M. SC Bro. Final 20-21

University of Mumbai
DEPARTMENT OF CHEMISTRY
(AUTONOMOUS)
INFORMATION BROCHURE
FOR M. Sc. AND Ph. D. DEGREE PROGRAMMES
IN CHEMISTRY
DEPARTMENT OF CHEMISTRY
UNIVERSITY OF MUMBAI
VIDYANAGARI
SANTACRUZ (E)
MUMBAI – 400 098
Website: http://mu.ac.in/portal/distance-open-learning/faculty/department-of-chemistry/
Tel: +91(022) 2654 3353

FAX: +91(022) 2652 8547
(E-mail: chem.office@chem.mu.ac.in)
2020-2021
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CONTENTS
1. Department Profile
2. Location
3. Laboratories
4. Library
5. Hostel Accommodation
6. Financial assistance
7. Faculty
8. M. Sc. Choice-Based Credit System
9. Syllabus for M.Sc. Choice-Based Credit
System Course
10. Career Opportunities in Chemistry
11. Important Circulars
12. Information about Availability of Seats
13. Instructions to Applicants
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DEPARTMENT OF CHEMISTRY (AUTONOMOUS)
1. A PROFILE
The University Department of Chemistry, University of Mumbai, established in the year
1967, conducts Choice Based Credit System (CBCS) 4-SEMESTER- courses in Physical,
Inorganic, Organic and Analytical Chemistry, leading to the award of M. Sc. degree of the
Department of Chemistry, University of Mumbai. In addition, it also conducts program
leading to Ph. D. degree. The Department is a receipientof DST-FIST and UGC-SAP grants.
TheDepartment has been conferred autonomous status from the academic year 2009-10.
Since inception of the department, over 2000 students have taken their Master‟s degree by
papers; more than 250 students have been awarded doctorates, and more than 150 students
have taken their M. Sc. Degree by research. Under the M. Phil. programme, 50 teachers from
affiliated colleges have received their degrees.After autonomy of the department, over 381
students have taken their Master‟s degree by papers; more than 93 students have been
awarded doctorates, and more than 16 students have taken their M. Sc. Degree by research. It
is indeed a pleasure to report that alumni of the department are holding key positions in the
industry and academic institutions.
The Department is actively engaged in organizing Refresher Courses for college teachers
sponsored by U.G.C. and the State Government. It also conducts workshops for teachers for
effective, smooth teaching and uniformity in the implementation of the revised syllabi from
time to time. The Department has organized several National and International conferences.In
addition, the Department along with other reputed institutes and registered societies jointly
organizes lectures, workshops and research scholars' meet, science day etc. for the benefit of
teachers and students. The Department also offers consultancy services to the industry,
whenever solicited.
A Post-graduate institution is judged not only by maintenance of high teaching standards, but
also by its focus on research activity. Though plagued by problems of infrastructure in terms
of senior academic positions, the Department has consistently endeavored to raise its
standards. The Department runs projects received from the various national funding agencies
such as UGC, DST, CSIR, DAE etc. and also from the Industries. It is heartening to point out
that members of the faculty have been receiving appreciative comments on their research
articles/reviews in standard journals.
2. LOCATION
The Department is housed in Lokmanya Tilak Bhavan and the ground floor of Sant
Dnyaneshwar Bhavan in the Vidyanagari campus of the University of Mumbai. The
Vidyanagari Campus is accessible from both the Central Railway (Kurla) and Western
Railway (Santacruz) by the BEST Bus routes. The bus route Nos. 313 and 318 plying
between Santacruz (East) and Kurla (West) pass via Vidyanagari. Additionally route Nos. 37
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(between Kurla & J. M. Mehta Marg), 181 (between Seepz-Wadala), 213 (between Santacruz
- Pr. Thakre Udyan), 306 (between Santacruz - Mulund). 312 (between Seepz & Pratiksha
Nagar), 449 (between Dharavi Depot & Kandivali Bus St.-East) pass via Vidyanagari.
3. LABORATORY FACILITIES FOR PAPER AND RESEARCH STUDENTS

There are four M. Sc. Paper Laboratories well equipped with the necessary instruments/
infrastructure to perform experiments in Analytical, Inorganic, Organic and Physical
Chemistry.
All the research students are comfortably accommodated in the various research laboratories.
There is a computer laboratory equipped with twelve computers with internet connection.
The Department is well equipped with the necessary infrastructure and sophisticated
instruments. A 300 MHz NMR and CHN analyzer have been procured through the DST-FIST
program. GC-MS instrument has been procured through UGC-SAP program. In addition, the
department has FTIR, UV-Visible spectrophotometers, Spectrofluorimeter, HPLC, GC,
Digital Polarimeter, Ion meters, Electro-chemical workstations, CVD, Catalytic
Hydrogenator, Microwave Oven, Auto-titrator, Ultrasonic reactors, TG/DTA, AAS,
GPCandXRD. The department has also acquired new technological devices such as Audio-
Visual system, LCD Projector, E-Beam System, Media Imager and Visual Presenter. Internet
access is provided to the staff and research as well as paper students.
The Department has a seminar room with seating capacity of 60.
4. LIBRARY
The Department has its own library on the ground floor of Sant Dnyaneshwar Bhavan. In
addition, Jawaharlal Nehru Library, which is a central library at the Vidyanagari campus, is
well equipped with books, journals, periodicals and Encyclopedias of Chemistry. There is a
separate facility for carrying out literature survey. The students enrolled in the Department
can avail of reading as well as lending facilities.
5. HOSTEL ACCOMODATION FOR STUDENTS

Hostel rooms will be allotted as per the University rules.
6. FINANCIAL ASSISTANCE
A) M. Sc. By Papers- As per the rules of University of Mumbai, Mumbai and
Government on merit basis (if applicable)
B) Ph.D: NIL
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7. DEPARTMENT FACULTIES
NAME: Dr. (Smt.) Manjusha Karve

(Professor & Head- Analytical)
PAPERS 30 Ph. D STUDENTS 02

PUBLISHED: GUIDED:
M.Sc STUDENTS 06 RESEARCH 01
GUIDED (by research) PROJECTS
COMPLETED:
RESEARCH Solvent Extraction, Solid phase Extraction, Environmental
INTERESTS Analysis.
NAME: Dr. Shivram S. Garje

(Professor-Inorganic)
PAPERS 62 Ph. D STUDENTS 08 (completed)

PUBLISHED: GUIDED: 05 (ongoing)
Patents: 01 Consultancy -
projects
M.Sc STUDENTS 05 RESEARCH 02 (completed)
GUIDED (by research) PROJECTS 01(ongoing)
COMPLETED:
RESEARCH Materials Chemistry, Organometallics, Nanomaterials,
INTERESTS Development of molecular precursors for nanomaterials
and thin films, Nanocomposites and their applications
Honors/Awards  BOYSCAST Fellowship, DST
 Performance based Incentive Award, University of
Mumbai.
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NAME: Dr. Navinchandra G. Shimpi
(Associate Professor-Physical)

Patents 04 Consultancy 01(completed)
projects
M.Tech STUDENTS 15 RESEARCH 09 (completed)
GUIDED: PROJECTS 02 (ongoing)
COMPLETED:
RESEARCH Synthesis of nanomaterials, Conducting polymers,
INTERESTS Biodegradable polymer nanocomposites, Gas sensing
materials, Organic transformation reactions, Dye
degradation and Shape memory polymers
Honors/Awards  AICTE Career Award for Young Teachers (CAYT).
 Young Scientist Award by APA, IIT, New Delhi
(International)
 Fellow – Maharashtra Academy of Science
 Dyanjoti Puraskar,Shirsathe Foundation, Jalgaon
NAME: Dr. Rajesh M. Kamble

(Associate Professor-Analytical)

Patents - Consultancy -
projects
COMPLETED:
RESEARCH Design, Synthesis and characterization of novel AIE and
INTERESTS TADF functional organic materials for applications in
Organic Light Emitting Devices (OLEDs), Solar cells, as
Chemosensors and for Bio-imaging purpose.
Honors/Awards -
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NAME: Dr. Vishwanath R. Patil
(Associate Professor-Physical)
PAPERS 48 Ph. D STUDENTS 16(completed)

Patents 33 Consultancy 01 (ongoing)
projects
GUIDED (by research) PROJECTS 01 (ongoing)
COMPLETED:
RESEARCH Design, Synthesis and characterization of novel AIE
INTERESTS functional organic materials for applications in Organic
Light Emitting Devices (OLEDs), Bio-imaging and Solar
cells.
Honors/Awards  Prof. B. C. Haldar Memorial Research Award
 Best Researcher & Academician Award (Bionano
Frontier & University of Mauritius)
NAME: Dr. Suresh D. Pawar

(Associate Professor-Inorganic)
PAPERS 28 Ph. D STUDENTS 08 (ongoing)

PUBLISHED: GUIDED:
projects
M.Sc STUDENTS - RESEARCH -
COMPLETED:
RESEARCH Solvent extraction, Coordination Chemistry,
INTERESTS Nanomaterials, and Metallo organic framework.
Honors/Awards -
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NAME: Dr. Shilpee Sachar
(Assistant Professor- Inorganic)

PUBLISHED: GUIDED:
projects
M.Sc STUDENTS - RESEARCH -
COMPLETED:
RESEARCH Solubility and stability properties of therapeutic drugs in
INTERESTS the pre-formulation stage by complexing with different
surface active agents,Surface modifications of
nanoparticles,Colloidal Chemistry and its applications, e.g.
in nanotechnology and bio-medical field.
Honors/Awards -
NAME: Dr. Purav M. Badani

(Assistant Professor-Physical)

PUBLISHED: GUIDED:
Patents - Consultancy 01(completed)
projects
M.Sc STUDENTS 04 RESEARCH 01(completed)
COMPLETED:
RESEARCH Molecular modeling, reaction dynamics and non-covalent
INTERESTS interactions.
Honors/Awards -
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NAME: Ramchandra G. Thorat
(Assistant Professor-Organic)
PAPERS PUBLISHED: - Ph. D STUDENTS -

GUIDED:
Patents - Consultancy projects -
M.Sc STUDENTS - RESEARCH PROJECTS -
GUIDED (by research) COMPLETED:
RESEARCH INTERESTS Synthetic Organic Chemistry
Honors/Awards -
NAME: Bhushan B. Popatkar

(Assistant Professor-Analytical)
PAPERS 02 Ph. D STUDENTS -

PUBLISHED: GUIDED:
Patents - Consultancy projects -
M.Sc STUDENTS - RESEARCH PROJECTS -
GUIDED (by research) COMPLETED:
RESEARCH Green chemistry, Development of new methods for the
INTERESTS synthesis of heterocyclic compounds, water analysis
Honors/Awards -
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NAME: Dr. Sudesh T. Manjare
(Assistant Professor-Inorganic)
PAPERS PUBLISHED: 21 Ph. D STUDENTS 05 (ongoing)

GUIDED:
Patents 01 Consultancy projects -
M.Sc STUDENTS GUIDED - RESEARCH 03 (Completed)
(by research) PROJECTS
COMPLETED:
RESEARCH INTERESTS Synthesis and Bio-applications of Chalcogen-based
Small Molecular Probes, Synthesis of
Organometallic Compounds, Metal Complexes and
Their Applications in Organic Synthesis, Material
Science and for Energy Conversion.
Honors/Awards Post-doctoral Research Fellow from Institute for Basic
Science in Korea Advanced Institute of Science and
Technology (KAIST), Daejeon, South Korea.
NAME: Dr. Arun K. Kadu

(Assistant Professor-Physical)

PUBLISHED: GUIDED:
projects
M.Sc STUDENTS - RESEARCH 01 (Ongoing)
COMPLETED:
RESEARCH Electrochemistry: Development of sensors,
INTERESTS nano-composites for sensors and catalyst.
Honors/Awards -
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NAME: Dr. Anil V. Karnik
(Professor-Organic, UGC-BSR Fellow)
PAPERS PUBLISHED: 41 Ph. D STUDENTS 15 (completed)

GUIDED: 06 (ongoing)
Patents 01 Consultancy 01 (Completed)
projects
M.Sc STUDENTS 16 RESEARCH -
COMPLETED:
RESEARCH Chiral Chemistry, Synthetic Organic Chemistry, Heterocyclic
INTERESTS Chemistry.
 Honors/Awards  Performance based Incentive award, University of

Mumbai.
 Elected Fellow of Maharashtra Academy of Science
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M.Sc ALL BRANCHES TOPPERS- 2016-17 SET QUALIFIED STUDENTS-2016-18
1.Ms. Ansari Sabrin (Physical Chemistry; 7.16 CGPA) 1.Ms. Poornima Acharya
2.Ms. Shaikh Nilofer (Inorganic Chemistry; 7.57 CGPA) 2.Mr. Divyesh Shelar
3.Ms. Pooja Zanje (Organic Chemistry; 8.86 CGPA) 3.Ms. Rajashree Prajapati
4.Mr. Kisan Gupta (Analytical Chemistry; 8.39 CGPA) 4.Mr. Sarfraz Shaikh
M.Sc ALL BRANCHES TOPPERS- 2018-19 5.Mr. Jatin Lade
6.Mr. Sachin Golhe
1. Ms. Jain Hansakumari Suresh Sushila (Physical
Chemistry; 7.72 CGPA)
7.Ms. Shaikh Aksh Hina
2. Ms. Khan Zuha Firoz Gulnaz (Inorganic Chemistry; 8.41 8.Mr. Mangesh Pingale
CGPA) 9.Mr. Amit Surve
3.Ms. Shinde Rupali Dasharath Darshani (Organic 10.Ms. Ashvini Jadhav
Chemistry; 8.88CGPA) 11.Kishan Gupta
4.Ms. Naik Pragati Anil Anita (Analytical Chemistry; 7.91 12.Madan Birajdar
CGPA)
13.Nitin Gulvi
GATE QUALIFIED STUDENTS-2016-18
14.Prakash Aaraj
1.Mr. Divyesh Shelar
15.Rakesh Raigawali
2.Madan Birajdar
16.Suhas Salunkhe
3.Pooja Singh
17.Ms. Pooja Singh
4.Rakesh Raigawali
18.Girish Kadam
NET-LECTURERSHIP QUALIFIED STUDENTS- 19.Anju Ashokan
2016-18
1.Mr. Ganesh Pavale SET QUALIFIED STUDENTS-2019-20
2.Mr. Aleem Ansari 1. Ms. Manisha Patel
3.Mr. Rupesh Mestri 2. Ms. Divya Mahatre
4.Ms. Poornima Acharya
5.Madan Birajdar
6.Rakesh Raigawali
7.Pooja Singh
8.Sampat Shingada
NET-LECTURERSHIP QUALIFIED STUDENTS- NET-JRF QUALIFIED STUDENTS-
2019-20 2016-18
1.Ms. Manisha Patel 1.Mr. Siddharth Kamble
2.Ms. Rupali Shinde 2.Mr. Navin Yadav
3.Ms. PrajaktaPise 3.Mr. Sachin Dhodi
4.Mr. Ega Sai Prasad Somashekar
5.Madan Birajdar
6.Rakesh Raigawali
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8. M. Sc. CHOICE-BASED CREDIT SYSTEM (CBCS)
The Choice-Based Credit System (CBCS) has been introduced for the Master‟s Program from
the Academic Year 2016-17. A minimum of 96 credits have to be earned by students across
four Semesters. Semesters I and II form the First year of the M. Sc. programme and comprise
the courses from four branches while Semesters III and IV are in the second year of the M.
Sc. programme in the respective specialization chosen by the student at the time of admission
to the M. Sc. Course.
The Salient features of Choice-Based Credit System (CBCS) are as follows:
Credit: One credit shall be equal to one hour teaching per week per semester for 15 weeks.
M. Sc. Course:
M. Sc. Course shall be given four teaching hours per week per paper. Each paper shall
have 4 credits.
There shall be four papers of 4 credits each per semester.
Thus there shall be 16 theory lectures per week.
There shall be 8 credit practical components for M. Sc.
Two hours of laboratory component per week shall be considered as 1 credit. Thus,
students shall perform 16 hours of practical per week per semester for 15 weeks.
M. Sc. Program: M. Sc. Program shall consist of 96 credits over four semesters.
Courses: There shall be four types of courses:
(i) Core Courses
(ii) Elective Courses
(iii) Optional Courses
Core Courses: Core-courses shall be offered by parent department.
 Core courses being the absolute necessity for a master‟s degree in a subject, shall be
never less than 75% for any of the semesters.
 Semester I & II shall have 100% core courses.
 Semester III & IV shall have three theory papers (12 credits) each on core courses.
 Semester III shall have 8 credits of practical component. Students shall perform 16
hours of practical per week for 10-15 weeks.
 Semester IV shall have 8 credits of Project component. For this, students shall
perform 8 hours per week practical work for 10-15 weeks.
Elective Courses:
 Elective Courses shall be offered by parent departments in semester III and each
course will be of 4 credits.
Optional Courses:
Optional Courses shall be offered by parent departments in semester IV and
each course will be of 4 credits.
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Choice-Based Courses:
It shall be made mandatory to offer two Elective courses in the third semester
and 2 Optional Courses [OC1 & OC2] in the fourth semester.
The Optional course shall be interdisciplinary in nature.
Each department shall offer 2 Optional courses for the benefit of students from
other disciplines. There shall be a total of 4 lectures required per week for
optional courses. There shall be a fixed slot for this component where
lectures from core courses and Elective courses shall not be held.
The Head of the Department shall communicate the internal marks for OC1 and
or OC2 for the students from other departments to the head of their parent
department. The internal marks for all the courses shall be communicated to
the COE by the parent departments only.
The structure:
Semester I: Theory papers of 4 credits each only on core subject.
8 credits for practical component.
Semester II: Theory papers of 4 credits each only on core subject.
8 credits for practical component.
Semester III: Theory papers of 4 credits each only on core subject.
One theory paper of 4 credits on 2 Elective courses. 8 credits for practical component.
Semester IV: Theory papers of 4 credits each only on core subject.
One theory paper of 4 credits on 2 Optional courses. 8 credits of Project component.
Admission to M. Sc. Choice-Based Credit System (CBCS) Course

