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AIDS Behav. Author manuscript; available in PMC 2021 August 01.
Published in final edited form as:
AIDS Behav. 2020 August ; 24(8): 2327–2335. doi:10.1007/s10461-020-02792-7.
Sex partner behavior variation related to network position of and
residential proximity to sex partners among young black men
who have sex with men
Yen-Tyng Chena,b, Rodal S. Issemaa,b, Anna Hottona,b, Aditya S. Khannaa,b, Babak M.
Ardestania,b, John A. Schneidera,b,c, Abby Rudolphd
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aChicago
Center for HIV Elimination, Chicago
bDepartment
of Medicine, University of Chicago
cDepartment
of Public Health Sciences, University of Chicago
dDepartment
of Epidemiology and Biostatistics, College of Public Health, Temple University
Abstract
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This analysis examines how sex behaviors are influenced by a sex partner’s network bridging
position and the residential proximity between the two. The study sample consisted of 437 young
black men who have sex with men (YBMSM) in Chicago and their sex partners (2013-2014).
Dyadic analyses that clustered on individuals using generalized estimating equations (n=1095
relationships) were conducted to assess the associations between different HIV-related sexual
behaviors and the network position of and residential proximity to a partner. The odds of group sex
was higher with partners who had high network bridging, regardless of how close they lived to one
another. The odds of transactional sex was higher with partners who had high network bridging
and lived in a different region of the city. Sex behaviors associated with an increased risk of HIV
transmission were associated with the network structural position of and residential proximity to
partners among YBMSM.
Keywords
men who have sex with men; sexual behaviors; social network analysis; African-American;
geography
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INTRODUCTION
Young black men who have sex with men (YBMSM) bear a significant burden of the HIV
epidemic in the United States. As estimated, 1 in 2 YBMSM are expected to be infected by
HIV during their lifetime (1). Evidence has shown that the high HIV infection risk among
YBMSM is not explained by individual-level risk behaviors (2). YBMSM often engage in
less condomless sex, less drug use during or prior to sex, and have fewer sex partners
Corresponding author: Yen-Tyng Chen, Department of Medicine, University of Chicago, 5841 S Maryland Ave, MC 5065, Chicago,
IL 60637, Tel: 773-702-9977, Fax: 773-702-8998, ychen22@medicine.bsd.uchicago.edu; yenting1219@gmail.com.
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compared to their white counterparts (3, 4). Accordingly, the high HIV infection risk among
YBMSM may be in part due to an interaction between the people with whom they interact
and places where they spend time (2, 5–8). There is a growing emphasis on the need for
research to understand factors that increase HIV risk among YBMSM from both network
and spatial perspectives (5).
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Network factors may explain the increased HIV burden among YBMSM in the context of
safer sex behaviors (3, 9). Past research among YBMSM has found that HIV-related sex
behaviors with a partner may be influenced by the demographic characteristics of their sex
partner (e.g., age, race), partner type, and assortative mixing on risk behaviors (e.g.,
individuals who use drugs during or prior to sex also have a sex partner who also uses drugs
during or prior to sex) (3, 7, 10, 11). The role of network structural position has recently
been highlighted as relevant for HIV prevention and intervention among YBMSM (12–15).
Individuals who hold bridging positions connect people who are not directly in contact with
one another. Thus, those who act as network bridges can facilitate HIV transmission or the
flow of intervention information between two distinct clusters of people who would
otherwise not be connected (12, 16). In the context of HIV prevention, bridging positions
have been used to select peer change agents to diffuse HIV pre-exposure prophylaxis (PrEP)
prevention information because people who are a bridge are more likely to exhibit leadership
traits within their networks and are able to intervene with MSM not typically identified
within HIV prevention intervention (12, 15, 17).
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From a spatial perspective, the HIV burden is often clustered in specific geographic areas
and HIV clusters are often more common in neighborhoods that are predominately Black/
African American. Geographic proximity to an HIV “hot spot” plays an important role in
HIV transmission. For example, in Chicago, the south side neighborhoods have the highest
HIV prevalence and are also the areas where most YBMSM reside or spend time. If
YBMSM select sex partners who also reside or spend time in the same high burdened
neighborhoods or who are of the same race, the risk of HIV acquisition could be higher
because the probability of partners being HIV-infected is higher in both of these scenarios.
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Furthermore, an individual’s HIV transmission behaviors may differ based on whether or not
a partner is a bridge and/or whether the two reside in the same neighborhood. Bridging
relationships may include weaker ties than non-bridging relationships and bridging
relationships may decay faster than non-bridging relationships (18). Therefore, bridging
relationships tend to be less stable in terms of both duration and strength. In addition,
geography can act as a boundary that fosters or constrains the formation of sex partnerships
(19, 20), which in turn may also influence the strength of the relationship and the risk
behaviors in which the two engage. Residing in close geographic proximity to a sex partner
may result in relationships with more mutual control and commitment in part due to the
shared physical/social environments (e.g., the partner knows a person’s family and friends in
the area) (21). For example, having a sex partner living in close geographic proximity and
who have common sex partners may increase mutual trust and familiarity and may, in turn,
be associated with less likelihood of engaging in sexual behaviors that could increase the
risk of HIV transmission/acquisition (21, 22). This scenario can occur in places like South
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Chicago (the largest contiguous urban black community in the US) (23) where BMSM in
this area are predominately longtime residents (19).
