Neuronal Development
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Recent papers in Neuronal Development
Brain-derived neurotrophic factor (BDNF) is important in supporting neuronal development. BDNF imbalance due to excessive neuronal inhibition can result in the apoptotic degeneration of developing neurons. Since general anesthetics cause... more
SYNAPTIC transmission mediated by the N-methyl-D-aspartate (NMDA) glutamate receptor plays a key role in a range of plastic processes in the nervous system. These include long-term potentiation of synaptic transmission mediated by the... more
In this study TSGA10 has been demonstrated as a testis-specific human gene that encodes a protein localized in sperm-tail and conserved in ciliary structure. Further investigations showed TSGA10 signalling and expression during... more
While neuronal activity is important in CNS development, little is known of the behaviour of the actual neurotransmitters released during this period. None the less, indirect evidence has suggested that the neurotransmitter dopamine... more
The use of mice with targeted gene deletions (knockouts [KOs]) provides an important tool to investigate the mechanisms underlying behavior, neuronal development, and the sequella of neuropsychiatric diseases. MRI has been used to image... more
... Review. Nature Reviews Neuroscience 3, 791-802 (October 2002) | doi :10.1038/nrn940. Protein palmitoylation: a regulator of neuronal development and function. Alaa El-Din El-Husseini 1 & David S. Bredt 2 About the authors.... more
The clinical manifestation of most diseases of the central nervous system results from neuronal dysfunction or loss. Diseases such as stroke, epilepsy and neurodegeneration (e.g.... more
SCG10 (Superior Cervical Ganglia 10, STMN2) is a member of the stathmin family of proteins. Stathmins regulate microtubule dynamics by inhibiting polymerization and promoting their depolymerization. SCG10 is believed to be a... more
Monoamine oxidase (MAO) regulates levels of dopamine, serotonin, and noradrenaline in the nervous tissue and is required for proper neuronal development. The purpose of this study was to determine if oral exposure of adult female rats to... more
Muscarinic (mAChRs) and nicotinic acetylcholine receptors (nAChRs) are involved in various physiological processes, including neuronal development. We provide evidence for expression of functional nicotinic and muscarinic receptors during... more
Parkinson's disease (PD) is a progressive neurodegenerative disease with typical motor symptoms due to the... more
The cell adhesion molecules NCAM and L1 are considered to play key roles in neuronal development and plasticity. L1 has been shown to interact with NCAM, possibly through NCAM binding to oligomannosidic glycans present in L1. We... more
This hypothesis throws up two critical predictions whose veracity is left to better-positioned researchers to determine. These are: That cone photoreceptors are associated with Norepinephrine is a prediction; whoever can, must check if... more
Final morphological polarization of neurons, with the development of a distinct axon and of several dendrites, is preceded by phases of non-polarized architecture. The earliest of these phases is that of the round neuron arising from the... more