Admission to departments where entrance examination will not be necessary, the admission
shall be decided only on the basis of T. Y. B. Sc. Norms give below:
[1] T. Y. B. Sc. Marks component for Mumbai University Students
a) The marks secured by the student, without grace marks, with as a single major
subject out of 600 (Sem V & VI) shall be considered.
b) Students securing first class and above shall be given priority over students not
securing second class at T. Y. B. Sc. examination.
c) The CGPA shall be considered if the marks are equal.
d) All things being equal, the students with first class shall be given priority over
the students who have been declared passed in First Class with grace marks/
Second Class with as a single major subject out of 600 (Sem V & VI).
e) The students offering two major subjects, “The Subject Applied for Master‟s
Degree” as one of the subject at T. Y. B. Sc. be admitted in order of merit by
considering marks secured in “The Subject Applied for Master‟s Degree” at
only.
f)In case of there is a tie in (a), (b), (c), (d) or (e), aggregate marks without grace
marks out of 600 shall be considered.
g) In case of there is a tie in (a), (b), (c), (d) or (e), then all students tied at the rank
shall be admitted.
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The final merit list will be displayed on the website of the University and also on the Notice
Board of the Department.
[2]For other University students:
Marks declared by the concerned University at T. Y. B. Sc. Examination and as
shown in mark sheet “The Subject Applied for Master‟s Degree” will be considered
for preparing the merit list as per quota available for other University students.
Marksheet of F.Y to T.Y. B.Sc must be attached alongwith the form.
Examination
All examinations for all semesters are conducted by the respective departments for the
students admitted in the departments.
The examinations shall be of two kinds:
I.Internal assessment II. End Semester Examination
Internal Assessment: The internal assessment for theory papers shall be for 40% marks.
End-Semester Examination: The end semester assessment shall be for 60% marks for
theory papers and 100% for practical examination.
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9. SYLLABI FOR M. Sc. CHOICE BASED CREDIT SYSTEM (CBCS) FOUR-
SEMESTER-COURSE IN CHEMISTRY
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SEMESTER-I
No. of Examination
No. of hours per Mid End- Total
Course
Title of the Course Credits SEMESTE Sem Sem Marks
Code -R Marks Marks
CHEM
Physical Chemistry I 4 60 40 60 100
101
CHEM
Inorganic Chemistry I 4 60 40 60 100
102
CHEM
Organic Chemistry I 4 60 40 60 100
103
CHEM
Analytical Chemistry I 4 60 40 60 100
104
CHEM Physical Chemistry
2 - - 50 50
105 Practical I
CHEM Inorganic Chemistry
2 - - 50 50
106 Practical I
CHEM Organic Chemistry
2 - - 50 50
107 Practical I
CHEM Analytical Chemistry
2 - - 50 50
108 Practical I
Total 24 Total 600
* Practical component involves 16 h per week laboratory work for 15 weeks.
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SYLLABUS: SEMESTER-I
CHEM 101: PHYSICAL CHEMISTRY-I
Unit-I THERMODYNAMICS-I [15L]
State function, exact and inexact differentials, Internal energy, Enthalpy, Heat capacity,
Relation between Cp and Cv, Limitations of first law of thermodynamics, Joule-Thomson
experiment, Joule-Thomson coefficient, Joule-Thomson coefficient for real and an ideal gas,
Inversion temperature
Absolute temperature, Spontaneous or irreversible process, Entropy, Thermodynamic
equation of state, Maxwell relation, Helmholtz and Gibbs free energy, Third law of
thermodynamics, Nernst heat theorem, Determination of absolute entropies, entropy changes
in chemical reaction, residual entropy.
Unit-II FUNDAMENTAL ASPECTS OF QUANTUM CHEMISTRY [15L]
Introduction: Historical background, Old Vs New Quantum Theory, Heisenberg‟s
Uncertainty Principle, The wave nature of matter
Fundamental Background:Postulates of Quantum Chemistry, Commutators of operators,
Properties of Linear and Hermitian operators, Operators for the dynamic variables of a
system such as position, linear momentum, angular momentum and total energy,
Expectation Value,
Progressive and standing waves, Conditions on the wave function and its interpretation,
Normalization and orthogonality, Separation of variables, Obtaining Schrödinger‟s time
independent wave equation from Schrödinger‟s time dependent wave equation.
Application of Quantum Chemistry in Translation motion: Particle in one dimension
box: Differential equation and its solution, Graphical representation of wavefunctions and
probability densities, Normalization and orthogonality of wave functions. Even and Odd
Functions.
Particle in a two and three dimensional box: Differential equation and its solution,
Degeneracy, Energy level Diagram.
Unit-III PHASE RULE AND ITS APPLICATIONS [15L]
Phase rule, Phase diagrams and their classification, Lambda transitions.
Two component system: Vapor pressure – composition diagrams, Phase diagrams for
partially miscible liquids for two components, Critical solution temperature, influence of
foreign substances on CST, fractional distillation of Zeotropic and Azeotropic mixtures.
Three component systems:
Type I-Formation of one pair of partially miscible liquids: Graphical representations, binodal
curves, plait point, influence of temperature-System showing real critical solution
temperature, System showing no real critical solution temperature.
Type II-Formation of two pairs of partially miscible liquids.
Type III-Formation of three pairs of partially miscible liquids, Influence of impurities,
Ternary Azeotropic mixtures, Preparation of absolute alcohol by azeotropic elimination of
water.
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Unit-IV CHEMICAL KINETICS [15L]
Accounting for the rate laws: simple reactions, temperature dependence of reaction rates,
consecutive reactions,(rate determining step approximation and steady-state approximation),
unimolecular reactions – Lindemann-Hinshelwood mechanism.
Kinetics of complex reactions - Chain reactions, polymerization reactions, explosions,
photochemical reactions.
Fast reactions: Study of kinetics by flow methods, relaxation methods, flash photolysis,
magnetic resonance method, shock tube method.

Derivation not expected
Note: Numerical and theoretical problems from each Unit- are expected.
References books:
1. Peter Atkins and Julio de Paula, Atkin’s Physical Chemistry, 7th ed., Oxford
University Press, 2002.
2. K. J. Laidler and J. H. Meiser, Physical Chemistry, 2nd ed., CBS Publishers and
Distributors, New Delhi, 1999.
3. Robert J. Silby and Robert A. Alberty, Physical Chemistry, 3rd ed., John Wiley and
Sons (Asia) Pte. Ltd., 2002.
4. Ira R. Levine, Physical Chemistry, 5th ed., Tata McGraw-Hill, New Delhi, 2002.
5. G. W. Castellan, Physical Chemistry, 3rd ed., Narosa Publishing House, New Delhi,
1983.
6. D. A. McQuarrie and J. D. Simon, Physical Chemistry - a molecular approach, Viva
Books Private Limited, New Delhi, 1998.
7. S. Glasstone, Text Book of Physical Chemistry, 2nd ed., McMillan and Co. Ltd.,
London, 1962.
8. D. A. McQuarrie, Quantum Chemistry, Viva Books Private Limited, New Delhi, first
Indian ed., 2003.
9. B. K. Sen, Quantum Chemistry including spectroscopy, Kalyani Publishers, 2003.
10. A. K. Chandra, Introductory Quantum Chemistry, Tata Mc Graw-Hill, 1994.
11. R. K. Prasad, Quantum Chemistry, 2nd ed., New Age International Publishers, 2000.
12. D. O. Hayward, Quantum Mechanics for Chemists, Royal Society for Chemists, 2002.
13. Sydney T. Bowden, The phase rule and the phase reaction, McMillan and Co. Ltd.,
London, 1938.
14. A. N. Cambell, Alexander Findlay, The Phase Rule and its Applications, Dover
publications.
15. G. L. Agarwal, Basics Chemical kinetics, Tata Mcgraw Hill, New Delhi.
16. K. J. Laidler, Chemical Kinetics, 3rd ed., Pearson Education.
17. R. P. Rastogi, R. R. Mishra, An Introduction to Chemical Thermodynamics, Vikas
Publishing House Pvt. Ltd.
List of Books for further reading:

1. S. Glasstone, Thermodynamics for Chemists, Affiliated East-West Press, New Delhi,
1964.
2. W. G. Davis, Introduction to Chemical Thermodynamics – A Non-Calculus Approach,
Saunders, Philadelphia, 1972.
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3. I. M. Klotz and R. M. Rosenberg, Chemical Thermodynamics, 5th ed., John Wiley and
Sons, Inc., 1994.
4. Peter A. Rock, Chemical Thermodynamics, University Science Books, Oxford
5. Ira N. Levine, Quantum Chemistry, 5th ed., Pearson Education (Singapore) Pte. Ltd.,
Indian Branch, New Delhi, 2000.
6. J. P. Lowe, Quantum Chemistry, 2nd ed., Academic Press, New York, 1993.
7. R. Anantharaman, Fundamentals of Quantum Chemistry, McMillan India Limited,
2001.
8. Mahendra R. Awode, Quantum Chemistry, S. Chand and Co. Ltd., New Delhi, 2002.
CHEM-102: INORGANIC CHEMISTRY-I

Unit-I INORGANIC REACTION MECHANISMS [15L]
(i)Rate of reactions, factors affecting the rate of reactions; techniques for the
determination of rate of reactions.
(ii) Mechanisms and factors affecting the (I) ligand substitution reactions of (a)
octahedral complexes with and without breaking of metal-ligand bond, (b)
square planar complexes – trans-effect, its theories and applications and (c)
tetrahedral complexes; (II) Redox reactions: inner and outer sphere
mechanisms.
(iii) Complimentary and non-complimentary reactions.
(iv) Isomerization and racemization reactions.
Unit--II ORGANOMETALLIC CHEMISTRY [15L]
(i) Recapitulation of classification of organometallic compounds, electron
counting and eighteen electron rule.
(ii)Sixteen electron rule.
(iii)Synthesis, structure and bonding of the following organometallic
compounds:
(a) Alkyl and Aryl derivatives, (b) Carbenes and Carbynes, (c) Alkene
complexes, (d) Alkyne complexes, (e) Allyl complexes, (f)
Cyclopentadiene complexes and (g) Arene complexes (sandwich and half
sandwich complexes).
Unit-III CHEMICAL BONDING [15L]
(i)Hybridization: Derivation of wave functions for the following orbital
hybridisation types: sp (BeH2); sp2 (BF3); sp3 (CH4) considering only
sigma bonding.
(ii)Molecular Orbital Theory (LCAO-MO approach) for Electron deficient and
Electron rich species.
(iii) Hydrogen bonding: concept, types, properties, methods of detection and
importance. Van der Waal‟s forces, ion-dipole, dipole-dipole, London
forces.
(iv)Bent‟s Rule: Reactivity of molecules: e.g. chlorofluorides of phosphorous,
fluoromethanes, etc.
Unit-IV CHEMICAL REACTIVITY [15L]
(i) Hydration of cations and anions, Latimer equations, acidity of cations and
oxocations, basicity of anions and oxoanions, classification of mono and
polyatomic ions on the basis of pKa with predominance diagram.
Classification of oxoacids, structural anomalies.
(ii)Recapitulation of hard soft acids and bases (HSAB) principle, Acid-base
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strength and softness and hardness; Classification of Lewis acids and bases
based on frontier Molecular orbital topology, Reactivity matrix of Lewis
acids and bases; Superacids and bases.
(iii)Redox properties of the elements:
Latimer diagram: Construction of the diagram, non-adjacent species and
disproportination.
Frost Diagram: Construction and interpretation.
Pourbaix diagram of Iron in natural water.
Reference books:
Unit-I
1. D. Banerjea, Coordination Chemistry, Tata McGraw Hill, 1993.
2. F. Basalo and R. G. Pearson, Mechanism of Inorganic Reactions, 2ndEd., Wiley, 1967.
3. M. L. Tobe and J. Burgess, Inorganic Reaction Mechanism, Longman, 1999.
4. P. Atkins, T. Overton, J. Rourke, M. Weller and F. Armstrong, Inorganic Chemistry,
5thEd., Oxford University Press, 2010.
5. R. Gopalan and V. Ramlingam, Concise Coordination chemistry, Vikas Publishing
house Pvt Ltd., 2001
Unit-II
1. R. H. Crabtree, The Organometallic Chemistry of the Transition Metals, 5thEd., Wiley
Interscience, 2009.
2. R. C. Mehrotra and A. Singh, Organometallic Chemistry-A Unified Approach, 2ndEd.,
New Age International Pvt. Ltd., 2000.
3. G. O. Spessard and G. L.Miessler, Organometallic Chemistry, Prentice-Hall, 1977.
4. K. F. Purcell and J. C. Klotz, Inorganic Chemistry, Saunders, 1977.
5. B. Douglas, D. H. McDaniel and J. J. Alexander, Concepts and Models of Inorganic
Chemistry, 2nd Ed., John Wiley & Sons, 1983.
6. J. Huheey, F. A. Keiter and R. I. Keiter, Inorganic Chemistry – Principles of Structure
and Reactivity, 4th Ed., Harper Collins, 1993.
Unit-III
2. P. J. Durrant and B. Durrant, Introduction to Advanced Inorganic Chemistry, Oxford
3. R. L. Dekock and H.B.Gray, Chemical Structure and Bonding, The
BenjaminCummings Publishing Company, 1989.
4. K. L. Kapoor, A textbook of Physical Chemistry, Volume 4, McMillan, 2001.
5. G. Miessler and D. Tarr, Inorganic Chemistry, 3rd Ed., Pearson Education, 2004.
6. R. Sarkar, General and Inorganic Chemistry, Books & Allied (P) Ltd., 2001.
7. C. M. Day and J. Selbin, Theoretical Inorganic Chemistry, Affiliated East West Press
Pvt. Ltd., 1985.
8. J. N. Murrell, S. F. A. Kettle and J. M. Tedder, The Chemical Bond, Wiley, 1978.
9. G. A. Jeffrey, An Introduction to Hydrogen Bonding, Oxford University Press, Inc.,
21
1997.
10. W. W. Porterfield, Inorganic Chemistry-A Unified Approach, 2nd Ed., Academic Press,
1993.
11. B. W. Pfennig, Principles of Inorganic Chemistry, Wiley, 2015.
Unit-IV
1. G. Wulfsberg, Inorganic Chemistry, Viva Books Pvt. Ltd., 2002.
2. B. Douglas, D. McDaniel and J. Alexander, Concepts and Models of Inorganic
Chemistry, 3rdEd., John Wiley & Sons, Inc., 2001.
3. P. Atkins, T. Overton, J. Rourke, M. Weller and F. Armstrong, Inorganic Chemistry,
5thEd., Oxford University Press, 2010.
4. G. Miessler and D. Tarr, Inorganic Chemistry, 3rd Ed., Pearson Education, 2004.
5. B. W. Pfennig, Principles of Inorganic Chemistry, Wiley, 2015.
7. R. L. Madan and G. D. Tuli, Inorganic Chemistry,5th Ed., S. Chand, 2012.
8.. J. D. Lee, Concise Inorganic Chemistry, 5th Ed., Wiley, 2012.
9. B. R. Puri, L. R. Sharma and K. C. Kalia, Principles of Inorganic Chemistry, Milestone,
2014.
10. http://www.meta-synthesis.com/webbook.html
CHEM 103: ORGANIC CHEMISTRY-I

Unit-IPHYSICAL ORGANIC CHEMISTRY [15L]
1.1Acidity-Basicity:
Different concepts and examples, Factors affecting acidity & basicity. Electrophilicity
and Nucleophilicity; Ambident Electrophiles and Nucleophiles, Relationship between
nucleophilicity and basicity.
1.2Non-kinetic Methods of determining reaction mechanism:
Product profiles, Detection and identification of intermediates by chemical/trapping and
spectroscopic means. Evidence from catalysis, cross-over experiments, isotopic labeling,
Kinetic isotope effect-primary & secondary isotope effect, Stereochemical studies.
1.3Linear Free Energy Relationships:
Effect of structure on reactivity, Hammett equation, substituent and reaction
constants,Through conjugative effects of substituents, Linear free energy relationships in
the determination of reaction mechanism,Taft Equation, steric parameter.
Unit-II STEREOCHEMISTRY [15L]
2.1: Symmertry operations and symmetry elements:
Symmetry Operations, identification of principal axis, symmetry elements, definition and
examples of molecules with different elements of symmetry including σv, σhσd
2.2 Molecules with tri and tetracoordinate chiral centres:
Compounds with carbon, silicon, nitrogen, phosphorous and sulphur chiral centres and their
relative configurational stabilities.
2.3 Molecules with two or more chiral centres:
22
Configurational nomenclature, Constitutionally unsymmetrical molecules: Erythro-threo and
syn-anti systems. Constitutionally symmetrical molecules with odd and even number of
chiral centres: enantiomeric and meso forms, concept of stereogenic, chirotopic and
pseudoasymmetric centres.
2.4 Axial and Planar chirality:

