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  • Bucharest, Bucuresti, Romania
Biodegradable metallic materials represent a new class of biocompatible materials for medical applications based on numerous advantages. Among them, those based on zinc have a rate of degradation close to the healing period required by... more
Biodegradable metallic materials represent a new class of biocompatible materials for medical applications based on numerous advantages. Among them, those based on zinc have a rate of degradation close to the healing period required by many clinical problems, which makes them more suitable than those based on magnesium or iron. The poor mechanical properties of Zn could be significantly improved by the addition of Mg and Y. In this research, we analyze the electro-chemical and mechanical behavior of a new alloy based on Zn3Mg0.7Y compared with pure Zn and Zn3Mg materials. Microstructure and chemical composition were investigated by electron microscopy and energy dispersive spectroscopy. The electrochemical corrosion was analyzed by linear polarization (LP), cyclic polarization (CP) and electrochemical impedance spectroscopy (EIS). For hardness and scratch resistance, a microhardness tester and a scratch module were used. Findings revealed that the mechanical properties of Zn improve...
In this longitudinal study we evaluated the risk factors for the effectiveness of orthodontic treatment in mixed dentition on a sample of 110 patients (52 boys and 58 girls) aged 6 to 10 years in northeastern Romania in the active phases... more
In this longitudinal study we evaluated the risk factors for the effectiveness of orthodontic treatment in mixed dentition on a sample of 110 patients (52 boys and 58 girls) aged 6 to 10 years in northeastern Romania in the active phases of orthodontic treatment. 13.6% of patients were quitted the treatment or did not come to scheduled appointments. Initially, removable functional appliances were used in 54.7% of patients and myofunctional activators in 45.3% of patients. After evaluating the 6-month treatment results (good in 64.7% patients and poor in 64.7% patients), the appliances were changed according to patient compliance and dental hygiene status. The treatment outcomes after 12 months were good in 78% of patients and decreased in 22% of patients. The effectiveness of orthodontic treatment in mixed dentition has depended both on parents' understanding of the need for treatment, but also on patient co-operation and compliance.
Supernumerary tooth represents a developmental anomaly that consists in duplication of tooth in the normal series. The presence of a supernumerary tooth may result in the appearance of aesthetic or functional problems in the... more
Supernumerary tooth represents a developmental anomaly that consists in duplication of tooth in the normal series. The presence of a supernumerary tooth may result in the appearance of aesthetic or functional problems in the dento-maxillary system. A girl, 11 years old, with upper midline shift following a supernumerary teeth and severe upper crowding was successfully treated after extraction of supernumerary tooth and four first bicuspids. Stages of diagnosis and treatment have been described in detail. In order to obtain good treatment results it was necessary to use an asymmetrical orthodontic mechanic. In this case report, the diagnostic workflow and current treatment concepts was presented and critically discussed.
Aim of the study was to investigate the Romanian population regarding the awareness of childhood language impairment. Material and methods: 75 Romanian volunteers (37 male and 38 female) aged 18-78 randomly selected were surveyed through... more
Aim of the study was to investigate the Romanian population regarding the awareness of childhood language impairment. Material and methods: 75 Romanian volunteers (37 male and 38 female) aged 18-78 randomly selected were surveyed through a questionnaire carried out by Working Group 3 of Cost Action IS1406, between March-May 2018. The questions were grouped in 5 sections: personal information, knowledge about childhood language impairment, management/ therapy/ intervention, the role of parents in intervention and improving the lives of these children. Multiple answers were analysed by the SPSS 16.0 package (SPSS Inc., Chicago, IL) for Windows. Results: 57.3% respondents knew the term childhood language impairment. 42.7% respondents heard about language therapy for children. 40% respondents believe that parents should engage in team work with the therapist. 77.3% of respondents believe that school education is the best ways to spread information about childhood language impairments. T...
