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    Dextromethorphan Hydrobromide

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    Dextromethorphan hydrobromide is a nonopioid antitussive that controls cough spasms by depressing the cough center in the medulla without analgesic or addictive properties. It is indicated for the control of nonproductive cough and is available in various oral forms including capsules, lozenges, liquids, and syrups. Common dosages are 10-30mg every 4-8 hours for adults and 6-12mg every 1-4 hours for children 6-12 years old. Dextromethorphan has the potential for respiratory depression in overdose and should not be used if the cough persists for over a week or is accompanied by other symptoms.

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    Dextromethorphan Hydrobromide

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    api-3797941
    1K views2 pages
    Dextromethorphan hydrobromide is a nonopioid antitussive that controls cough spasms by depressing the cough center in the medulla without analgesic or addictive properties. It is indicated for the control of nonproductive cough and is available in various oral forms including capsules, lozenges, liquids, and syrups. Common dosages are 10-30mg every 4-8 hours for adults and 6-12mg every 1-4 hours for children 6-12 years old. Dextromethorphan has the potential for respiratory depression in overdose and should not be used if the cough persists for over a week or is accompanied by other symptoms.

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    Dextromethorphan hydrobromide is a nonopioid antitussive that controls cough spasms by depressing the cough center in the medulla without analgesic or addictive properties. It is indicated for the control of nonproductive cough and is available in various oral forms including capsules, lozenges, liquids, and syrups. Common dosages are 10-30mg every 4-8 hours for adults and 6-12mg every 1-4 hours for children 6-12 years old. Dextromethorphan has the potential for respiratory depression in overdose and should not be used if the cough persists for over a week or is accompanied by other symptoms.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    1K views2 pages

    Dextromethorphan Hydrobromide

    Uploaded by

    api-3797941
    Dextromethorphan hydrobromide is a nonopioid antitussive that controls cough spasms by depressing the cough center in the medulla without analgesic or addictive properties. It is indicated for the control of nonproductive cough and is available in various oral forms including capsules, lozenges, liquids, and syrups. Common dosages are 10-30mg every 4-8 hours for adults and 6-12mg every 1-4 hours for children 6-12 years old. Dextromethorphan has the potential for respiratory depression in overdose and should not be used if the cough persists for over a week or is accompanied by other symptoms.

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    dextromethorphan hydrobromide

    (dex troe meth or' fan)


    Balminil DM (CAN), Benylin Adult, Benylin Pediatric, Creo-Terpin, Delsym,
    DexAlone, Hold DM, Koffex (CAN), Novahistex DM (CAN), Novahistine DM
    (CAN), Robitussin Pediatric (CAN), Trocal, Vicks Dry Hacking Cough

    Pregnancy Category C

    Drug class
    Nonopioid antitussive

    Therapeutic actions
    Lacks analgesic and addictive properties; controls cough spasms by depressing the cough
    center in the medulla; analog of codeine.

    Indication
    • Control of nonproductive cough

    Contraindications and cautions


    • Hypersensitivity to any component (check label of products for flavorings,
    vehicles); sensitivity to bromides; cough that persists for more than 1 wk, tends to
    recur, is accompanied by excessive secretions, high fever, rash, nausea, vomiting,
    or persistent headache (dextromethorphan should not be used; patient should
    consult a physician); lactation, pregnancy.

    Available forms
    Capsules—30 mg; lozenges—5, 7.5 mg; liquid—7.5 mg/5 mL; 10 mg/15 mL,
    15 mg/5 mL, 30 mg/5 mL; syrup—7.5 mg/5 mL, 10 mg/5 mL; sustained action liquid—
    30 mg/5 mL

    Dosages
    ADULTS AND PATIENTS > 12 YR
    Lozenges, syrup, and chewy squares
    10–30 mg q 4–8 hr PO. Do not exceed 120 mg/24 hr.
    Sustained-action liquid
    60 mg bid PO up to 120 mg/day.
    PEDIATRIC PATIENTS
    Lozenges, syrup, and chewy squares
    6–12 yr: 5–10 mg q 1–4 hr PO. Do not exceed 60 mg/24 hr.
    Sustained-action liquid
    30 mg bid PO.
    Syrup and chewy squares
    2–6 yr: 7.5 mg q 6–8 hr PO. Do not exceed 30 mg/24 hr. Do not give lozenges to this age
    group.
    Sustained-action liquid
    15 mg bid PO up to 30 mg/day.
    < 2 yr: Use only as directed by a physician.
    Pharmacokinetics
    Route Onset Peak Duration
    Oral 15–30 min 2 hr 3–6 hr

    Metabolism: Hepatic; T1/2: 2–4 hr


    Distribution: Crosses placenta; enters breast milk
    Excretion: Urine

    Adverse effects
    • Respiratory: Respiratory depression (with overdose)

    Interactions
    Drug-drug
    • Concomitant MAOI use may cause hypotension, fever, nausea, myoclonic jerks
    and coma; avoid this combination

    Nursing considerations
    Assessment
    • History: Hypersensitivity to any component; sensitivity to bromides; cough that
    persists for more than 1 wk or is accompanied by excessive secretions, high fever,
    rash, nausea, vomiting, or persistent headache; lactation, pregnancy
    • Physical: T; R, adventitious sounds

    Interventions
    • Ensure drug is used only as recommended. Coughs may be symptomatic of a
    serious underlying disorder that should be diagnosed and properly treated; drug
    may mask symptoms of serious disease.

    Teaching points
    • Take this drug exactly as prescribed. Do not take more than or for longer than
    recommended.
    • Report continued or recurring cough, cough accompanied by fever, rash,
    persistent headache, nausea, vomiting.

    Adverse effects in Italic are most common; those in Bold are life-threatening.

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