DOC

Disease Drug
Travelers’ diarrhea Bismuth Subsalicylate (BSS) + Ciprofloxacin 500 mg BID, 3 dys
Listeriosis  Ampicillin
Clostridium difficile infection  Metronidazole
CAP  Amoxicillin / Clavulanic acid
Trichomoniasis  Metronidazole
Urinary Tract Infections (UTI)  Ciprofloxacin / Nitrofurantoin / Trimethoprim /
Sulfamethoxazole
ER cardiac arrhythmia  Lidocaine
Hepatic encephalopathy  Lactulose (Absorbs ammonia)
Constipation (Osmotic laxative)  Lactulose
Cardiogenic & septic shock  Dopamine (B1 action)
Trichomoniasis  Metronidazole
Stenotrophomonas maltophilia  Sulfonamides
(nosocomial infections, hospital
acquired)
Pneumocystis Pneumonia (PCP):  Pentamidine “by inhalation to prevent PCP, by injection to
treat PCP”
P. Carinii  Cotrimoxazole
Meningitis  Penicillins
 Cephalosporins
 Vancomycin
 If Viral: Acyclovir I.V
Meningococcal encephalitis  Penicillins
Gonorrhea  Ceftriaxone (125 mg, I.M, single dose)
 Cefixime (400 mg, oral, single dose)
 Ciprofloxacin (500 mg, Oral, Single dose)
Nosocomial infections  Cephalosporins 3rd G.
Otitis Externa (Swimmer’s ear)  Gentamycin ear drops
Otitis media  Amoxicillin + Clavulanic acid
Sinusitis  Amoxicillin
Pharyngitis  Penicillin G
UTI  Sulfamethoxazole + Trimethoprim
Food intoxication  Ciprofloxacin + Metronidazole + lot of fluids
Colitis associated with AB  Vancomycin
Paget Disease  Pamidronate
Acute Agitation in seniors  Quetiapine
Trigeminal neuralgia  Carbamazepine, Gabapentin
Postherpetic Neuralgia  Pregabalin
“Nerve pain by VZV”
Chronic Inflammatory Disease  Olsalazine, Mesalamine (with so sulfa)
 Sulfasalazine (has sulfa)
Raynaud’s disease  CCB “Non-dihydropyridine” (Verapamil, Diltiazem)
Brain
Anxiety disorders  Clomipramine (TCA) / BDZ
Panic disorders  Paroxetine – Sertaline - Venlafaxine
PTSD  Paroxetine
General Anxiety disorder (GAD)  Buspirone, Venlafaxine, Paroxetine
Obsessive Compulsive disorder  Fluoxetine, Paroxetine
(OCD)
Acute agitation in adults  Quetiapine
Absence Seizures  Ethosuximide
ADHD  Clonidine
Status Epilepticus  Diazepam / Lorazepam IM
Mal Epileptic seizures  Diazepam / Lorazepam
Sleep Disorders  Non-BDZ Zolpidem, Zaleplon
Major depression  Bupropion
Delirium  Haloperidol
Resistant psychosis  Clozapine
Drug induced parkinsonism  Anticholinergics “Benzatropine, Trihexyphenidyl”
Lewy body dementia  Rivastigmine
Anxiety disorders  Clomipramine (TCA)
Resistant Schizophrenia  Clozapine
Alzheimer’s disease  Donepezil (Ach E I)
Bipolar disorder & manic  Lithium “Li”
Parkinsonism  L-DOPA
OTC for Dermatological Conditions
Head lice  Permethrin 1% OTC
Acne  Benzoyl peroxide (gel) / Tretinoin / Topical AB: Erythromycin
Scabies  Permethrin 5% (all over the body, Not < 2yrs)
Atopic dermatitis  Topical Cortisol 5%
Diaper rash  Uncomplicated: Zn Oxide, Petroleum jelly
 Complicated: Nystatin, Clotrimazole
Sexually Transmitted Diseases  Metronidazole
“Trichomoniasis,
Except Gonorrhea
Gonorrhea  Ceftriaxone IV (3rd G. Cephalosporins)
Nosocomial Infections
Anthrax  Ciprofloxacin / Doxycycline
Pseudomonal infections  Ciprofloxacin
  Mezlocillin, Carbenicillin, Ticarcillin
Cystitis (most common UTI)  Cotrimoxazole, CS
Typhoid fever  Ciprofloxacin
GIT bleeding  PPI
Aspirin induced asthma  Montelukast & Zafirlukast
Children with viral infection  Acetaminophen