Aim of the study was to identify the prevalence of patient anxiety before treatment and to determine patients' perception of the dental treatment risks. Material and methods. The cross-sectional study was conducted in 210 patients (69... more
Aim of the study was to identify the prevalence of patient anxiety before treatment and to determine patients' perception of the dental treatment risks. Material and methods. The cross-sectional study was conducted in 210 patients (69 males and 141 females) aged 11-70 years in northeastern Romania, who completed Corah's Dental Anxiety Scale, Revised (DAS-R), Modified Dental Anxiety Scale (MDAS) and Dental Concerns Assessment, Revised (DCA-R). Results. The overall scores of DAS-R indicated high anxiety in 4.3% of patients and severe anxiety or phobia in 2.9% of patients. Overall scores of the MDAS questionnaire indicated 5.2% of very anxious patients and 2.3% of highly anxious or phobic patients with dental treatments. DCA-R indicated high anxiety for injection and extraction. We found statistically significant differences between anxiety levels and age ranges as well as patients' environmental areas (p<0.05). Conclusions. Anxiety to dental practice can affect the qual...
Non extraction orthodontic treatment should be the best choice for both practitioners and patients when possible. That's why in the last decades people are concerned more and more in developing new techniques for solving orthodontic... more
Non extraction orthodontic treatment should be the best choice for both practitioners and patients when possible. That's why in the last decades people are concerned more and more in developing new techniques for solving orthodontic problems without dental extractions . In our paper we present an adolescent case with severe dental crowding with two stage orthodontic treatment; in the first stage we used pedex appliance for distal movement of upper molars and correction of transverse discrepancy, followed by the second stage with fixed orthodontic appliance. The patient presented ectopic upper canines and class II malocclusion. At the end of the treatment our patient presented correct dental alignment, functional and stable occlusion, good profile, nice smile and improvement of the facial esthetics.
Deep overbite treatment requires a correct diagnosis, an individualized treatment plan and effective treatment mechanics. The aim of the present study was to analyze the type and results of treatment in orthodontic patients with deep... more
Deep overbite treatment requires a correct diagnosis, an individualized treatment plan and effective treatment mechanics. The aim of the present study was to analyze the type and results of treatment in orthodontic patients with deep overbite. The orthodontic records of 1140 patients with malocclusions, aged between 6 and 38 years, were analyzed. The records of patients with deep overbite and 1-4 retroclined upper incisors (14.3% of patients) were selected and the type of treatment performed and its results were analyzed. Among the treated patients, 32.5% had mixed dentition and 67.5% permanent dentition. The orthodontic treatment of deep overbite was performed individually for each patient, staging the treatment in one or more stages of treatment. Removable appliances were used in 8.75% of patients, fixed appliances in 70.62% of patients and combinations of orthodontic appliances in 20.62% of patients. To correct the deep overbite, a mechanics of extrusion of the molars in 57.5% of patients, of intrusion of the incisors in 26.25% of patients and of upper incisors protruding in 16.25% of patients were used. The study showed that by establishing an individualized treatment and by applying an effective biomechanics to correct deep overbite, the proposed treatment objectives were achieved.
Our experiment focused on identifying the elemental chemical composition of salivary crystals' surface, obtained from patients with/without orthodontic appliances or metal-ceramic crowns in order to test their influence on human... more
Our experiment focused on identifying the elemental chemical composition of salivary crystals' surface, obtained from patients with/without orthodontic appliances or metal-ceramic crowns in order to test their influence on human saliva. We used 110 samples of saliva derived from 19 patients (11 males and 8 females), with ages between 11–26 years old, divided into three groups: the control sample (without orthodontic appliances/metal-ceramic crowns), the study sample A (with orthodontic appliances/physiognomic metal-ceramic crowns) and the study sample B (former patients with previous orthodontic appliances). The surface elemental chemical composition was observed through Scanning Electron Microscopy (SEM) and was analyzed by X-ray Energy Dispersive Spectroscopy (EDS). The statistical analysis was performed in SPSS 20.0. Metallic elements (Ni, Al, Zn) that do not derive from the chemical composition of human saliva were found on all the salivary crystals. There were found statist...
In dentistry treatment of difficult cases may be accomplished using an interdisciplinary approach. This article describes the orthodontic treatment in a female patient (12-years old) which was diagnosed with congenitally missing of upper... more
In dentistry treatment of difficult cases may be accomplished using an interdisciplinary approach. This article describes the orthodontic treatment in a female patient (12-years old) which was diagnosed with congenitally missing of upper left lateral incisor and Angle’s Class III malocclusion. The treatment plan was interdisciplinary using preprosthetic orthodontic treatment for facilitate the surgical, implant and restorative treatment. The treatment were favorable, fulfilled the patient expectation and improving facial esthetics and restoring the functions. This case demonstrates that an interdisciplinary team (orthodontist, dental surgeon, prosthodontist) is required for the successful treatment of the congenitally missing of lateral incisor to create ideal conditions for the insertion of the dental implant.
