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Chapter 3-The Chemistry of Life: Organic Compounds: Multiple Choice

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Chapter 3—The Chemistry of Life: Organic Compounds

MULTIPLE CHOICE

1. Which of the following is not a property of carbon?


a. Carbon-to-carbon bonds are limited to single bonds.
b. Carbon has four valence electrons.
c. Carbon can form bonds to various other atoms.
d. Two carbon atoms can share three electron pairs with each other.
e. Carbon-to-carbon bonds are strong.
ANS: A PTS: 1 REF: p. 47 OBJ: Bloom's: Knowledge

2. The number of electron pairs shared between carbon 2 and 3 in the accompanying figure is:

a. one.
b. one and a half.
c. two.
d. three.
e. four
ANS: C PTS: 1 REF: p. 48 OBJ: Bloom's: Comprehension

3. The two molecules in the following figure represent:

a. ionized structures.
b. enantiomers.
c. secondary structures.
d. geometric isomers.
e. polymers.
ANS: D PTS: 1 REF: p. 48-49 OBJ: Bloom's: Comprehension

4. The highly polarized nature of compounds containing carboxyl groups can be attributed to the
presence of two:
a. highly electronegative carbon atoms.
b. highly electropositive carbon atoms.
c. highly electronegative oxygen atoms.
d. highly electropositive oxygen atoms.
e. highly electropositive nitrogen atoms.
ANS: C PTS: 1 REF: p. 49 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 31


5. This functional group is weakly basic because it can accept an H + ion:
a. hydroxyl
b. carbonyl
c. amino
d. phosphate
e. sulfhydryl
ANS: C PTS: 1 REF: p. 50 OBJ: Bloom's: Knowledge

6. Hydrocarbons are hydrophobic because:


a. the covalent bonds between hydrogen and carbon are nonpolar.
b. they contain oxygen atoms.
c. they exist as isomers.
d. the covalent bonds between carbon atoms are polar.
e. the hydrogen bonds between hydrogen and carbon are nonpolar.
ANS: A PTS: 1 REF: p. 48 OBJ: Bloom's: Comprehension

7. The chemical interactions of large organic molecules are largely determined by:
a. their solubility in water.
b. their functional groups.
c. their polar nature.
d. isomerization of these hydrocarbons into other forms.
e. the hydrogens bonded to the carbon atoms.
ANS: B PTS: 1 REF: p. 49 OBJ: Bloom's: Comprehension

8. Which of these terms is most inclusive?


a. monosaccharide
b. starch
c. polysaccharide
d. disaccharide
e. carbohydrate
ANS: E PTS: 1 REF: p. 51-52 OBJ: Bloom's: Comprehension

9. Carbohydrate molecules:
a. serve as structural components of human cell walls.
b. form the regulatory compounds known as enzymes.
c. are a source of energy.
d. help protect vital organs from damage.
e. contain the genetic information of a cell.
ANS: C PTS: 1 REF: p. 51 OBJ: Bloom's: Knowledge

10. A chemical reaction in which polymers are synthesized from their building blocks is called:
a. hydrolysis.
b. condensation.
c. oxidation.
d. reduction.
e. dissociation.
ANS: B PTS: 1 REF: p. 51 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 32


Figure 3-1
Use the figure below to answer the corresponding question(s).

11. The process illustrated in Figure 3-1 is called:


a. condensation.
b. protein synthesis.
c. hydrolysis.
d. dehydration synthesis.
e. denaturation.
ANS: C PTS: 1 REF: p. 51 OBJ: Bloom's: Application

12. The products of the process in Figure 3-1 are:


a. amino acids.
b. molecules of glycerol.
c. representative of a glycoside linkage.
d. enzymes.
e. monosaccharides.
ANS: E PTS: 1 REF: p. 51 OBJ: Bloom's: Application

13. In which of the following reactions must the equivalent of a water molecule be added in order to break
a bond?
a. fatty acids + glycerol  fat
b. glucose + fructose  sucrose
c. glycogen  glucose
d. alanine + glycine  dipeptide
e. glucose  cellulose
ANS: C PTS: 1 REF: p. 51 OBJ: Bloom's: Application

14. Which of the following illustrates hydrolysis?


a. the reaction of two monosaccharides to form a disaccharide
b. the reaction of two amino acids to form a dipeptide
c. the reaction of a hydrogen atom and a hydroxide ion to form water
d. the reaction of a fat to form glycerol and fatty acids
e. the formation of ATP from ADP and inorganic phosphate
ANS: D PTS: 1 REF: p. 51 | p. 57 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 33