Principles of axial, planar and helical chirality, Stereochemical features and configurational
descriptors (R,S) for the following classes of compounds: allenes, alkylidene
cycloalkanes, spiranes, biaryls (including BINOLs and BINAPs), ansa compounds,
cyclophanes and helicenes.
2.5 Prochirality:
Concept of prochirality, homotopic enatiotopic, and distereotopic ligand and faces: criteria
based on symmetry and substitution/addition of molecules with different elements of
chirality. Notation of prochirality, notation for molecules with pro-pseudo asymmetric
centres. Notation for molecules with presence of a chiral and a pro-chiral centres. Top-
right mnemonic.
Unit-III METHODS OF C-C BOND FORMATION USING THE CARBONYL
FUNCTON [15L]
3.1 Reactivity of carbonyl group, Enols and enolates- Regioselective kinetic and
thermodynamic enolate formation using LDA. Different types of aldol condensations
under acid and base catalysis.
3.2 Generation of dianion derived from active methylene compounds and regioselective C-C
bond formation on unstabilized site.
3.3 Mechanism, stereochemistry and applications of the following reactions: Acyloin,
Benzoin, Claisen, Darzen, Dieckmann, Knoevenagel, Mannich, Michael, Robinson
Annulation and Stobbe.
3.4 Enamines as enolate equivalents. Metalloenamines, Synthesis of enamines and selected
C-C bond formation.
Unit- IVSPECTROSCOPY [15L]
4.1 UV-Visible Spectroscopy:
Recapitulation of basic concepts and sample handling. Woodward-Fieser rules for
calculation of λMax of conjugated dienes, polyenes, enones and aromatic carbonyl
compounds.
Problems based on Woodward-Fieser rules.
4.2 IR Spectroscopy:
Recapitulation of basic concepts and sample handling. Group frequencies and their use in
detection and identification of functional groups.
4.3 PMR Spectroscopy:
Recapitulation of basic concepts and sample handling. Prediction of structure of organic
compounds based on the use of chemical shift and J values.
23
4.4 Mass Spectrometry:
Recapitulation of basic concepts and sample handling. Fragmentation Pattern of major
classes of organic compounds, Retro-Diels Alder reaction, McLafferty rearrangement and
ortho effect.
4.5 Structure determination of organic compounds involving individual or combined use of
the above spectral techniques.
References Books:
1.Organic Chemistry, J. Claydens, N. Greeves, S. Warren and P. Wothers, Oxford
University Press.
2.Advanced Organic Chemistry, F.A. Carey and R.J. Sundberg, Part A and B, Plenum
Press.
3.Stereochemistry: Conformation and mechamism, P.S. Kalsi, New Age International,
New Delhi.
4.Stereochemistry of carbon compounds, E.L Eliel, S.H Wilen and L.N Manden, Wiley.
5.Stereochemistry of Organic Compounds- Principles and Applications, D. Nasipuri. New
International Publishers Ltd.
6.March‟s Advanced Organic Chemistry: Reactions, Mechanisms and Structure, Michael
B. Smith, Jerry March, Wiley.
7.Advanced Organic Chemistry: Reactions and mechanism, B. Miller and R. Prasad,
Pearson Education.
8.Advanced Organic Chemistry: Reaction mechanisms, R. Bruckner, Academic Press.
9.Understanding Organic Reaction Mechanisms, Adams Jacobs, Cambridge University
Press.
10. Writing Reaction Mechanism in organic chemistry, A. Miller, P.H. Solomons,
Academic Press.
11. Principles of Organic Synthesis, R.O.C. Norman and J.M Coxon, Nelson Thornes.
12. Advanced Organic Chemistry: Reactions and mechanism, L.G. Wade, Jr., Maya
Shankar Singh, Pearson Education.
13. Introduction to Spectroscopy, Donald L. Pavia, Gary M. Lampman, George S. Kriz,
Thomson Brooks.
14. Spectrometric Identification of Organic Compounds, R. Silverstein, G.C Bassler and
T.C. Morrill, John Wiley and Sons.
15. Organic Spectroscopy, William Kemp, W.H. Freeman & Company.
16. Organic Spectroscopy-Principles and Applications-Jagmohan, Narosa Publication.
17. Organic Spectroscopy, V.R. Dani, Tata McGraw Hill Publishing Co.
18. Spectroscopy of Organic Compounds, P.S. Kalsi, New Age International Ltd.
19. Mechanism in Organic Chemistry, Peter sykes, 6th edition onwards.
20. Physical Organic Chemistry, Neil Isaacs
21. Modern Physical Organic Chemistry, Eric V. Anslyn and Dennis A. Dougherty
24
CHEM 104: ANALYTICAL CHEMISTRY I
Unit I: Concepts of Analytical Chemistry [15L]
1.1 Concepts of Analytical Chemistry: Classification of Analytical [2L]
Methods: An overview of Classical methods, Types of
Instrumental methods
Selection of an analytical methods and their performance [2L]
criteria.
1.2 Concepts of optical methods: Electromagnetic spectrum, [6L]
transitions, components in optical instruments, sources,
description of LASER, wavelength selectors, monochromator
functioning, effective band width, detectors and description of
diode array type detector.
1.3 Atomic Absorption Spectrometry: Principle, interferences, use of [5L]
electro thermal analyser, hydride generator and cold vapour for
trace metal analysis. Importance of electro thermal analyser for
analysis of biological samples, level of detection; hydride
generator for environmental samples and cold vapour technique
for mercury analysis.
Unit II: Atomic and molecular spectroscopy [15L]
2.1 Molecular transitions, derivative and dual wavelength [5L]
spectroscopy. Application to trace analysis (d-d transition and
charge transfer), biological samples and simultaneous
determinations.
2.2 Atomic Emission Spectroscopy based on plasma source, [5L]
advantages of plasma source. Applications in geo-analysis, metal
samples, agriculture and food samples and environmental
analysis.
2.3 Infrared spectroscopy: Concept of Fourier Transform [5L]
Spectroscopy, instrumentation, advantages of FTIR and
applications. Non-dispersive IR for detection of environmental
gases.
UNIT III: Separation methods [15L]
3.1 Solvent Extraction and Solid Phase Extraction: Recapitulation of [7L]
basic concepts of solvent extraction and solid phase extraction.
Liquid anion and cation exchangers. Mechanism of extraction.
Extraction equilibria of metal chelates. Factors favoring solvent
extraction of metal chelates. Sorbents.
3.2 Chromatography: General classification of chromatographic [8L]
methods. Concept of plate and rate theories: efficiency,
resolution, selectivity and separation capability. Broadening of
chromatographic peak and van Deemter equation. Optimization
of chromatographic conditions.
UNIT IV: Column chromatography techniques [15L]
4.1 Gas Chromatography: Principle of GLC and GSC; [4L]
Instrumentation: carrier gas supply, sample introduction systems,
packed & capillary columns; choice of detectors and
comparative account of TCD, FID, ECD & thermionic detector.
25
Temperature programming;
4.2 Applications in various fields. [3L]
4.3 High Performance Liquid Chromatography (HPLC): Types of [5L]
liquid chromatography, column efficiency in LC; Instrument for
LC: mobile phase reservoir and solvent treatment systems,
pumping systems, sample introduction systems, columns,
Detectors: UV, RI, EC and diode array. Modes of separation:
partition, adsorption, ion exchange and size exclusion.
4.4 Applications in various fields. [3L]
Texts/ References:
1. D. A. Skoog, F. J. Holler, and T. A. Nieman, Principles of Instrumental Analysis, 5th ed.,
Philadelphia: Saunders College Publishing, 1998.
2. D. A. Skoog, D. M. West, F. J. Holler and S. R. Crouch, Fundamentals of Analytical
Chemistry, 8th ed., Philadelphia: Saunders College Publishing, 2004.
3. G. D. Christian, Analytical Chemistry, 6th ed., John Wiley and Sons, New York, 2003.
4. G. H. Jeffery, J. Bassett, J. Mendham and R. C. Denney, Vogel’s Textbook of Quantitative
Chemical Analysis, 6th ed., ELBS, Longman Scientific & Technical, England, 2002.
5. H. H. Willard, L. L. Merrit, jr., J. A. Dean and F. A. Settle, Jr., Instrumental Methods of
Analysis, 6th ed., CBS 1986.
6. R. D. Braun, Introduction to Instrumental Analysis, McGraw Hill, 1987.
7. G. H. Morrison and H. Freiser, Solvent Extraction in Analytical Chemistry, John Wiley &
Sons, New York, 1966.
8. S. M. Khopkar, Basic concept of Analytical Chemistry, 3rd ed., Age International
Publisher 2008.
9. T. Sekine and Y. Hasegawa, Solvent Extraction chemistry, Marcel Dekker, 1977.
10. P. G. Swell and B. Clarke, Chromatographic Separations, Analytical Chemistry by open
learning, John Wiley & Sons, New York, 1987.
11. S. Sindsay, High Performance Liquid Chromatography, Analytical Chemistry by open
learning, John Wiley & Sons, New York, 1987.
12. A. J. Bard and L. R. Faulkner, Electrochemical Methods, Wiley, New York, 1980
13. A. M. Bond, Modern Polarographic Methods in Analytical Chemistry, Marcel Dekker,
New York, 1980.
14. L. C. Thomas and G. J. Chamberline, Colorimetric Analytical Methods, 9th ed., The
Fintometer Ltd., Salisbury, England, 1980.
15. T. C. Morrili, R. m. Silverstein and G. C. Bassler, Spectrometric Identification of Organic
Compounds, Wiley, 1981.
16. Vogel‟s Text Book of Quantitative Organic Analysis, 2th ed. ELBS.
17. R. A. Day, Jr. and A. L. Underwood, Quantitative Analysis, 6th ed., Prentice Hall of India
Pvt. Ltd., New Delhi, 1993.
18. Jared L. Anderson, Alain Berthod, Veronica Pino, and Apryll M. Stalcup (ed),Analytical
Separation Science (Volume 1-5). WILEY-VCH 2015.
19. Jack Cazes (ed) Ewing’s Analytical Instrumentation Handbook, 3rd edition, Marcel
Dekker 2009.
20. R. Kellner, J.M. Mermet, M. Oto, M. Valcarcel, H. M. Widmer (ed), Analytical
Chemistry: A modern Approach to Analytical Science 2nd edition. WILEY-VCH 2004.
21. Solid phase Extraction- Principles, Techniques and Applications, N. J. K.
Simpson, Marcel Dekker, New York, (2000).
26
CHEM 105: PHYSICAL CHEMISTRY PRACTICAL-I
Instrumental Experiments:
Conductometryand Potentiometry
1. Titration of a mixture of trichloroacetic acid, monochloroacetic acid and acetic acid with
sodium hydroxide conductometrically.
2. Verification of Ostwald‟s dilution law and determination of the dissociation constant of a weak
monobasic acid conductometrically.
3. Study of the effect of substituent on dissociation constant of acetic acid conductometrically.
4. Determination of concentrations and amounts of iodide, bromide and chloride in the mixture by
potentiometric titration with silver nitrate.
5. Determination of solubility product of silver chloride potentiometrically using a concentration
cell.
6. Determination of the formula of the silver-ammonia complex by potentiometric method.
7. Determination of pK values of phosphoric acid by potentiometric titration with sodium
hydroxide using a glass electrode.
8. Determination of acidic and basic dissociation constants of an amino acid and hence the iso-
electric point of the acid.
CHEM-106: INORGANIC CHEMISTRY PRACTICAL-I
Synthesis, Purification and Analysis of the following Inorganic Preparations:

1. Potassium trioxalatochromate (III)
2. Bis(enthylenediammine) copper (II) sulphate
3. Hexammine nickel (II) chloride/sulphate
4. Potassium dioxalato cuprate(II) dihydrate
5. Potassium trioxalatoaluminate(III) hydrate
Reference books:
1. A. I. Vogel, Vogel‟s Text Book of Quantitative Inorganic Analysis, 6th Ed., Pearson
Education, 2000.
2. J. D. Woolins, Inorganic Experiments, Wiley-VCH Verlag GmbH and Co., 2003.
3. W. G. Palmer, Experiments in Inorganic Chemistry, Cambridge University Press,
1954.
4. G. Raj, Advanced Practical Inorganic Chemistry,
5. G. Brauer, Handbook of Preparative Inorganic Chemistry, Vol. 1 and 2, Academic
Press, 1967.
6. G. Marr and B. W. Rockette, Practical Inorganic Chemistry, Van Nostrnad Reinhond,
1972.
7. G. Pass and H. Sutcliffe, Practical Inorganic Chemistry, 2nd Ed., Chapman and Hall,
1985.
27
CHEM 107: ORGANIC CHEMISTRY PRACTICAL-I
One step preparations (0.5 to 1.0 g scale):
The candidate is expected to perform any 10 of the following preaparations and submit the
crystallized preparation and TLC analysis of the purified product, mp, % yields, etc.
1.Bromobenzene to p-nitro bromobenzene
2.Nitrobenzene to m-dinitrobromobenzene
3.Benzoin to Benzil
4.Anthracene to Anthraquinone
5.o-phenylenediamine to 2-methyl benzimidazole
6.o-phenylenediamine to 2,3-diphenylquinoxaline
7.Anthracene-Maleic Anhydride adduct
8.p-bromoacetanilide to p-bromoaniline
9.5,5-diphenylhydantoin from urea and benzil
10. p-benzoquinone to 1,2,4-triacetoxybenzene
11. 2-naphthol to BINOL
12. o-phenylenediamine to benzotriazole
Reference Books:
1.Elementary Practical Organic chemistry Part-I small scale preparations, A.L. Vogel
(Longman)
2.Laboratory Manual of organic chemistry, B.B. Dey and M.V. Sitaram revised by T.R
Govindachari (Allied Publishers Ltd. )
CHEM 108: ANALYTICAL CHEMISTRY PRACTICAL-I

Non-Instrumental Experiments:
1. Calibration of a 10 mL pipette by weighing at room temperature and reporting the result
with statistical data.
2. Determination of Manganese from pyrolusite by potassium permanganate method.
3. Estimation of vitamin C by titration with potassium bromate.
4. Determination of number of nitro group in organic compound by titanium method.
5. Separation and determination of Fe (III) and Mg (II) /Zn (II) using ethyl acetate /ether as a
solvent.
6. Separation of Zn (II) and Mg (II) in a mixture using anion exchanger.
28
SEMESTER-II
No. of Examination
No. of hours per Mid End- Total
Course
Title of the Course Credits SEMESTE Sem Sem Marks
Code -R Marks Marks
CHEM
Physical Chemistry II 4 60 40 60 100
201
CHEM
Inorganic Chemistry II 4 60 40 60 100
202
CHEM
Organic Chemistry II 4 60 40 60 100
203
CHEM
Analytical Chemistry II 4 60 40 60 100
204
2 - - 50 50
205 Practical II
CHEM Inorganic Chemistry
2 - - 50 50
206 Practical II
CHEM Organic Chemistry
2 - - 50 50
207 Practical II
CHEM Analytical Chemistry
2 - - 50 50
208 Practical II
Total 24 Total 600
*Practical component involves 16 h per week laboratory work for 15 weeks.
29
SYLLABUS: SEMESTER-II
CHEM 201: PHYSICAL CHEMISTRY-II

Unit-I THERMODYNAMICS-II [15 L]
Partial molar quantities, chemical potential for ideal gas, gas mixtures, Gibbs free energy of
mixing, entropy and volume of mixing, Gibbs Duhem equation, Variation of chemical
potential with pressure and temperature.
Excess functions (Chemical potential, Gibbs free energy and enthalpy function), Equilibrium
constant and its dependence on temperature and pressure.
Unit-II APPLIED ASPECTS OF QUANTUM CHEMISTRY [15L]

Application of Quantum Chemistry in Vibrational motion:
The one-dimensional harmonic oscillator: Classical and Quantum mechanical treatment,
Hermite polynomials, Wavefunctions, probability densities, and energy levels
Application of Quantum Chemistry in Rotational motion:
Spherical polar coordinates, Separation of variables, The rigid rotor: Legendre functions,
energy levels and wave functions.
Application of Quantum Chemistry in Atomic system:
The hydrogen atom and hydrogen-like ions, Reduction of the two-particle problem to two
one-particle problems, Solutions to R(r), Θ(θ) and Φ(ϕ) equations, Hydrogen-like orbitals,
sketches of wave functions (ψ) and probability densities (  ), polar plots of angular parts,
2
orbital and spin angular momentum, spin orbitals.
Unit-III APPLICATIONS OF THERMODYNAMICS AND ELECTROCHEMISTRY

[15L]
Experimental techniques for determination of thermodynamic quantities: Bomb Calorimeter,
Coffee Cup Calorimeter, Differential Scanning Calorimeter.
Exergonic and endergonic reactions, Thermodynamics of ATP, applications of
thermodynamics to ultra-purity and controlled purity (Zone Refining and zone levelling).
Debye-Hückel theory of strong electrolyte, ionic atmosphere, activity coefficients of
electrolyte solutions- Debye-Hückel limiting law, extension to higher concentrations.
Electrolytic conductance and ion-ion interactions, Debye-Hückel-Onsager equation, validity
of equation, Debye-Falkenhagen effect, Wien effect, weak electrolyte and Debye-Huckel
theory.
Determination of thermodynamic functions of cell reaction.
Electrochemistry in water and effluent treatment.
Unit-IV MOLECULAR REACTION DYNAMICS [15L]

Collision theory, steric factor, activated complex theory, reaction coordinate and transition
state, thermodynamic aspects, reaction between ions, salt effects, dynamics of molecular
collisions.
Homogeneous catalysis – enzyme catalysis, Michaelis-Menten mechanism, acid base
catalysis.
Heterogeneous catalysis – Examples: hydrogenation, oxidation, cracking and forming.

Derivation not expected
30
Note: Numerical and theoretical problems from each Unit- are expected.
Reference books:
1. Peter Atkins and Julio de Paula, Atkin’s Physical Chemistry, 7th ed., Oxford
2. K. J. Laidler and J. H. Meiser, Physical Chemistry, 2nd ed., CBS Publishers and
Distributors, New Delhi, 1999.
3. Robert J. Silby and Robert A. Alberty, Physical Chemistry, 3rd ed., John Wiley and
Sons (Asia) Pte. Ltd., 2002.
4. Ira R. Levine, Physical Chemistry, 5th ed., Tata McGraw-Hill, New Delhi, 2002.
5. G. W. Castellan, Physical Chemistry, 3rd ed., Narosa Publishing House, New Delhi,
1983.
7. S. Glasstone, Text Book of Physical Chemistry, 2nd ed., McMillan and Co. Ltd.,
London, 1962.
8. Derek Pletcher, Industrial Electrochemistry, London New York.
9. S. Glasstone, Thermodynamics for Chemists, Affiliated East-West Press, New Delhi,
1964.
10. Ira N. Levine, Quantum Chemistry, 5th ed., Pearson Education (Singapore) Pte. Ltd.,
11. J. P. Lowe, Quantum Chemistry, 2nd ed., Academic Press, New York, 1993.
12. R. Anantharaman, Fundamentals of Quantum Chemistry, McMillan India Limited,
2001.
14. R. K. Prasad, Quantum Chemistry, 2nd ed., New Age International Publishers, 2000.
15. D. O. Hayward, Quantum Mechanics for Chemists, Royal Society for Chemists, 2002.
16. Samuel Glasstone,An introduction to electrochemistry,East West edition, New Delhi.
17. G. L. Agarwal, Basics Chemical kinetics, Tata Mcgraw Hill, New Delhi.
18. D. R. Crow, Principles and Applications of Electrochemistry, 4th edition, Blackie,
London, 1994.
19. J.O‟m. Bockris and A. K. N. Reddy, Modern Electrochemistry-Vol. 1 and 2, Plenum
press, New York.
20. R. A. Robinson and R.H. Stokes, Electrolyte Solutions, 2nd Edition, Butterworths,
London 1959.
21. R. P. Rastogi, R. R. Mishra, An Introduction to Chemical Thermodynamics, Vikas
Publishing House Pvt. Ltd.
22. K. J. Laidler, Chemical Kinetics, 3rd ed., Pearson Education.

