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Cureus
Romanian Journal of Medical Practice
COVID-19 – apiphytotherapeutic opportunities for prevention and treatment2020 •
2015 •
Nepalese Culture
The sacred Mahakala in the Hindu and Buddhist textsMahakala is the God of Time, Maya, Creation, Destruction and Power. He is affiliated with Lord Shiva. His abode is the cremation grounds and has four arms and three eyes, sitting on five corpse. He holds trident, drum, sword and hammer. He rubs ashes from the cremation ground. He is surrounded by vultures and jackals. His consort is Kali. Both together personify time and destructive powers. The paper deals with Sacred Mahakala and it mentions legends, tales, myths in Hindus and Buddhist texts. It includes various types, forms and iconographic features of Mahakalas. This research concludes that sacred Mahakala is of great significance to both the Buddhist and the Hindus alike.
2015 •
The effect of vitamin A on mucosal immunity has never been subjected to extensive studies until recently. We started to work in this area in the early 1970s when we observed that children with protein-calorie malnutrition (PCM) often had defective mucosal immunity, judging from the incidence of respiratory tract infections and diarrhea. We reported that these children had depressed secretory IgA (sIgA) levels in their nasal wash fluids. The IgA level in specimens collected from those superimposed with some degrees of vitamin A deficiency state appeared to be more severely affected. In order to better understand the underlying mechanism associated with this condition, we started to study more detail the deficiency state using experimental vitamin A-deficient rats. From a series of experiments using this animal model, we proposed that vitamin A was needed for transport and/or secretion of sIgA across the mucosa. This conclusion was based on the observation that the secretory component of sIgA synthesized by the epithelial cells of these vitamin A deficient animals was adversely affected as compared to the control animals. From that time onward, much progress has been made by several other groups showing that other mechanisms could also influence the integrity and immune function of the mucosa. For instance, recent studies demonstrated that retinoic acid which is a biologically active form of vitamin A has an essential role in mucosal homeostasis, controlling tolerance and immunity in these non-lymphoid tissues. Such a conclusion was made possible by the availability of sophisticated new molecular biology and genetic engineering techniques together with advances in the field of immunoregulation, e.g., the discovery of dendritic cells (DCs) and T helper cell subsets in 1980s, and the role of Toll-like receptors (TLRs) together with other innate immune regulators in controlling adaptive immune response in the early 1990s. These advances provided considerable new insights into the pleiotropic roles of vitamin A including educating mucosal DCs, differentiation of lymphocyte lineages and imprinting them with mucosal-homing properties as well as in regulating tolerance and immunity. The identification of a novel lymphocyte subpopulation, innate lymphoid cells (ILCs), at the beginning of this century has provided us with an additional insight into a new role of vitamin A in regulating homeostasis at the mucosal surface through influencing ILCs. Another new player that regulates intestinal homeostasis and mucosal immune response is microbiota whose composition is known to vary with vitamin A status. So it appears now that the role of vitamin A on mucosal immunity is far beyond regulating the adaptive Th1-Th2 cell response, but is highly pleiotropic and more complicating, e.g., polarizing the phenotype of mucosal DCs and macrophages, directing gut-homing migration of T and B cells, inducing differentiation of effector T cells and Treg subpopulation, balancing mucosal ILCs subpopulation and influencing the composition of microbiota. In this review, I will attempt to bring together these important advances to provide a comprehensive and contemporary perspective on the role of vitamin A in regulating mucosal immunity.
2021 •
Proteomics of pericardial fluid from patients with ischemic heart disease having impaired systolic function.
Journal of Applied Physics
Annealing effects on structural and transport properties of rf-sputtered CoFeB∕MgO∕CoFeB magnetic tunnel junctions2006 •
Annealing effects on the structural and transport properties of sputtered CoFeB∕MgO∕CoFeB magnetic tunnel junctions deposited on SiO2∕Si were investigated. At the as-deposited state, the CoFeB was amorphous at the CoFeB∕MgO interface. High-resolution transmission electron microscope image clearly shows that after annealing at 270°C for 1h, crystallization of amorphous CoFeB (three to four monolayers) with lattice matching to MgO (100) occurred locally at the interface between MgO and CoFeB, producing a magnetoresistance (MR) around 35%–40%. After annealing at 360°C for 40min, the MR increased to 102%. The increase in the MR with annealing is attributed to the complete formation of (100) crystalline structure of CoFeB well lattice matched with the (100)-oriented MgO barrier. The bias voltage dependence of the MR shows a consistent correlation with each CoFeB∕MgO interface.
UWS毕业证书办理西悉尼大学假文凭定制Q微168899991做UWS留信网教留服认证海牙认证改UWS成绩单GPA做UWS假学位证假文凭高仿毕业证申请西悉尼大学University of Western Sydney degree offer diploma Transcript
Educational Administration: Theory and Practice
Examining High School Students’ Perceptions of Democratic School Culture2015 •
2019 •
L'informatique musicale, recherche en science et art du traitement automatise d'informations musicales, rassemble une communaute vivante de chercheurs et d'enseignants-chercheurs, ingenieurs, artistes et pedagogues. Ce document partage quelques reflexions epistemologiques sur ce domaine par nature interdisciplinaire (parties 1 a 3) et propose des resultats preliminaires d'une cartographie de ces recherches en France (parties 4 et 5). 1. AUX SOURCES DE L'INFORMATIQUE MUSICALE La science et la musique ont toujours eu des liens forts, tout d'abord sur des aspects de gammes et d'acoustique. Le Quadrivium fut defini par Boece au VI e siecle et re-groupe les arts liberaux des « sciences des nombres », a savoir l'arithmetique, la musique, la geometrie et l'astro-nomie. L'harmonie des spheres, liant proportions celestes et musique, est une des theories pythagoriciennes etudiees par Boece [4]. Mille ans plus tard, notamment a partir des ouvrages de Zar...
Acta Numismatica Hungarica
A rare Byzantian medallion of Gordian III from the legionary fort of Brigetio2024 •