Cigarette smoking is currently the leading cause of preventable deaths and disability throughout the world, being responsible for about five million premature deaths/year. Unfortunately, fewer than 10% of tobacco users who try to stop... more
Cigarette smoking is currently the leading cause of preventable deaths and disability throughout the world, being responsible for about five million premature deaths/year. Unfortunately, fewer than 10% of tobacco users who try to stop smoking actually manage to do so. The main addictive agent delivered by cigarette smoke is nicotine, which induces psychostimulation and reward, and reduces stress and anxiety. The use of new technologies (including optogenetics) and the development of mouse models characterised by cell-specific deletions of receptor subtype genes or the expression of gain-of-function nAChR subunits has greatly increased our understanding of the molecular mechanisms and neural substrates of nicotine addiction first revealed by classic electrophysiological, neurochemical and behavioural approaches. It is now becoming clear that various aspects of nicotine dependence are mediated by close interactions of the glutamatergic, dopaminergic and γ-aminobutyric acidergic system...
— Hypervisor virtualization that uses bare metal architecture allows to allocate and provide resources for each created virtual machines. Resources such as: CPU and memory, can be added or upgraded anytime to the host hardware... more
— Hypervisor virtualization that uses bare metal architecture allows to allocate and provide resources for each created virtual machines. Resources such as: CPU and memory, can be added or upgraded anytime to the host hardware (virtualization server) to be able to create more virtual machines. However, upgrading the hard drive size cannot be done anytime if there are already have data or virtual machine that has fully operated on the host hardware, related to the raid system and the establishment of hard drive partition. Upgrading hard drive size on virtualization server can be done by using NFS protocol on NAS server. VSphere ESXi able to use NFS protocol and store the virtual disk that is used by virtual machine as guest operating system on network storage besides using local hard drive (host hardware hard drive). When the virtual machine want to run the guest operating system, it will request to write/read virtual disk there is stored on NAS by using NFS protocol through the network. In this research, measurements has been taken on data communication performance due the usage of NFS as virtual machine's datastore in addition to local hard drive usage on server's device. Measurements were performed by sending various data size from client to server (virtual machine) and measure write/read speed on server's cache memory and hard drive, and measure RTT (Round-trip Time) delay between client-server. The testing has been conducted on virtual machines that use local drive and NFS as virtual disk datastore.
Cigarette smoking is currently the leading cause of preventable deaths and disability throughout the world, being responsible for about five million premature deaths/year. Unfortunately, fewer than 10% of tobacco users who try to stop... more
Cigarette smoking is currently the leading cause of preventable deaths and disability throughout the world, being responsible for about five million premature deaths/year. Unfortunately, fewer than 10% of tobacco users who try to stop smoking actually manage to do so. The main addictive agent delivered by cigarette smoke is nicotine, which induces psychostimulation and reward, and reduces stress and anxiety. The use of new technologies (including optogenetics) and the development of mouse models characterised by cell-specific deletions of receptor subtype genes or the expression of gain-of-function nAChR subunits has greatly increased our understanding of the molecular mechanisms and neural substrates of nicotine addiction first revealed by classic electrophysiological, neurochemical and behavioural approaches. It is now becoming clear that various aspects of nicotine dependence are mediated by close interactions of the glutamatergic, dopaminergic and γ-aminobutyric acidergic system...
Cigarette smoking is currently the leading cause of preventable deaths and disability throughout the world, being responsible for about five million premature deaths/year. Unfortunately, fewer than 10% of tobacco users who try to stop... more
Cigarette smoking is currently the leading cause of preventable deaths and disability throughout the world, being responsible for about five million premature deaths/year. Unfortunately, fewer than 10% of tobacco users who try to stop smoking actually manage to do so. The main addictive agent delivered by cigarette smoke is nicotine, which induces psychostimulation and reward, and reduces stress and anxiety. The use of new technologies (including optogenetics) and the development of mouse models characterised by cell-specific deletions of receptor subtype genes or the expression of gain-of-function nAChR subunits has greatly increased our understanding of the molecular mechanisms and neural substrates of nicotine addiction first revealed by classic electrophysiological, neurochemical and behavioural approaches. It is now becoming clear that various aspects of nicotine dependence are mediated by close interactions of the glutamatergic, dopaminergic and γ-aminobutyric acidergic system...
The Cloud and Big Data movements triggered a move to more centralized, remote storage resources. However, the use of such remote resources raises a number of challenges at the protocol level. In this paper, we first evaluate the influence... more
The Cloud and Big Data movements triggered a move to more centralized, remote storage resources. However, the use of such remote resources raises a number of challenges at the protocol level. In this paper, we first evaluate the influence of several factors, including network latency, on the performance of the NFS protocol. Then, we explore how statistical methods such as a fractional factorial design of experiments could have helped to drastically reduce the number of required experiments while still providing a similar amount of information about the impact of the factors.
Persona-sized HPC clusters are widely used in many small labs, because they are cost-effective and easy to build. Instead of adding costly new nodes to old clusters, we may try to make use of some servers’ idle times by including them... more
Persona-sized HPC clusters are widely used in many small labs, because they are cost-effective and easy to build. Instead of adding costly new nodes to old clusters, we may try to make use of some servers’ idle times by including them working independently on the same LAN, especially during the night. However such extension across a firewall raises not only some security problem with NFS but also a load balancing problem caused by heterogeneity. In this paper, we propose a method to solve such problems using only old techniques applicable to old systems as is, without requiring any upgrade for hardware or software. Some experimental results dealing with heterogeneity and load balancing are presented using a two-queue overflow queuing network problem.
