Allergy Testing

ALLERGY TESTING
Allergic reactions are triggered by the contact, inhalation, or ingestion of a number of different
allergens. Some of the most common allergens are made up of proteins found in plants, mold, food,
venom, animal skin, and medication. Symptoms of allergic reactions range from mild irritation such as
itching, wheezing, and coughing, to life – threatening conditions related to the respiratory and
gastrointestinal organs. Serious allergic reactions are more likely to result from food, drugs, and stinging
insects. A person does not become allergic to a particular substance until after the first exposure.
However, in some cases, even trace amounts of a substance, such as peanuts or seafood in a mother’s
breast milk, can cause an allergic reaction in a subsequent exposure.
A variety of allergy tests are available for determining specific substances that trigger allergic
reactions in individuals. Allergists, also known as immunologists, are trained in selecting the types of tests
that are both safe and appropriate, depending on the suspected allergies. By using allergen extracts, tiny
amounts of commonly bothersome allergens (usually in the form of purified liquid drops), Immunologists
are often able to isolate which substances cause reactions in allergy sufferers.
One of the most common types of environmental allergy tests is the sink – prick test.
This technique involves placing small drops of potential allergen onto the skin of the forearm about one to
two inches apart, after the drops are placed on the arm, a needle is used to puncture the skin at the site
of each drop. (Though the procedure is virtually painless, this test is often done on the upper back of
children to prevent them from seeing the needle.) If an allergy is present, an allergic antibody called
immunoglobulin will activate a special cell called a mast cell. Mast cells release chemicals (also known as
mediators) that cause itching and swelling. The most common mediator is histamine. Histamine is what
causes the controlled hive known as a wheal and flare. The white wheal is the small raised surface, while
the flare is the redness that spreads out from it. In an uncontrolled allergic reaction, wheals and flares can
get much bigger and spread all over a person’s body. Results from a skin test can usually be obtained
within 20 to 30 minutes, while the reaction usually fades within a few hours.
Another test that is very similar to the skin – prick test is the intradermal allergy test. This involves
placing the allergen sample under the skin with a syringe. The intradermal test involves more risk and is
usually saved for use if the allergy persists even after a skin- prick test comes back negative. People who
have experienced serious allergic reactions called anaphylactic reactions are not advised to have these
types of tests. These allergy sufferers may be hypersensitive to even trace amount of the allergens when
they are introduced into the blood. Anaphylaxis is an allergic reaction that affects the whole body and is
potentially life threatening. Hives on the lips and throat can become severe enough to block air passage.
Anaphylactic shock occurs when enough histamine is released to cause the blood vessels to dilate and
release fluid into the tissues. This lowers blood volume and can result in heart failure.
A blood test can be performed to safely isolate over 400 different allergies, including dangerous
food and environmental allergens. The Radio Allegro Sorbant test measures specific antibodies using a
blood sample. Lge is normally found in very small amounts in blood, It is created as a defense
mechanism when it senses an intruder. Separate tests are done for each potential allergen and lde results
are graded from 0 to 6. For example, canine serum lge will be high if a person has an allergy to dogs. The
RAST is used if patients have pre-existing skin conditions or if patients cannot stop taking certain
medications such as antidepressants or antihistamines for even a short period of time. (People must stop
taking antihistamines several days prior to taking a skin allergy test because the medication can interfere
with the results.) The RAST is a more expensive test that does not provide immediate results.
A number of other allergy tests are available, though many are considered unreliable according to
The Academy of Allergy, Asthma, and Immunology. Applied kinesiology is a test that analyses the loss of
muscle strength in the presence of potential allergens. Provocation and neutralization testing involves
injecting food allergens into the skin in different quantities, with the goal of determining the smallest dose
needed to neutralize the symptoms. Sublingual provocation and neutralization is a similar test, expect
that the allergens are injected underneath the tongue. Cytotoxity testing involves watching for the reaction
of blood cells after placing allergens on a slide next to a person’s blood samples.
After using a reliable testing method, the cause of an allergic reaction is often identified, and a
physician is able to help a patient develop a treatment plan with the goal of controlling or eliminating the
allergic symptoms. Those who are allergic to furry pets, pollen, and plants are prescribed mild medication
or taught how to control their reactions with simple lifestyle changes, while those with food allergies learn
to safely remove certain foods from their diets. Allergy sufferers who are prone to anaphylactic reactions
are educated about life-saving techniques such as carrying the drug epinephrine and wearing medical
alert bracelets. As soon as people understand their allergies, they can begin to experience an improved
quality of life.

Allergy Testing

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ALLERGY TESTING

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