15. Glucose dissolves in water because:
a. it ionizes.
b. it is a polysaccharide.
c. it has polar hydroxyl groups that interact with polar water molecules.
d. it has a very reactive primary structure.
e. it is hydrophobic.
ANS: C PTS: 1 REF: p. 52 OBJ: Bloom's: Application

16. The difference between a hexose and a pentose is that:


a. a hexose is saturated, and a pentose is undersaturated.
b. a hexose is hydrophilic, and a pentose is hydrophobic.
c. a hexose always has six hydroxyl groups, and a pentose always has five.
d. a hexose always has six carbons, but a pentose always has five carbons.
e. a hexose can be polymerized, but a pentose cannot.
ANS: D PTS: 1 REF: p. 52 OBJ: Bloom's: Comprehension

17. Monosaccharides are water soluble because:


a. they contain a large number of methyl groups.
b. they have a large number of polar hydroxyl groups.
c. they have at least one double bond between adjacent carbons.
d. they have large numbers of nonpolar carbons in their backbones.
e. they can form ring structures.
ANS: B PTS: 1 REF: p. 52 OBJ: Bloom's: Comprehension

18. Which pair is mismatched?


a. monsaccharidemaltose
b. disaccharidesucrose
c. polysaccharidecellulose
d. hexoseglucose
e. pentoseribose
ANS: A PTS: 1 REF: p. 53 OBJ: Bloom's: Comprehension

19. Which one of the following carbohydrates is the most structurally complex?
a. sucrose
b. fructose
c. cellulose
d. glucose
e. a disaccharide
ANS: C PTS: 1 REF: p. 54 OBJ: Bloom's: Comprehension

20. Amyloplasts are organelles that store:


a. fat.
b. starch.
c. protein.
d. lipids.
e. DNA.
ANS: B PTS: 1 REF: p. 54 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 34


21. A carbohydrate energy storage molecule found in animal liver and muscle cells is:
a. starch.
b. glycogen.
c. cellulose.
d. a fatty acid.
e. cholesterol.
ANS: B PTS: 1 REF: p. 54 OBJ: Bloom's: Comprehension

22. What macromolecule is composed entirely of beta-glucose units?


a. starch
b. chitin
c. glycogen
d. cellulose
e. protein
ANS: D PTS: 1 REF: p. 54 OBJ: Bloom's: Knowledge

23. Which of the following is NOT true of lipids?


a. They store energy.
b. They function as structural components of cellular membranes.
c. They function as hormones.
d. They are nonpolar.
e. They have many oxygen-containing functional groups.
ANS: E PTS: 1 REF: p. 56 OBJ: Bloom's: Knowledge

24. The hydrolysis of triacylglycerol will yield:


a. three fatty acids and one glycerol.
b. three glycerols and one fatty acid.
c. two fatty acids and three glycerols.
d. one fatty acid, one amino acid, and one glucose.
e. one fatty acid, one phosphate, and one glycerol.
ANS: A PTS: 1 REF: p. 57 OBJ: Bloom's: Comprehension

25. Which of the following molecules is not grouped with the lipids?
a. prostaglandins.
b. steroids.
c. cholesterol.
d. carotenoids.
e. glycoproteins
ANS: E PTS: 1 REF: p. 55 | p. 59 OBJ: Bloom's: Knowledge

26. A molecule of a saturated triacylglycerol contains:


a. the maximum number of double bonds between carbons in the fatty acid chains.
b. the maximum number of triple bonds between carbons in the fatty acid chains.
c. the maximum number of hydrogen atoms in the fatty acid chains.
d. fatty acid chains with both amino and carboxyl groups.
e. alternating single and double bonds between carbons in the fatty acid chains.
ANS: C PTS: 1 REF: p. 57 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 35


27. Which of the following statements concerning unsaturated fats is correct?
a. They are more common in animals.
b. They have no double bonds in the carbon chains of their fatty acids.
c. They are generally liquid at room temperature.
d. They contain more hydrogen than do saturated fats having the same number of carbon
atoms.
e. They have fewer fatty acids per fat molecule than do saturated fats.
ANS: C PTS: 1 REF: p. 57 OBJ: Bloom's: Knowledge