1. W. G. Davis, Introduction to Chemical Thermodynamics – A Non-Calculus Approach,
Saunders, Philadelphia, 1972.
2. I. M. Klotz and R. M. Rosenberg, Chemical Thermodynamics, 5th ed., John Wiley and
Sons, Inc., 1994.
3. Peter A. Rock, Chemical Thermodynamics, University Science Books, Oxford
31
CHEM-202: INORGANIC CHEMISTRY-II
Unit-I SOLID STATE CHEMISTRY AND NANOMATERIALS [15L]
(A) Solid State Chemistry
(i) Recapitulation of basic solid state chemistry.
(ii) Structures of compounds of the type: AB [zinc sulfide (ZnS), nickel arsenide
(NiAs)], AB2 [fluorite (CaF2), antifluorite (Na2O), rutile (TiO2) and layer
structures viz., cadmium chloride (CdCl2) and cadmium iodide, (CdI2)].
(iii) Principles, merits and demerits with suitable examples of: ceramic method,
precursor method, sol-gel method, microwave synthesis for the preparation
of inorganic solids.
(B) Nanomaterials
(i) Introduction to nanomaterials.
(ii)Preparative methods: Chemical methods, Biological methods; Role of
capping agents.
(iii)Applications of nanomaterials in electronics and biomedical field.
Unit-II MOLECULAR SYMMETRY AND GROUP THEORY [15L]
(i)Symmetry elements and symmetry operations, product of symmetry
operations, Cartesian coordinate system and symmetry elements.
(ii)Symmetry classification of molecules: point groups, mathematical
requirement for a point group, systematic assignment of point groups to
molecules.
(iii) Identification of molecular point groups of molecules having low symmetry,
high symmetry and special symmetry.
(iv) Descent in symmetry of molecules with substitution.
(v)Group multiplication tables, classes of symmetry operations.
(vi) Symmetry criteria for optical activity, Symmetry restrictions on dipole
moment.
Unit-III ENVIRONMENTAL CHEMISTRY [15L]
(i) Chemical Toxicology:
toxic chemicals in the environment, biochemical effects and speciation of
toxic elements like arsenic, lead, mercury and cadmium; antidotes for the
toxic elements. Biochemical effects of fluoride and pesticides.
(ii)Radiation pollution:
Sources and biological implication of radioactive pollutants.
(iii)Solar energy:
Use of solar energy in space heating and water heating; Production of
electricity using solar trough collectors, Power tower and solar pond; solar
energy for driving vehicles.
(iv)Power from other sources:
Hydro power, Wind power, Geothermal energy, Ocean thermal energy
conversion (OTEC), Tidal power.
Unit-IV BIOINORGANIC CHEMISTRY [15L]]
(i) Biological oxygen carriers:
Myoglobin, hemoglobin, hemerythrene and hemocyanine. Biochemical effect
of cyanide, Hill equation, Bohr effect and their implications.
(ii)Reactions of dioxygen in biological system with examples of peroxidase,
monooxygenase, superoxide dismutase and oxidase reactions.
(iii)Nitrogen fixation: Nitrogenase, Hydrogenases.
(iv)Metal ion transport and storage: Ionophores, transferrin and Ferritin.
(v)Metal ions in medicines: cis-platin and related compounds.
32
Reference books:
Unit-I
1. A. R. West, Solid State Chemistry and Its Applications, John Wiley & Sons, 1987.
2. L. V. Azaroff, Introduction to solids, Tata McGraw Hill Book Co, 1977.
3. H. V. Keer, Principles of Solid State, Wiley Eastern Ltd., 1993.
4. C. N. R. Rao and G. Gopalkrishnan, New Directions in solid state chemistry, 2 nd Ed.,
Cambridge University Press, 1997.
5. Lesley E. Smart and Elaine A. Moore, Solid State Chemistry – An introduction, 3rd Ed.,
Taylor and Francis, 2005.
6. B. R. Puri, L. R. Sharma and K. C. Kalia, Principles of Inorganic Chemistry, Milestone,
2014.
7. S. K. Kulkarni, Nanotechnology-Principles and Practices, Capital Publishing Co., 2007.
8. G. Cao, Nanostructures and Nanomaterials- Synthesis, Properties and Applications,
Imperial college Press, 2004.
9. C. N. R. Rao, A. Muller and A. K. Cheetham, The Chemistry of Nanomaterials-
Synthesis, Properties and Applications, Volume-I, Wiley VCH, 2004.
Unit-II
1. K.V.Reddy, Symmetry and Spectroscopy of Molecules, 2nd Ed., New Age International
Publishers2009.
2. R. L. Carter, Molecular Symmetry and Group Theory, John Wiley & Sons, 1998.
3. A.S. Kunju and G. Krishnan, Group Theory and its Applications in Chemistry, PHI-
Learning, 2010.
4. F. A. Cotton, Chemical Applications of Group Theory, 2nd Ed., Wiley Eastern Ltd.,
1989.
5. G. Raj, A. Bhagi and V. Jain, Group Theory and Symmetry in Chemistry, 3rd Ed.,
Krishna Prakashan, 2010.
6. P. Atkins, T. Overton, J. Rourke, M. Weller and F. Armstrong, Inorganic Chemistry, 5 th
Ed., Oxford University Press, 2010.
7. R. S. Drago, Physical Methods in Inorganic Chemistry, Affiliated East-West Press Pvt.
Ltd., 2014.
Unit-III
1. A. K. De, Environmental Chemistry, 7th Ed., New Age International Publishers, 2007.
2. G. S. Sodhi, Fundamental Concepts of Environmental Chemistry, 3rd Ed., Narosa
Publishing House, 2013.
3. S. S. Dara and D. D. Mishra, A Textbook of Enviromental Chemistry and Pollution
Control, S. Chand & Company Ltd., 2012.
4. D. Banerjea, Coordination Chemistry, Tata Mc Graw Hill, 1993.
5. S. K. Banerji, Environmental Chemistry, 2nd Ed., Prentice-Hall of India, 2005.
6. R. A. Bailey, H. M. Clark, J. P. Ferris, S. Krause and R. L. Strong, Chemistry of
Environment, 2nd Ed., Academic Press, 2005.
7. J. E. Girard, Principles of Environmental Chemistry, 2nd Ed., Jones and Bartlett
publishers, 2011.
33
8. H. Kaur, Environmental Chemistry, Pragati Prakashan, 8th Ed., 2014.
Unit-IV
1. I. Bertini, H.B.Gray, S. J. Lippard and J.S. Valentine, Bioinorganic Chemistry, 1 st
Indian Ed., Viva Books, 1998.
2. D. Banerjea, Coordination Chemistry, Tata Mc Graw Hill, 1993.
3. R. W. Hay, Bioinorganic Chemistry, Ellis Harwood, 1984.
4. J. A. Cowan, Inorganic Biochemistry-An introduction, VCH Publication, 1993.
5. S. J. Lippard and J. M. Berg, Principles of Bioinorganic Chemistry, University Science
Publications, Mill Valley, Caligronic, 1994.
6. G. N. Mukherjee and A. Das, Elements of Bioinorganic Chemistry, Dhuri & Sons,
1988.
CHEM 203: ORGANIC CHEMISTRY-II

Unit-IPHYSICAL ORGANIC CHEMISTRY AND AROMATICITY [15L]
1.1Transition state theory, Arrhenius equation and its application to estimate Eact,
Hammond‟s postulate, Principle of microscopic reversibility, Kinetics v\s
Thermodynamic control.
1.2Influence of solvent polarity, solvent scales (Y-scale), solvatochromism, (Z and ET
Scales), ionic strengths and salt effect, Acid-base catalysis, Bronsted catalysis equation.
1.3Structural, thermochemical and magnetic criteria for aromaticity, including NMR
characteristics of aromatic systems, DRE and REPE, London Diamagnetism,
Diamagnetic exaltation and concept of closed configuration.
1.4Application of HMO theory to monocyclic conjugated systems, Frost-Muslin diagrams,
Huckel‟s (4n+2) π electron rule, Exceptions to (4n+2) π electron rule and 4n rules.
1.5Aromatic, Antiaromatic and Homoaromatic compounds upto 18 carbon atoms.
Aromaticity of benzenoid systems, heterocycles, metallocenes, azulenes,
annulenesconjugated molecules with exocyclic double bonds and tropylium cations.
Unit-IIELIMINATION AND NUCLEOPHILIC SUBSTITUTION REACTIONS
[15 L]
2.1 Types of elimination reactions, E1and E2mechanisms.
2.2 Orientation of elimination reactions: Saytzeff and Hoffmann rules. E2reactions of vinyl
halide, E1cB mechanism.
2.3Pyrrolytic elimination: Chugaev reaction, Cope reaction, Hoffmann‟s and Pyrrolysis of
acetates.
2.4 Aliphatic nucleophilic substitution at sp3 carbon: SN1, SN2, SNi, SNcA reactions. Ion pair in
SN1, reactions, Stereochemistry of all the above reactions, Factors affecting these
reactions: substrate nucleophilicity, solvent, steric effect, hard-soft interaction, leaving
group.
2.5Nucleophilic substitution reactions at sp2 (vinylic) carbon.
2.6Aromatic nucleophilic substitution reaction: SNAr, SN1,Benzynemechanism, ipso, cine and
tele substitutions, vicarious substitution.
34
Unit-III OXIDATION-REDUCTION [15 L]
3.1Preparation of reagents (wherever applicable), mechanism and applications of the
following:
Epoxidation, Baeyer-Villiger Oxidation and Oppenauer Oxidation.Oxidations using
Osmium Tetroxide, Lead Tetraacetate, Periodic acid, Selenium dioxide, PCC and PDC.
3.2Dehydrogenation with DDQ and TCQ, and Ozonolysis
3.3Preparation of reagents (wherever applicable), mechanism and applications of the
following:
Wolf-Kishner reduction, Clemmensen reduction, Meerwein-Pondorff-Verley reduction,
Birch reduction, Reductions with NaBH4, LiAlH4and DIBAL.
3.4Homogeneous reductions: Wilkinson‟s catalysts and related systems.
Unit-IVREACTIONS AND REARRANGEMENTS [15 L]
4.1 Mechanism, stereochemistry (if applicable) and applications of the following:
Arndt-Eistert reaction, Baylis-Hilman reaction, McMurry Coupling, Mitsunobu reaction
and Mukiyama esterification, Woodward Prevost Hydroxylation.
4.2 Mechanism, stereochemistry (if applicable) and applications of the following:
Cope rearrangement, Claisen rearrangement, Dienone-Phenol rearrangement, Favroskii
rearrangement, Fries rearrangement and Tiffeneau-Demjanov rearrangement.
4.3Ester hydrolysis (all 8 mechanisms of acid and base catalyzed hydrolysis)
Reference books:
1.Organic Chemistry, J. Claydens, N. Greeves, S. Warren and P. Wothers, Oxford
University Press.
2.Advanced Organic Chemistry, F.A. Carey and R.J. Sundberg, Part A, page no. 713-769,
and B, Plenum Press.
3.Stereochemistry: Conformation and mechamism, P.S. Kalsi, New Age International, New
Delhi.
4.Stereochemistry of carbon compounds, E.L Eliel, S.H Wilen and L.N Manden, Wiley.
5.Stereochemistry of Organic Compounds- Principles and Applications, D. Nasipuri. New
International Publishers Ltd.
6.March‟s Advanced Organic Chemistry: Reactions, Mechanisms and Structure, Michael
B. Smith, Jerry March, Wiley.
7.Advanced Organic Chemistry: Reactions and mechanism, B. Miller and R. Prasad,
Pearson Education.
8.Advanced Organic Chemistry: Reaction mechanisms, R. Bruckner, Academic Press.
9.Understanding Organic Reaction Mechanisms, Adams Jacobs, Cambridge University
Press.
10. Writing Reaction Mechanism in organic chemistry, A. Miller, P.H. Solomons,
Academic Press.
11. Principles of Organic Synthesis, R.O.C. Norman and J.M Coxon, Nelson Thornes.
35
12. Advanced Organic Chemistry: Reactions and mechanism, L.G. Wade, Jr., Maya
Shankar Singh, Pearson Education.
13. Mechanism in Organic Chemistry, Peter sykes, 6th edition onwards.
14. Physical Organic Chemistry, Neil Isaacs
15. Modern Physical Organic Chemistry, Eric V. Anslyn and Dennis A. Dougherty
16. Comprehensive Organic chemistry, Barton and Ollis, Vol 1, Page No. 215-240.
CHEM 204: ANALYTICAL CHEMISTRY-II

Unit-IELECTROANALYTICAL CHEMISTRY[15L]
1.1Ion selective potentiometry: Basic concept, solid state, precipitate and liquid-liquid
membrane, enzyme and gas sensing electrodes with applications.[8L]
1.2Introduction to modern voltammetric techniques viz., Differential pulse polarography,
Cyclic voltammetry and Stripping (cathodic & anodic) voltammetry.[7L]
Unit-IISPECTROSCOPIC METHODS [15L]
2.1Magnetic resonance spectroscopy:
Basic principles, instrumentation and sample handling, Quantitative applications of
proton NMR, Introduction to Carbon–13, Phosphorous-31 and Fluorine-19 with
applications. [8L]
2.2Mass spectrometry:
Recapitulation, instrumentation; ion sources for molecular studies; electron impact,
chemical ionization field ionization, field desorption, fast atom bombardment and
MALDI sources. Mass analyzers: quadrupole, time of flight and ion trap,
Applications.[7L]
Unit-IIIMISCELLANEOUS TECHNIQUES[15L]
3.1 X-ray spectroscopy:
Principles, instrument components and applications of X-ray fluorescence, absorption and
diffraction methods.[8L]
3.2 Introduction to surface analytical techniques.[3L]
3.3 Electron Spectroscopy for Chemical Analysis: Principle, Instrumentation and
applications.[4L]
Unit-IVAUTOMATION IN CHEMICAL ANALYSIS AND ELECTROPHORESIS
[15L]
4.1 An overview of automated instruments and instrumentation, process control analysis;
Types of automatic analytical systems: Flow injection analysis, automatic organic
elemental analyzers, Gas monitoring equipment. [8L]
4.2 Electrophoretic methods [7L]
Reference books:
1. D. A. Skoog, F. J. Holler, and T. A. Nieman, Principles of Instrumental Analysis, 5th
ed., Philadelphia: Saunders College Publishing, 1998.
2. D. A. Skoog, D. M. West, F. J. Holler and S. R. Crouch, Fundamentals of
Analytical Chemistry, 8th ed., Philadelphia: Saunders College Publishing, 2004.
3. G. D. Christian, Analytical Chemistry, 6th ed., John Wiley and Sons, New York,
2003.
36
4. G. H. Jeffery, J. Bassett, J. Mendham and R. C. Denney, Vogel’s Textbook of
Quantitative Chemical Analysis, 6th ed., ELBS, Longman Scientific & Technical,
England, 2002.
5. H. H. Willard, L. L. Merrit, jr., J. A. Dean and F. A. Settle, Jr., Instrumental
Methods of Analysis, 6th ed., CBS 1986.
6. R. D. Braun, Introduction to Instrumental Analysis, McGraw Hill, 1987.
7. G. H. Morrison and H. Freiser, Solvent Extraction in Analytical Chemistry, John
Wiley & Sons, New York, 1966.
8. S. M. Khopkar, Basic concept of Analytical Chemistry, 3rd ed., Age International
Publisher 2008.
9. T. Sekine and Y. Hasegawa, Solvent Extraction chemistry, Marcel Dekker, 1977.
10.P. G. Swell and B. Clarke, Chromatographic Separations, Analytical Chemistry by
open learning, John Wiley & Sons, New York, 1987.
11.S. Sindsay, High Performance Liquid Chromatography, Analytical Chemistry by
open learning, John Wiley & Sons, New York, 1987.
12.A. J. Bard and L. R. Faulkner, Electrochemical Methods, Wiley, New York, 1980
13.A. M. Bond, Modern Polarographic Methods in Analytical Chemistry, Marcel
Dekker, New York, 1980.
14.L. C. Thomas and G. J. Chamberline, Colorimetric Analytical Methods, 9th ed.,
The Fintometer Ltd., Salisbury, England, 1980.
15.T. C. Morrili, R. m. Silverstein and G. C. Bassler, Spectrometric Identification of
Organic Compounds, Wiley, 1981.
16.Vogel‟s Text Book of Quantitative Organic Analysis, 2th ed. ELBS.
17.R. A. Day, Jr. and A. L. Underwood, Quantitative Analysis, 6th ed., Prentice Hall
of India Pvt. Ltd., New Delhi, 1993.
18. Jared L. Anderson, Alain Berthod, Veronica Pino, and Apryll M. Stalcup
(ed),Analytical Separation Science (Volume 1-5). WILEY-VCH 2015.
19.Jack Cazes (ed) Ewing’s Analytical Instrumentation Handbook, 3rd edition, Marcel
Dekker 2009.
20. R. Kellner, J.M. Mermet, M. Oto, M. Valcarcel, H. M. Widmer (ed), Analytical
Chemistry: A modern Approach to Analytical Science 2nd edition. WILEY-VCH
2004.
CHEM 205: PHYSICAL CHEMISTRY PRACTICAL-II

Non-Instrumental Experiments:
Thermodynamics, Phase Rule and Reaction Kinetics:
1. Determination of heat of solution of benzoic acid by solubility measurements.
2. Determination of heat of solution of salicylic acid by solubility measurements.
3. Study of three-component system: Water-Acetic acid-Chloroform.
4. Study of three-component system: Water–Toluene-Acetic acid.
5. Study of variation of solubility of calcium sulphate with ionic strength and hence determine
the thermodynamic solubility product. (Complexometric titration with EDTA)
6. Determination of equilibrium constant of the reaction KI + I2 KI3 by distribution method.
7. Investigation of the reaction between acetone and iodine.
37
CHEM-206: INORGANIC CHEMISTRY PRACTICAL-II
Analysis of Complex Materials:
1. Devarda‟s Alloy: Cu by EDTA method, Al by Gravimetry using oxine
2. Cu-Ni Alloy: Cu by iodometric method; Ni gravimetrically by DMG method.
3. Solder Alloy: Sn gravimetrically by oxide method; Pb by EDTA method.
4. Lime Stone Ore: Loss on ignition; Ca by EDTA method.
5. Haematite Ore: Acid insoluble residue; Fe by redox titration.
Reference books:
1. A. I. Vogel, Vogel‟s Text Book of Quantitative Inorganic Analysis, 6th Ed., Pearson
Education, 2000.
2. J. D. Woolins, Inorganic Experiments, Wiley-VCH Verlag GmbH and Co., 2003.
3. W. G. Palmer, Experiments in Inorganic Chemistry, Cambridge University Press,
1954.
4. G. Raj, Advanced Practical Inorganic Chemistry,
5. G. Brauer, Handbook of Preparative Inorganic Chemistry, Vol. 1 and 2, Academic
Press, 1967.
6. G. Marr and B. W. Rockette, Practical Inorganic Chemistry, Van Nostrnad Reinhond,
1972.
7. G. Pass and H. Sutcliffe, Practical Inorganic Chemistry, 2nd Ed., Chapman and Hall,
1985.
CHEM 207: ORGANIC CHEMISTRY PRACTICAL-II