Although past research has suggested that sexual behaviors are influenced by both network
features and space, limited research has examined how an individual’s sexual behaviors with
a partner may be influenced by the partner’s network structural position and the residential
proximity between the two. In this paper, we examine how a sex partner’s network bridging
position and the residential proximity between an individual and their sex partner may be
associated with an individual’s sexual behaviors with that partner. We hypothesize that
condomless anal sex, using drugs during sex, group sex, transactional sex, and
serodiscordant partnerships are more common with sex partners who are network bridges
and who do not live in the same area than with sex partners who are not network bridges and
who reside in the same area.
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METHODS
Sample and Data Collection
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The data for this analysis were collected through a baseline assessment (n=618, 2013-2014)
in the uConnect Study, a longitudinal cohort study which examined behavioral and social
correlates of HIV among YBMSM in Chicago. The methods of uConnect have been
described in detail elsewhere (9). In brief, respondent-driven sampling was used to recruit
YBMSM who spent a majority of their time in South Chicago. Collectively, this region is
one of the largest Black communities in the US and has a high HIV prevalence (23, 24).
Study respondents were eligible to participate if they 1) self-identified as African American
or Black, 2) were assigned male sex at birth, 3) were between 16 and 29 years of age, 4)
reported oral or anal sex with a male within the past 24 months, 5) spent the majority of their
time in South Chicago, and 6) were willing and able to provide informed consent at the time
of the study visit. For this analysis, we excluded participants who identified as female and/or
transgender (n=48).
UConnect used a personal network inventory to collect the names (i.e., first name, last name,
and nick name) of both confidants and sex partners over the past 6 months through an
interviewer-administered survey. The current analysis focused only on the sex network.
Specifically, participants were asked, “thinking back over the past six months, that is since
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[month], how many people, including men, women, and transgender women have you had
sexual activity with, even if only one time?” Once the names of the sex partners were
generated, participants were asked to describe each partner with respect to demographic
characteristics (e.g., age, race, and sexual orientation), relationship-level characteristics (e.g.,
type of sex partner), and sexual behaviors with that partner (e.g., group sex, transactional
sex, drug use during or prior to sex). We additionally asked each individual to report on
whether the sex partners listed were known to have sex with one another. We used a fuzzy
matching algorithm as previously described (13) to determine when a sex partner named was
also a study participant. Furthermore, we added the sexual relationships that existed between
named sex partners based on the network inventory survey questions. The resulting
sociometric network consisted of all connections that exist between study participants in
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addition to the ties that exist between named sex partners. Institutional Review Board
approval was obtained for the study protocols.
Measures
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Network bridging position.—To measure bridging, we used Burt’s constraint score.
Valente and Fujimoto suggest that Burt’s constraint score can be a measure for bridging
when complete network information is not available (16). The constraint measure, proposed
by Burt, is a technique to identify “structural holes” in a social network (25). Structural
holes are individuals who connect non-redundant sources of information in a social network.
A constraint index measures an individual’s access to structural holes. (26) A lower
constraint score indicates an individual whose access to information is less constrained, and
therefore represents higher network bridging. A higher constraint score indicates an
individual whose access to information is more constrained, and therefore represents lower
network bridging. The influenceR package in R was used to compute the constraint measure
(27). Network bridging position was dichotomized based on the distribution of the constraint
score with a cut-off score at 1. High network bridging was defined by constraint scores
lower than 1 (around the lowest 20% of the constraint scores).
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Residential proximity.—We asked participants to report their and their sex partners’
home locations (e.g., cross-streets, neighborhoods). If participants were homeless, we asked
the locations where they had slept most often in the past 7 days. Residential proximity was
defined as whether a sex partner lived in the same “Chicago region” as the participant.
Chicago is divided into 9 “regions” based on the 77 well-established Chicago community
areas. The regions represent subdivisions of the city and generally reflect the socioeconomic
environments of the community areas that make up the Chicago region. For example, the
“south side region” is comprised of 12 Chicago community areas and is one of the most
socially and economically disadvantaged areas in Chicago. Because most participants did
not provide complete addresses for their and their sex partners’ home locations, we included
participants and their sex partners where their residential “Chicago region” or their
residential proximity can be identified so more participants and their sex partners could be
included in the analysis. An important consideration for this analysis is that although the
uConnect Study participants were only eligible to participate in the study if they lived in or
spent a majority of their time in South Chicago (i.e., includes the south region, southeast
region, and southwest region), partners could live anywhere in Chicago. Consequently, 72%
of the sex dyads reside in distinct Chicago region. Two hundred twenty-seven sex partners
(i.e., 17% of the 1322 sex partners listed in the personal network inventory) were dropped
from the analyses due to missing information on their residential location, as this
information was required to compute dyad residential proximity.