28. An amphipathic molecule has:


a. two polar ends.
b. two hydrophobic ends.
c. a hydrophobic and a hydrophilic portion.
d. only one hydrophobic end.
e. only one hydrophilic end.
ANS: C PTS: 1 REF: p. 58 OBJ: Bloom's: Knowledge

29. The major difference between a structural lipid, such as those in cell membranes, and a storage fat is
the fact that the structural lipid:
a. most commonly contains phosphate.
b. does not contain glycerol.
c. has four fatty acids attached to glucose.
d. is entirely hydrophobic.
e. is nonpolar.
ANS: A PTS: 1 REF: p. 56 | p. 59 OBJ: Bloom's: Comprehension

30. If you partially hydrogenate oleic acid, the resulting molecule most likely would:
a. decrease the risk of cardiovascular disease.
b. contain more double bonds.
c. lose a carbon atom.
d. lose a carboxyl group.
e. have a double bond changed from cis to trans.
ANS: E PTS: 1 REF: p. 58 OBJ: Bloom's: Application

31. You isolate a compound that is insoluble in water, has alternating single and double bonds, and has a
bright orange color. You correctly conclude that this compound is a:
a. protein.
b. nucleic acid.
c. polysaccharide.
d. steroid.
e. carotenoid.
ANS: E PTS: 1 REF: p. 59 OBJ: Bloom's: Analysis

32. Which of the following statements concerning steroids is FALSE?


a. They can function as hormones.
b. They are exemplified by cholesterol.
c. They consist of four attached carbon rings.
d. They are synthesized from isoprene units.
e. They contain phosphodiester linkages.
ANS: E PTS: 1 REF: p. 59 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 36


33. The most abundant molecules in this structure are:

a. structural proteins.
b. polysaccharides.
c. triacylglycerols.
d. phospholipids.
e. polypeptides.
ANS: D PTS: 1 REF: p. 58 OBJ: Bloom's: Knowledge

34. The primary difference between the amino acids commonly found in proteins is in their:
a. R or variable groups.
b. number of potassium groups.
c. number of phosphate groups.
d. number of carbonyl groups.
e. number of asymmetric carbons.
ANS: A PTS: 1 REF: p. 61 OBJ: Bloom's: Knowledge

35. Some proteins are important biological buffers because:


a. they react with water to produce carbon dioxide, which neutralizes acids.
b. they contain acidic as well as basic groups.
c. they are able to absorb great amounts of carbon dioxide during condensation reactions.
d. they produce carbonic acid upon hydrolysis.
e. they contain nonpolar groups that exclude water molecules.
ANS: B PTS: 1 REF: p. 61 OBJ: Bloom's: Comprehension

36. Regulatory proteins:


a. defend against foreign invaders.
b. store nutrients.
c. catalyze a specific chemical reaction.
d. control the expression of specific genes.
e. strengthen and protect cells and tissues.
ANS: D PTS: 1 REF: p. 60 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 37


37. The following amino acid would be characterized as __________ based on the chemical properties of
its side chain.

a. nonpolar
b. acidic
c. basic
d. hydrophilic
e. electrically charged
ANS: A PTS: 1 REF: p. 63 OBJ: Bloom's: Application

38. At which level of protein structure are peptide bonds most important?
a. primary
b. secondary
c. tertiary
d. quaternary
e. globular
ANS: A PTS: 1 REF: p. 61 OBJ: Bloom's: Knowledge

39. Which of the following is responsible for the alpha-helical structure of proteins?
a. hydrophobic interactions
b. nonpolar covalent bonds
c. ionic interactions
d. hydrogen bonds
e. polar covalent bonds
ANS: D PTS: 1 REF: p. 64 OBJ: Bloom's: Knowledge

40. Proteins with alpha-helical forms exhibit this property:


a. strength.
b. elasticity.
c. heat stability.
d. rigidity.
e. hydrophobicity.
ANS: B PTS: 1 REF: p. 64 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 38


41. If tyrosine and isoleucine undergo condensation, the new bond that is formed is between the:
a. oxygen of the R group and the hydrogen of the amino group.
b. carbon of the R group and the nitrogen of the amino group.
c. carbon of the carboxyl group and the hydrogen of the R group.
d. carbon of the carboxyl group and the hydrogen of the amino group.
e. carbon of the carboxyl group and the nitrogen of the amino group.
ANS: E PTS: 1 REF: p. 61 | p. 64 OBJ: Bloom's: Application

Figure 3-2
Use the figure below to answer the corresponding question(s).