Aim: This study evaluates the influence of premature unilateral loss of mandibular deciduous molars on condylar and ramus vertical symmetry, on digital orthopantograms of a sample of Romanian patients. Material and methods: The... more
Aim: This study evaluates the influence of premature unilateral loss of mandibular deciduous molars on condylar and ramus vertical symmetry, on digital orthopantograms of a sample of Romanian patients. Material and methods: The retrospective study was performed on 200 patients (128 boys and 72 girls), between 6-9 years old, during 2010-2015, in the Clinic of Pediatric Dentistry Ambulatory of the “Sf. Spiridon” County Clinical Emergency Hospital from Iasi, Romania. The digitally measurements were made with Planmeca Romexis Viewer 3.0.1®, according method to a known method. Results: Statistically significant differences were found between the control group (without loss of deciduous molars) and the study group (with premature unilateral loss of mandibular deciduous molars) for mean values of the condylar asymmetry index (p=0.000), which were over 5-7%, indicating the condylar asymmetry. Conclusions: The premature unilateral loss of the mandibular deciduous molars is a risk factor for ...
Zinc biodegradable alloys attracted an increased interest in the last few years in the medical field among Mg and Fe-based materials. Knowing that the Mg element has a strengthening influence on Zn alloys, we analyze the effect of the... more
Zinc biodegradable alloys attracted an increased interest in the last few years in the medical field among Mg and Fe-based materials. Knowing that the Mg element has a strengthening influence on Zn alloys, we analyze the effect of the third element, namely, Y with expected results in mechanical properties improvement. Ternary ZnMgY samples were obtained through induction melting in Argon atmosphere from high purity (Zn, Mg, and Y) materials and MgY (70/30 wt%) master alloys with different percentages of Y and keeping the same percentage of Mg (3 wt%). The corrosion resistance and microhardness of ZnMgY alloys were compared with those of pure Zn and ZnMg binary alloy. Materials were characterized using scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), X-ray diffraction (XRD), linear and cyclic potentiometry, and immersion tests. All samples present generalized corrosion after immersion and electro-corrosion experiments in Dulbecco solution. The experimental re...
An alloy surface with possible applications in the medical field, Ti4A14Zr, was improved through the deposition of a thin hydroxyapatite (HA) layer. In this paper, we analyzed the growth of a HA layer through electrophoresis and the... more
An alloy surface with possible applications in the medical field, Ti4A14Zr, was improved through the deposition of a thin hydroxyapatite (HA) layer. In this paper, we analyzed the growth of a HA layer through electrophoresis and the corrosion resistance of the metallic sample covered with the ceramic layer. The substrate surface was processed via chemical procedures before the HA deposition. The state of the metallic surface and that of the layer of HA were investigated using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) analysis of the chemical composition. The results indicate a high increase in the corrosion resistance associated with the ceramic layer compared to the metallic basic layer. Moreover, the analysis revealed the formation of a homogeneous TiO2 layer on the surface of the metallic substrate. The titanium oxide layer identified by SEM–EDS and confirmed by EIS was very homogeneous and resistant, with a compact microstructural appearance and...
The surface condition of the materials involved in dentistry is significant for the subsequent operations that are applied in oral cavity. Samples of Co–Cr–W alloy, obtained through selective laser melting (SLM) 3D printing, with... more
The surface condition of the materials involved in dentistry is significant for the subsequent operations that are applied in oral cavity. Samples of Co–Cr–W alloy, obtained through selective laser melting (SLM) 3D printing, with different surface states were analyzed. Surface analysis after the 3D printing process and sandblasting was realized from microstructural, chemical composition, profilometry, droplet adhesion, scratch test, and microhardness perspectives. The results presented a hardening process and a roughness modification following the sandblasting procedure, a better adhesion of the liquid droplets, the appearance of micro-cracks during the scratch test, and the oxidation of the sample after the 3D printing process and surface processing.
