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Name of Drug

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Name of Drug Mechanisms of Action Indications/Containdications Adverse Reactions Nursing Considerations

Indications: Celecoxib is licensed *Administer drug with food


Generic: Celecoxib Analgesic and anti- Adverse effects
for use or after meals if GI upset
inflammatory activities in osteoarthritis, rheumatoid CNS: Headache, dizziness,
related to inhibition of the arthritis, acute pain, occurs.
painful menstruation and somnolence, insomnia, fatigue,
COX-2 enzyme, menstrual symptoms, ankylosing
*Establish safety measures
Brand Name: tiredness, dizziness,
 Celebrex which is activated in spondylitis and to reduce the if CNS, visual disturbances
inflammation to cause the number of colon and rectal polyps tinnitus, ophthamologic effects
 Celebra occur.
in patients with familial
signs and symptoms Dermatologic:Rash, pruritus,
adenomatous polyposis. It was *Arrange for periodic
associated with originally intended to relieve pain sweating, dry mucous
Available forms ophthalmologic examination
inflammation; does not while minimizing the
Capsules—100, 200 mg gastrointestinal adverse effects membranes, stomatitis
affect the COX-1 enzyme, during long-term therapy.
usually seen with GI: Nausea, abdominal
which protects the lining of conventional NSAIDs. *If overdose occurs,
the GI pain,dyspepsia, flatulence, GI
Contraindications: institute emergency
tract and has blood clotting bleed
Contraindicated with allergies to procedures—gastric lavage,
and renal functions. Hematologic: Neutropenia,
sulfonamides, celecoxib, NSAIDs, induction of
eosinophilia, leukopenia,
or aspirin; emesis, supportive therapy.
pancytopenia,
significant renal impairment; *Provide further comfort
thrombocytopenia,
pregnancy; lactation. measures to reduce pain (eg
agranulocytosis,
positioning, environmental
granulocytopenia, aplastic
Use cautiously with impaired control), and to reduce
anemia, decreased
hearing, hepatic and inflammation (eg warmth,
hemoglobin or hematocrit,
cardiovascular conditions positioning, rest
bone marrow depression,
Name of Drug Mechanisms of Action Indications/Containdications Adverse Reactions Nursing Considerations

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