42. In Figure 3-2, ionic bonds would form between the R groups of which amino acids?
a. 1 and 3
b. 2 and 4
c. 3 and 5
d. 4 and 6
e. 3 and 6
ANS: B PTS: 1 REF: p. 65 OBJ: Bloom's: Application

43. Hydrophobic interactions would occur between the R groups of which two amino acids in Figure 3-2?
a. 1 and 4
b. 2 and 5
c. 3 and 6
d. 2 and 4
e. 3 and 5
ANS: C PTS: 1 REF: p. 65 OBJ: Bloom's: Application

44. The tertiary structure of proteins is typified by the:


a. association of several polypeptide chains by weak bonds.
b. order in which amino acids are joined in a peptide chain.
c. bonding of two amino acids to form a dipeptide.
d. folding of a peptide chain to form an alpha helix.
e. three-dimensional shape of an individual polypeptide chain.
ANS: E PTS: 1 REF: p. 64-65 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 39


45. All of the following types of chemical bonds are responsible for maintaining the tertiary structure of
this polypeptide except:

a. ionic bonds.
b. hydrogen bonds.
c. hydrophobic interactions.
d. disulfide bonds.
e. peptide bonds.
ANS: E PTS: 1 REF: p. 65 OBJ: Bloom's: Knowledge

46. This functional group forms bridges that help stabilize protein quaternary structure:
a. hydroxyl
b. carbonyl
c. amino
d. phosphate
e. sulfhydryl
ANS: E PTS: 1 REF: p. 66 OBJ: Bloom's: Knowledge

47. Molecular chaperones are proteins that mediate the folding process of:
a. other proteins.
b. amino acids.
c. lipids.
d. DNA.
e. sugars.
ANS: A PTS: 1 REF: p. 66 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 40


48. If the differently shaded portions of this molecule represent different polypeptide chains, then this
figure is representative of:

a. an amino acid.
b. the quaternary structure of a protein.
c. a steroid hormone.
d. cellulose.
e. a carotenoid.
ANS: B PTS: 1 REF: p. 65 | p. 67 OBJ: Bloom's: Comprehension

49. Which of the following statements is true of proteins?


a. Proteins lose some or all of their normal activity if their three-dimensional structure is
disrupted.
b. Proteins are composed of ribose, phosphate, and a nitrogen-containing base.
c. The activity of proteins is independent of temperature and pH.
d. Denaturation is usually reversible.
e. All proteins are enzymes.
ANS: A PTS: 1 REF: p. 67 OBJ: Bloom's: Knowledge

50. This molecule transmits heredity information:


a. cholesterol.
b. adenosine triphosphate.
c. nucleic acid.
d. fatty acid.
e. polysaccharide.
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Knowledge

51. Which of the following statements is false?


a. DNA is usually composed of two nucleotide strands.
b. DNA contains deoxyribose.
c. DNA does not normally contain uracil.
d. The nucleotides of DNA are linked by phosphodiester linkages.
e. DNA does not normally contain a phosphate group.
ANS: E PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

52. DNA most directly determines which __________ are made by a cell.
a. polysaccharides
b. polypeptides
c. nucleotides
d. triglycerides
e. fatty acids
ANS: B PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 41


53. Which of the following statements best summarizes the differences between RNA and DNA?
a. RNA is a protein and DNA is a nucleic acid.
b. DNA is a polymer and RNA is a monomer.
c. DNA comprises the genes, while RNA is a direct participant in the process of protein
synthesis.
d. RNA is a single-stranded form of DNA.
e. DNA is the primary energy currency of all cells.
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

Figure 3-3
Use the figure to answer the corresponding question(s).

54. The molecular fragment represented in Figure 3-3 is:


a. ATP.
b. RNA.
c. a protein.
d. a nucleotide.
e. a polysaccharide.
ANS: B PTS: 1 REF: p. 68-69 OBJ: Bloom's: Application

55. The type of connection between the atoms at the point labeled 1 in Figure 3-3 is:
a. a peptide bond.
b. a glycoside linkage.
c. a disulfide bond.
d. a phosphodiester linkage.
e. a hydrogen bond.
ANS: D PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 42


56. Analysis of a certain polymer shows that it contains phosphate groups, ribose groups, and pyrimidines.
Based on this information, which of the following is the best description of this compound?
a. It is most likely ribonucleic acid.
b. It is DNA.
c. It is an inorganic compound.
d. It contains thymine.
e. It is a polypeptide.
ANS: A PTS: 1 REF: p. 68 OBJ: Bloom's: Application