Over the past decade, exploitation of antimicrobial effect of nanoparticles on viruses, fungi and bacteria, respectively have developed markedly. A close attention was received by the possibility of nanoparticles type drug delivery... more
Over the past decade, exploitation of antimicrobial effect of nanoparticles on viruses, fungi and bacteria, respectively have developed markedly. A close attention was received by the possibility of nanoparticles type drug delivery systems to limit the biofilm formation within the oral cavity due to their important properties such as delivery abilities, anti-adhesive and biocidal features. The major objective of this work was to obtain doxycycline-loaded chitosan nanoparticles and to analyze the properties of as prepared samples in order to prolong the antibiotic release. The synthesized nanoparticles had less than 100 nm using the classis or improved drug encapsulation technique in chitosan matrix. The study focused on the antimicrobial characteristic of nanoparticles for controlling oral infections.
The study aimed to determine the prevalence of dental midline deviation in an orthodontic group of patients.The study was performed on 384 orthodontic patients (164 boys and 220 girls), between 6-23 years old. The data collected from... more
The study aimed to determine the prevalence of dental midline deviation in an orthodontic group of patients.The study was performed on 384 orthodontic patients (164 boys and 220 girls), between 6-23 years old. The data collected from orthodontic records were analysed according to the gender, age stages, environments areas, type of dentition and Angle Classes of malocclusions. All analyses were carried out using the SPSS. In the studied group the prevalence of dental midline deviation was 20.70%. The prevalence of dental midline deviation was increased in girls (12.24%), in patients over 12 years old (8.35%), from urban areas (14.32%), with mixed dentition (11.45%) and with Class I (11.20%) and II division 1 (6.25%) malocclusions. We founded statistically significant high correlations between dental midline deviation and age stages (p=0.028), type of dentition (p=0.001) and Angle classes of malocclusions (p=0.006). The dental midline deviation, commonly encountered in orthodontic pra...
Metronidazole active molecules were intercalated in the inner space of MgAl layered double hydroxides by simple coprecipitation method. The new synthesized nanohybrid material and the pristine hydrotalcite were characterized by different... more
Metronidazole active molecules were intercalated in the inner space of MgAl layered double hydroxides by simple coprecipitation method. The new synthesized nanohybrid material and the pristine hydrotalcite were characterized by different techniques such as X-ray diffraction, infrared spectroscopy and UV-vis spectroscopy verifying thus the incorporation of the antibiotic into the lamellar gallery of hydrotalcite type anionic clay. Studies regarding metronidazole controlled release from synthetic nanocomposite showed that the organic-inorganic nanohybrid structure can serve as drug controlled release system for a wide variety of antibiotics and other molecules used in dental medicine in order to maintain good public health dentistry.
Amoxicillin and clavulanic acid are two of the most commonly prescribed antibacterial worldwide for treating oral infectious diseases. Oral health is of big importance for well-being and general health. A few novel drug delivery systems... more
Amoxicillin and clavulanic acid are two of the most commonly prescribed antibacterial worldwide for treating oral infectious diseases. Oral health is of big importance for well-being and general health. A few novel drug delivery systems were designed for oral treatment and prophylaxis of different diseases in the oral cavity. This work focused on the latest drug delivery development of the most common oral pathologies, namely, periodontitis, oral mucosal infections, dental caries and oral cancer. Herein we reveal the synthesis, characterization and application of chitosan nanoparticles for intracellular transport of the weakly cell-penetrating amoxicillin and clavulanic acid in order to improve their efficacy on bacterial infections.
In last few years, researchers focused on improvement of lifespan of dental mini-implants by coating them with nanopoarticles for a better osseo-integration, which also possesses antibacterial properties. Once their surface is coated with... more
In last few years, researchers focused on improvement of lifespan of dental mini-implants by coating them with nanopoarticles for a better osseo-integration, which also possesses antibacterial properties. Once their surface is coated with nanoparticles type silver dopped hydroxyapatite makes them durable and safe by a good integration into tissue and by preventing bacterial infections. It is well known that a particular problem with medical devices such as dental mini-implants is bacterial colonization. For this reason the use of nanoparticles coated mini-implants is a measure to prevent or to treat infections caused by microbial agents present in oral cavity. Our study considers the possibility of using silver doped hydroxyapatite thin films on titanium mini-implants as an osseo-integration and antibacterial component. Therefore several physic-chemical analyses were performed in order to determine their properties and to open new perspectives to develop nanoparticulated thin films ...