Combined bridging position and residential proximity.—We created a categorical
variable with four categories to represent the unique combinations of residential proximity
and bridging position for each sex partner. Sex partners were categorized as: (1) low network
bridging and live in the same region of Chicago, (2) low network bridging and do not live in
the same region of Chicago, (3) high network bridging and live in the same region of
Chicago, and (4) high network bridging and do not live in the same region of Chicago.
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Outcomes.—We measured five dichotomous outcomes which were defined as whether or
not participants engaged in each of the following sexual behaviors with each listed sex
partner in the past 6 months: any condomless anal sex (yes vs. no), using drugs during or
prior to sex (defined as using non-injection drug or alcohol during or prior to sex; yes vs.
no), any group sex (yes vs. no), any transactional sex (defined as paying or receiving money,
drugs, shelter, or other good for sex; yes vs. no), and serodiscordant or serostatus unknown
partnerships (yes vs. no). A serodiscordant or serostatus unknown partnership was defined as
those with at least one person in the relationship living with HIV or having an unknown
serostatus (individual or sex-partner) while the other was not living with HIV. Individual
study participant’s HIV status was confirmed through testing during survey and sex partners’
HIV status was based on a report from the individual who listed them (i.e. the participant’s
perception of their partner’s HIV status). All of these five outcomes were at the individual
level and were reported for each specific sex partner.
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Covariates.—We included participants’ demographic characteristics, including age,
educational attainment, sexual orientation, annual income, housing instability (measured by
“what type of residence do you currently live in” and defined as rented room in hotel, stayed
in shelter/halfway house, stayed in an apartment/ house for which they did not pay rent or
they did not own or had no regular residence), having more than one main partner (yes vs.
no), HIV status based on testing during survey visit, and sexual concurrency. Sexual
concurrency was defined as the count of sexual partnerships within the past 6 months that
overlapped based on the month and year of the first and last sexual intercourse with each sex
partner. For sex partner characteristics, we included sex partners aged ≥10 years older than
the participant, sex partner’s gender, and whether sex partner is the main partner. We also
controlled for whether a sex partner was also a study participant or listed as a confidant (i.e.
more than one relationship role).
Analysis
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Descriptive statistics of socio-demographic characteristics of the participants and their sex
partners were summarized. Chi-square statistics (and Fisher’s Exact tests when cell counts
were below 5) were used to assess statistically significant differences in partner
characteristics across groups. Bivariate analyses were conducted to explore factors
associated with each of the behavioral outcomes. Multivariable logistic regression analyses
were performed to determine the joint effect of the partner’s bridging network position and
residential proximity on the behavioral outcomes in each relationship using STATA 14.2
(StataCorp LP, Texas), was used To account for the fact that individuals reported multiple
sex partners, we used a generalized estimating equation (GEE) logistic regression model
with an exchangeable correlation structure and robust estimation of standard errors. The
correlations from the exchangeable structure in the GEE model were 0.25 for condomless
anal sex, 0.49 for sex drug use, 0.20 for group sex, 0.11 for transactional sex, and 0.32 for
serodiscordant or serostatus unknown.
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RESULTS
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Our sample included 437 individuals and 1095 sex partners (125 out of 1095 were also study
participants) from the baseline study. Specific to this sample, the overall mean age of study
participants was 23 (range 16-29), 67% identified as gay, 24% had unstable housing at the
time of completing the survey, 41% were HIV-positive, and the mean count of sexual
partnerships that overlapped with another sexual partnership was 1.6 (Table 1). Table 2
shows the characteristics of sex partners stratified by sex partners’ network bridging and
residential proximity to the study participant who listed them. Among the four strata of
network bridging and residential proximity, the largest group is comprised of sex partners
who had low network bridging and who lived in a different region of Chicago from the
individual who listed them (n=647; 60 % of all sex partners); the smallest group is
comprised of sex partners who had a high network bridging position and who lived in the
same region of Chicago as the individual who listed them (n=98; 9% of the total sex
partners). The distribution of sex partner gender and presence of alcohol or drug use during
or prior to sex between sex partner and the individual who listed them were similar across
the four strata; the distribution of sex partner’s age, whether sex partner was the main
partner, whether the sex partner was also a confidant, condomless anal sex, group sex, and
serodiscordant or serostatus unknown partnership significantly varied across the specific
combinations of network bridging and residential proximity. For example, group sex was
more common with sex partners who had a higher network bridging scores (18%-21%) than
it was with sex partners who had a low network bridging score (about 6%). The proportion
of sex partners who were transactional partners was higher among sex partners who lived in
a different region of Chicago (9-11%) than it was among sex partners who lived in the same
region of Chicago (about 5%) as the participant.
