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INDOMETHACIN

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Drug name General details

INDOMETHACIN
Drug class NSAID COX inhibitor Trade names Artracin, Flexin, Imbrilon, Indoflex, Indoloar, Indomax, Indomod, Mobilan, Rheumacin, Rimacid Availability OTC 5 - 10 hours

Indomethacin is an NSAID, first introduced in the early 1960s and can have serious side effects. It is used for inflammatory conditions including, rheumatoid and osteoarthritis, ankylosing spondylosis, gout, bursitis and tendonitis. It is more potent than ibuprofen or aspirin and only needs to be taken twice daily. It has more side effects, including gastric irritation and bleeding.

How taken Capsules Liquid Suppositories Injection Side effects Symptom Nausea/vomiting Gastric pain Diarrhoea Indigestion Dizziness Headache Wheezing Rash Blurred vision Depression Other drug interactions

Dosage 50 - 200 mg/ day

Duration of action

considerations Occurrence Common Common Common Common Common Common Rare Rare Rare Rare Patients may have skin reactions to NSAIDs, such as rashes. This will make treating the patient difficult. Mobilisation techniques would be better suited if the patient is taking anticoagulents in conjunction with Indomethacin. Dietary advice No specific dietary advice Special precautions Patients taking anti-coagulant drugs should be advised not to take this drug as it may increase the anti-coagulant effect.

Interactions with drugs including anticoagulants and corticosteroids. Increased risk of bleeding, bruising and the development of gastric ulcers.

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