An important aspect of orthodontic microimplants is represented by biocompatibility and avoidance of infection development at living tissue surrounding it. Therefore, nanotechnology has the ability to improve this issue by coating... more
An important aspect of orthodontic microimplants is represented by biocompatibility and avoidance of infection development at living tissue surrounding it. Therefore, nanotechnology has the ability to improve this issue by coating microimplants with metal oxides type nanomaterials possessing antimicrobial effect. Some features of advanced nanostructured materials used as implant coatings, such as composition, structure, specific surface area, porosity, shape and size are factors that make them suitable as antimicrobial agents. The present work deals with the structural and morphological studies of ZnO and TiO2 nanoparticles used to combat oral diseases. Coating microimplants with nanosized titanium oxide (TiO2) and zinc oxide (ZnO) may improve conditions for osseointegration in accordance with preventing oral infection. These metal oxides nanopowders were synthesized using sol-gel method. Structural and morphological investigation were carried out by XRD and FTIR spectra, SEM-EDX an...
Anionic clay matrix acting as drug controlled release system have shown in last years a great potential for delivery of bioactive molecules and chemical therapeutics. This organic-inorganic nanohybrid system is high efficient offering an... more
Anionic clay matrix acting as drug controlled release system have shown in last years a great potential for delivery of bioactive molecules and chemical therapeutics. This organic-inorganic nanohybrid system is high efficient offering an excellent protection of intercalated compounds from degradation. Compared to other nanoparticles used in medical area, anionic clays type layered double hydroxides have found to be biocompatible according to toxicological studies. Ampicillin containing MgAlLDHs and ZnAlLDH samples have been prepared following two routes: anion-exchange procedure and reconstruction from calcined layered double hydroxides. Solid samples have been characterized by FTIR and SEM-EDX highlighting the alteration of pristine LDHs structure when the antibiotic is introduced in the interlayer gallery.
Nowadays, alongside metallic biomaterials, there is increasing interest in using degradable metals in an appreciable number of medical applications. There are new kinds of metallic biomaterials for medical applications and many new... more
Nowadays, alongside metallic biomaterials, there is increasing interest in using degradable metals in an appreciable number of medical applications. There are new kinds of metallic biomaterials for medical applications and many new findings have been reported over the past few years. Iron-based materials are a solution for biodegradable applications based on their mechanical and chemical properties. In order to control the corrosion rate of the Fe10Mn6Si alloy, we proposed the use of two additional elements, Ca and Mg, as corrosion promoters. The new material was obtained in an air-controlled atmosphere furnace after five melting operations. The material was in vitro analyzed from a corrosion resistance point of view. The experiments were realized by immersion (7, 14, and 30 days) in simulated body fluid (SBF) solution at 37 °C and a constant pH, and by electrochemical tests (electrochemical impedance spectroscopy (EIS), linear polarization (LP), cyclic polarization (CP)). Material ...
The study aimed to identify quantitative and relational characteristics of bone, dental and soft tissue structures for Class III malocclusion, according to gender and age range. 60 conventional lateral cephalograms were divided into two... more
The study aimed to identify quantitative and relational characteristics of bone, dental and soft tissue structures for Class III malocclusion, according to gender and age range. 60 conventional lateral cephalograms were divided into two groups according to ANB angle: the group of cases with skeletal Class III (n = 36) and a control group with skeletal Class I (n = 24). There were performed 53 digital cephalometric measurements according to Steiner, Tweed and Jarabak analyzes. The Kolmogorov-Smirnov, t-student and Levene tests were used to find the characteristics of Class III, using SPSS 16.0 for Windows. We found 14 parameters that distinguished the two classes disorders (the angles SNB, SND, FMA, IMPA, MeGoOcP, Mand 1-MeGo, NSAr, ArGoMe, NGoMe and SNPog; the distances Ao-Bo and lu-NPog; Holdaway and AFH ratios) and 3 parameters for the Class III age ranges (NGoAr angle, Ls-NsPog' distance and S-Ar:Ar-Go ratio) (p ≤ 0.05). There were found no significant differences between gen...
