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wholepropolis.com
Propolis has been shown to exibit in vitro antimicrobial activity against periodontal pathogens. The aim of this study was to evaluate the efficacy of Brazilian Green Propolis Gel (BGPG) for the treatment of patients diagnosed with gingivitis and Chronic Periodontitis ...
Alternative Medicine
Propolis: Alternative Medicine for the Treatment of Oral Microbial Diseases2012 •
International Journal of Traditional and Complementary Medicine
A new release nanosystem mucoadhesive gel of Brazilian Red Propolis-containing chitosan: in vitro Citoxicity and Antimicrobial test. In vivo ligature induced periodontitis model- propolis treatment in rats2022 •
Red Propolis has been shown to be a potent antimicrobial, antinflammatory, antitumoral and antioxidant, however, is less studied against microorganisms and periodontal disease. This study aimed to investigate the antimicrobial, citoxicity properties and control of a induced periodontal pocket in rats of a red propolis mucoadhesive gel -containing chitosan. For this, we used two gels with concentrations of 5% (RPG5%) and 10% (RPG10%) of propolis and were compared with chitosan gel base 5% (CHG), propolis extract 5% (FRP5%) and chlorhexidine 0.12% (CHX0,12%). The products were tested against S. mutans, S. salivarius, S. sanguinis, L. casei, A. actinomycetemcomitans, E. faecalis, P. gingivalis, F. nucleatum, and C. albicans ATCC standards. The Minimum Inhibitory Concentration, Concentration Minimal Bactericidal and agar diffusion tests were performed according to CLSI standards. Ligature induced periodontitis model were used and the gel product were applied in test and control rats group. The results showed that all microorganisms were sensitive to the gel RPG5% and RPG10%. There was a reduction in insertion loss and alveolar resorption in the animals treated with propolis gel. Chitosan appears to have not affected the antimicrobial activity of propolis and there seems to have been a synergism between the products. On the other hand, new tests and clinical trials studies should be performed to confirm these parameters.
Revista Brasileira de Farmacognosia
Effect of Bulgarian propolis on the oral microflora in adolescents with plaque-induced gingivitis2018 •
Evidence-Based Complementary and Alternative Medicine
Influence of the Toothpaste with Brazilian Ethanol Extract Propolis on the Oral Cavity Health2013 •
Propolis-based therapeutic agents represent this potential for the development of new drugs in dental care. The aim of a clinical-cohort study was to determine the influence of application of toothpaste enriched with Brazilian extract of propolis (EEP) on health status of oral cavity. Laboratory analysis was conducted in order to assess the chemical composition of EEP including total phenolic compounds, the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity, ABTS radical cation scavenging activity, and FRAP assay. Clinical research involved two groups of subjects comprising 32 adult patients, with assessment based on the preliminary evaluation of the state of their marginal periodontium. The investigation of oral health indices API, OHI, and SBI and microbiological examination of oral microflora were also carried out. Results obtained indicated time-dependent microbial action of EEP at 50 mg/L concentration, with antimicrobial activity against Gram-positive bacteria. T...
The Saudi Dental Journal
Effect of honey in preventing gingivitis and dental caries in patients undergoing orthodontic treatment2014 •
Herbal medicine, also known as herbalism or botanical medicine, is a medical system based on the use of plants or plant extracts that may be eaten or applied to the skin. Since ancient times, herbal medicine has been used by many different cultures throughout the world to treat illness and to assist bodily functions. Herbal preparations can be derived from the root, leaves, seeds, and flowers. The preparations often contain a concoction of chemical substances may contain minerals and vitamins, and determining a specific active ingredient.Gingivitis is the mild form whereas periodontitis results in an irreversible loss of supporting structures of the teeth. Even though periodontal pathogens form a crucial component in the etiopathogenesis of periodontitis, there is a growing body of evidence suggesting oxidative stress playing a pivotal role in the disease initiation and progression. This review briefly describes the various herbs and organic substances which are easily available and can aid in quick relief from disease affecting the periodontium.
International Journal of Applied Pharmaceutics
EFFECTIVENESS OF TOOTHPASTE CONTAINING PROPOLIS, TEA TREE OIL, AND SODIUM MONOFLUOROPHOSPHATE AGAINST PLAQUE AND GINGIVITISObjective: Natural ingredients such as propolis and tea tree oil are known to possess antibacterial and anti-inflammatory effects that are effective against periodontal diseases. This study aimed to determine the effectiveness of toothpaste containing propolis, tea tree oil, and sodium monofluorophosphate against dental plaque and gingivitis. Methods: A randomized clinical trial was conducted for 7 days with 20 subjects in test (using the experimental toothpaste) and control (using toothpaste without any natural ingredients) groups each. Measurements of plaque index (PI) and papillary bleeding index (PBI) scores were performed on days 0 and 7. Results: Significant decreases (p<0.05) in PI (0.53-0.27) and PBI (0.55-0.11) scores were noted in the test group but not in the control group. Conclusions: Brushing teeth with toothpaste containing propolis, tea tree oil, and sodium monofluorophosphate might be effective in reducing the accumulation of dental plaque and the severity of gingival bleeding.
https://www.ijrrjournal.com/IJRR_Vol.8_Issue.12_Dec2021/IJRR-Abstract038.html
Propolis and Its Implications in Dentistry: A ReviewPropolis is a resinous substance obtained from the beehives that has antioxidant, anti-bacterial, anti-viral, antifungal, and anti-inflammatory activity. Its diverse chemical content is responsible for many valuable properties. Multiple applications of propolis have been studied and described in detail for centuries. Propolis has been used for surgical wound healing, caries prevention, treatment of dentin hypersensitivity, treatment of aphthous ulcers and propolis as a storage medium for avulsed teeth, root canal irrigating solution, and mouthwash. This paper aims to indicate the uses of Propolis in various fields of dentistry.
