Hystology
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Recent papers in Hystology
Preparat Histologi Kulit Tebal (Kulit Telapak Kaki)
By the end of the 19th century, the subject of internal secretion and the consequences of its perturbations had been explored in considerable depth but with little clear understanding. Despite the anatomic delineation of the majority of... more
By the end of the 19th century, the subject of internal secretion and the consequences of its perturbations had been explored in considerable depth but with little clear understanding. Despite the anatomic delineation of the majority of the glands and tissues that comprised the gross endocrine system, the cellular basis and the interactions between the ‘internal glands’ and the nervous system had not been clearly delineated. Prominent early investigators in the field included Rudolf Peter Heidenhain (1834–1897), who described a novel class of clear cells (1868), Paul Langerhans (1847–1888), who identified pancreatic islets in 1869, and M.C. Ciacco (1877–1956), who coined the term ‘enterochromaffin’ (1906). Their contributions facilitated the description of the diffuse neuroendocrine system (DNES) by F. Feyrter (1938) which allowed for the understanding of a syncytial regulatory system that consisted of both endocrine and neural components. This rich developmental history often reveals the name of Kulchitsky, but little recognition has been given to his seminal contributions. Indeed the Russian, Nikolai Konstantinovich Kulchitsky (1856–1925), both due to his modest and unassuming nature and the tragic events of his life, was little recognized and has been relegated to a mere eponymous attribution. In reality, his life bears legacy to rich scientific contributions spanning a great teaching and scientific career at Kharkov University, to responsibilities as the Imperial Minister of Education for all of Russia. He identified the Kulchitsky cell, trained and mentored numerous professors of histopathology, was incarcerated by the Bolsheviks and worked in a soap factory to save his life. He and his family finally fled on a British battleship with the remnants of the Russian Royal family to England where he secured a position with Bayliss and Starling at University College, London (UCL). His mysterious demise in a lift-shaft accident on his 69th birthday tragically terminated a life of great service to science and teaching. He excelled as a histopathologist and was responsible for the early description of tonsillar and gut epithelial leucocytes as well as defining components of the Ascaris life cycle. At UCL, his contributions to the anatomic delineation of muscle nerve endings were highly regarded and widely admired. It is, however, his identification of the enterochromaffin cell in 1897 for which he is most remembered since this observation formed the basis for the subsequent delineation of the DNES and provided the cellular framework on which the discipline of gut neuroendocrinology would be established.
- by Mark Kidd and +1
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- History of Medicine, Russian Politics, Histology, Russian History
ABSTRAK Salah satu penyakit yang sering menyerang ayam adalah Newcastle Disease (ND) dan merupakan penyakit yang sangat menular dengan angka kematian yang tinggi, disebabkan oleh virus genus paramyxovirus dengan famili paramyxoviridae.... more
ABSTRAK Salah satu penyakit yang sering menyerang ayam adalah Newcastle Disease (ND) dan merupakan penyakit yang sangat menular dengan angka kematian yang tinggi, disebabkan oleh virus genus paramyxovirus dengan famili paramyxoviridae. Nama lain untuk ND adalah tetelo, pseudovogolpest, sampar ayam, rhaniket, pneumoencephalitis dan tontaor furrens. Penyakit ini merupakan salah satu penyakit penting pada ayam. Melihat tingkat keganasan penyakit dan kematian tinggi pada ayam, maka dirasa perlu dilakukan penelitian untuk mengetahui tingkat infeksi, gambaran patologi anatomis dan histopatologis ND. Sampel penelitian yang digunakan adalah ayam yang menderita dan/atau menampakkan gejala-gejala penyakit sebanyak 90 ekor yang berasal dari setiap nekropsi/bedah bangkai dan diperiksa perubahan patologi anatomis dan pemeriksaan histopatologis. Secara keseluruhan tingkat infeksi ND pada ayam kampung yang diseksi di Laboratorium FKH Unsyiah tinggi seperti halnya dengan kasus-kasus ND pada umumnya dengan angka infeksi 86,7 %. Perubahan pascamati/patologi anatomis pada pada ayam yang terserang penyakit ND pada penelitian ini serupa dengan kasus-kasus ND secara umum, meliputi peradangan yang terjadi pada saluran pencernaan dan saluran pernafasan. Perubahan histopatologis/mikroskopik meliputi hiperemi, hemoragi, dan nekrosis pada proventrikulus, usus, seka tonsil, paru, otak, hati yang merupakan gambaran patognomonik ND. Dari hasil penelitian ini dapat disimpulkan tingginya tingkat infeksi ND pada ayam sangat berhubungan dengan galur virus, rute infeksi, faktor lingkungan, cara pemeliharaan, ataupun infeksi campuran dengan mikroorganisme lainnya.
Kata kunci: Ayam kampung, Newcastle Disease (ND), patologi anatomis, histopatologis
ABSRACT Newcastle disease (ND) is a disease that often attacks chickens and a highly infectious disease with high mortality rates. ND was caused by a virus of the genus paramyxovirus and family paramyxoviridae. Other name of ND was tetelo, pseudovogolpest, chicken plaque, rhaniket, pneumoencephalitis, and tontaor furrens. This disease is one of the important diseases in poultry. Due to the contagiousness level and high mortality rate of the disease, this research was carried out in order to examine the contagious level, anatomical pathology, and hystopathological changes of ND. The samples used in this research were ND infected chicken or clinically shown the symptoms of the disease as much as 90 chickens dissected and examined the anatomical pathology and hystopathology. The infection rate of ND on native chicken dissected at Pathology Laboratory, Veterinary Medicine Faculty, Syiah Kuala University was as high as other general cases with the number of 86.7%. Post mortum examination of ND infected chicken in this study similar to other ND cases was inflammation of the digestive and respiratory tract, whereas hyperemia, edema, hemorrhage, and necrosis of the proventricullus which is an ND pathognomonic symptom were observed as histopathological changes. From the result of this study it can be concluded that the high rates of ND infection on native chicken was closely related to virus strain, infection route, environmental factors, maintenance, and cross infection with other microorganisms.
Key words: Native chicken, Newcastle Disease (ND), anatomical pathology, hystopathology
Kata kunci: Ayam kampung, Newcastle Disease (ND), patologi anatomis, histopatologis
ABSRACT Newcastle disease (ND) is a disease that often attacks chickens and a highly infectious disease with high mortality rates. ND was caused by a virus of the genus paramyxovirus and family paramyxoviridae. Other name of ND was tetelo, pseudovogolpest, chicken plaque, rhaniket, pneumoencephalitis, and tontaor furrens. This disease is one of the important diseases in poultry. Due to the contagiousness level and high mortality rate of the disease, this research was carried out in order to examine the contagious level, anatomical pathology, and hystopathological changes of ND. The samples used in this research were ND infected chicken or clinically shown the symptoms of the disease as much as 90 chickens dissected and examined the anatomical pathology and hystopathology. The infection rate of ND on native chicken dissected at Pathology Laboratory, Veterinary Medicine Faculty, Syiah Kuala University was as high as other general cases with the number of 86.7%. Post mortum examination of ND infected chicken in this study similar to other ND cases was inflammation of the digestive and respiratory tract, whereas hyperemia, edema, hemorrhage, and necrosis of the proventricullus which is an ND pathognomonic symptom were observed as histopathological changes. From the result of this study it can be concluded that the high rates of ND infection on native chicken was closely related to virus strain, infection route, environmental factors, maintenance, and cross infection with other microorganisms.
Key words: Native chicken, Newcastle Disease (ND), anatomical pathology, hystopathology
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