Separation of Binary mixture by microanalytical technique
Separation of binary mixture using physical and chemical methods. Identification of one
of the compounds and checking its purity by TLC. Preparation of the derivative of one of
the compounds. The following types are expected: (i) Solid-Solid (ii) Non-volatile liquid-
Non-volatile liquid (iii) Water-soluble/insoluble solid-Non-volatile liquid with
compounds from the same or different chemical classes in all three categories.
The candidate is expected to carry out separation of 10 mixtures.
Reference Books:
1.Systematic Qualitative organic analysis, H. Middleton (Orient Longman)
2.A Handbook of Organic Analysis, H.T. Clark (Orient Longman)
3.Systematic Identification of organic compounds, R.L. Shriner (John Wiley, New York)
38
CHEM 208: ANALYTICAL CHEMISTRY PRACTICAL-II
Instrumental Experiments:
1. Non aqueous titration: Determination of sodium benzoate / glycine by using
perchloric acid in glacial acetic acid by potentiometry using glass-calomel system.
2.Determination of glucose by Folin-Wu method.
3.Determination of nitrite in a water sample by colorimetric method.
4.Determination of chromium and manganese by simultaneous spectrophotometry.
5.Determination of silica by Molybdenum Blue method.
6.Flame Photometric determination of Li /Na/K by standard addition method.
39
SEMESTER-III: PHYSICAL CHEMISTRY
Examination
No. of hours
Course No. of Continuous End- Total
Title of the Course per
Code Credits Evaluation Sem Marks
SEMESTER
Marks Marks
CHEM Solid State
4 60 40 60 100
311 Chemistry
CHEM
Spectroscopy 4 60 40 60 100
312
Statistical
thermodynamics,
CHEM thermodynamics of
4 60 40 60 100
313 biological systems
&
electrochemistry-I
CHEM
Interfacial Science 4 60 40 60 100
314 EC-I
CHEM Some Selected
315 EC- Topics in Physical 4 60 40 60 100
II Chemistry
4 - - 100 100
316 Practical III
4 - - 100 100
317 Practical IV
No. of CREDITS: 24 TOTAL MARKS: 600

Students will have to select one of the electives i.e. CHEM 314 or CHEM 315
Practical component involves 16 hr per week of laboratory work for 15 weeks.
40
SEMESTER-III: PHYSICAL CHEMISTRY
CHEM 311: SOLID STATE CHEMISTRY

Unit-I: BONDING, STRUCTURE AND PREPARATIVE METHODS [15L]
Bonding and Structure: Classification of solids based on nature of
forces (Ionic, Covalent, Metallic, van der Waals, Hydrogen-bonded),
Crystal Structures: Symmetry and Choice of Unit- cell, Bravais lattice,
Miller indices, Point groups and space groups, Close packing, Lattices
and Unit- cells, Crystalline solids, ionic radii, radius ratio rule, lattice
energy, crystal structure determination by powder diffraction and
single crystal X-ray diffraction.
Preparative Methods: Solid state reactions (General Principles,
precursor methods), Crystallization of solutions, melts, glasses and
gels, vapour phase transport methods, Preparation of thin films, growth
of single crystals, high pressure and hydrothermal methods.
Some important solid-state materials: Magnetoresisters, Zeolites,
Intercalation compounds, fullerides.
Unit-II: DEFECTS AND DIFFUSION IN SOLIDS [15L]
Defects and non-stoichiometry: Types of Defects: Point defects,
plane defects, line defects. Thermodynamics of defects, Solid solutions.
Diffusion in solids: Mechanisms, Steady state and non-steady state
diffusion, factors affecting diffusion, Kirkendall effect.
Unit-III: ELECTRICAL AND MAGNETICPROPERTIES [15L]
Electrical Properties:
Electrical conductivity of metals, Free electron theory, semiconductors,
Intrinsic and extrinsic semiconductivity, Band theory,
Superconductivity: Conventional Superconductors, Bardeen-Cooper-
Schrieffer (BCS) theory, High temperature Superconductors,
Ferromagnetic Superconductors, Uses of High temperature
Superconductors.
Magnetic Properties:
Diamagnetism, paramagnetism, ferromagnetism, antiferromagnetism,
ferrimagnetism. Calculation of magnetic moments, influence of
temperature on magnetic behaviour, domains and hysteresis, Soft and
hard magnetic materials.
Unit-IV: OPTICAL PROPERTIES, DIELECTRIC PROPERTIES AND [15L]
PHASE TRANSFORMATIONS IN SOLIDS
Optical Properties:
Electron emission in Metals, Photovoltaic effect, Luminescence, Laser
and Maser actions, The Ruby laser, Light emitting diodes, Optical
41
fibers.
Dielectric Properties:
Dielectric constant, Clausius-Mosotti equation, Piezoelectricity,
Ferroelectricity, Antiferroelectricity, Ferrielectricity.
Phase transformations in solids:
Buerger‟s classification, Thermodynamic classification, Kinetics of
phase transitions, temperature and pressure induced transformations,
Martensitic transformations, Order-disorder transitions.
* Numericals/Problems are expected from each Unit-
Reference books:
1. H. V. Keer, Principles of the Solid State, New Age International Publishers,
2. A. R. West, Solid State Chemistry and its Applications, John Wiley and Sons (Asia) Pte.
Ltd.,
3. L. E. Smart and E. A. Moore, Solid State Chemistry – An Introduction, 3rd Ed., Taylor
and Francis, 2005.
4. V. Raghavan, Materials Science and Engineering, Fifth Ed., Prentice-Hall of India Pvt.
Ltd., New Delhi, 2004.
5. William D. Callister, Jr., Materials Science and Engineering, An Introduction, Fifth Ed.,
John Wiley and Sons (Asia) Pte. Ltd., 2001.
6. S. O. Pillai, Solid State Physics, Fifth Ed., New Age International Publishers, 2002.
7. Leonid V. Azaroff, Introduction to Solids, Tata-McGraw-Hill Publishing Co. Ltd., New
Delhi, 1977.
8. Sandra E. Dann, Reactions and Characterization of Solids, Royal Society of Chemistry,
2000.
CHEM 312: SPECTROSCOPY

Unit-I BASIC PRINCIPLES OF SPECTROSCOPY [15L]
Absorption and Emission of Radiation, Width and intensity of
spectral lines, transition probability and selection rules, Fourier
transform spectroscopy, computer averaging of signals (CAT),
lasers.
Microwave spectroscopy: Rotational spectra of diatomic (non-rigid)
molecules, Population of rotational levels and intensity of rotational
lines, effect of isotopic substitution, rotational spectra of polyatomic
molecules (linear and symmetric top), Stark effect.
Unit-II INFRARED SPECTROSCOPY [15L]
Anharmonic oscillator, Rotational-vibrational spectrum, Breakdown
of Born-Oppenheimer approximation, combinational differences,
vibrations of polyatomic molecules, rotational fine structure of
vibrational spectrum of polyatomic molecules.
Raman spectroscopy:
Classical and quantum theory of Raman scattering, Experimental
Methods, Pure rotational, vibrational and rotational-vibrational
Raman spectrum of diatomic and polyatomic molecules, polarization
42
and depolarization of Raman lines, correlation of infrared and
Raman spectra, normal modes and symmetry, Resonance Raman
Scattering, Surface Enhanced Raman Scattering
Unit-III ELECTRONIC SPECTROSCOPY: [15L]
Vibrational course structure, Progressions and sequences, The
Franck-Condon principle, Deslandres tables, Dissociation energies,
Birge-Sponer extrapolation, Rotational fine structure, Fortrat
diagram, Predissociation, Electronic spectra of polyatomic
molecules.
Nuclear magnetic resonance spectroscopy: Chemical shift, spin-spin
coupling, Chemical and magnetic equivalence, first and second order
spectra, pulsed NMR, relaxation times, multipulse techniques, spin
echoes, two- and three- dimensional NMR, NMR of nuclei other
than proton, nuclear overhauser effect.
Unit- IV NUCLEAR QUADRUPLE RESONANCE: [15L]
Principle, Transitions for axially and non-axially symmetric systems,
applications.
Electron spin resonance spectroscopy:
Basic theory, Instrumental Aspects, The g  factor, hyperfine
structure, applications to free radicals, inorganic radicals, transition
metal complexes.
Mössbauer Spectroscopy:
Principles, Recoilless emission and absorption of γ-rays,
experimental methods, isomer shift, hyperfine structure (quadrupole
interaction), magnetic hyperfine interaction, applications.
Reference books:
1. C. N. Banwell and E. M. McCash, Fundamentals of Molecular Spectroscopy, 4th Ed.,
Tata-McGraw-Hill, 1994.
2. M. L. Gupta, Atomic and Molecular Spectroscopy, New Age International Publishers,
2001.
3. H. S. Randhawa, Modern Molecular Spectroscopy, McMillan India Ltd., 2003
4. G. Aruldas, Molecular Structure and Spectroscopy, Prentice-Hall of India, 2001.
5. J. Michael Hollas, Modern Spectroscopy, 4th Ed., John Wiley and Sons, 2004.

1. R. Drago, Physical Methods for Chemists, Saunders, Philadelphia, 1992.
2. B. P. Straughan and S. Walker (Eds.), Spectroscopy – Vol 1-3, Chapman and Hall, New
York, 1976.
3. R. K. Harris, Nuclear Magnetic Resonance Spectroscopy, Pitman, London, 1983.
4. Donald L. Pavia, Gary M. Lampman and George S. Kriz, Introduction to Spectroscopy,
3rd ed., Thomson, Brooks/Cole, 2001.
43
CHEM 313: STATISTICAL THERMODYNAMICS, THERMODYNAMICS OF
BIOLOGICAL SYSTEMS & ELECTROCHEMISTRY-I
Unit-I FUNDAMENTALS OF STATISTICAL THERMODYNAMICS [15L]
Permutations, probability, microstates and configurations, the most
probable distribution, ensembles, distribution laws: Boltzmann
distribution, Bose-Einstein statistics, Fermi-Dirac statistics. Partition
function, evaluation of translational, rotational, vibrational and electronic
partition functions for ideal gases
Unit- II APPLICATIONS OF STATISTICAL THERMODYNAMICS IN [15L]
CHEMICAL SYSTEMS
Calculation of thermodynamic properties (Energy, Heat capacity,
Enthalpy, Entropy, Helmholtz energy, Gibbs energy) in terms of partition
functions for mono, di and polyatomic gases, equilibrium constants,
residual entropies, heat capacities of ideal gases, heat capacities of solids.
Unit-III THERMODYNAMICS OF BIOLOGICAL SYSTEMS [15L]
Thermodynamics of biopolymer solutions, thermodynamics of biochemical
reactions involving adenosine triphosphate (ATP), osmotic pressure,
membrane equilibrium, muscular contraction and energy generation in
mechano-chemical systems.
Structures and functions of cell membrane, ion transport through cell
membrane and irreversible thermodynamic treatment of membrane
transport.
Biological Buffers.
Unit-IV ELECTROCHEMISTRY-I [15L]
Batteries: Working principle, cell reactions and cell performances of Lithium
Batteries (Primary and secondary), Lithium and Lithium ion batteries.
Fuel cells: Classification, H2O2 fuel cell, choice of electrolyte, advantages,
disadvantages.
Electroplating: Electroplating of metals, factors affecting throwing power of an
electroplating bath, mechanism of electro-deposition, typical electroplating
processes and applications of electroplating metal.
Electrochemical corrosion of metals: Classification of corrosion processes,
conditions for the occurrence of corrosion process, kinetic theory of corrosion and
its application to pure metals, methods of corrosion protection, corrosion of
technical metals.
Reference books:
1. D. A. McQuarrie and J. D. Simon, Molecular Thermodynamics, Viva Books Private
Limited, First Indian Ed., 2004.
2. D. A. McQuarrie and J. D. Simon, Physical Chemistry, a Molecular Approach, Viva
Books Private Limited, First South Asian Ed., 1998. Chap.
44
3. E. D. Kaufmann, Advanced Concepts in Physical Chemistry, McGraw-Hill, 1966.
4. Robert P. H. Gasser and W. Graham Richards, An Introduction to Statistical
Thermodynamics, World Scientific Publishing Co. Pte. Ltd., 1995.
5. William Blum and George B. Hogaboom, Principles of Electroplating and
Electroforming, 3rd ed., McGraw-Hill Book Co., 1949.
6. Frederick A. Lowenheim, Modern Electroplating, 3rd ed. John Wiley Sons, Inc., 1974.
7. L. I. Antropov, Theoretical Electrochemistry, Mir Publishers, Moscow, 1972.
8. H. H. Uhlig and R. W. Rewic, Corrosion and Corrosion Control, John Wiley and Sons,
New York, 1985.
9. Mars G. Fortana, Corrosion Engineering, 3rd ed., McGraw-Hill Book Co., 1987.
10. Nester Perez, Electrochemistry and Corrosion Science, Kluwer Academic Publisher,
2004.
11. R. Narayan and B. Vishwanathan, Chemical and Electrochemical Energy Systems,
Universities Press (India) Ltd., 1998.
12. C. R. Cantor and P. R. Schimmel, Biophysical Chemistry: Part I, II and III, W. H.
Freeman and Co., 1980.
13. R. B. Martin, Introduction to Biophysical Chemistry, McGraw-Hill New York, 1964.
14. S. Ramakrishnan, Biophysical Student Mannual, T. R. Publications (Madras), 1994.
15. J. H. Weil, General Biochemistry, New Age International Publishers, New Delhi.
CHEM 316: PHYSICAL CHEMISTRY PRACTICAL-III

Major Experiments
Distribution Methods:
1.To determine the formula of copper ammonia complex.
2.To determine the formula of silver ammonia complex.
Phase Equilibrium:
1.To determine the freezing point curve of two component simple eutectic system.
2.To determine the freezing point curve of two component compound forming system.
Reaction Kinetics:
1. To study the kinetics of hydrolysis of methyl acetate catalyzed by hydrochloric acid at
different temperatures and to determine the thermodynamic parameters.
2. To study the influence of ionic strength on the rate of reaction between potassium
persulphate and potassium iodide in solution.
3. To study the kinetics of reaction between potassium persulphate and potassium iodide in
solution at different temperatures and determine the thermodynamic parameters.
45
CHEM 317: PHYSICAL CHEMISTRY PRACTICAL-IV
Minor Experiments
Solubility:
Study the variation of solubility of calcium hydroxide in the presence of sodium hydroxide
and hence determine the solubility product at room temperature.
Viscosity Measurements:
1. To determine limiting viscosity number of polystyrene.
2. To determine chain linkage in polyvinyl alcohol from viscosity measurements.
3. To determine relative molecular mass of polystyrene from viscosity measurements.
Surface Chemistry:
1. To determine the critical micelle concentration (CMC) of sodium lauryl sulphate/N-cetyl-
N,N,N-trimethyl ammonium bromide (CTAB) from measurements of conductivities at
different concentrations.
2. To determine the critical micelle concentration (CMC) of sodium lauryl sulphate/N-cetyl-
N,N,N-trimethyl ammonium bromide (CTAB) from measurements of surface tensions at
different concentrations.
Potentiometry / pH metry:
1. To determine the stability constant of the silver-ammonia complex.
2. To determine the transport number of silver and nitrate ions in aqueous solution from the
cell potential of the concentration cell with liquid junction potential.
3. To determine the substitution constants in Hammett equation for 3-aminobenzoic acid/4-
aminobenzoic acid and 3-nitrobenzoic acid/4-nitrobenzoic acid.
Spectrophotometry:
1. To determine the ionization constant of methyl red/ bromophenol blue.
Interpretation of spectra/data-I:
1. Interpretation of vibrational-rotational spectra of rigid and non-rigid diatomic molecules
2. Interpretation of electronic spectra of diatomic molecules.
3. Interpretation of electronic spectra of simple polyatomic molecules.
4. Interpretation of ESR spectra.
5. Interpretation of Mössbauer spectra.
6. Analysis of XRD pattern of cubic system
7. Interpretation of DTA, TG, DTG curves.
Interpretation of spectra/data-II:
Spectral analysis: Structure elucidation with a given set of spectra, Determination of the
degree of un-saturation from molecular formula. Systematic interpretation of set of spectra
including some or all of the following: UV-Vis, IR, PMR, CMR, DEPT, Mass. Identification
of the compound based on systematic interpretation of spectral data would be preferred.
List of reference Books for Practicals and Spectral Interpretaion:

1. B. Vishwanathan and P. S. Raghavan, Practical Physical Chemistry, Viva Books
Private Limited, 2005.
46
2. A. M. James and F. E. Prichard, Practical Physical Chemistry, 3rd ed., Longman,
1974.
3. B. P. Lewitt (ed.), Findlay’s Practical Physical Chemistry, 9th ed., 1973.
4. C. D. Brennan and C. F. H. Tipper, A Laboratory Manual of Experiments in Physical
Chemistry, McGraw-Hill, 1967.
5. C. N. Banwell and E. M. McCash, Fundamentals of Molecular Spectroscopy, 4th Ed.,
Tata-McGraw-Hill, 1994.
6. Introduction to Spectroscopy, Donald L. Pavia, Gary M. Lampman, George S. Kriz,
Thomson Brooks.
7. Spectrometric Identification of Organic Compounds, R. Silverstein, G.C Bassler and
T.C. Morrill, John Wiley and Sons.
8. Organic Spectroscopy, William Kemp, W.H. Freeman & Company.
9. Organic Spectroscopy-Principles and Applications-Jagmohan, Narosa Publication.
10. Organic Spectroscopy, V.R. Dani, Tata McGraw Hill Publishing Co.
11. Spectroscopy of Organic Compounds, P.S. Kalsi, New Age International Ltd.
12. Organic Structures from Spectra, 4th ed., L. D. Field, S. Sternhell and J. R. Kalman,
Wiley.
ELECTIVE COURSES
CHEM 314: EC-I: INTERFACIAL SCIENCE
Unit-I HETEROGENEOUS CATALYSIS [15L]