Odovtos - International Journal of Dental Sciences
Use and Effectiveness of Propolis on Chronic Periodontitis: a Systematic ReviewThe aim of this study was to determine the effect of propolis on non-surgical periodontal therapy in patients with chronic periodontitis (CP) as it appears in the recent literature. Propolis is a natural and biocompatible resinous substance that has shown, by means of several scientific studies, to possess medicinal properties such as antimicrobial, healing, anesthetic, anti-inflammatory, and analgesic, among others. There are several studies that have reported the use of propolis as a non-surgical treatment of CP, its comparison with other antimicrobials, and the improvement of clinical and microbiological parameters with scaling and root planing (SRP). A bibliographic search was conducted in the PubMed, Google Scholar, Web of Science, and Science Direct databases up to 2021. The results showed that there are very few reports focused on clinical studies; however, according to the analyzed data, propolis could be a good adjuvant for the treatment of patients with chronic periodontit...
In recent times, the use of natural products has gained momentum, either as a treatment or as adjuvants for other drugs in the treatment of different conditions. Propolis is a natural substance produced by bees which has proven useful for treating periodontal disease. This systematic review and meta-analysis gather evidence of the effectiveness of propolis in this kind of condition. The MEDLINE, CENTRAL, PubMed, EMBASE and Web of Science databases were searched for scientific articles to identify the findings published up to October 2020. The MeSH phrases used in the search were: “periodontal diseases AND propolis treatment”; “gingivitis AND propolis treatment”; “periodontitis AND propolis treatment”; “propolis treatment AND oral health”; “propolis AND oxidative stress AND periodontitis”. The Boolean operator “AND” was used to combine the searches. Randomized trials where propolis was used in the treatment of different periodontal conditions were included. Non-randomized clinical st...
Antioxidants
Apitherapy and Periodontal Disease: Insights into In Vitro, In Vivo, and Clinical Studies2022 •
2015 •
Applied Sciences
Study of the Antimicrobial Effect of an Ethanolic Extract of Propolis in Periodontal Disease2021 •
Emerging Trends in Oral Health Sciences and Dentistry
Herbal Dentifrices for Children2015 •
Natural Oral Care in Dental Therapy
Natural Oral Care in Dental Therapy2020 •
Evidence-Based Complementary and Alternative Medicine
The Biological Activity of Propolis-Containing Toothpaste on Oral Health Environment in Patients Who Underwent Implant-Supported Prosthodontic Rehabilitation2013 •
International Journal of Medicine and Pharmacy
Propolis 10%-Gel as a Topical Drug Candidate on Gingivitis2017 •
Periodontitis - A Useful Reference
Impact of Dental Plaque Biofilms in Periodontal Disease: Management and Future Therapy2017 •
Journal of Contemporary Dentistry
Use of Apitherapy as a Novel Practice in the Management of Oral Diseases: A Review of Literature2013 •
Antioxidants
Beneficial Role of Antioxidant Secondary Metabolites from Medicinal Plants in Maintaining Oral Health2021 •
Journal of Clinical and Experimental Dentistry
Effect of Propolis mouthwash on plaque and gingival indices over fixed orthodontic patientsEuropean Journal of Medicinal Plants
Phytotherapy in Dentistry: A Literature Review Based on Clinical DataRevista Brasileira de Farmacognosia
Hyptis pectinata gel prevents alveolar bone resorption in experimental periodontitis in ratsJournal of Clinical and Experimental Dentistry
Comparative analysis of the remineralization potential of CPP–ACP with Fluoride, Tri-Calcium Phosphate and Nano Hydroxyapatite using SEM/EDX – An in vitro study2019 •
International Journal of Pharmaceutical Investigation
Treatment modalities and evaluation models for periodontitis2012 •
Revista Brasileira de Ciências Farmacêuticas
Periodontal pocket drug delivery systemsRevista Brasileira de Ciências Farmacêuticas
Sistemas de liberação de fármaco intrabolsa periodontal2006 •
International Journal of Environmental Research and Public Health
Clinical Effectiveness of Herbal Oral Care Products in Periodontitis Patients: A Systematic ReviewJournal of Clinical Periodontology
Significance of a simplified method for periodontal risk assessment in predicting periodontitis recurrence during supportive periodontal therapy: a retrospective cohort study2015 •
Journal of Proteome Research
Mass Spectrometric Analyses of Peptides and Proteins in Human Gingival Crevicular Fluid2010 •
2013 •
2019 •
Journal Of Clinical Periodontology
Body Mass Index as a predictor of preterm birth in pregnant periodontitis women