CVS
Uncomplicated hypertension >65  Thiazides
>65  βB
HtN + ClCr  Loop diuretics
HtN + CHF  CCB “Non-dihydropyridine” (Verapamil, Diltiazem)
CAD  ACEI / ARBs
HtN + Diabetes  ACEI
Stable Angina  βB
Prinzmetal Angina  Felodipine
Hypertensive Crisis  Na Nitroprusside IV

Ascites & Hirsutism  Spironolactone
Nephrogenic Diabetes Insipidus  Amiloride
Morning Sickness  Rx: Diclectin “Cobalamin + Doxylamine”.
 OTC: Dimenhydrinate
 Herbal ginger root
Intestinal worm  OTC: Pyrantal Pamoate (C.I: in pregnancy)
 Piperazine adipate (used in pregnancy)
 Rx: Mebendazole
Migraine  Sumatriptan / Ergot alkaloids (for ttt)
 Methysergide maleate
H-pylori  Triple therapy “clarithromycin + omeprazole + amoxicillin”
Irritable Bowel Disease  5-ASA
Bulimia Nervosa  Fluoxetine “SSRI” / Venlafaxine
Anorexia Nervosa  Domperidone / Metoclopramide
Urinary incontinence in adults  Oxybutynin
Osteoarthritis  Non-Rx: Acetaminophen
COPD  Ipratropium Bromide
Smoking Cession  Bupropion / Varenicline
Multiple Sclerosis  Baclofen & Dantrolene
BPH  Finasteride – Dutasteride
Nocturnal Enuresis  Imipramine / Desmopressin
Rheumatoid Arthritis  Methotrexate / Leflunomide
Pregnancy:
 N & V: Diclectin (Pyridoxine + Doxylamine) / Dimenhydrinate (OTC) / Ginger
 HtN: Methyl dopa
 Safe AB: Cephalexin / Amoxicillin / Ampicillin / Erythromycin
C.I: Amantadine / Nalidixic acid / TC / sulfa
 Diabetes: Insulin aspart.
 Depression: Fluoxetine (Prozac).
 Epilepsy: Carbamazepine.
 Hyperthyroidism: PTU (not cross placenta).
 UTI: Cephalosporins “Cephalexin” & Nitrofurantoin
 Acne: Erythromycin
 Constipation: Psyllium / Stool softener
 Ulcerative Colitis: 5-ASA / Sulfasalazine
 Diarrhea: Loperamide

Nausea & Vomiting

 Pregnancy: Diclectin (Pyridoxine + Doxylamine) / Dimenhydrinate (OTC) / Ginger
 Post chemotherapy: Metoclopramide (D Rs Atg), Prochlorperazine (D Rs Atg),
Dronabinol, Ondansetron (5-HT Rs Atg) / Palonosetron / Dexamethasone /
Promethazine
 Opioid induces: Metoclopramide, Prochlorperazine
 For pilots: Meclizine (long t1/2)

Constipation: tt by laxative
 Bulk-forming (Psyllium, bran, Methylcellulose): with 250 ml water to prevent
esophageal obstruction
C.I: GIT mechanical obstruction or fluid restriction / 2hrs away from food
 Osmotic Laxative: Glycerin, Lactulose
C.I: pts on galactose free diet .
 Saline laxatives:
Mg hydroxide (Milk of magnesia)
C.I: pts with cardiac or renal dis.
Interfere with absorption of Fe & Folic acid
Mg sulfate (Epsom salt) / Na phosphate
C.I: pregnant & lactating women
 Enema: not for < 2yrs, Na restricted pts, renal or cardiac diseases
 Stimulant laxatives:
Senna: DOC Opioid-induced, Excreted in breast milk
Bisacodyl: for long-term use for pts on H2Rs atg
Cascara sagrada: C.I: Children, Excreted in breast milk
 Castor oil: C.I: Pregnancy, Used in ER
 Stool softener: Docusate Na
 Lubricant/Emollient: Mineral oil

BEST USED FOR:

 Infants: Glycerin, Lactulose or sorbitol
 Children: Mg hydroxide, Mineral oil, Lactulose or sorbitol
 Pregnancy: Bulk-forming agents, stool softener, Osmotic, Mg hydroxide
Avoid: stimulant laxative, Mineral oil, Castor oil
 Breast feeding: Bulk-foaming agents, Osmotic / Mg sulfate, Cascara, Senna (2nd
choice)
 Cancer: stimulant laxative with enema /
 Elderly: Glycerin, Lactulose