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After adjusting for individual and sex partner characteristics, Table 3 displays the odds of
engaging in different sexual behaviors with that partner based on the sex partner’s network
position and whether the two lived in the same or different regions of Chicago. Individuals
had a higher odds of engaging in group sex with sex partners who had a high network
bridging position, regardless of whether or not they lived in the same region of Chicago. The
adjusted odds ratio was 4.33 (95% CI: 1.52-12.35) times higher for sex partners who had a
high network bridging position and lived in the same region of Chicago as the participant
who listed them versus for sex partners who had a low network bridging position and lived
in the same region of Chicago; the adjusted odds ratio was 3.73 (95% CI: 1.39-10.06) times
higher for sex partners who had a high network bridging and lived in a different region of
Chicago versus for sex partners who had a low network bridging position and lived in the
same region of Chicago. Individuals had a higher odds of engaging in transactional sex with
sex partners that had a high network bridging position and lived in a different region of
Chicago (AOR=2.77, 95% CI: 1.07-7.18). The sex partner’s network position and/or
residential proximity to the participant were not significantly associated with condomless
anal sex, using alcohol or drugs during or prior to sex, or having serodiscordant or serostatus
unknown sex partnerships.
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DISCUSSION
Our findings demonstrate that YBMSM in Chicago have a higher odds of engaging in
transactional sex with sex partners that are network bridges and live in a different area of
Chicago. In addition, we found that group sex was more likely with partners who had high
network bridging positions and that this association did not differ for partnerships where
both lived in the same neighborhood vs. different neighborhoods.
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With respect to transactional sex, being a bridge and not living in close proximity may make
the sexual relationship weaker and more unstable. A sex partner who is living in a distinct
neighborhood and who occupies a bridging position may have fewer mutual friends with the
participant and may have more sex partners who are part of a distinct network from the
participant. Both the lack of mutual acquaintances and distinct networks of sex partners
could be associated with higher risk transactional sex among the pair. By unpacking this
transactional relationship further, we found that participants were more likely than their
partners (who had high bridging positions) to be the ones receiving money or other goods;
participants were also younger and more likely than their sex partners to live in more
disadvantaged neighborhoods, to make less money, to have unstable housing. Thus,
participants in more vulnerable positions (i.e., live in more disadvantaged neighborhoods,
have fewer resources) were more likely to exchange sex for goods or money with partners
who had more connections to non-mutual contacts. In this context, the participant may be
less able to negotiate safer behaviors and could potentially be a greater risk for HIV
acquisition with a person who is well-connected to distinct networks of people. This finding
is broadly consistent with past research suggesting that both individual and structural social
and economic disadvantage are associated with a greater likelihood of transactional sex as a
means to gain access to basic needs or access to a particular social community (28–30). Our
findings highlight the need for future research that further examines the relationship of both
social and spatial bridges with transactional sex among YBMSM.
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Our findings on the relationship between bridging position and group sex behavior provide
new insights. Regardless of a sex partner’s residential proximity, we found that YBMSM
had a higher odds of engaging in group sex with sex partners who occupied a bridging
position. This indicates that group sex may not necessarily be more likely to happen with
bridging sex partners. Rather, group sex is more likely to happen with a sex partner who has
few interconnected sex partners and more otherwise unconnected sex partners. Individuals
can quickly be introduced to other anonymous sex partners or sex partners who are less
known to the individuals through the bridging sex partner in the group sex events or sex
parties. However, the mechanism through which bridging position is associated with group
sex is contrary to what we would expect (i.e., we expect that engage in group sex through a
bridge whom an individual is less likely to know). We found that participants had a higher
odds of engaging in group sex with sex partners who were also listed as their confidant and
were 10 years older than them. It is possible that individuals may be more comfortable to
seek previous unconnected sex partners during group sex events or parties through someone
they already know. It is also possible that participants had to name sex partners and those
named sex partners were more likely well known than those who were not named, who they
had forgotten, or who were anonymous. However, further examination is needed to further
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understand the contexts of group sex based on the interplay between network position and
space.
