Chapter 3-The Chemistry of Life: Organic Compounds: Multiple Choice
Chapter 3-The Chemistry of Life: Organic Compounds: Multiple Choice
Chapter 3-The Chemistry of Life: Organic Compounds: Multiple Choice
MULTIPLE CHOICE
2. The number of electron pairs shared between carbon 2 and 3 in the accompanying figure is:
a. one.
b. one and a half.
c. two.
d. three.
e. four
ANS: C PTS: 1 REF: p. 48 OBJ: Bloom's: Comprehension
a. ionized structures.
b. enantiomers.
c. secondary structures.
d. geometric isomers.
e. polymers.
ANS: D PTS: 1 REF: p. 48-49 OBJ: Bloom's: Comprehension
4. The highly polarized nature of compounds containing carboxyl groups can be attributed to the
presence of two:
a. highly electronegative carbon atoms.
b. highly electropositive carbon atoms.
c. highly electronegative oxygen atoms.
d. highly electropositive oxygen atoms.
e. highly electropositive nitrogen atoms.
ANS: C PTS: 1 REF: p. 49 OBJ: Bloom's: Knowledge
7. The chemical interactions of large organic molecules are largely determined by:
a. their solubility in water.
b. their functional groups.
c. their polar nature.
d. isomerization of these hydrocarbons into other forms.
e. the hydrogens bonded to the carbon atoms.
ANS: B PTS: 1 REF: p. 49 OBJ: Bloom's: Comprehension
9. Carbohydrate molecules:
a. serve as structural components of human cell walls.
b. form the regulatory compounds known as enzymes.
c. are a source of energy.
d. help protect vital organs from damage.
e. contain the genetic information of a cell.
ANS: C PTS: 1 REF: p. 51 OBJ: Bloom's: Knowledge
10. A chemical reaction in which polymers are synthesized from their building blocks is called:
a. hydrolysis.
b. condensation.
c. oxidation.
d. reduction.
e. dissociation.
ANS: B PTS: 1 REF: p. 51 OBJ: Bloom's: Knowledge
13. In which of the following reactions must the equivalent of a water molecule be added in order to break
a bond?
a. fatty acids + glycerol fat
b. glucose + fructose sucrose
c. glycogen glucose
d. alanine + glycine dipeptide
e. glucose cellulose
ANS: C PTS: 1 REF: p. 51 OBJ: Bloom's: Application
19. Which one of the following carbohydrates is the most structurally complex?
a. sucrose
b. fructose
c. cellulose
d. glucose
e. a disaccharide
ANS: C PTS: 1 REF: p. 54 OBJ: Bloom's: Comprehension
25. Which of the following molecules is not grouped with the lipids?
a. prostaglandins.
b. steroids.
c. cholesterol.
d. carotenoids.
e. glycoproteins
ANS: E PTS: 1 REF: p. 55 | p. 59 OBJ: Bloom's: Knowledge
29. The major difference between a structural lipid, such as those in cell membranes, and a storage fat is
the fact that the structural lipid:
a. most commonly contains phosphate.
b. does not contain glycerol.
c. has four fatty acids attached to glucose.
d. is entirely hydrophobic.
e. is nonpolar.
ANS: A PTS: 1 REF: p. 56 | p. 59 OBJ: Bloom's: Comprehension
30. If you partially hydrogenate oleic acid, the resulting molecule most likely would:
a. decrease the risk of cardiovascular disease.
b. contain more double bonds.
c. lose a carbon atom.
d. lose a carboxyl group.
e. have a double bond changed from cis to trans.
ANS: E PTS: 1 REF: p. 58 OBJ: Bloom's: Application
31. You isolate a compound that is insoluble in water, has alternating single and double bonds, and has a
bright orange color. You correctly conclude that this compound is a:
a. protein.
b. nucleic acid.
c. polysaccharide.
d. steroid.
e. carotenoid.
ANS: E PTS: 1 REF: p. 59 OBJ: Bloom's: Analysis
a. structural proteins.
b. polysaccharides.
c. triacylglycerols.
d. phospholipids.
e. polypeptides.
ANS: D PTS: 1 REF: p. 58 OBJ: Bloom's: Knowledge
34. The primary difference between the amino acids commonly found in proteins is in their:
a. R or variable groups.
b. number of potassium groups.
c. number of phosphate groups.
d. number of carbonyl groups.
e. number of asymmetric carbons.
ANS: A PTS: 1 REF: p. 61 OBJ: Bloom's: Knowledge
a. nonpolar
b. acidic
c. basic
d. hydrophilic
e. electrically charged
ANS: A PTS: 1 REF: p. 63 OBJ: Bloom's: Application
38. At which level of protein structure are peptide bonds most important?
a. primary
b. secondary
c. tertiary
d. quaternary
e. globular
ANS: A PTS: 1 REF: p. 61 OBJ: Bloom's: Knowledge
39. Which of the following is responsible for the alpha-helical structure of proteins?
a. hydrophobic interactions
b. nonpolar covalent bonds
c. ionic interactions
d. hydrogen bonds
e. polar covalent bonds
ANS: D PTS: 1 REF: p. 64 OBJ: Bloom's: Knowledge
Figure 3-2
Use the figure below to answer the corresponding question(s).