57. Which pair matches the correct macromolecule with the bond that joins its subunits?
a. polysaccharidepeptide bond
b. triacylglycerolglycosidic linkage
c. nucleic acidphosphodiester linkage
d. proteinester linkage
e. steroidpeptide bond
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

58. When a nucleic acid undergoes hydrolysis, the resulting subunits are:
a. amino acids.
b. monosaccharides.
c. nucleotides.
d. fatty acids.
e. carotenoids.
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

59. ATP is important in living organisms because:


a. like all other nucleic acids, it stores hereditary information.
b. like RNA, it acts as a source code for the formation of proteins.
c. it can transfer some of its energy to other chemicals.
d. it is an important structural component of cell membranes.
e. it is easily converted to starch for long-term storage.
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 43


60. Which portion of the following molecule is most directly involved in transferring energy?

a. 1
b. 2
c. 3
d. 1 and 2
e. 2 and 3
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension

SHORT ANSWER

1. What does the term "functional group" mean in reference to the structure of organic molecules?
Identify two types of functional groups and describe their chemical properties.

ANS:
A functional group is a group of atoms that is attached to the carbon skeleton and determines the types
of chemical reactions and other associations in which the resulting organic molecule participates.
Table3-1 on page 50 shows the main functional groups and their properties.

PTS: 1 REF: p. 49-50 OBJ: Bloom's: Comprehension

2. Compare and contrast the structure, physical characteristics, and biological functions of two of the
following: fats, steroids, and phospholipids.

ANS:
In general, all three molecules consist of a carbon skeleton. Fats and steroids are nonpolar whereas
phospholipids are amphipathic. Fats generally function as storage forms of energy and consist of three
fatty acids attached to glycerol. Steroids consist of four attached rings and have many functions,
including hormones and components of membranes. Phospholipids consist of two fatty acids and one
phosphate group attached to glycerol; they are the principal components of membranes.

PTS: 1 REF: p. 56-59 OBJ: Bloom's: Analysis

3. Identify three functions of proteins other than enzymes and briefly discuss or describe each.

ANS:
Table 3-2 on page 60 lists the main classes, functions, and examples of proteins.

PTS: 1 REF: p. 60 OBJ: Bloom's: Comprehension

Chapter 3—The Chemistry of Life: Organic Compounds 44


4. Identify the levels of organization for protein molecules, and list the type(s) of bond(s) involved in
establishing each structural level.

ANS:
Primary structure: peptide bonds
Secondary structure: hydrogen bonds between parts of the backbone
Tertiary structure: the following bonds between R groups in the same polypeptide: hydrogen bonds,
ionic bonds, hydrophobic interactions, and covalent disulfide bridges
Quaternary structure: the same types of bonds as for the tertiary structure except that these bonds
occur between different polypeptide chains