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Aim of the study. The aim of this study was to assess the third maxillary molar status, its eruption prognosis and to evaluate possible correlations between posterior available space and angulation. Material and methods. We examined... more
Aim of the study. The aim of this study was to assess the third maxillary molar status, its eruption prognosis and to evaluate possible correlations between posterior available space and angulation. Material and methods. We examined panoramic radiographs of 250 orthodontic patients, aged between 11 and 25 years, mean age 13,96 and we measured the mesiodistal diameter, the available posterior space distal to second molar and upper third molar angulation with the occlusal plane and with the adjacent tooth. Results. 75 (15%) third upper molars were congenitally missing; considering the available space we found a considerable increase in those patients with previous first molar extraction compared with the group without extractions; there is no or very weak correlation between posterior space and third molar angulation ( p>0,05), but strong inverse proportionally correlation between the angle formed by the long axis of the second and third molar and the angle of the third molar with ...
Impaction of a maxillary central incisor is a rare dental condition which is easy noticed by the patient and the general practitioners because it has a strong impact against dental and facial esthetics. In many cases this is due to the... more
Impaction of a maxillary central incisor is a rare dental condition which is easy noticed by the patient and the general practitioners because it has a strong impact against dental and facial esthetics. In many cases this is due to the presence of one or more supernumerary teeth, easy recognized on radiographs. The absolute indication in these situations is the early removal of the supernumerary teeth in order to minimalize the damage in the anterior area. Almost in all cases the surgical phase should be followed by the orthodontic phase in order to bring the impacted tooth in the dental alignment, to establish the proper occlusion and function. In our paper we present the case of a 9 years boy with left central maxillary incisor impaction and 2 supernumerary teeth in the anterior area. The case is presented step by step until the final result at the end of the treatment with the upper incisor in place
The purpose of orthodontic therapy with micro-implants was to strengthen the skeletal anchorage. Thus, in the specialty literature appeared numerous studies on the evolution of orthodontic micro-implants, technology and diversification of... more
The purpose of orthodontic therapy with micro-implants was to strengthen the skeletal anchorage. Thus, in the specialty literature appeared numerous studies on the evolution of orthodontic micro-implants, technology and diversification of clinical applications. The designs of micro-implants types used in orthodontics are presented, different methods of insertion, the steps of surgical procedures and various areas for placement of orthodontic micro-implants after clinical indications. It is presented an example of a clinical case requiring fixed orthodontic treatment using a micro-implant on the edentulous ridge for solving the problem of orthodontic anchorage.
To assess the reliability of two predictive parameters for third lower molar prognosis for eruption or impaction and to establish relationship between them. Materials and methods. We examined the ratio between third molar available... more
To assess the reliability of two predictive parameters for third lower molar prognosis for eruption or impaction and to establish relationship between them. Materials and methods. We examined the ratio between third molar available posterior space and the mesiodistal diameter of the mandibular third molar and the angulation of the long axis of the mandibular third molar with the long axis of the adjacent second molar measured on the orthopantomograms of 70 orthodontic patients before and after orthodontic treatment. The total number of molars taken into study was 130, 88 at patients who were treated without premolar extractions and 42 in patients treated by premolar extraction All the measurements were statistically analyzed for both groups and compared. Results. In the nonextraction group there was a slight increase in the posterior available space for those molars with favorable chances for eruption from the beginning, and also a positive change of angulation in the same condition...
Current orthodontic practice employs the use of a wide variety of devices that have acrylic components. Due to its chemical composition, there has long been a concern about its biocompatibility in the oral environment. Through this study... more
Current orthodontic practice employs the use of a wide variety of devices that have acrylic components. Due to its chemical composition, there has long been a concern about its biocompatibility in the oral environment. Through this study we aimed at determining the biocompatibility of the self-curing acrylate used in orthodontics. Our study was performed by analysing three study groups: the positive control group represented by copper amalgam fragments, the negative control group represented by human fibroblast cultures and the study group represented by self-curing acrylate fragments. The study groups were evaluated by means of microscopic analysis performed at three and six days with a Nikon Eclipse TE300 phase contrast microscope. Following the analysis at three days, a slight decrease in the concentration of fibroblasts around the material was noticed without revealing changes in shape. At six days an increase in cellular density similar to that of the control group was observed. Our study shows a good biocompatibility of in vitro self-polymerizing acrylate.