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We did not find differences in condomless anal sex, using drugs during sex, and
serodiscordant sexual partnerships based on the network position of the partner or the
residential proximity between the pair. Condomless anal sex and using drugs before or
during sex may be more strongly influenced by the perceived risk of HIV transmission/
acquisition with a particular partner based on individual (i.e., their own HIV status and viral
load, whether or not they are on PrEP) and partner attributes (i.e., perceived HIV status, viral
load of HIV positive partner, etc.). For example, past research has indicated that YMSM use
rational decision-making strategies to decide whether to engage in condomless anal sex by
calculating the risk of HIV transmission based on partners’ PrEP use or viral load (31). As
seen in Table 3, individuals had a higher odds of engaging in condomless anal sex with main
partners and confidants, suggesting that relationship-level attributes such as trust, intimacy,
etc. may also play a role in an individual’s decision regarding condom use. Similarly, using
drugs during sex has also been shown to be related to an individual-level decision-making
processes in which MSM consider both psychological and physical concerns (e.g., increased
sexual pleasure during both receptive and insertive anal sex) (32). Study participants mostly
spent their time in the south side region of Chicago, which is the region with the highest
prevalence of HIV infection (24). In terms of serodiscordant partnerships, it is possible that
individuals’ or sex partners’ PrEP use or use of antiretroviral (ART) medicines may
influence the decision regarding engaging sex with a serodiscordant or serostatus unknown
partner. In the current sample, less than 5% of HIV negative participants had ever used PrEP;
among HIV positive participants, 50% had ever used ART and about 23% reported that they
were virally suppressed. As we did not have information on the PrEP use and the ART use
for sex partners who were not also study participants, we were not able to further explore
how engagement in care may play a role in risk behaviors within serodiscordant
partnerships.
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A few limitations should be acknowledged. In order to examine sexual behaviors by a sex
partner’s network bridging score and a sex partner’s residential proximity to the individual,
we created binary variables to categorize each sex partner based on their network bridging
value (high constraint vs. low constraint) and their residential proximity (same Chicago
region vs different Chicago region). For the residential proximity variable, we were not able
to use the actual geographic distance in miles or travel time in minutes between members of
a dyad because most participants did not provide full address information for themselves and
their sex partners. Participants mostly provided cross-street, neighborhoods, or Chicago
community areas information for their and their sex partners’ home location. Therefore, we
used the Chicago region which represents a cluster of neighborhoods with similar social and
cultural characteristics. We compared those who were missing residential information and
excluded in the analysis with those who were included in the analysis. There were some
differences in those who were missing residential information (e.g., less likely to be main
partners). However, these factors were controlled in the analysis. Our data only permitted
examination of the residential proximity between the two individuals’ residential areas. It is
possible that sexual behaviors take place somewhere other than the participant’s or sex
partner’s home, particularly with group sex. However, we did not have information on the
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locations where partners met one another or where group or transactional sex took place. In
terms of the network construction, not all the sex partners were participants in the study and
the sexual partnerships between each listed sex partner were based on the report from study
participants. Thus, those who were study participants were more likely to have more central
network positions due to the matching protocol. However, this is accounted for with a
covariate in the final model. Additionally, anonymous partners may be named by individual
study participants, but these anonymous partners are less likely to match and therefore less
likely to hold network bridging positions. It has been previously noted that unobserved
relationships between the named sex partners across study participants can bias the
construction of network position. Although a method for imputing missing data has been
suggested to alleviate such a bias (15), we were not able to impute the missing relational
data because the relational information between each of the sex partners across network
clusters was unavailable.
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Despite these limitations, our findings demonstrate how residential proximity between sex
partners and the sex partner’s network position may influence the sexual behaviors between
the pair. HIV prevention interventions may target YBMSM who have a greater opportunity
to bridge connections between people and promote the use of condoms and PrEP.
Furthermore, PrEP linkage services should also incorporate supportive resources for housing
and employment to empower those who have fewer resources, especially in neighborhoods
that have been historically marginalized due to racism, such as the south side region of
Chicago. This study highlights the need to further understand how YBMSM’s sexual
behaviors are influenced by residential proximity to partners and partnerships with those
who hold bridging positions within the larger networks.
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Acknowledgment:
We would like to thank the uConnect study participants for the time they contributed to this study. We would also
like to thank the staff for the collection of the data. This study was funded by the National Institutes of Health
[grant numbers, R01 DA033875, R01 MH112406, R01 DA039934]. The funding sources did not have involvement
in the development of this work.
Reference
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1. CDC. HIV infection risk, prevention, and testing behaviors among men who have sex with men—
national HIV behavioral surveillance, 20 U.S. cities, 2014. HIV Surveillance Special Report.
2016;15.
2. Sullivan PS, Rosenberg ES, Sanchez TH, Kelley CF, Luisi N, Cooper HL, et al. Explaining racial
disparities in HIV incidence in black and white men who have sex with men in Atlanta, GA: a
prospective observational cohort study. Ann Epidemiol. 2015;25(6):445–54. [PubMed: 25911980]
3. Millett GA, Peterson JL, Flores SA, Hart TA, Jeffries WL, Wilson PA, et al. Comparisons of
disparities and risks of HIV infection in black and other men who have sex with men in Canada,
UK, and USA: a meta-analysis. Lancet. 2012;380(9839):341–8. [PubMed: 22819656]
4. Millett GA, Flores SA, Peterson JL, Bakeman R. Explaining disparities in HIV infection among
black and white men who have sex with men: a meta-analysis of HIV risk behaviors. Aids.
