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... In "Flora Europaea" Vol. Liang XT, Roeder E (1984): Senecionine from Gynura segetum. Planta Med 51:362. Mattocks AR (1967): Detection of pyrrolizidine alkaloids on thin-layer chromatograms. J Chromatogr 27: 505-508. Melchior... more
... In "Flora Europaea" Vol. Liang XT, Roeder E (1984): Senecionine from Gynura segetum. Planta Med 51:362. Mattocks AR (1967): Detection of pyrrolizidine alkaloids on thin-layer chromatograms. J Chromatogr 27: 505-508. Melchior H (1964): Scrophulariaceae. ...
ABSTRACT
Following scientific risk assessments, several countries have imposed strict regulations on herbal medicines containing 1,2-dehydro-pyrrolizidine alkaloids. Using published data on the plants used in honey production, pyrrolizidine... more
Following scientific risk assessments, several countries have imposed strict regulations on herbal medicines containing 1,2-dehydro-pyrrolizidine alkaloids. Using published data on the plants used in honey production, pyrrolizidine alkaloid-containing plants are shown in this review to represent a significant source of honey worldwide. This observation, honey consumption data, reported levels of pyrrolizidine alkaloids in honeys, and consideration of tolerable exposure levels determined for pyrrolizidine alkaloids in herbal medicines, leads to the conclusion that some honey is a potential threat to health, especially for infants and fetuses, and further investigation is warranted.
... growth regulators. The roots excised from the seedlings and from plantlets are slow-ly growing in the liquid White and B-5 media (after obtaining sufficient quantity of biomass chemical stud-ies will be done later). Somatic seeds ...
A colour reaction for unsaturated pyrrolizidine alkaloids (PAs), which has already been published, is used for spectrophotometric determination of the toxic PAs in Symphyti Radix (Symphytum officinale L., Boraginaceae). By changing... more
A colour reaction for unsaturated pyrrolizidine alkaloids (PAs), which has already been published, is used for spectrophotometric determination of the toxic PAs in Symphyti Radix (Symphytum officinale L., Boraginaceae). By changing several parameters it was possible to reduce the detection limit to 1 microgram and to improve significantly the reproducibility of the quantitative determination. For Symphyti Radix a simple extraction method allowing the detection of 10 ppm PAs in 1 gram dried drug (0.001%) was validaded.