, Cohort Studies, The American, Splenectomy, and Laparotomy
The sentinel lymph node has been used in several tumors. The aim of this study was to analyze the accuracy of the sentinel node in papillary thyroid carcinoma. A series of 22 patients with papillary thyroid carcinoma were included.... more
The sentinel lymph node has been used in several tumors. The aim of this study was to analyze the accuracy of the sentinel node in papillary thyroid carcinoma. A series of 22 patients with papillary thyroid carcinoma were included. Approximately 0.5 cc of isosulfan blue dye was injected at operation to trace the sentinel node. Lymph node dissection of the ipsilateral central compartment and extensive sampling of the jugular compartment were performed in addition to sentinel node resection. Surgical specimens were stained with hematoxylin-eosin, and negative sentinel nodes were subsequently stained with immunohistochemistry for cytokeratin-7. Mean age was 37 +/- 14 years. Twenty patients were women, and 2 were men. Mean tumor size was 2.5 +/- 1 cm. A sentinel lymph node was found in 20 patients. With use of hematoxylin-eosin, metastases were identified in 12/20 sentinel nodes (60%). Eleven patients with positive sentinel nodes presented additional lymph node metastases: 9 in the central compartment, 1 in the jugular compartment, and 1 in both compartments. Two patients with negative sentinel nodes had lymph node metastases elsewhere. When sentinel nodes were processed by immunohistochemistry, accuracy increased to 100%. Sentinel node is highly accurate for diagnosing metastases in papillary thyroid carcinoma.