2007;21(15):2083–91. [PubMed: 17885299]
5. Tieu H-V, Koblin BA, Latkin C, Curriero FC, Greene ER, Rundle A, et al. Neighborhood and
network characteristics and the HIV care continuum among gay, bisexual, and other men who have
sex with men. J Urban Health. 2018.
AIDS Behav. Author manuscript; available in PMC 2021 August 01.
Chen et al.
Page 10
Author Manuscript
Author Manuscript
Author Manuscript
Author Manuscript
6. Bauermeister JA, Connochie D, Eaton L, Demers M, Stephenson R. Geospatial indicators of space
and place: A review of multilevel studies of HIV prevention and care outcomes among young men
who have sex with men in the United States. J Sex Res. 2017;54(4-5):446–64. [PubMed: 28135857]
7. Schneider J, Cornwell B, Ostrow D, Michaels S, Schumm P, Laumann EO, et al. Network mixing
and network influences most linked to HIV infection and risk behavior in the HIV epidemic among
black men who have sex with men. Am J Public Health. 2013;103(1):e28–e36.
8. Chen Y-T, Kolak M, Duncan DT, Schumm P, Michaels S, Fujimoto K, et al. Neighbourhoods,
networks and pre-exposure prophylaxis awareness: a multilevel analysis of a sample of young black
men who have sex with men. Sex Transm Infect. 2018:sextrans-2018-053639.
9. Schneider J, Cornwell B, Jonas A, Lancki N, Behler R, Skaathun B, et al. Network dynamics of HIV
risk and prevention in a population-based cohort of young Black men who have sex with men –
CORRIGENDUM. Netw Sci. 2017;5(2):247-.
10. Hurt CB, Matthews DD, Calabria MS, Green KA, Adimora AA, Golin CE, et al. Sex with older
partners is associated with primary HIV infection among men who have sex with men in North
Carolina. Journal of acquired immune deficiency syndromes (1999). 2010;54(2):185. [PubMed:
20057320]
11. Tieu H-V, Liu T-Y, Hussen S, Connor M, Wang L, Buchbinder S, et al. Sexual networks and HIV
risk among black men who have sex with men in 6 US cities. PLoS One. 2015;10(8):e0134085.
[PubMed: 26241742]
12. Schneider JA, Zhou AN, Laumann EO. A new HIV prevention network approach: sociometric peer
change agent selection. Soc Sci Med. 2015;125:192–202. [PubMed: 24518188]
13. Skaathun B, Voisin DR, Cornwell B, Lauderdale DS, Schneider JA. A longitudinal examination of
factors associated with network bridging among YMSM: Implications for HIV prevention. AIDS
Behav. 2018;23(5): 1326–38.
14. Morgan E, Skaathun B, Duvoisin R, Michaels S, Schneider JA. Are HIV seroconversions among
young men who have sex with men associated with social network proximity to recently or longterm HIV-infected individuals?J Acquir Immune Defic Syndr. 2018;77(2): 128–34. [PubMed:
29135652]
15. Khanna AS, Goodreau SM, Michaels S, Schneider JA. Using partially-observed Facebook
networks to develop a peer-based HIV prevention intervention: Case study. Journal of medical
Internet research. 2018;20(9).
16. Valente TW, Fujimoto K. Bridging: Locating critical connectors in a network. Social networks.
2010;32(3):212–20. [PubMed: 20582157]
17. Young LE, Schumm P, Alon L, Bouris A, Ferreira M, Hill B, et al. PrEP Chicago: A randomized
controlled peer change agent intervention to promote the adoption of pre-exposure prophylaxis for
HIV prevention among young Black men who have sex with men. Clinical Trials. 2017;15(I):44–
52.
18. Burt RS. Bridge decay. Social Networks. 2002;24(4):333–63.
19. Laumann EO, Ellingson SE, Mahay JE, Paik AE, Youm YE. The sexual organization of the city:
University of Chicago Press; 2004.
20. Zenilman JM, Ellish N, Fresia A, Glass G. The geography of sexual partnerships in Baltimore:
applications of core theory dynamics using a geographic information system. Sex Transm Dis.
1999;26(2):75–81. [PubMed: 10029979]
21. Youm Y, Laumann EO. Social network effects on the transmission of sexually transmitted diseases.
Sex Transm Dis. 2002;29(11):689–97. [PubMed: 12438906]
22. Fujimoto K, Williams ML, Ross MW. A network analysis of relationship dynamics in sexual dyads
as correlates of HIV risk misperceptions among high-risk MSM. Sex Transm Infect.
2015;91(2):130–4. [PubMed: 25305211]
23. United States Census Bureau. 2005-2009 American community survey 5-year estimates.
Washington, DC; 2011.
24. Chicago Department of Public Health. HIV/STI surveillance report. 2018.
25. Burt RS. Structural holes versus network closure as social capital In: N Lin, K Cook, RS Burt,
editors. Social capital: Theory and research: Routledge; 2001 p. 31–56.
