University of San Carlos

College of Nursing
Cebu City

DRUG STUDY

Name of Patient:_ ____________ _____ Patient’s Health Profile: ________________________________________

Age: _ ________ Sex: _ _______ _ _______________________________.__________
Occupation: _______ Initial Complaint: _____________________________________________
Date of Admission:___ ___________ ___
Status: _________ _ Religion: ___________ _ Diagnosis: _____________________ _____________________________

Name of Drug Indications Adverse

Mechanism of Nursing
Generic name Classification Contraindications Route and Effects/Side
Action Responsibilities
Brand name Dosage Effects
Magnesium Chemical: Cation, Magnesium sulfate is Hypersensitivity to >To prevent and CNS: Confusion, ● Be aware that
Sulfate electrolyte believed to reduce magnesium salts or control seizures in decreased reflexes, magnesium sulfate is
Therapeutic: acetylcholine any component of preeclampsia or dizziness, syncope the elemental form of
Antacid, released by nerve magnesium- eclampsia as well CV: Arrhythmias, magnesium. Oral
antiarrhythmic, impulses, resulting in containing as seizures Hypotension preparations aren’t all
anti-convulsant, anticonvulsant preparations caused by GI: Flatulence, equivalent.
electrolyte effects and central epilepsy, vomiting ● Be aware that drug
replacement, nervous system Heart block, MI, glomerulonephritis MS: Muscle cramps isn’t metabolized.
laxative depression and preeclampsia 2 hours , or RESP: Dyspnea, Drug remaining in the
Pregnancy blocking peripheral or less before hypothyroidism respiratory GI tract produces
category: A neuromuscular delivery depression or watery stool within 30
transmission. IV infusion or paralysis minutes to 3 hours.
Because magnesium injection SKIN: Diaphoresis ● Observe for and
antagonizes calcium Adults. Loading 4g Other: Allergic report to prescriber
and blocks calcium diluted in 250 mL reaction, early signs of
channels in bronchial of compatible hypermagnesemia, hypermagnesemia:
and vascular smooth solution and injection site pain or diplopia, bradycardia,
muscle, it also has infused over 30 irritation (I.M. form), depressed deep
antihypertensive minutes. laxative tendon reflexes,
 University of San Carlos
College of Nursing
Cebu City

actions. Maintenance: 1 to dependence, dyspnea, flushing,

2 g/hr by magnesium toxicity hypotension, nausea,
continuous slurred speech,
infusion. vomiting, and
weakness.
IM injection ● Be aware that
Adults – 4 to 5 q 4 magnesium may
hr, p.r.n. precipitate
Children – 20 to myasthenic crisis by
40 mg/kg, decreasing patient’s
repeated p.r.n. sensitivity to
acetylcholine.
● Frequently assess
cardiac status of
patient taking drugs
that lower heart rate,
such as beta
blockers, because
magnesium may
aggravate symptoms
of heart block.
● Monitor serum
electrolyte levels in
patients with renal
insufficiency because
they’re at risk for
magnesium toxicity.
● Be aware that
magnesium salts
aren’t intended for
long term use.
University of San Carlos
College of Nursing
Cebu City

   •Assess PR, urine

output, DTR, and
clonus every hour.
   •Observe for CNS
depression and
hypotonia in infant at
birth.
 University of San Carlos
College of Nursing
Cebu City

Methylergonovine Oxytocic A partial agonist or Contraindicated with CNS: Dizziness, ● Administer by IM

Maleate antagonist at alpha allergy to IM headache, tinnitus, injection or orally
(Methergine) receptors; as a methylergonovine, 0.2 mg after diaphoresis unless emergency
result, it increases hypertension, delivery of the requires IV use.
the strength, duration toxemia, lactation, placenta, after CV: Hypertension, Complications are
and frequency of pregnancy delivery of the palpitations, chest more frequent with IV
uterine contractions. anterior shoulder, pain, dyspnea use.
Use cautiously with or during
sepsis, obliterative puerperium. May GI: Nausea and ● Monitor postpartum
vascular disease, be repeated every vomiting women for blood
hepatic or renal 2-4 hours. pressure changes
impairment. and amount and
IV character of vaginal
Same dosage as bleeding.
IM, infuse slowly
over at least 60 ● Discontinue of
seconds. Monitor signs of toxicity
blood pressure occur.
very carefully as
severe ● Avoid prolonged
hypertensive use of the drug.
reaction can
occur.

ORAL
0.2 mg PO TID or
QID daily in the
puerperium for up
to 1 week.
University of San Carlos
College of Nursing
Cebu City