Basal ganglia
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Most cited papers in Basal ganglia
Recognition that inflammation may represent a common mechanism of disease has been extended to include neuropsychiatric disorders including major depression. Patients with major depression have been found to exhibit increased peripheral... more
A consensus conference on multiple system atrophy (MSA) in 1998 established criteria for diagnosis that have been accepted widely. Since then, clinical, laboratory, neuropathologic, and imaging studies have advanced the field, requiring a... more
The traditional view that the basal ganglia and cerebellum are simply involved in the control of movement has been challenged in recent years. One of the pivotal reasons for this reappraisal has been new information about basal ganglia... more
A sensitive immunofluorescene technique was used to describe systematically the distribution of dopamine-β-hydroxylase (DBH)-containing cell bodies, non-terminal fiber pathways, and terminal fields in the brain of the male albino rat. DBH... more
The neostriatum is the largest component of the basal ganglia, and the main recipient of afferents to the basal ganglia from the cerebral cortex and thalamus. Studies of the cellular organization of the neostriatum have focused upon the... more
A selection problem arises whenever two or more competing systems seek simultaneous access to a restricted resource. Consideration of several selection architectures suggests there are significant advantages for systems which incorporate... more
Fiez. Tracking the hemodynamic responses to reward and punishment in the striatum. J Neurophysiol 84: 3072-3077, 2000. Research sug- gests that the basal ganglia complex is a major component of the neural circuitry that mediates... more
By homologous recombination of an internal ribosome entry site and Cre recombinase coding region into the 3'-untranslated region of the mouse Emx1 gene, we have generated a strain of mice, Emx1(IRES)cre, that expresses the Cre... more
The accuracy of PET for measuring regional radiotracer concentrations in the human brain is limited by the finite resolution capability of the scanner and the resulting partial volume effects (PVEs). We designed a new algorithm to correct... more
The anatomical correlates of extrapersonal visual neglect were investigated in 110 right-handed stroke patients with lesions confined to the right hemisphere. Neglect is much more frequently associated with retrorolandic damage, as... more
In normal rats dopamine-storing nerve terminals are found in the neostriatum (= the caudate nucleus + putamen) and dopamine-containing nerve cells in the substantia nigra, mainly in the pars compacta. After electrolytic lesions in the... more
Insight into the organization of the basal ganglia in the normal, parkinsonian and l-dopa-induced dyskinesia states is critical for the development of newer and more effective therapies for Parkinson's disease. We believe that the basal... more