Adsorption on solid surfaces, Chemisorption at metal surfaces and
oxides, Kinetics of catalyst reactions, structure, preparation and uses
of heterogeneous catalysts, Application of catalysis in energy
conversion, petroleum industry and atmospheric pollution control.
Unit-II CATALYSIS AND GREEN CHEMISTRY [15L]
Comparison of catalyst types, heterogeneous catalysts, zeolites-
composition and structures, synthesis of zeolites, structure
determination, uses of zeolites, zeolites as catalyst, zeolites and the
bulk chemical industry, catalysts in fine chemicals and
pharmaceutical industries, catalytic converters, homogeneous
catalysts -transition metal catalysts with phosphine ligands-
Wilkinson‟s Catalyst, greener Lewis acids, asymmetric catalysis,
phase transfer catalysis, bio catalysis, photo catalysis.
Unit-III NANOCHEMISTRY [15L]
Introduction, Properties of materials & nanomaterials, role of
dimensions in nanomaterials, advantages of nanosize over micron
size, need of surface/encapsulation of nanomaterials, some important
properties of nanomaterials, Techniques for synthesis of
nanomaterials- Physical method and chemical method.
Nanocomposites:
Comparison with conventional composites. Manufacture and
Characteristics of thermoplastic and thermoset nanocomposites
47
products: Fibre reinforced nanocomposites, copolymer / clay
nanocomposites, latex / ZnO nanocomposites, hybrid
nanocomposites, PVC / CaCO3 nanocomposites, etc. Effect of
modifier concentration on structure, mechanical and viscoelastic
properties of nanocomposites, Development and Optimization of
Polymer melt process, Nanocomposites preparation by injection
moulding
Unit-IV SURFACE CHARACTERIZATION TECHNIQUES [15 L]

Principles, instrumentation and applications of:
Electron spectroscopy: ESCA, AUGER and UPS.
Electron microscopy:Scanning electron microscopy, Scanning
probe microscopes: The Scanning Tunneling Microscope, Atomic
force Microscope.
Reference Books:
1.R.P.W.Scott, Tandem Techniques, Wiley India Pvt.Ltd. Reprint 2009.
2.J. Barker, Analytical chemistry for open learning, Mass spectrometry, Wiiley IndiaED.
3.H. J. Arnikar, Essential of Nuclear Chemistry, New Age International, 1995.
4.G. C. Bond, Heterogeneous Catalysis, 2nd ed., Clarendon Press, Oxford, 1987.
5.Mike Lancaster, Green Chemistry: An Introductory Text, Royal Society of Chemistry,
2002.
6.Paul T. Anastas and John C. Warner, Green Chemistry – Theory and Practice, Oxoford
7.Albert S. Matlack, Introduction to Green Chemistry, Marcel Dekker, Inc., 2001.
8.Text/Reference books
9.Novel Nanocrystalline Alloys and Magnetic Nanomaterials- Brian Cantor
10. Nanomaterials Handbook- Yury Gogotsi
11. Encyclopedia of Nanotechnology- Hari Singh Nalwa
12. Introduction to Nanotechnology - Charles P. Poole Jr. and Franks. J. Qwens
13. Microwave Properties of Magnetic Films - Carmine Vittoria.
14. Physics of Magnetism - S. Chikazumi and S.H. Charap
15. Physical Theory of Magnetic Domains - C. Kittel
16. Magnetostriction and Magnetomechanical Effects - E.W. Lee
17. Springer Handbook of Nanotechnology - Bharat Bhusan
18. Chemistry of nanomaterials: Synthesis, properties and applications by CNR Rao
19. Synthesis of Nanostructured Materials –Cao
20. Handbook of Nanoscience, Engineering- Goddard et al
21. Nano Engineering in Science & Technology: An introduction to the world of nano
design by Michael Rieth.
22. Introduction to Solid State Chemistry – A. R. West
23. Nanocomposites Science and Technology - P. M. Ajayan, L.S. Schadler, P. V. Braun
24. Physical Properties of Carbon Nanotubes- R. Saito
25. Carbon Nanotubes (Carbon , Vol 33) - M. Endo, S. Iijima, M.S. Dresselhaus
48
26. The search for novel, superhard materials- Stan Vepr¡ek (Review Article) JVST A,
1999.
CHEM 315: EC-II: SOME SELECTED TOPICS IN PHYSICAL CHEMISTRY

Unit-I COLLOIDAL SCIENCE [15L]
Applied colloids-Surface chemistry and nanocatalysts:
Introduction to the nature of colloidal solution, Surface Tension, Wetting,
Solubilisation, Dispersion, Detergency, contact angle measurement, lotus
effect, Surfactants and Self-assembly, Emulsions and Micro emulsion,
Role of surfactants in synthesis of nanoparticles
Nanocatalysts:
Role of transition metals & metal oxides in homogeneous and
heterogeneous catalysis and their mechanism of catalysis, manufacture of
these catalysts in nano-form and their characterization.
Unit-II GREEN CHEMISTRY [15L]
Principles and Concepts of Green Chemistry:
Sustainable development and green chemistry, Atom economy, examples of
atom economic and atom un-economic reactions, reducing toxicity.
Waste:
Production, Problems and Prevention: Sources of waste from chemical industry,
waste minimization techniques, on-site waste treatment (Physical treatment,
Chemical treatment and bio-treatment plants), and design for degradation:
Degradation and surfactants, DDT, Polymers, rules for degradation.
Organic solvents:
Environmentally benign solutions: solvent free systems, supercritical fluids-
Supercritical carbon dioxide, decaffeination process, ScCO2 as reaction solvent,
Supercritical water, ionic liquids as catalysts and solvents.
Unit-III INSTRUMENTAL METHODS OF CHEMICAL ANALYSIS [15L]
Hyphenated Techniques:
Introduction, need for hyphenation, possible hyphenation, interfacing devices
and applications of the following: GC-MS, GC-IR, MS-MS, LC-MS, ICP-MS
and Spectro-electrochemistry.
Radio-chemical methods: Auto, X-ray and gamma radiography.
Unit-IV ADVANCED INSTRUMENTAL TECHNIQUES (15L)
Electron microprobe method, Reflectance spectroscopy, Chemiluminescence
method, Photoacoustic spectroscopy,
Polarimetry: ORD, CD.
Reference books:
1.Novel Nanocrystalline Alloys and Magnetic Nanomaterials- Brian Cantor
2.Nanomaterials Handbook- Yury Gogotsi
49
3.Encyclopedia of Nanotechnology- Hari Singh Nalwa
4.Introduction to Nanotechnology - Charles P. Poole Jr. and Franks. J. Qwens
5.Microwave Properties of Magnetic Films - Carmine Vittoria.
6.Physics of Magnetism - S. Chikazumi and S.H. Charap
7.Physical Theory of Magnetic Domains - C. Kittel
8.Magnetostriction and Magnetomechanical Effects - E.W. Lee
9.Springer Handbook of Nanotechnology - Bharat Bhusan
10. Chemistry of nanomaterials: Synthesis, properties and applications by CNR Rao
11. Synthesis of Nanostructured Materials –Cao
12. Handbook of Nanoscience, Engineering- Goddard et al
13. Nano Engineering in Science & Technology: An introduction to the world of nano
design by Michael Rieth.
14. Introduction to Solid State Chemistry – A. R. West
15. Nanocomposites Science and Technology - P. M. Ajayan, L.S. Schadler, P. V. Braun
16. Physical Properties of Carbon Nanotubes- R. Saito
17. Carbon Nanotubes (Carbon , Vol 33) - M. Endo, S. Iijima, M.S. Dresselhaus
18. The search for novel, superhard materials- Stan Vepr¡ek (Review Article) JVST A,
1999.
19. Mike Lancaster, Green Chemistry: An Introductory Text, Royal Society of Chemistry,
2002.
20. Paul T. Anastas and John C. Warner, Green Chemistry – Theory and Practice,
Oxoford University Press, 1998.
21. Albert S. Matlack, Introduction to Green Chemistry, Marcel Dekker, Inc., 2001.
22. R.P.W.Scott, Tandem Techniques, Wiley India Pvt.Ltd. Reprint 2009.
23. J. Barker, Analytical chemistry for open learning, Mass spectrometry, Wiiley IndiaED.
24. H. J. Arnikar, Essential of Nuclear Chemistry, New Age International, 1995.
25. G. C. Bond, Heterogeneous Catalysis, 2nd ed., Clarendon Press, Oxford, 1987.
50
SEMESTER-III: INORGANIC CHEMISTRY
Examinations
No. of hours
No. of Continuous End- Total
Course per
Title of the Course Credits Evaluation Sem Marks
Code SEMESTER
Marks Marks
CHEM Solid State
4 60 40 60 100
321 Chemistry - I
Coordination and
CHEM
Bio-Inorganic 4 60 40 60 100
322
Chemistry
Instrumental
CHEM
Methods and 4 60 40 60 100
323
Spectroscopy
CHEM Advances In
324 EC- Inorganic 4 60 40 60 100
II Chemistry
CHEM
Applied Inorganic
325 EC- 4 60 40 60 100
Materials
II
Inorganic
CHEM
Chemistry 4 - - 100 100
326
Practical III
Inorganic
CHEM
Chemistry 4 - - 100 100
327
Practical IV

51
SEMESTER-III: INORGANIC CHEMISTRY
CHEM 321: SOLID STATE CHEMISTRY-I

Unit-I [15L]
(a) Crystal Chemistry:
Structures of the compounds of the types: AB (PbO and CuO), AB2 (-crystabalite,
CaC2 and Cs2O), A2B3 (Cr2O3 and Bi2O3), AB3 (ReO3 and Li3N), ABO3 (relation
between ReO3 and perovskite, BaTiO3 and its polymorphic forms, oxide bronzes,
ilmenite structure), AB2O4 (normal and inverse and random spinel structures),
Pyrochlores.
(b) Linked polyhedra:
Factors affecting linking of polyhedra, Corner sharing: tetrahedral structure
(silicates) and octahedral structure (ReO3), Edge sharing: tetrahedral structure (SiS2)
and octahedral structures of BiI3 and AlCl3, etc.
Unit-II [15L]
(a) Synthesis of Inorganic Materials: Aspects of inorganic synthesis, choosing a
method; Preparation methods: (i) Chemical method (Introduction to ceramic, sol-gel
and precursor methods, Topochemical redox reactions,Ion exchange reactions), (ii)
High pressure methods, (iii) Arc technique and (iv) Skull melting.
(b) Different methods for single crystal growth:
(i) Crystal growth from solution and flux (Flux growth technique).
(ii) Crystal growth from melt- Bridgman and Stockbargar method, Czochralski
technique, Kyropoulos method, Vernuil technique and Zone refining technique.
(iii) Crystal growth from vapor phase: Epitaxial growth methods, chemical vapour
transport.
(c) Thin Film Preparation: (i) Chemical and electrochemical methods,
(ii) Physical methods.
Unit-III [15L]
(a) Solid Solutions: Formation of substitutional, interstitial and complex solid
solutions, mechanistic approach, study of solid solutions by X-ray powder
diffraction and by density measurement.
(b) Liquid Crystals:Introduction and classification of different types of liquid
crystals, polymorphism in liquid crystals, properties and applications of liquid
crystals, inorganic liquid crystals.
Unit-IV[15L]
Crystal defects and non-stoichiometry:
Perfect and imperfect crystals;
Types of defects:
(i) Point defects- Vacancy, Self interstitial, Schottky defect, Frenkel defect,
thermodynamics of formation of these defects (mathematical derivations to find
52
defect concentration and numerical problems expected), defects in non-
stoichiometric compounds: Metal excess defects, Metal deficient defects.
(ii) Line defects- Edge dislocation and Screw dislocation
(iii) Plane defects- Grain boundaries and Stacking faults
Defect clusters, interchanged atoms; Extended atom defects-crystallographic shear
structures, subgrain boundaries and antiphase domains.
CHEM 322: COORDINATION AND BIO-INORGANIC CHEMISTRY

Unit-I INORGANIC PHOTOCHEMISTRY [15L]
Transitions between energy states, decay process, photophysical pathways
(fluorescence and phosphorescence), Jablonski diagram, photochemical pathways
(unimolecular or intramolecular process and bimolecular or intermolecular process),
quantum yield, Kasha‟s rule and Stoke shifts, identification of excited states,
examples of main photochemical processes: non-redox processes (photoisomerization,
photodissociation, photosubstitution), photoredox processes: general aspects and
mechanism.
Photosynthesis reactions (mechanism and salient features of photosynthesis reaction I
and II), light harvesting, solar energy conversion, metal ion sensors, chemosensors,
artificial photosynthesis.
Unit-II MAGNETIC PROPERTIES OF COMPLEXES [15L]

Origin of magnetism, classification of substances according to the magnetic
properties: diamagnetism, paramagnetism, ferromagnetism, antiferromagnetism and
ferrimagnetism. magnetic moment from magnetic susceptibility, Curie equation and
Curie temperature, Curie-Weiss law, Neel temperature, thermal energy and magnetic
moment: multiplet width greater than kT, multiplet width large than kT, temperature
independent paramagnetism, magnetic susceptibility and spin only formula, spin and
orbital contribution to magnetic moment, spin cross-over.
Magnetic properties of transition metal and lanthanide complexes, magnetic
properties of polynuclear and bridged complexes, diamagnetic correction using
Pascal constants and calculation of magnetic moment.
Determination of magnetic susceptibility by Gouy, Faraday, Quinke‟s and NMR
methods.
Unit-IIIELECTRONIC SPECTRA OF COMPLEXES
[15L]
Determination of spectral terms for ground state and excited state using pigeon hole
diagram, energy of terms, Hund‟s rules, spin orbit (L-S) coupling , selection rules and
intensities, crystal field splitting of the terms in ligand field, construction of Orgel
diagram and Tanabe Sugano diagram. Calculation of crystal field parameters (10Dq,
B‟, , o) from electronic absorption spectra of octahedral complexes (d1-d9) using
Tanabe Sugano diagram, equation method and graphical method (whichever
applicable). Comparing the spectra of octahedral, tetrahedral and square planar
complexes of Nickel(II). Charge transfer spectra.
53
Unit-IV BIOINORGANIC CHEMISTRY [15L]
Non-heme iron proteins: Coordination geometry of the metal ion and functions
(enzymes with a mononuclear high-spin Fe(II) centre and with mononuclear Fe (III)
centre).Zn in biological systems: Carbonic anhydrase, protolytic enzymes, e.g.
carboxy peptidase, Zinc finger.Role of metal ions in biological electron transfer
processes.Copper containing proteins and enzymes.Less common ions in biology e.g.
V, Co, Ni. Metallothionines, Biomineralization.
CHEM- 323: INSTRUMENTAL METHODS & SPECTROSCOPY

Unit-I X-RAY DIFFRACTION [15L]
Introduction to X-ray diffraction, diffraction of waves by crystal, particle and solid,
generation of X-rays (K-shell knockout), Bragg condition, Bragg method, Miller
indices, relationship between Miller indices and inter planar spacing. Methods of
diffraction: Laue method, Debye-Scherrer method of X-ray structural analysis of
crystals, advantages of these methods, introduction to JCPDS format, index
reflections, identification of Unit- cells from systematic absences in diffraction
pattern, uses of powder X-ray diffraction, structure of simple lattices and X-ray
intensities, structure factor and its relation to intensity and electron density,
description of the procedure for an X-ray structure analysis, density and crystallite
size determination (numerical problems are expected).
Unit-II [15L]
(a) Electron Diffraction:
Diffraction patterns for single crystal, polycrystalline and amorphous material,
difference between X-ray and electron, experimental technique, applications of
electron diffraction, low energy electron diffraction, reflection high energy electron
diffraction, gas electron diffraction, scattering intensity versus scattering angle and
elucidation of structures of simple gas molecules.
(b) Neutron diffraction:
Properties of neutron, principle of neutron scattering, comparison with X-rays,
advantages of neutron scattering, scattering of neutron by solids and liquids,
experimental technique with essential components, detection of neutrons,
monochromatic technique, time of flight technique, magnetic scattering, applications
of neutron scattering.
Unit-III ELECTRON SPIN RESONANCE SPECTROSCOPY [15L]

Introduction, principle, instrumentation, selection rule, relaxation processes and line
width in ESR transitions, hyperfine splitting, zero field splitting and Kramer‟s
degeneracy, factors affecting g-value. Calculation of g-values with examples.
Intensities of g‖and g  peaks.
Applications of ESR to the study of simple free radicals and metal complexes like
methyl(CH3), cyclopentadienyl (C5H5), hydroxyl methyl (CH2OH), ammonia
54
(NH3), 1,1-diphenyl-2-picryl hydrazyl (DDPH), pyrazine anion (C4N2-), benzene
anion (C6H6-), bis(salicylaldiminato)copper(II), IrCl62-, copper acetate dehydrate and
[VO(5-chlorosalicylaldehyde-aniline)2].
Unit-IV MOSSBAUER SPECTROSCOPY [15L]
Basic principle, recoil energy and Doppler shift. Instrumentation: sources and
absorber; motion devices, detection, reference substances and calibration, isomer
shift, temperature shift, quadrupole interaction, magnetic interaction, electronegativity
and chemical shift.
Applications:
Iron compounds: low spin and high spin Fe(II) and Fe(III) compounds and
complexes, effect of pi-bonding, mono and poly nuclear Iron complexes, spinel
oxides and iron-sulphur proteins.
Tin compounds: tin halides and tin oxides, organotin compounds.
Iodine compounds: I2 and alkali metal iodide compounds.
CHEM 326: INORGANIC CHEMISTRY PRACTICAL-III

