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Drug Mechanism of Action Indication Contraindication Adverse Effect Nursing Responsibility Generic Name

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Drug Mechanism of Action Indication Contraindication Adverse Effect Nursing Responsibility

Generic Name: Ranitidine is a specific, It is to treat ulcers of  History of acute •headache - Check/ask client if he/she has
Ranitidine rapidly acting histamine the stomach and porphyria •constipation allergies.
H2-antagonist. It inhibits intestines and prevent  Hypersensitivity •diarrhea
basal and stimulated them from coming back to ranitidine or •nausea and - Check the label and dosage
secretion of gastric acid, after they have healed. components of vomiting prior to administration.
reducing both the volume, This medication is also the formulation •dizziness Interventions:
and the acid and pepsin used to treat certain •hair loss
content of the secretion. stomach and throat •Inflammation of •Injection may be given as a
(esophagus) problems liver slow.
(such as erosive •Changes in brain •Be alert for early signs of
esophagitis, function hepatotoxicity
Drug Classification: gastroesophageal reflux •Abnormal heart •Potential toxicity results from
Histamine H2 disease-GERD, Zollinger- rate decreased clearance
Antagonists Ellison syndrome). (elimination) and therefore
prolonged action; greatest in the
Dosage: older adult patients or those
50mg IV q8 x 3 doses with hepatic or renal
dysfunction.
Route:
IV injection Teaching points:
•May experience constipation or
diarrhea, nausea and vomiting,
enlargement of breasts,
impotence or decreased libido,
and headache.

•Report sore throat, fever


unusual bruising or bleeding,
tarry stool, confusion,
hallucinations, dizziness, severe
headache and muscle or joint
pain.
Drug Mechanism of Action Indication Contraindication Adverse Effect Nursing Responsibility
Generic Name: Omeprazole is a proton To treat certain • Hypersensitivity to >Dizziness -Nurse should use a double-
Omeprazole pump inhibitor. It inhibits stomach omeprazole, other >Rash ended transfer needle and
the parietal cell H+ / K+ and esophagus proton pump inhibitors. >Headache attach to the injection
Brand Name: ATP pump, the final step problems • Concomitant use with >Nausea membrane of the infusion
Losec, Prilosec of acid production. In (such as acid reflux, products containing >Vomiting bag. Connect the other
turn, omeprazole ulcers). It relieves rilpivirine. >Constipation needle-end from the vial with
suppresses gastric basal symptoms such as >Upper respiratory freeze-dried omeprazole.
and stimulated acid heartburn, difficulty Cautions: tract Make sure all omeprazole is
secretion. On the other swallowing, and May increase risk >infection dissolved.
hand, it reduces acid persistent cough. of fractures, >Back pain
secretion gastrointestinal infections. >Abdominal pain - Advise patient to avoid
in the stomach by binding infections. alcohol and foods that may
irreversibly to the enzyme cause an increase in GI
Drug class: H+,K+- ATPase. It inhibits irritation.
proton-pump the final pathway
inhibitors involved in acid secretion - Instruct client to take 30-60
and effectively inhibits minutes prior to eating. And if
Dosage: the capsule it should be swallowed
40mg IV active proton pumps. whole.

Route: - Nurse should advise the


Intravenous infusion client to promptly report any
and PO sign of adverse reactions.

- Nurse should instruct client


to report pain at the IV site.

- Nurse should advise client to


report immediately when GI
discomfort, nausea, diarrhea
occurs.

- Nurse should evaluate for


therapeutic response (relief of
GI symptoms).

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