The risk factors analysis in medicine is a very complex problem, with significant practical implications in taking the right decisions in the health policies field. A useful approach is the study of interaction between risk factors... more
The risk factors analysis in medicine is a very complex problem, with significant practical implications in taking the right decisions in the health policies field. A useful approach is the study of interaction between risk factors through additive and multiplicative schemes, required when the identified risk factors are not independent in causing a certain outcome. Several models were developed to solve this problem, but it is critical to choose the right one, because different methods can lead to different conclusions about the same biological processes. Our paper describes the additive and multiplicative interaction schemes and presents a practical application of them in investigating the effects of a few particular diet habits on the chances to develop gingival recession, on a sample made from 2389 people coming from Iasi county. 8 diet habits were investigated; only 4 of them were identified as risk factors and, among the 6 possible paired combinations, 4 were identified as major positive interaction, 1 was identified as moderate interaction and 1 was identified as weak.
The purpose of this study was to evaluate on a group of 67 patients (29 boys and 38 girls) aged 6-37 years the frequency of the type of impacted teeth, the treatment performed, as well as to compare the images obtained on the panoramic... more
The purpose of this study was to evaluate on a group of 67 patients (29 boys and 38 girls) aged 6-37 years the frequency of the type of impacted teeth, the treatment performed, as well as to compare the images obtained on the panoramic radiographs and on the cone-beam computed tomography (CBCT) in order to establish an appropriate therapeutic decision. The impacted canine was the most frequent, followed by the incisor and premolar impaction. The most common therapeutic procedure was surgical exposure and orthodontic traction. The therapeutic decision was changed after examining the CBCT images, which brought additional information about the impacted tooth and the relationships with the adjacent tissues. The three-dimensional CBCT reconstructions were relevant for visualizing the path of the impacted tooth, the buccal-palatal choice of the surgical opening and the evolution of the orthodontic traction of the impacted tooth.
The aim of the study was to identify the significant necessity and predictive factors of dental crowding treatment, on 422 subjects (165 boys and 257 girls) from the North-East part of Romania. Correlations have been established between... more
The aim of the study was to identify the significant necessity and predictive factors of dental crowding treatment, on 422 subjects (165 boys and 257 girls) from the North-East part of Romania. Correlations have been established between dental crowding and age, dentition, Angle class of malocclusions, the etiological factors, types and modalities of treatments, and types of orthodontic appliances employed (p<0.05). Application of the chi-square test provided the necessity factors for the types of dental crowding treatments (p<0.001), while the Hosmer-Lemeshow test permitted to establish the predictive factors for the interceptive orthodontic treatment (maxillary expansion for mild and moderate crowdings), the corrective orthodontic treatment (maxillary expansion and orthodontic extraction for dental crowding with local causes) and also for the surgical-orthodontic treatment (orthodontic extraction for mild and moderate crowdings) (p>0.05). The necessity and predictive facto...
The media-enhanced teaching techniques became popular in the last years because they stimulate the students' engagement and motivation. The educational movies uploaded on YouTube became nowadays a highly used resource for learning in... more
The media-enhanced teaching techniques became popular in the last years because they stimulate the students' engagement and motivation. The educational movies uploaded on YouTube became nowadays a highly used resource for learning in the academic environment. We conducted an opinion survey among the students at the Faculty of Dental Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, Romania, about their agreement and interest in using educational movies as didactic tools, compared with the traditional teaching methods, and about the features they prefer in such materials. The study group included 170 students with average age 20.93 ± 2.751. Most students (91.2%) use didactic movies in their practical training; 77.6% think that the didactic movies from YouTube contain correct scientific information. 74.6% of the students like to learn using didactic movies, 39.7% of them appreciate the oral speech accompanied by PowerPoint Presentations and 46.6% like the oral speec...