26. Burt RS. Reinforced structural holes. Social Networks. 2015;43:149–61.
AIDS Behav. Author manuscript; available in PMC 2021 August 01.
Chen et al.
Page 11
Author Manuscript
Author Manuscript
27. Jacobs S, Khanna A, Kamesh M, David B. influenceR: Software tools to quantify structural
importance of nodes in a network 2015 [Available from: https://cran.r-project.org/web/packages/
influenceR/index.html.
28. Bauermeister J, Eaton L, Stephenson R. A multilevel analysis of neighborhood socioeconomic
disadvantage and transactional sex with casual partners among young men who have sex with men
living in metro Detroit. Behav Med. 2016;42(3):197–204. [PubMed: 27337624]
29. Bond KT, Yoon IS, Houang ST, Downing MJ, Grov C, Hirshfield S. Transactional sex, substance
use, and sexual risk: Comparing pay direction for an internet-based U.S. sample of men who have
sex with men. Sexuality Research and Social Policy. 2019.
30. Oldenburg CE, Perez-Brumer AG, Reisner SL, Mimiaga MJ. Transactional sex and the HIV
epidemic among men who have sex with men (MSM): Results from a systematic review and metaanalysis. AIDS Behav. 2015;19(12):2177–83. [PubMed: 25652233]
31. Newcomb ME, Mongrella MC, Weis B, McMillen SJ, Mustanski B. Partner disclosure of PrEP use
and undetectable viral load on geosocial networking apps: Frequency of disclosure and decisions
about condomless sex. Journal of acquired immune deficiency syndromes (1999). 2016;71(2):200–
6. [PubMed: 26761520]
32. Rich AJ, Lachowsky NJ, Cui Z, Sereda P, Lal A, Moore DM, et al. Event-level analysis of anal sex
roles and sex drug use among gay and bisexual men in Vancouver, British Columbia, Canada.
Arch Sex Behav. 2016;45(6):1443–51. [PubMed: 26525571]
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Table 1.
Author Manuscript
Participant characteristics, uConnect study 2013-2014 (n = 437 individuals)
Participant characteristics
Total
Age
22.9 ± 3.2
Sexual orientation
Gay
294 (67.4%)
Bisexual
130 (29.8%)
Straight/Other
12 (2.8%)
Less than high school education
Annual income less than $USD20,000
27 (6.2%)
342 (79.5%)
a
104 (23.9%)
Sexual concurrency for sex partners in the past 6 months
1.6 ± 1.0
Current housing instability
Author Manuscript
Number of sex partner
b
2.5 ± 1.4
More than one main partner
64 (14.6%)
HIV-positive
181 (41.4%)
a
Housing instability was defined as (1) rented room in hotel, (2) stayed in shelter or halfway house, (3) stayed in an apartment or house for which
they did not pay rent or they did not own, or (4) had no regular residence by the time to completion of the survey.
b
Each participant named up to 6 sex partners
Author Manuscript
Author Manuscript
AIDS Behav. Author manuscript; available in PMC 2021 August 01.
Author Manuscript
Author Manuscript
Author Manuscript
Author Manuscript
Table 2.
Chen et al.
Sex partner characteristics stratified by their network bridging and their residential proximity to the individual who listed them, uConnect Study,
2013-2014 (n= 1095 sex partners)
a
Low bridging & Same
Chicago region (n = 210)
Low bridging & Different
Chicago region (n = 647)
High bridging & Same
Chicago region (n = 98)
High bridging & Different
Chicago region (n = 140)
n (%)
n (%)
n (%)
n (%)
97 (8.9)
20 (9.6)
67 (10.4)
1 (1.0)
9 (6.4)
0.01
Male
945 (86.3)
187 (89.1)
542 (83.8)
91 (92.9)
125 (89.3)
0.06
Female
113 (10.3)
19 (9.1)
75 (11.6)
7 (7.1)
12 (8.6)
Sex partner characteristics
AIDS Behav. Author manuscript; available in PMC 2021 August 01.
Partner is ≥10 years older
Total
P-value
b
Partner gender
Transgender
Main partner
37 (3.4)
4 (1.9)
30 (4.6)
0 (0.0)
3 (2.1)
417 (38.7)
79 (38.2)
217 (34.2)
60 (61.2)
61 (43.6)
<0.001
Partner is also a study participant
125 (11.4)
0 (0.0)
0 (0.0)
66 (67.4)
59 (42.1)
<0.001
Partner is also a confidant
149 (13.6)
31 (14.8)
43 (6.7)
42 (42.9)
33 (23.6)
<0.001
First met through mobile applications
159 (14.6)
40 (19.1)
91 (14.1)
9 (9.2)
19 (13.6)
0.12
Condomless anal sex with individual
361 (33.1)
61 (29.3)
187 (29.0)
51 (52.0)
62 (44.3)
<0.001
Sex-drug use with individual
393 (36.0)
77 (36.8)
220 (34.2)
38 (38.9)
58 (41.4)
0.37
Group sex with individual
97 (9.3)
13 (6.5)
41 (6.6)
19 (20.9)
24 (17.8)
<0.001
Transactional sex with individual
92 (8.4)
12 (5.7)
59 (9.1)
5 (5.1)
16 (11.4)
Serodiscordant partnership or at least one
person has an unknown serostatus
468 (42.7)
97 (46.2)
288 (44.5)
35 (35.7)
48 (34.3)
0.14
0.048
a
Network bridging was measured by Burt’s constraint score. High network bridging was defined with constraint score that was lower than 1 (around the lowest 20% of the total constraint scores); low
network bridging was defined with constraint score that was greater than 1.
