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    Generic Name: Mebeverine Hydrochloride Mechanism of Action Side Effects/ Adverse Reaction Nursing Responsibility Assessment & Drug Effects

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    Niziu Bears
    Mebeverine hydrochloride is an antispasmodic agent used to treat irritable bowel syndrome and other conditions involving painful stomach cramps. It works by exerting a direct action on the gastrointestinal smooth muscle without affecting normal gut motility. Common side effects include dizziness, headache, indigestion, constipation, and loss of appetite. Nurses are responsible for monitoring patients for signs of ischemic colitis and decreasing the dose or stopping the drug if side effects occur. Patients should discontinue use if abdominal pain or bloody diarrhea develops.

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    Generic Name: Mebeverine Hydrochloride Mechanism of Action Side Effects/ Adverse Reaction Nursing Responsibility Assessment & Drug Effects

    Uploaded by

    Niziu Bears
    184 views4 pages
    Mebeverine hydrochloride is an antispasmodic agent used to treat irritable bowel syndrome and other conditions involving painful stomach cramps. It works by exerting a direct action on the gastrointestinal smooth muscle without affecting normal gut motility. Common side effects include dizziness, headache, indigestion, constipation, and loss of appetite. Nurses are responsible for monitoring patients for signs of ischemic colitis and decreasing the dose or stopping the drug if side effects occur. Patients should discontinue use if abdominal pain or bloody diarrhea develops.

    Original Description:

    drug study

    Original Title

    Mebeverine DS

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    Mebeverine hydrochloride is an antispasmodic agent used to treat irritable bowel syndrome and other conditions involving painful stomach cramps. It works by exerting a direct action on the gastrointestinal smooth muscle without affecting normal gut motility. Common side effects include dizziness, headache, indigestion, constipation, and loss of appetite. Nurses are responsible for monitoring patients for signs of ischemic colitis and decreasing the dose or stopping the drug if side effects occur. Patients should discontinue use if abdominal pain or bloody diarrhea develops.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    184 views4 pages

    Generic Name: Mebeverine Hydrochloride Mechanism of Action Side Effects/ Adverse Reaction Nursing Responsibility Assessment & Drug Effects

    Uploaded by

    Niziu Bears
    Mebeverine hydrochloride is an antispasmodic agent used to treat irritable bowel syndrome and other conditions involving painful stomach cramps. It works by exerting a direct action on the gastrointestinal smooth muscle without affecting normal gut motility. Common side effects include dizziness, headache, indigestion, constipation, and loss of appetite. Nurses are responsible for monitoring patients for signs of ischemic colitis and decreasing the dose or stopping the drug if side effects occur. Patients should discontinue use if abdominal pain or bloody diarrhea develops.

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    © All Rights Reserved
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    Download as docx, pdf, or txt
    of 4

    GENERIC NAME: MECHANISM OF ACTION SIDE EFFECTS/ ADVERSE NURSING

    REACTION
    MEBEVERINE RESPONSIBILITY
    Mebeverine is an antispasmodic
    HYDROCHLORIDE agent which exerts direct action on
    the GI smooth muscle w/o affecting CNS: Dizziness, headache, insomnia Assessment & Drug Effects
    normal gut motility. The exact
    mechanism is unknown, but multiple -Monitor for and report immediately
    GI: Indigestion, constipation, loss of
    mechanisms might contribute to its
    signs of ischemic colitis such as new
    local effect in the GI tract, e.g. a appetite
    decrease in ion channel or worsening abdominal pain, bloody
    permeabilities, blockade of diarrhea, or blood in the stool.
    norepinephrine reuptake, a local CV: heartburn, decreased pulse rate
    anesthetic effect, changes in water
    -Withhold drug and notify physician
    absorption.
    Skin: rash, urticaria, angioedema
    if patient has not had adequate
    BRAND NAME: INDICATION control of IBS symptoms after
    Colofac treatment.
    Mebeverine hydrochloride is a type
    of medicine known as an
    DRUG ILLUSTRATION: -Monitor carefully patients who have
    antispasmodic. It helps with muscle
    decreased GI motility (e.g., older
    spasms. It can be used to ease painful
    adults, persons receiving other drugs
    stomach cramps if you have irritable
    which may decrease GI motility) as
    bowel syndrome (IBS) or other
    they may be at greater risk of serious
    conditions. 
    complications of constipation.

    -Carefully monitor patients with any


    degree of hepatic insufficiency as
    they may be more susceptible to
    adverse drug effects.

    -Monitor periodically for cardiac


    arrythmias, especially with
    preexisting cardiovascular disease.
    CLASSIFICATION: CONTRAINDICATION
    anticholinergics, antispasmodics Contraindicated to paralytic ileus and
    Used in the treatment of hypersensitivity to anticholinergics.
    functional bowel disorders. Patient & Family Education

    DOSAGE/ FREQUENCY/
    ROUTE: -Read the Medication Guide before
    starting Colofac.
    50mg/15 ml P.O. 3 times a day

    -Discontinue Colofac immediately


    and contact your physician if you
    experience any of the following:
    constipation, new or worsening
    abdominal pain, bloody diarrhea, or
    blood in the stool.
    if stomach cramps does not resolve
    after discontinuation of Colofac.
    Resume colofac again only if
    stomach cramps has resolved and
    your physician directs you to begin
    taking the medication again.

    -Stop taking Colofac and contact


    your physician if IBS symptoms are
    not adequately controlled after 2 wk
    of medication.

    -Do not breast feed while taking this


    drug without consulting physician.

    Reference/s: Nurses’ Drug Guide (Wilson B, Shannon M, Stang, C. 2004)

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