Grass pea consumption & present scenario of neurolathyrism in Maharashtra State of India

Global Journal of Science Frontier Research

Grass pea can be consumed as supplementary nutrients in a diet without a neurolathyrism health problem among all classes of people in the south-central coastal area of Bangladesh. The study aimed at assessing the grass pea consumption pattern in diet and detection of neurolathyrism patients over 400 respondents among four villages. An investigation was also done on various paralytic admitted patients at hospital in the south central coastal region of Bangladesh. Among respondents of four villages 63% were male, 38.75% was illiterate, 41.5% was completed primary education and 30% of respondent’s monthly income Tk. 6000-9500 was maximum. Among respondents 89.6% consumed grass pea was 1/3 or less than cereal at its proportion in a meal and they all consumed meat, fish, egg, vegetables also. In grass pea food items 25.25% respondents prefer Dal barta was maximum and Dobakhesari (snack) 0.75% was lowest. 95.75% respondent was used various spices like onion, garlic, chili, tamarind etc. w...

Tropical Medicine and International Health, 2005

Food and Chemical Toxicology, 2010

Food and Chemical Toxicology, 2011

Food Chemistry, 2008

Neurolathyrism is past history in India since Lathyrus sativus (khesari dal) is no longer used as a staple. A consensus has evolved that khesari dal is harmless as part of a normal diet. L-ODAP (β-N-oxalyl-l-α-diamino propionic acid) the neurotoxic amino acid, from this pulse, is detoxified in humans but not in animals but still no laboratory animal is susceptible to it under acceptable feeding regimens. L-ODAP is an activator of protein kinase C and consequential crucial downstream effects such as stabilization of hypoxia inducible factor-1 (HIF-1) could be extremely conducive to humans under a variety of situations. ODAP is gradually finding a place in several patents for this reason. Homoarginine the second amino acid from L. sativus can be a better substrate for endogenous generation of nitric oxide, a crucial signaling molecule associated with the cardiovasculature and control of hypertension. These features could make L. sativus a prized commodity as a functional food for the general cardiovasculature and overcome hypoxic events and is set to change the entire perception of this pulse and neurolathyrism. Neurolathyrism The disease neurolathyrism is now history and may never be a challenge in the future in view of the vast public awareness and governmental and infrastructural capabilities. The present review highlights the recent thoughts on this disease and how a certain dignity can be restored to Lathyrus sativus (Khesari dal also known as grass pea) which indeed has been a saviour for vast populations under severe drought and famine situations in several countries around the world. A causal relationship between the excessive consumption of L. sativus and neurolathyrism, an upper motor neuron disorder characterized by a spastic paraparesis of the lower limbs is well known since several decades 1. Neurolathyrism has always surfaced only during extreme situations such as famine and drought when other food crops are in short supply resulting in an exclusive consumption of the pulse almost as a staple for prolonged periods lasting as long as 3-6 months. The disease affects only a very small percentage of the population 2 and in its absence large

Foods

Grass pea (Lathyrus sativus L.), an indigenous legume of the subcontinental region, is a promising source of protein and other nutrients of health significance. Contrarily, a high amount of β-N-oxalyl-l-α,β-diaminopropionic acid (β-ODAP) and other anti-nutrients limits its wider acceptability as healthier substitute to protein of animal and plant origin. This study was aimed at investigating the effect of different processing techniques, viz. soaking, boiling, germination, and fermentation, to improve the nutrient-delivering potential of grass pea lentil and to mitigate its anti-nutrient and toxicant burden. The results presented the significant (p < 0.05) effect of germination on increasing the protein and fiber content of L. sativus from 22.6 to 30.7% and 15.1 to 19.4%, respectively. Likewise, germination reduced the total carbohydrate content of the grass pea from 59.1 to 46%. The highest rate of reduction in phytic acid (91%) and β-ODAP (37%) were observed in germinated grass...

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2002

The virtual congress on brain health innovation and technologies , 2020

Background Consumption of medicinal plants as food furnishes Phyto-nutrition to the human body and improves their wellbeing due to a combination of bio-metabolites. Worldwide in a traditional medication systems including Bangladesh, medicinal plants have been applied as both neuro-therapeutic purposes and nutrients provider for the wellbeing of psychological states e.g. anti-depressant, anti-anxiety, anti-convulsions, anti-dementia, antipsychotic, and cognitive enhancement, etc. Objective The present study aimed to compile ethnomedicinal plant-based functional foods used by folk medicine practitioners (FMPs) of Bangladesh for the management of brain health. Method By using online databases like PubMed, Google Scholar, ResearchGate, and Elsevier to retrieve literature by applying multiple keywords such as “ethnomedicinal plants, functional foods, Bangladesh”. The listed plants were then evaluated by using relevant pharmacological studies to claim their neuroprotective properties. Results A total of 32 medicinal plants have been listed that were used by FMPs as functional foods for the management of multiple neurology-related ailments. The study it showed that Plants like Aegle marmelos, Bacopa monnieri, Centella asiatica, Clitoria ternatea, Mentha arvensis, Moringa oleifera, Spilanthes acmella, Syzygium aromaticum, Syzygium cumini, Terminalia chebula, and Vitex negundo pharmacologically also possessed neuroprotective properties. Conclusion Plant-based foods are an emerging interest thanks to their nutritional support and therapeutic benefits, and some ethnomedicinal plants of Bangladesh which were classified as functional foods have also been biologically reported to have several neurological health benefits. Our study will help the scientific communities to conduct further research to develop therapeutic guidelines that are needed to ensure unquestionable safety appraisal.

Marina Coimbra Casadei Barbosa da Silva, 2024

abordam criticamente a estética da sensibilidade, um dos fundamentos educacionais pós-reforma de 1996. A pesquisa de doutorado subjacente abordou a falta de clareza e complexidade na conceituação desse princípio educacional ao longo do tempo. A autora busca resgatar a essência filosófica da estética da sensibilidade, questionando interpretações contemporâneas que a reduzem a um instrumento de preparo emocional para o mercado de trabalho. A conclusão propõe uma compreensão mais profunda, apresentando a estética da sensibilidade como uma arte de harmonizar o sentir e o pensar. O texto estabelece um diálogo com leituras decoloniais, revelando uma perspectiva de educação emancipatória e humanizadora. A estética da sensibilidade é apresentada como um método educativo para formar sujeitos críticos e reflexivos, não como uma ferramenta para conformidade com o status quo. Ao conectar a estética da sensibilidade aos conceitos de sentipensar e corazonar do pensamento decolonial, a autora desafia interpretações simplistas e propõe uma visão renovada da educação. O livro é considerado uma contribuição significativa para a Filosofia da Educação, refletindo sobre os fundamentos que moldam a formação dos indivíduos em um contexto em constante transformação, convidando a repensar a educação para uma sociedade mais justa e humanizada.