b
Chi-square test or Fisher’s Exact test for cell size under 5.
Page 13
Chen et al.
Page 14
Table 3.
Author Manuscript
Adjusted Odds of an individual engaging in specific sexual behaviors with a sex partner, uConnect Study,
2013-2014 (n = 1095 sex partners)
Condomless anal sex
Sex drug use
Group sex
Transactional sex
aOR (95% CI)
aOR (95% CI)
aOR (95% CI)
aOR (95% CI)
Sex partner characteristics
Network position & residential proximity
Low bridging & same Chicago region
1.00
1.00
1.00
1.00
Low bridging & different Chicago region
1.31 (0.90, 1.92)
0.85 (0.64, 1.14)
1.08 (0.51, 2.30)
1.41 (0.68, 2.93)
High bridging & same Chicago region
1.37 (0.64, 2.92)
1.29 (0.76, 2.18)
4.33 (1.52, 12.35)**
2.06 (0.56, 7.52)
High bridging & different Chicago region
1.24 (0.62, 2.49)
1.29 (0.84, 2.00)
3.73 (1.39, 10.06)*
2.77 (1.07, 7.18)*
0.63 (0.37, 1.06)
0.72 (0.45, 1.16)
3.44 (1.90, 6.23)***
3.34 (1.68, 6.64)***
Partner is ≥10 years older
Author Manuscript
Gender
Male
1.00
1.00
1.00
1.00
Female
0.19 (0.09, 0.40)***
1.29 (0.78, 2.12)
0.79 (0.38, 1.64)
0.96 (0.39, 2.36)
Transgender
0.28 (0.11, 0.70)**
2.34 (1.25, 4.38)**
0.33 (0.05, 2.34)
0.98 (0.23, 4.12)
Main partner
3.53 (2.49, 5.01)***
0.94 (0.73, 1.21)
0.72 (0.36, 1.45)
0.25 (0.12, 0.53)***
Partner was also a participant
1.48 (0.74, 2.98)
0.89 (0.55, 1.45)
0.30 (0.09, 1.00)*
0.50 (0.16, 1.62)
Partner was also an confidant
1.75 (1.12, 2.73)*
1.16 (0.81, 1.64)
5.45 (2.32, 12.81)***
0.82 (0.31, 2.15)
First met through mobile applications
0.92 (0.61, 1.38)
0.71 (0.49, 1.05)
0.24 (0.06, 0.99)*
0.74 (0.37, 1.49)
Age
0.98 (0.93, 1.04)
1.07 (1.01, 1.13)*
1.02 (0.94, 1.11)
1.08 (0.97, 1.20)
Less than high school
0.83 (0.37, 1.84)
1.20 (0.55, 2.63)
0.93 (0.26, 3.35)
1.22 (0.36, 4.10)
Participant characteristics
Author Manuscript
Sexual orientation
*
Gay
1.00
1.00
1.00
1.00
Bisexual
1.02 (0.68, 1.53)
0.92 (0.60, 1.41)
3.99 (2.03, 7.84)***
1.65 (0.85, 3.20)
Straight/other
1.41 (0.51, 3.88)
0.89 (0.27, 2.93)
1.78 (0.27, 11.82)
0.41 (0.07, 2.31)
Income (<$20,000)
0.71 (0.45, 1.11)
1.19 (0.73, 1.93)
0.73 (0.36, 1.48)
2.57 (1.03, 6.40)*
Housing instability
1.22 (0.80, 1.85)
1.02 (0.67, 1.56)
0.45 (0.22, 0.93)*
2.43 (1.26, 4.70)**
Concurrency
1.27 (1.04, 1.54)*
1.28 (1.07, 1.52)**
1.23 (0.94, 1.61)
1.20 (0.92, 1.57)
More than one main partner
0.76 (0.50, 1.16)
0.85 (0.51, 1.40)
1.16 (0.52, 2.58)
1.12 (0.55, 2.27)
HIV-positive
1.17 (0.80, 1.71)
0.97 (0.66, 1.41)
2.11 (1.13, 3.93)*
1.04 (0.53, 2.01)
P < 0.05,
Author Manuscript
**
P < 0.01,
***
P < 0.001
AIDS Behav. Author manuscript; available in PMC 2021 August 01.