Doxazosin
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Recent papers in Doxazosin
Abstract—Abnormal nocturnal blood pressure (BP) dipping status may,be partly determined,by nocturnal sympathetic activity. We studied the effect of nighttime dosing of an a1-adrenergic blocker, doxazosin, on the BP dipping status of 118... more
Doxazosin is an alpha-adrenergic antagonist that selectively inhibits the alpha-1 subtype commonly used to treat hypertension and benign prostatic hyperplasia. Determination of doxazosin levels in pharmaceutical preparations and... more
This review evaluates the role of α-adrenoceptor antagonists as a potential treatment of prostate cancer (PCa). Cochrane, Google Scholar and Pubmed were accessed to retrieve sixty-two articles for analysis. In vitro studies demonstrate... more
Twenty five Holstein-Friesian heifers, clinically normal and with regular oestrous cycles, were used for induction of superovulation (PMSG-PGF(2)alpha-Neutra-PMSG). Animals were divided into 5 groups receiving: I - detomidine (40... more
Herein we report on a young girl with recurrent, functioning paraganglioma of the organ of Zuckerkandl and severe and sustained arterial hypertension (systolic pressure >200, diastolic pressure >120 mmHg); with evidence of... more
Which drug lowers blood pressure (BP) best in patients with resistant hypertension? Spironolactone causes the largest BP reduction (10/4 mm Hg) for “fourth-line therapy” in resistant hypertension; an additional 1 in 3 patients will reach... more
This review evaluates the role of α-adrenoceptor antagonists as a potential treatment of prostate cancer (PCa). Cochrane, Google Scholar and Pubmed were accessed to retrieve sixty-two articles for analysis. In vitro studies demonstrate... more
The effect of doxazosin, a selective alpha-1 adrenergic inhibitor, on hemostasis was investigated in 9 cynomolgus monkeys. During 12 weeks of doxazosin treatment (1 mg/kg per day), serum lipids, lipoprotein cholesterols, blood... more
Apoptosis effect of oral alpha-blockers is known in the prostate. Apoptosis index of silodosin has not been proved, yet. Aims are to present apoptosis index of silodosin in prostate and to compare this with other currently used... more
This study was designed to systematically analyze and evaluate the effects of in vivo blockade of α1-adrenergic receptors (α1-ADRs) on the stress-induced disturbance of steroidogenic machinery in Leydig cells. Parameters followed 1)... more