NC

Steps in the replication of human immunodeficiency virus type 1 (HIV-1) occurring in the virus but not in the host are preferred targets of antiretroviral therapy. Strand transfer is unique; the DNA strand being made by viral reverse transcriptase (RT) is moved from one RNA template position to another. Understanding the mechanism requires knowing whether the RT directly mediates the template exchange or dissociates during the exchange, so that it occurs by polymer dynamics. Earlier work in vitro showed that the presence of an RT-trapping polymer would allow synthesis on the original or donor template but completely block transfer and subsequent synthesis on the second or acceptor template. One interpretation is that the RT must dissociate during transfer, but an alternative is that sequestration of non-polymerizing RTs prevents polymerization-independent ribonuclease H (RNase H) cleavages of the donor template necessary for strand exchange. To resolve this ambiguity, we designed a ...

The aim of this paper is to prove the validity of an alternative prediction technique to another classical one, which is Box-Jenkins methodology, in order to produce multivariate prediction. In particular, one-step ahead forecasts will be obtained for two time series: thermic and hydraulic power production. These forecasts are based on the past values of those series.

This project began by noticing that congregations have grown weary of preaching, and the only explanation they have for this problem is a methodological failure on the part of the preacher. Many members of our congregations do not realize that they are part of the preaching experience and can improve their experience by listening well. The problem is complicated by their lack of a theology of preaching. Further, the congregation has no resources available to correct the problem. The congregation shapes the preaching that it receives over time; therefore, for the theology of preaching to be corrected, it must be corrected for the members of the congregation. The Biblical-Theological Rationale of this project begins by discussing the theology of words. Afterward, several New Testament words translated as "preaching" are discussed, followed by an exegesis of two Pauline passages: Romans 10: 14-21 and 1 Corinthians 1: 17-2:5. The project then explores the role of the Holy Spirit in preaching; insisting that preaching is a means of grace. The project uses a sample group from Samaria Baptist Church in Raleigh, NC and pre-tests their existing thinking about preaching. The sample was then divided into a focus group and a control group. The focus group attended a series of Bible studies about preaching. The teaching methods were lecture and discussion. The Bible studies lasted about one hour each. Following the Bible studies both were groups post-tested. There was a follow-up conversation with the focus group as well as interviews with two members of the focus group to detect bias. This project used both quantitative and qualitative analysis. The focus group participants were able to increase their scores significantly from pre-test to post-test. Furthermore, the focus group participants demonstrated their competency during the follow-up conversation by declaring their improved ability to listen to preaching in the follow-up conversation. For future research, a larger focus group could be drawn and taught the same information. Afterward, they could be tested immediately following the completion of the teaching process. Several months later, the effectiveness of listening to preaching over time could be determined.

Embedding maximum information in a stego-image with minimum change in its appearance has been a major concern in image-based steganography techniques. In this paper, utilizing Genetic algorithm (GA) we have built up a competent optimal robust steganography technique. The watermarks are implanted into the HL and LH frequency coefficients in bi-orthogonal wavelet transform (BWT). In order to get better the quality of stego image and robustness of the steganography we have to develop an optimization technique using a model to explore for the optimal locations. We examine the presentation of the suggested technique in terms of Peak signal to Noise ratio (PSNR) and Normalized correlation (NC). The proposed technique is the application of steganography for confidential transmission of symmetric key generated using Genetic algorithm (GA) that can accomplish a good imperceptibility and robustness of the image