PTS: 1 REF: p. 61-65 OBJ: Bloom's: Comprehension

MODIFIED TRUE/FALSE

1. By definition, geometric isomers are mirror images of each other.


__________________

ANS: F, enantiomers

PTS: 1 REF: p. 48 OBJ: Bloom's: Knowledge

2. The carboxyl group can exist in an ionized form and also in a nonionized form.
__________________

ANS: T PTS: 1 REF: p. 49


OBJ: Bloom's: Knowledge

3. The phosphate group is a nonpolar group.


__________________

ANS: F, polar

PTS: 1 REF: p. 50 OBJ: Bloom's: Comprehension

4. Water is always released as a product in hydrolysis reactions.


__________________

ANS: F, condensation

PTS: 1 REF: p. 51 OBJ: Bloom's: Comprehension

5. When glucose and fructose undergo condensation, maltose is produced as a product.


__________________

ANS: F, sucrose

PTS: 1 REF: p. 53 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 45


6. A disaccharide is composed of two monosaccharides joined by a glycosidic linkage.
__________________

ANS: T PTS: 1 REF: p. 53


OBJ: Bloom's: Knowledge

7. Glycogen consists of beta-glucose monomers.


__________________

ANS: F, alpha

PTS: 1 REF: p. 54 OBJ: Bloom's: Knowledge

8. Chitin is a polymer composed of N-acetyl glucosamine monomers.


__________________

ANS: T PTS: 1 REF: p. 55


OBJ: Bloom's: Knowledge

9. Fats high in unsaturated fatty acids tend to be solid at room temperature.


__________________

ANS: F, liquid

PTS: 1 REF: p. 57 OBJ: Bloom's: Knowledge

10. Carotenoids are composed of isoprene subunits.


__________________

ANS: T PTS: 1 REF: p. 59


OBJ: Bloom's: Knowledge

11. An essential amino acid is one that the body cannot synthesize in sufficient amounts.
__________________

ANS: T PTS: 1 REF: p. 61


OBJ: Bloom's: Knowledge

12. A beta-pleated sheet is an example of a protein’s tertiary structure.


__________________

ANS: F, secondary

PTS: 1 REF: p. 64 OBJ: Bloom's: Knowledge

13. Molecular chaperones mediate the folding of other protein molecules.


__________________

ANS: T PTS: 1 REF: p. 66


OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 46


14. A single protein may have several domains.
__________________

ANS: T PTS: 1 REF: p. 67


OBJ: Bloom's: Knowledge

15. A pyrimidine is double-ring molecule.


__________________

ANS: F, single

PTS: 1 REF: p. 68 OBJ: Bloom's: Knowledge

16. Cyclic AMP is a type of nucleotide.


__________________

ANS: T PTS: 1 REF: p. 68


OBJ: Bloom's: Knowledge

MATCHING

Match the molecule with the appropriate word or phrase.


a. carbohydrate c. nucleic acid
b. lipid d. protein
1. most are nonpolar
2. starch
3. consist of monomers having 20 different types
4. a beta-pleated sheet is one typical structure
5. monomers are joined by a glycosidic linkage
6. contains purines and pyrimidines
7. cellulose
8. cholesterol
9. may contain thymine
10. monomers are joined by phosphodiester linkages
11. can be denatured by temperature and/or pH
12. some are composed of fatty acids joined to glycerol

1. ANS: B PTS: 1 REF: p. 56 OBJ: Bloom's: Comprehension


2. ANS: A PTS: 1 REF: p. 51 OBJ: Bloom's: Knowledge
3. ANS: D PTS: 1 REF: p. 61 OBJ: Bloom's: Knowledge
4. ANS: D PTS: 1 REF: p. 64 OBJ: Bloom's: Knowledge
5. ANS: A PTS: 1 REF: p. 53 OBJ: Bloom's: Knowledge
6. ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Knowledge
7. ANS: A PTS: 1 REF: p. 54 OBJ: Bloom's: Knowledge
8. ANS: B PTS: 1 REF: p. 59 OBJ: Bloom's: Knowledge
9. ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Knowledge
10. ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Knowledge
11. ANS: D PTS: 1 REF: p. 67 OBJ: Bloom's: Knowledge
12. ANS: B PTS: 1 REF: p. 57 OBJ: Bloom's: Knowledge

Chapter 3—The Chemistry of Life: Organic Compounds 47


ESSAY

1. Methane, which is composed of carbon and hydrogen, lacks functional groups and is a gas at room
temperature. Upon replacing one of the hydrogen atoms with a hydroxyl group, methane is converted
to methanol, which is a liquid at room temperature. Explain the reason behind this difference in
physical properties.

ANS:
Concepts to Consider: Polar nature of methanol compared to methane is due to polar hydroxyl group;
polarity of methanol allows formation of hydrogen bonds and increases cohesiveness of this chemical.

PTS: 1 REF: p. 49 OBJ: Bloom's: Analysis


TOP: Discussion or Thought Questions

2. Why is carbon ideally suited to be the "backbone" in molecules produced by living organisms?

ANS:
Concepts to Consider: Ability of carbon to bond with four other atoms; the nature of the strong
covalent bond linking adjacent carbon atoms; the ability of carbon to form linear, branched, and ring
structures; the insolubility of hydrocarbons in water.

PTS: 1 REF: p. 47-48 OBJ: Bloom's: Comprehension


TOP: Discussion or Thought Questions

3. Sickle cell anemia is a genetic disease caused by the replacement of one amino acid in the hemoglobin
molecule. This replacement changes the shape and function of the hemoglobin protein in dramatic
ways, which can sometimes be lethal. How can the substitution of one amino acid lead to such drastic
results?

ANS:
Concepts to Consider: Amino acid sequence determines primary structure; primary structure affects
the shape of proteins; the shape of proteins determines their function.

PTS: 1 REF: p. 61-68 OBJ: Bloom's: Synthesis


TOP: Discussion or Thought Questions

Chapter 3—The Chemistry of Life: Organic Compounds 48

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