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KEGG   NETWORK: N01836
Entry
N01836                      Network                                
Name
Microtubule plus end regulation network
Definition
(TUBA+TUBB) == MAPRE1,MAPRE3 == SxlPs,TOGs,CAP-Glys
  Expanded
((7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688)) == 22919,22924 == (324,10297,23499,667),(9793,23332,23122),(6249,7461,1639)
Class
nt06541 Cytoskeleton in neurons
Type
Reference
Gene
7846  TUBA1A; tubulin alpha 1a
10376  TUBA1B; tubulin alpha 1b
84790  TUBA1C; tubulin alpha 1c
7278  TUBA3C; tubulin alpha 3c
113457  TUBA3D; tubulin alpha 3d
112714  TUBA3E; tubulin alpha 3e
7277  TUBA4A; tubulin alpha 4a
51807  TUBA8; tubulin alpha 8
203068  TUBB; tubulin beta class I
81027  TUBB1; tubulin beta 1 class VI
7280  TUBB2A; tubulin beta 2A class IIa
347733  TUBB2B; tubulin beta 2B class IIb
10381  TUBB3; tubulin beta 3 class III
10382  TUBB4A; tubulin beta 4A class IVa
10383  TUBB4B; tubulin beta 4B class IVb
84617  TUBB6; tubulin beta 6 class V
347688  TUBB8; tubulin beta 8 class VIII
22919  MAPRE1; microtubule associated protein RP/EB family member 1
22924  MAPRE3; microtubule associated protein RP/EB family member 3
324  APC; APC regulator of WNT signaling pathway
10297  APC2; APC regulator of WNT signaling pathway 2
23499  MACF1; microtubule actin crosslinking factor 1
667  DST; dystonin
9793  CKAP5; cytoskeleton associated protein 5
23332  CLASP1; cytoplasmic linker associated protein 1
23122  CLASP2; cytoplasmic linker associated protein 2
6249  CLIP1; CAP-Gly domain containing linker protein 1
7461  CLIP2; CAP-Gly domain containing linker protein 2
1639  DCTN1; dynactin subunit 1
Reference
PMID:20930136
  Authors
Akhmanova A, Steinmetz MO
  Title
Microtubule +TIPs at a glance.
  Journal
J Cell Sci 123:3415-9 (2010)
DOI:10.1242/jcs.062414
Reference
PMID:27530065
  Authors
Voelzmann A, Hahn I, Pearce SP, Sanchez-Soriano N, Prokop A
  Title
A conceptual view at microtubule plus end dynamics in neuronal axons.
  Journal
Brain Res Bull 126:226-237 (2016)
DOI:10.1016/j.brainresbull.2016.08.006
Reference
PMID:26562752
  Authors
Akhmanova A, Steinmetz MO
  Title
Control of microtubule organization and dynamics: two ends in the limelight.
  Journal
Nat Rev Mol Cell Biol 16:711-26 (2015)
DOI:10.1038/nrm4084
Reference
PMID:24943963
  Authors
Gupta KK, Alberico EO, Nathke IS, Goodson HV
  Title
Promoting microtubule assembly: A hypothesis for the functional significance of the +TIP network.
  Journal
Bioessays 36:818-26 (2014)
DOI:10.1002/bies.201400029
Reference
PMID:18322465
  Authors
Akhmanova A, Steinmetz MO
  Title
Tracking the ends: a dynamic protein network controls the fate of microtubule tips.
  Journal
Nat Rev Mol Cell Biol 9:309-22 (2008)
DOI:10.1038/nrm2369
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