I. Separation and estimation of metal ions
1.Separation of Mn and Fe using isoamyl alcohol and estimation of Mn
2.Separation of U and Fe using 8-hydroxyquinoline in chloroform and estimation of U
3.Separation and estimation of Cu(II) and Zn(II) in a mixture using anion exchange resin.
4.Separation and estimation of Ni(II) and Zn(II) in a mixture using anion exchange resin.
5.Separation and estimation of Cu(II) and Ni(II) by forming salicylaldoximinato
complexes by varying pH and characterization of complexes using IR.
II. Analysis of the commercial samples
1.Calcium tablet for its calcium content by complexometric titration.
2.Iron tablet for its iron content colorimetry by 1,10-phenonthroline method.
3.Electral powder for Na/K content flame photometrically.
4.Fasting salt for chloride content conductometrically.
5.Cement for its Iron content by redox titration.
6.Washing soda for its Na2CO3 content by pH metry.
CHEM 327: INORGAIC CHEMISTRY PRACTICAL-IV

III. Coordination Chemistry
1.Determination of Stability constant of [Zn(NH3)4]2+ by potentiometry
2.Determination of Stability constant of [Fe(SCN)]2+ by slope ratio method
3.Determination of CFSE values of [Ti(H2O)6] 3+ and [Ni(H2O)6] 2+ complexes.
4.Determination of Racah parameters and verification of the spectrochemical series for
[Ni(H2O)6] 2+ , [Ni(NH3)6]2+ and [Ni(en)3] 2+ complexes.
55
IV. Synthesis and characterization of Inorganic compounds and materials.
1.Preparation of VO(acac)2 / [Mn(acac)3] and its characterization by IR, conductivity
measurement.
2.Preparation of Hexaamine cobalt (III) chloride and its characterization by IR, and
conductivity measurement.
3.Preparation of MnO2/ZnO/MgO nanoparticles and its characterization by UV-Visible
and XRD techniques.
4.Synthesis of bis(salicyl aldiminato)nickel (II) complex / tris(acetyl
acetonato)aluminium (III) complex and its characterization using IR and NMR.
5.Synthesis of bis(salicyl aldiminato)copper (II) complex and its characterization by IR
and ESR.
6.Synthesis of calcium oxalate/magnesium oxalate and its characterization by TGA/DTA.
7.Synthesis of Prussian blue and its characterization by Mössbauer spectra and cyclic
voltammetry.
8.Solid phase synthesis of trans-bis(glycinato)copper(II) and its characterization by IR,
and conductivity measurement.
ELECTIVE COURSES
CHEM 324: EC-I: ADVANCES IN INORGANIC CHEMISTRY
Unit-I CHEMISTRY OF GROUP 13 & 14 ELEMENTS
[15L]
Introduction to physical and chemical properties of group 13 and 14 elements.
Preparations of various compounds of Al, Ga, In, Tl, Si, Ge, Sn and Pb with special
emphasis on hydrides, oxides, halides, sulphides and coordination compounds.
Unit-II
(a) Chemistry of Group 15 and 16 elements: [15L]
Introduction to physical and chemical properties of group 15 and 16 elements.
eparations of various compounds of P, As, Sb, Bi, S, Se, and Te, with special
emphasis on hydrides, oxides, halides, sulphides, carbides, study of metal nitrides,
phosphides, arsenides, antimonides and bismuthides and its applications. Preparation
and uses of important compounds like phosphine, azide, hydrazine and
hydroxylamine; study of metal sulphides, selenides, tellurides and polonides, ring and
cluster compounds, polyanions, polycations and S-N compounds.
(b) Chemistry of Group 17 elements:
Introduction to physical and chemical properties of group 17 elements. reactivity,
uses, special properties of fluorine compounds, interhalogens, cationic interhalogens,
halogen complex and polyhalides, halogen oxides and fluorocarbons.
56
Unit-III
[15L]
(a) Preparation of coordination compounds by:
(i) Addition reaction, (ii) Substitution reaction, (iii) Redox reaction, (iv) Thermal
dissociation of solid complexes, (v) Reaction in the absence of oxygen, (vi) Reaction
of coordinated ligands, (vii) Trans effect.
(b) Steoreochemistry, Chirality and Fluxionality of coordination

compoundswith:
Higher coordination numbers, Isomerism and polymorphism in coordination
compounds
(c) Crystal Engineering: Metal organic frameworks (MOFs):
Strategies in Coordination Chemistry (Node-and-SpacerApproach), General analysis
of Framework Structures (1D, 2D and 3D framework structures), MOFs with
Polydentate ligands. Applications of MOFs.
Unit-IV METALLURGY [15L]

Occurrence, extraction and metallurgy of Zirconium, Hafnium, Niobium, Tantalum,
Palladium and Platinum. Physical and chemical properties and applications of these
metals, compounds of these metals, alloys and their uses.
CHEM-325: EC-II: APPLIED INORGANIC MATERIALS

Unit-I
[15L]
(a) Inorganic Materials:
Classification, manufacture and applications of (i) Inorganic fibers, and (ii) Inorganic
fillers. Study of (i) Condensed phosphates, and (ii) Coordination polymers.
(b) Preparation, properties and uses of industrially important chemicals: Sodium
peroxide, sodium hydrosulphide, sodium thio sulphate, bleaching powder, hydrogen
peroxide, Sodium hydroxide, chlorine and lime.
Unit-II [15L]
Supramolecular chemistry:
Definitions, intermolecular bonds, concepts and perspectives, cationic recognition,
anionic recognition, neutral molecular recognition: self-assembly concept and its
application in molecular and supramolecualar chemistry, supra molecular devices and
machines.
Inorganic Pharmaceuticals:
Lithium drugs, gold antiarithritic drugs, bismuth drugs in treatment of gastric ulcers,
Cyclams as anti-HIV agents, radio diagnostic agents, contrast agents for X-ray and
MRI imaging.
57
Unit-III MANUFACTURING & APPLICATIONS OF THE FOLLOWING
[15L]
(i)Fertilizers and nutrients (ii) Glass (iii) Paints and pigments (iv) Zeolites: synthesis,
characterization, determination of surface acidity, shape selectivity, characterizations
and applications.
Unit-IV MISCELLANEOUS TOPICS [15L]

(i)Isopoly and heteropoly acids (ii) Intercalation compounds,(iii) Ceramics and
refractory materials (iv) Cement (v) Inorganic explosives (lead azide and mercury
fulminate).
Reference books:
CHEM-321:
Unit-I:
1. Ulrich Muller, Inorganic structural chemistry, 2nd edition, Wiley (2006).
2. A. F. Wells, Structural inorganic chemistry, 5th edition, Clarendon press, Oxford (1984).
3. A. R. West, Solid state chemistry and its chemical applications, John Wiley & Sons,
(1984).
Unit-II:
(1984).
2. Lesley E. Smart and Elaine A. Moore, Solid state chemistry – An introduction, 3rd Ed.,
Taylor and Francis, (2005).
3. C. N. R. Rao and J. Gopalakrishnan, New directions in solid state chemistry, Cambridge
university press, (1986).
Unit-III:
(1984).
2. C. N. R. Rao and J. Gopalakrishnan, New directions in solid state chemistry, Cambridge
university press, (1986).
Unit-IV
(1984).
2. H. V. Keer, Principles of the solid state, Wiley Eastern Ltd, (1994).
3. Lesley E. Smart and Elaine A. Moore, Solid state chemistry – An introduction, 3rd Ed.
CHEM 322:
Unit-I:
1. J. R. Gispert, Coordination Chemistry, Wiley-VCH (2008).
2. D. Banerjea, Coordination chemistry, 3rd edition, Asian Books Pvt. Ltd. (2009).
3. R. Gopalan and V. Ramalingam, Concise coordination chemistry, Vikas Publising House
Pvt. Ltd. (2007).
58
4. Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt,. Ltd. (2002).
5. B. Douglas, D. McDaniel and J. Alexander, Concepts and models of inorganic chemistry,
3rd editions, John Wiley & Sons, Inc.(2001).
Unit-II:
1. R. A. Dutta & A. Syamal, Elements of magnetochemistry, 2nd edition, Affiliated East-
West Press Pvt. Ltd. (1993).
2. D. Banerjea, Coordination chemistry, 3rd edition, Asian Books Pvt. Ltd. (2009).
Pvt. Ltd. (2007).
Unit-III:
1. J. E. Huheey, E. A. Keiter, R. L. Keiter and O. K. Medhi, Inorganic chemistry- Principles
of structure and reactivity, 4th edition, Pearson (2006).
2. A. B. P. Lever, Inorganic electronic spectroscopy, Elsevier Publishing Company (1968).
Pvt. Ltd. (2007).
4. J. E. House, Inorganic chemistry, Academic press, 2nd edition, 2013.
Unit-IV:
1. S. J. Lippard and J. M. Berg, Principles of bioinorganic chemistry, University Science
Publications, Mill Valley, Caligronic, (1994).
2. R. R. Crichton, Biological Inorganic Chemistry, A new introduction to molecular
structure and function, 2nd Edition, Elsevier, (2012).
3. I. Bertini, H. B. Gray, S. J. Lippard and J. S. Valentine, Bioinorganic chemistry, First
South Indian Ed., Viva Books, New Delhi, (1998).
4. G. N. Mukherjee and A. Das, Elements of bioinorganic chemistry, Dhuri and Sons,
Calcutta, (1988).
5. R. W. Hay, Bioinorganic chemistry, Ellis Harwood, England, (1984).
6. J. A. Cowan, Inorganic biochemistry-An introduction, VCH Publication, (1993).
CHEM 323:
Unit-I-IV:
1. Lesley E. Smart and Elaine A. Moore, Solid state chemistry – An introduction, 3rd Ed.,
2. Fmiza Hammer, Inorganic spectroscopy and related topics, Sarup & Sons (2008).
3. R. S. Drago, Physical methods for Chemists, 2nd edition, Saunders college publishing
(1992).
4. R. S. Drago, Physical methods in Inorganic chemistry, Affiliated East-West Press Pvt.
Ltd; New Delhi.
5. R. A. Scott and C. M. Lukehart, Applications of physical methods to inorganic and
bioinorganic chemistry, John Wiley & Sons Ltd. (2007).
6. D. N. Sathyanarayana, Introduction to magnetic resonance spectroscopy ESR, NMR,
NQR, I. K. Intenational publishing house pvt. Ltd. (2009).
7. K. Burger, Coordination chemistry: Experimental methods, London Butterworths, (1973).
8. R. V. Parish, NMR, NQR, EPR and Mossbauer spectroscopy in Inorganic Chemistry,
Ellis Horwood. (1990).
59
Reference books for practicals
CHEM326:
Unit-I:
1.Gopalan, Universities Press India Pvt.Ltd. Inorganic Chemistry for Undergraduates,
(2009).
2.P. L. Soni, Textbook of Inorganic Chemistry. Sultan Chand & Sons Publisher, 15th Edition
(1984).
3.J. D. Lee, 5thEdn.,Concise Inorganic Chemistry, ELBS, (2010).
4.M. Weller, T. Overton, J. Rourke and F. Armstrong, Inorganic chemistry, 6thedition,
Oxford University Press (2015).
Unit-II:
(1984).
Unit-III:
1.S. F. A. Kettle, Coordination compounds, Thomas Nelson and Sons Ltd. (1975).
2.D. Banerjea, Coordination chemistry, 3rd edition, Asian Books Pvt. Ltd. (2009).
3.R. Gopalan and V. Ramalingam, Concise coordination chemistry, Vikas Publising House
Pvt. Ltd. (2007).
4.J. R. Gispert, Coordination Chemistry, Wiley-VCH (2008).
Unit-IV:
1.R.Gopalan, Universities Press India Pvt.Ltd. Inorganic Chemistry for Undergraduates,
(2009).
(1984).
CHEM 327:
Unit-I:
1.J. E. Huheey, E. A. Keiter, R. L. Keiter and O. K. Medhi, Inorganic chemistry- Principles
(1984).
Unit-II:
1.J. R. Gispert, Coordination Chemistry, Wiley-VCH (2008).
2.J. M. Lehn, Supramolecular Chemistry: Concepts and Perspectives, VCH, 38 Weinheim,
(1995).
3.D. F. Shriver and P. W. Atkins, Inorganic chemistry, 3rd edition, Oxford University Press
(1999).
4.J. H. Block, E. B. Roche, T. O. Soine and C. O. Wilson, Inorganic medicinal and
pharmaceutical chemistry, Lea and Febiger, (1974).
60
Unit-III:
(1984).
2.Lesley E. Smart and Elaine A. Moore, Solid state chemistry – An introduction, 3rd Ed.,
Unit-IV:
(1984).
Reference books for practicals:
1. A. I. Vogel, Quantitative Inorganic Analysis.
2. J. D. Woolins, Inorganic Experiments.
3. Palmer, Inorganic Preparations.
4. G. Raj, Advanced Practical Inorganic Chemistry.
5. J. E. House, Inorganic chemistry, Academic press, 2nd edition, (2013).
61
SEMESTER-III: ORGANIC CHEMISTRY
Examination
No. of
Contin
hours
No. of uous End-
Course per Total Marks
Title of the Course Credits Evalua Sem
Code SEMES-
tion Marks
TER
Marks
Photochemistry,
CHEM Stereochemistry, Physical
4 60 40 60 100
331 Organic Chemistry, and
Pericyclic Reactions
CHEM Ylids, -C-H Activation And

Reactions, Radicals and 4 60 40 60 100
332
Organometallic Chemistry
CHEM Heterocyclic Chemistry and
Advanced Spectroscopic 4 60 40 60 100
333
Techniques-I
CHEM Medicinal, Green &
4 60 40 60 100
334 EC-I Bioorganic Chemistry
CHEM Enzymes, Coenzymes &
4 60 40 60 100
335 EC-II Biogenesis
CHEM Organic Chemistry Practical
4 - - 100 100
336 III
CHEM Organic Chemistry Practical
4 - - 100 100
337 IV

62
SEMESTER-III: ORGANIC CHEMISTRY
CHEM 331: PHOTOCHEMISTRY, STEREOCHEMISTRY, PHYSICAL ORGANIC

CHEMISTRY, AND PERICYCLIC REACTIONS
Unit-IPHOTOCHEMISTRY [15L]
1.Photochemistry:
1.1 General Principles-Importance and applications of photochemical processes, Mechanism
of absorption of photochemically relevant radiation, Excitation and deactivation of
molecules, Electronic transitions and states, Selection rules, notations, types and
characteristics, Electron energy transfer,photosensitization and quenching processes. [3L]
1.2 Photochemistry of carbonyl compounds, *, n * transitions, Norrish type-I and
Norrish type-II cleavages, Patterno-Buchhi reactions, photoreductions, photochemistry of
enones, cyclohexadienones, rearrangements of , -unstaurated ketones.[4L]
1.3 Photochemistry of unsaturated system-olefins, cis-trans isomerizations and, Di- methane

rearrangement.[3L]
1.4 Photochemistry of arenes, 1, 2; 1,3 and 1,4 additions. [1L]
1.5 Singlet oxygen and photooxygenation reactions. [1L]
1.6 Intramolecular Rearrangements: Rearrangements with trimesityl compound to enol
ether, o-nitrobenzaldehyde to o-Nitrosobenzoic acid.
Determination of photochemical mechanisms:
1. Use of emission (fluorescence and phosphorescence) and absorption spectroscopy. Energy
and life time of singlet and triplet states.
2. The study of quantum yields: primary quantum yields, product quantum yields. [3L]
Unit-IISTEREOCHEMISTRY [15L]
2.1 Stereochemistry of decalins, hydrindanes, steroids and Bridged ring compounds, Bredt‟s
rule,discussion on non-classical carbocation [4L]
2.2 Transannular effects, Addition reactions, elimination reactions [2L]
2.3 Classification of point groups based on symmetry elements with appropriate examples
[non-mathematical treatment] [2L]
2.4 Molecular dissymmetry and chiroptical properties: [4L]
Linearly and circularly polarized light, Circular birefringence and Circular dichroism,
ORD and CD curves and their applications, The Octant rule and its applications,
Applications of CD in conformational studies of biopolymers.
2.5 Structures, symmetry and synthesis of 3-prismane and cubane: [3L]
Reactions of cubane and its derivatives, Structures and symmetry of 4/5/6 prismanes and
general methods of synthesis of Helicenes and their chiral applications.
63
Unit-IIIREACTIVE INTERMEDIATES & PHYSICAL ORGANIC CHEMISTRY [15
L]
3.1 Organic reactive intermediates: [8L]
Methods of generation, Structure, Stability and important reactions of Carbocations
[including NGP and non-classical carbocations], Carbenes, Arynes, Nitrenes, ketenes.
3.2 Acid-base catalysis-General and specific acid and base catalysed reactions, Acidity
functions and acidity strength, Reaction rates and acidity scales, Mechanism of acid-base
catalysis. [3L]
3.3 Potential Energy surfaces, Bell-Evans Polanyi principle, Marcus theory, Curtin-Hammett
principle [2L]
3.4 Kinetic methods:
Determination of reaction order and rate constants, Empirical rate equations for parallel
reactions, Sequential reactions. [2L]
Unit-IVPERICYCLIC REACTIONS[15L]
4.1 Role of FMOs in organic reactivity:
Hard and Soft electrophiles and nucleophiles, Ambident nucleophiles, ambident
electrophiles, the  effect. [3L]
4.2 Classification of pericyclic reactions: [1L]
Thermal and photochemical reactions
4.3 Three approaches: [2L]
(1) Conservation of orbital symmetry/Correlation Diagram
(2) Frontier Molecular Orbital approach [FMO] and (3) Aromatic [Huckel and Mobius]
Transition state approach.
4.4 Cycloaddition reactions: [3L]
4n and (4n+2)  electron systems. Diels-Alder reactions, 1,3-Dipolar cycloadditions and
Cheletropic reactions, retro-Diels-Alder reaction. Rates of Diels –Alder reaction based on
FMOs; regioselectivity, periselectivity and site selectivity in Diels-Alder reactions.
4.5 Electrocyclic reactions: [2L]
Conrotatory and disrotatory motions, 4n and (4n+2)  electron systems and other systems.
4.6 Sigmatropic rearrangements: [3L]
H-Shifts and C-shifts, supra and antarafacial migrations. Retention and inversion of
configurations. Cope and Claisen rearrangements
4.7 Diimide reduction reactions, *Group transfer reactions [1L]
CHEM 332: YLIDS, α-C-H ACTIVATION AND REACTIONS, RADICALS AND