Hamartomas are defined as an overgrowth of improper proportions of tissues indigenous to the anatomic area of occurrence. Hamartomas may occur in any organ of the body and are common in the spleen, liver, kidneys, lungs and pancreas.... more
Hamartomas are defined as an overgrowth of improper proportions of tissues indigenous to the anatomic area of occurrence. Hamartomas may occur in any organ of the body and are common in the spleen, liver, kidneys, lungs and pancreas. However, hamartomas of the tongue are extremely rare. The present article aims to present the progress of orthodontic treatment for open bite following tongue enlargement due to recurrent hamartoma in a healthy 7-year-old girl. Multidisciplinary periodontal, pedodontological, and then orthodontic treatment was planned. The patient received a myofunctional device to correct the position of the tongue and to control open frontal occlusion during the eruption of permanent teeth. After 6 months, the patient was reassessed and the maxilla expansion, occlusal status and tongue interposition were improved.
The hypodontia of a permanent tooth from a dental group represents a normal evolution in human dentition morphology. Nevertheless, the hypodontia of two teeth within a dental group is a rare developmental anomaly when not associated to a... more
The hypodontia of a permanent tooth from a dental group represents a normal evolution in human dentition morphology. Nevertheless, the hypodontia of two teeth within a dental group is a rare developmental anomaly when not associated to a systemic syndrome. The aim of this study was to report two rare cases of four maxillary premolars hypodontia, not including the third molar, of two white women from the same family. There were presented clinical, radiological and genetic findings. These cases are of interest to practitioners for four aspects: the atypical phenotype of hypodontia, the complexity of craniofacial morphological changes, the autosomal dominant familial inheritance with variable expressivity and the difficult classification of diagnosis.
was to determine the etiological risk factors and predictors of crossbite' treatment at children. 270 cases with crossbites and 255 controls with other malocclusions were uniformly evaluated. The crossbites cases were divided in group... more
was to determine the etiological risk factors and predictors of crossbite' treatment at children. 270 cases with crossbites and 255 controls with other malocclusions were uniformly evaluated. The crossbites cases were divided in group I (anterior crossbite), group II (posterior crossbite) and group III (anterior and posterior crossbites) and were compared between them per Angle Class malocclusions, dysfunctional and dental causes, associations with other discrepancies, as well by need and types of treatment. Binary logistic regression was used to find risk factors and predictors. The mean age of cases was 10.25?2.770 years. There were found significant differences between the groups of crossbites cases (p<0.05). There were identified risk factors (non-attrition of deciduous teeth, Angle Class II malocclusion and permanent teeth extraction) and protective factors of the crossbite (the tooth decay of deciduous teeth, eruption anomalies and tongue-thrust swallowing). There were ...
Establishing the prevalence of orofacial clefts in a community of institutionalized children and the correlations with sex, weight at birth, life environment, maternal age and children's associated diseases. The study was conducted on... more
Establishing the prevalence of orofacial clefts in a community of institutionalized children and the correlations with sex, weight at birth, life environment, maternal age and children's associated diseases. The study was conducted on a batch of 37 living newly-born (15 boys and 22 girls) from 1987 to 1997, with orofacial clefts, institutionalized in placement centers from Iasi, who survived and were treated medical and surgical. The data were collected from the records found in the archives of these centers and were statistically processed with the EpiInfo 3.4.3. software a Center for Disease Control and Prevention C.D.C. (U.S.A.). In 1987, children with orofacial clefts represented 7.42% and in 1997, 2.18% from the total of all children institutionalized. The average rate of prevalence of live births with orofacial clefts was 3.7/year. The frequency of clefts lip and palate in children who survived was 54.06%, clefts lip was 37.84% and clefts palate of 8.10%. Statistically sig...
ABSTRACT
Special materials are required in many applications to fulfill specific medical or industrial necessities. Biodegradable metallic materials present many attractive properties, especially mechanical ones correlated with good... more
Special materials are required in many applications to fulfill specific medical or industrial necessities. Biodegradable metallic materials present many attractive properties, especially mechanical ones correlated with good biocompatibility with vivant bodies. A biodegradable iron-based material was realized through electric arc-melting and induction furnace homogenization. The new chemical composition obtained presented a special property named SME (shape memory effect) based on the martensite transformation. Preliminary results about this special biodegradable material with a new chemical composition were realized for the chemical composition and structural and thermal characterization. Corrosion resistance was evaluated in Ringer’s solution through immersion tests for 1, 3, and 7 days, the solution pH was measured in time for 3 days with values for each minute, and electro-corrosion was measured using a potentiostat and a three electrode cell. The mass loss of the samples during ...

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