42. In Figure 3-2, ionic bonds would form between the R groups of which amino acids?
a. 1 and 3
b. 2 and 4
c. 3 and 5
d. 4 and 6
e. 3 and 6
ANS: B PTS: 1 REF: p. 65 OBJ: Bloom's: Application
43. Hydrophobic interactions would occur between the R groups of which two amino acids in Figure 3-2?
a. 1 and 4
b. 2 and 5
c. 3 and 6
d. 2 and 4
e. 3 and 5
ANS: C PTS: 1 REF: p. 65 OBJ: Bloom's: Application
a. ionic bonds.
b. hydrogen bonds.
c. hydrophobic interactions.
d. disulfide bonds.
e. peptide bonds.
ANS: E PTS: 1 REF: p. 65 OBJ: Bloom's: Knowledge
46. This functional group forms bridges that help stabilize protein quaternary structure:
a. hydroxyl
b. carbonyl
c. amino
d. phosphate
e. sulfhydryl
ANS: E PTS: 1 REF: p. 66 OBJ: Bloom's: Knowledge
47. Molecular chaperones are proteins that mediate the folding process of:
a. other proteins.
b. amino acids.
c. lipids.
d. DNA.
e. sugars.
ANS: A PTS: 1 REF: p. 66 OBJ: Bloom's: Knowledge
a. an amino acid.
b. the quaternary structure of a protein.
c. a steroid hormone.
d. cellulose.
e. a carotenoid.
ANS: B PTS: 1 REF: p. 65 | p. 67 OBJ: Bloom's: Comprehension
52. DNA most directly determines which __________ are made by a cell.
a. polysaccharides
b. polypeptides
c. nucleotides
d. triglycerides
e. fatty acids
ANS: B PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension
Figure 3-3
Use the figure to answer the corresponding question(s).
55. The type of connection between the atoms at the point labeled 1 in Figure 3-3 is:
a. a peptide bond.
b. a glycoside linkage.
c. a disulfide bond.
d. a phosphodiester linkage.
e. a hydrogen bond.
ANS: D PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension
57. Which pair matches the correct macromolecule with the bond that joins its subunits?
a. polysaccharidepeptide bond
b. triacylglycerolglycosidic linkage
c. nucleic acidphosphodiester linkage
d. proteinester linkage
e. steroidpeptide bond
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension
58. When a nucleic acid undergoes hydrolysis, the resulting subunits are:
a. amino acids.
b. monosaccharides.
c. nucleotides.
d. fatty acids.
e. carotenoids.
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension
a. 1
b. 2
c. 3
d. 1 and 2
e. 2 and 3
ANS: C PTS: 1 REF: p. 68 OBJ: Bloom's: Comprehension
SHORT ANSWER
1. What does the term "functional group" mean in reference to the structure of organic molecules?
Identify two types of functional groups and describe their chemical properties.
ANS:
A functional group is a group of atoms that is attached to the carbon skeleton and determines the types
of chemical reactions and other associations in which the resulting organic molecule participates.
Table3-1 on page 50 shows the main functional groups and their properties.
2. Compare and contrast the structure, physical characteristics, and biological functions of two of the
following: fats, steroids, and phospholipids.
ANS:
In general, all three molecules consist of a carbon skeleton. Fats and steroids are nonpolar whereas
phospholipids are amphipathic. Fats generally function as storage forms of energy and consist of three
fatty acids attached to glycerol. Steroids consist of four attached rings and have many functions,
including hormones and components of membranes. Phospholipids consist of two fatty acids and one
phosphate group attached to glycerol; they are the principal components of membranes.
3. Identify three functions of proteins other than enzymes and briefly discuss or describe each.
ANS:
Table 3-2 on page 60 lists the main classes, functions, and examples of proteins.
ANS:
Primary structure: peptide bonds
Secondary structure: hydrogen bonds between parts of the backbone
Tertiary structure: the following bonds between R groups in the same polypeptide: hydrogen bonds,
ionic bonds, hydrophobic interactions, and covalent disulfide bridges
Quaternary structure: the same types of bonds as for the tertiary structure except that these bonds
occur between different polypeptide chains
MODIFIED TRUE/FALSE
ANS: F, enantiomers
2. The carboxyl group can exist in an ionized form and also in a nonionized form.
__________________
ANS: F, polar
ANS: F, condensation
ANS: F, sucrose
ANS: F, alpha
ANS: F, liquid
11. An essential amino acid is one that the body cannot synthesize in sufficient amounts.
__________________
ANS: F, secondary
ANS: F, single
MATCHING
1. Methane, which is composed of carbon and hydrogen, lacks functional groups and is a gas at room
temperature. Upon replacing one of the hydrogen atoms with a hydroxyl group, methane is converted
to methanol, which is a liquid at room temperature. Explain the reason behind this difference in
physical properties.
ANS:
Concepts to Consider: Polar nature of methanol compared to methane is due to polar hydroxyl group;
polarity of methanol allows formation of hydrogen bonds and increases cohesiveness of this chemical.
2. Why is carbon ideally suited to be the "backbone" in molecules produced by living organisms?
ANS:
Concepts to Consider: Ability of carbon to bond with four other atoms; the nature of the strong
covalent bond linking adjacent carbon atoms; the ability of carbon to form linear, branched, and ring
structures; the insolubility of hydrocarbons in water.
3. Sickle cell anemia is a genetic disease caused by the replacement of one amino acid in the hemoglobin
molecule. This replacement changes the shape and function of the hemoglobin protein in dramatic
ways, which can sometimes be lethal. How can the substitution of one amino acid lead to such drastic
results?
ANS:
Concepts to Consider: Amino acid sequence determines primary structure; primary structure affects
the shape of proteins; the shape of proteins determines their function.