ORGANOMETALLIC CHEMISTRY
Unit-IYLIDS, -C-H ACTIVATION & REACTIONS [15L]
1.1. Methods of preparations, structures and reactivity comparison of phosphorus, sulfur and
nitrogen ylides, Reactions of P-, S- and N- ylides with carbonyl compounds and other
substrates, including mechanism, stereochemistry and applications in natural product
synthesis of Wittig reaction.
64
1.2. - C-H activation by nitro, sulfoxide, sulfone and phosphonate groups: generation of
carbanions by strong bases (LDA/n-BuLi) and applications in C-C bond formations.
Vicarious nucleophilic substitutions.
1.3. Bamford-Stevens Reaction, Julia-Kocienski Olefination, Ramberg-Bäcklund Reaction,
Staudinger Reaction, Bestmann-Ohira Reagent, Barton-Kellogg olefination, Steven‟s
rearrangement, Pummerer sulfoxide rearrangement
Unit-IIRADICALS IN ORGANIC SYNTHESIS [15 L]
2.1.General aspects:
Electrophilic and nucleophilic radicals and their reactivities with -rich/deficient olefins.
2.2.Inter- and intramolecular aliphatic C-C bond formation via mercury hydride, tin hydride,
carbon hydride, thio donor (Barton‟s radical decarboxylation reaction).
2.3.Cleavage of C-X, C-Sn, C-Co and C-S bonds in the generation of radicals.
2.4.Trapping by electron transfer reactions using Mn(OAc)3.
2.5.Radical–Radical processes:
oxidative couplings, single electron oxidation of Carbanions to generate radicals,
dehydrodimerization and Reductive couplings.
2.6.C-C bond formation in aromatics:
Introduction, radical reactions on aromatics, electrophilic radical reactions, nucleophilic
radicals, Radical reactions on heteroaromatics–alkylations and acylations.
2.7.Hunsdiecker halodecarboxylation, Barton-McCombie alcohol deoxygenation, Kuivila-
Beckwith and Stork radical dehalogenation/cyclization, Bergman and Myers-Saito
Cycloaromatization.
Unit-IIIMETALS/NON-METALS IN ORGANIC SYNTHESIS [15L]
3.1.Organolithium reagents, Prep and synthetic applications, including directed metallation.
Organocupurate reagents.
3.2.Applications of boron: generation of diborane, hydroboration/oxidation of alkenes,
alkynes – mechanism, regiochemistry and stereochemistry. Asymmetric hydroboration
using chiral borane reagents, functional groups reduction by diborane.
3.3.Mercury in organic synthesis: Oxymercuration-demercuration of alkenes, mechanism and
regiochemistry, solvomercuration and intramolecular mercuration. Mercuration of
aromatics and transformation of aryl-mercurals to aryl halides.
3.4.Organosilicons: Important features of silicon governing the reactivity of C-Si compounds:
Preparation and important C-C bond forming reactions of alkyl silanes, alkenyl silanes,
aryl silanes and allyl silanes. Silyl enol ethers as enolate precursors. Iodo trialkyl silane
and tralkylsilylcyanide in organic synthesis.
3.5.Organotin compounds: Preparation of alkenyl/aryl and allyl tin compounds and their
acylation and Michael reactions.
3.6.Selenium in organic synthesis: preparation of selenols/selenoxide, selenoxide elimination
to create unsaturation, selenoxide and seleno-acetals as -C-H activating groups.
Unit-IVTRANSITION & RARE-EARTH METALS IN ORGAINC SYNTHESIS [15L]
4.1.Basic concepts, 18 electron rule, oxidative addition, reductive elimination, substitution.
4.2.Pd and Rh in organic synthesis:
65
π-bonding of Pd and Rh with olefins, applications in C-C bond formations including Wacker
process, Heck reaction, Negishi coupling reactions, Carbonylation, hydroformylation,
decarbonylation, olefin isomerism, aryl amination using Pd reagents. Olefin metathesis
(RCM) using catalysis.
4.3.Applications of nickel, cobalt, iron and chromium carbonyls in organic synthesis
4.4.Selected applications of Samarium iodide, and Cerium (IV), in organic synthesis.
4.5.Eu(OTf)3 and Sc(OTf)3 as efficient, water tolerant Lewis acid catalysts in aldol
condensation, Micheal reactions, Diels-Alder and aza-Diels-Alder reactions, acylation
reactions .
CHEM 333: HETEROCYCLIC CHEMISTRY AND ADVANCED SPECTROSCOPIC

TECHNIQUES-I
Unit-IHETEROCYCLIC CHEMISTRY-I [15L]
1.1Introduction, Classification, IUPAC and common names of mono-and bicyclic fused
Heteroaromatic compounds. [5L]
1.2Reactivity, important general methods of synthesis and selected applications of the
following heterocycles: [10L]
Pyrazole, imidazole, oxazole, isoxazole, thiazole, benzimidazole, benzoxazole,
benzthiazole,pyridine and pyridine N-oxide.
Unit-IIHETEROCYCLIC CHEMISTRY-II [15L]
2.1.Reactivity, important general methods of synthesis and selected applications of
the following Heterocycles:
Pyridazine, pyrimidine, pyrazine, oxazine, quinoline, isoquinoline, coumarin, indole,
purine, s-triazine, benzodiazepine,piperidine, morpholine.
Unit-IIIADVANCED SPECTROSCOPIC TECHNIQUES-I [15L]
3.1.FT-IR Spectroscopy: Principle and applications [2L]
3.2.NMR Spectroscopy: Relaxation phenomenon and relaxation time, First order, higher
order spectra and their simplifications, Double resonance,NOE,NOE difference
spectroscopy and chemical shift reagents. [3L]
3.3.Second order spectra: Spin system notation, AB, AX, AB2-AX2, ABX, AMX and A2B2-
A2X2 spin system with suitable examples, Coupling in aromatic and heteroaromatic
systems,long range coupling. [2L]
3.4.Spectra of diastereotopic systems [1L]
3.5.ESR: Fundamentals and applications [2L]
3.6.Fluorescence Spectroscopy : Principles and applications [2L]
3.7.Problems [3L]
Unit-IVADVANCED SPECTROSCOPIC TECHNIQUES-II [15L]
4.1.FT-NMR:Pulse sequences,pulse widths,spins and magnetisation vectors. [1L]
13 13 13 13
4.2. C -NMR: C nucleus, C- chemical shifts,Calculation of C- chemical shifts, proton
coupled 13 C - spectra,13C spectra Integration, proton decoupled 13C- spectra. Off- resonance
decoupling,DEPT technique, heteronuclear coupling of carbon to 19F and 31P [3L]
19
4.3. F-NMR: Principles and applications [2L]
31
4.4. P- NMR: Principles and applications [2L]
4.5.Two dimensional NMR:
66
Introduction, COSY technique and overview of COSY experiment, how to read COSY
spetra, HETCOR technique and overview of the HETCOR experiment, how to read
HETCOR spectra. [2L]
4.6.NOESY, ROESY, HMBC, INADEQUATE techniques [2L]
4.7. Problems [2L]
4.8. Applications of NMR in medicine [1L]
CHEM 336: ORGANIC CHEMISTRY PRACTICAL-III

Separation and analysis of Ternary mixture: (Minimum 8)
A three component mixture of solids and liquids and belonging to same or different
chemical classes. Detection and separation of ternary mixture of same or different
physical states (solids and liquids) and same or different chemical classes. [Mixture
with same chemical classes separable by physical methods can be given.
Identification of all three components with preparation of derivatives for two of the
components is expected.
CHEM 337: ORGANIC CHEMISTRY PRACTICAL-IV

One step preparations with column chromatography / steam distillation purification
step OR two step preparations: (Minimum 8)
1. 1-Nitronaphthalene from naphthalene [purification by steam distillation].

2. P-Nitrophenol from phenol. [purification by column chromatography].
3. Acetyl ferrocene from ferrocene [purification by column chromatography].
4. M-Nitroaniline from m-dinitrobenzene [purification by column chromatography].
5. Flourenone from flourene [purification by column chromatography].
6. Anthracene-anthraquinone –anthrone
7. Benzoin-benzil-benzillic acid.
8. Acetophenone-acetophenone phenyl hyrazone-2-phenyl indole.
9. 2-Naphthol to 1-phenylazo-2-naphthol to 1-amino-2-naphthol.
10.Cyclohexanone- cyclohexanone oxime-caprolactum
11.Gluocose-1,2,5,6-Di-O-diisopropylidine-α-D-glucofuranose
ELECTIVE COURSES
CHEM 334: EC-I: MEDICINAL, GREEN AND
BIOORGANIC CHEMISTRY
Unit-IDRUG DISCOVERY/DESIGN & DEVELOPMENT & SYNTHESIS–I [15L]
1.1General introduction to discovery of new drugs: [6L]
Drug discovery without a Lead: Penicillin and Librium.
Lead discovery:
Random screening, non-random (or Targeted) screening
Drug metabolism studies, clinical observations, Rational approach to lead discovery.
67
1.2Lead Modification: Drug design and Development [6L]
Identification of pharmacophore, functional group modification, structure activity
relationship, privileged structures and drug like molecules. Structural modification to
increase potency and therapeutic index: Homologation. Chain branching, ring chain
transformation, bioisosterism
1.3 Combinatorial Chemistry: [3L]
General concepts, split synthesis, peptide libraries, encoding combinatorial libraries.
Unit-IIDRUG DISCOVERY/DESIGN & DEVELOPMENT & SYNTHESIS–II [15L]
2.1Synthesis and application of following drugs: Atorvastatin, Linezolide, Nateglinide, S-
omeprazole, Ramipril, Zidovudine (AZT). [10L]
2.2.Steric effect:
2.3.The Taft and other equations, methods used to correct regression parameters with
biological activity.
Hansch analysis: A linear multiple regression analysis [5L]
Unit-IIIGREEN CHEMISTRY & ENZYMATIC PROCESSES [15L]
3.1.Green Chemistry:
Introduction, Basic principles of green chemistry with applications. [3L]
3.2.Examples of green synthesis/reaction
Green Starting materials
Green Reagents
Green Solvents and reaction conditions (Solvent replacement table, Supercritical fluids)
Green Catalysis(Traditional processes and green one)
Synthesis of Ibuprofen, Adipic Acid. [7L]
3.2.Enzyme catalyzed Organic Reactions: Hydrolysis, Hydroxylation, Oxidation and
Reductions. [5L]
Unit-IVBIOORGANIC CHEMISTRY [15L]
4.1.Nucleic acids: [10L]
Structure and function of DNA and RNA, genetic code, protein biosynthesis,mutation
4.2.Recombinant DNA synthesis: [5L]
Phosphodiester, Phosphotriester, Phasphoramidite and H- phosphonate approach
including solid phase approach.
CHEM 335: EC-II: ENZYMES, COENZYMES AND BIOGENESIS

Unit-IENZYMES-I [15L]
1.1.Introduction and classification of enzymes.
Properties of enzymes: i) Enzyme efficiency ii) Enzyme specificity. [5L]
1.2.Enzyme Kinetics:
i) Effect of substrate ii) Other factors affection enzyme kinetics such as temperature, pH etc.
[5L]
1.3.Enzymes as Catalyst:
Specificity of Enzyme Catalyzed Reactions, Rate accelerators. [5L]
68
Unit-IIENZYMES-II [15L]
2.1.(i) Mechanism of enzyme action and Synthetic approach of enzyme, Mechanism of
alcoholic fermentation.
(ii) Role of main enzymes involved in the synthesis and breakdown of glycogen.
(iii)Glycogen store diseases caused by enzyme deficiency [7L]
2.2.Chemical nature of selected enzymes: Co-carboxylase, Coenzyme A, Riboflavin
phosphate, UDPG, Glucose-1, 6-diphoaphate. [6L]
2.3.Bradford assay for enzyme characterization [2L]
Unit-IIICOENZYMES[15L]
3.1.Chemistry of Coenzymes: structures, mechanism of action and bio-modeling studies of
the following coenzymes- thiamine pyrophosphate, lipoic acid, nicotinamide adenine
dinucleotide, flavin adenine dinucleotide, pyridoxal phosphate, Vitamin B12. [12L]
3.2.Oxygen activation in biological systems with reference to Cytochromes. [3L]
Unit-IVBIOGENESIS & BIOSYNTHESES OF NATURAL PRODUCTS [15L]
4.1.Biogenesis: Precursors, Primary and secondary metabolites, Acetate hypothesis.
Mevalonate and Shikimic acid pathways. [5L]
4.2.Biosynthesis: amino acids, alkaloids, steroids and terpenoids. [5L]
4.3.Biosynthesis of selected natural products: L-Tryptophan, Cephaline, Cholesterol,
Ephedrine, Citranellal [5L]
69
SEMESTER-III: ANALYTICAL CHEMISTRY
No. of Examination
hours
No. of Continuous Total
Course per End-Sem
Title of the Course Credits Evaluation Marks
Code SEMES Marks
-TER Marks
CHEM 341 Separation Techniques 4 60 40 60 100

CHEM 342 Spectroscopic Techniques 4 60 40 60 100
Electrochemical
Techniques Sensors and
CHEM 343 4 60 40 60 100
Environmental
Management
Special Topics in
CHEM 344
Analytical Chemistry- 4 60 40 60 100
EC-II
I
Special Topics in
CHEM 345
Analytical Chemistry- 4 60 40 60 100
EC-II
II
Analytical Chemistry
CHEM 346 4 - - 100 100
Practical III
Analytical Chemistry
CHEM 347 4 - - 100 100
Practical IV

70
SEMESTER-III: ANALYTICAL CHEMISTRY
CHEM 341: SEPARATION TECHNIQUES

Unit-I [15L]
1.1 Solvent Extraction: Extraction equilibria of Liquid cation exchangers, liquid
anion exchangers and crown ethers. Nature of extracted species. Parameters
influencing extraction including e.g. role of diluents, aggregation, third
phase formation and counter ion. Applications of liquid-liquid extraction in
metallurgy and biotechnology.
Unit-II [15L]
2.1 Supercritical Fluid Extraction: [5L]
Principles, instrumentation and applications.
2.2 Solid Phase Micro Extraction: Sorbents, methodology, applications and [3L]
automation.
2.3 Ion Exchange Chromatography: Synthetic resin based ion exchangers. Type [7L]
of resin matrices. Breakthrough volume and capacity. Inorganic ion
exchangers, chelating ion exchangers, imprinted functional polymers, ligand
exchange for separation of organic molecules and enantiomers.
3.1 Unit-III [15L]
Ion Chromatography: [7L]
Suppressor reactions, instrumentation, standard operating conditions,
singlecolumn ion chromatography, coupled ion-chromatography.
Applications.
3.2 Size Exclusion Chromatography: [4L]
Theory, type of packings, molecular mass determination. Large scale
purification of large bio molecules.
3.3 Super Critical Fluid Chromatography: [4L]
Instrumentation, effect of pressure, mobile phases, comparison with LC and
GC. Applications.
4.1 Unit-IV [15L]
Method development in HPLC: [7L]
Selection of stationary phases and mobile phases, gradient elution, polarity
index, comparison of detectors, hybrid columns, chiral separations and
PLRP-S. Concept of Preparative chromatography and UPLC.
4.2 Membrane based Separations: [8L]
Principles and applications of microfiltration, ultrafiltration, reverse
osmosis, dialysis and electrodialysis. Liquid membranes.
71
Reference books:
1. Solvent Extraction Separation of Elements with Liquid Ion Exchangers, S. M.
Khopkar, New Age Science Ltd., (2009).
2. Solvent Extraction Principles and Practice, 2nd Edition, J. Rydberg, M. Cox, C.
Musikas, G. Choppin, Marcel Dekker, New York, (2004).
3. Solvent Extraction in Biotechnology, K. Schugert, Springer-Verlag Berlin Heidelberg,
New York, (1994).
4. Solvent Extraction Chemistry, T. Sekine, Y. Hasegawa, Marcel Dekker, New York,
(1977).
5. Supercritical Fluid Extraction, L. Taylor, WILEY Publishers, New York, (1996).
6. Membrane Separation Process, K. Nath, PHI learning Pvt. Ltd., (2008).
7. Analytical Separation Science (Volume 1-5), J. L. Anderson, A. Berthod, V. Pino, A.
M. Stalcup, WILEY-VCH, (2015).
8. Ion Exchange Materials Properties and Applications, 1st Edition, A. A. Zagorodni,
Elsevier, (2007).
9. Introduction to Instrumental Analysis, R. D. Brown, McGraw Hill, (1987).
10.Instrumental Methods of Analysis , H. H. Willard, L. L. Meritt, J. A. Dean, Affiliated
East-West Press, (1977).
11.Selection of the HPLC Method in Chemical Analysis, S. C. Moldoveanu, V. David,
Elsevier, (2017).
12.Principles of Instrumental Analysis, D. A. Skoog, F. James Hollier, T. A. Naiman,
Harcourt College Publishers, Harcourt India Pvt. Ltd., (1998).
13.Chemical Separations and Measurements Introduction to Separation Science, B. L.
Kauger, L. R. Snyder, C. Howath, John Wiley, New York, (1973).
CHEM- 342: SPECTROSCOPIC TECHNIQUES

Unit-I: [15]
1.1 Infra-Red Spectroscopy:
Characteristic vibrational frequencies of alkanes, alkenes, alkynes, aromatic [10L]
compounds, alcohols, ethers, phenols and amines. Study of vibrational
frequencies of carbonyl compounds (ketones, aldehydes, esters, amides, acids,
anhydrides, lactones, lactams and conjugated carbonyl compounds), Effect of
hydrogen bonding, Solvent effect on vibrational frequencies, Overtones and
Combination bands.
1.2 Raman Spectroscopy: [5L]
Classical and Quantum theory of Raman Scattering, Experimental Methods,
Correlation of Infrared and Raman Spectra, Normal Modes of vibrations.
Unit-II: [15]
2.1 Nuclear Magnetic Resonance Spectroscopy (1H-NMR): [8L]
Chemical and magnetic equivalent protons, Chemical shift, Spin-spin coupling,
Different types of coupling, Factors affecting to coupling constant, Karplus
equation, Spin system (AB, AX, ABX, AMX), Shift reagents, Nuclear
Overhouser Effect (NOE).
72
2.2 Nuclear Magnetic Resonance Spectroscopy (13C NMR): [7L]
Introduction, Chemical shift of aliphatic, olefinic, alkyne, aromatic,
heteroaromatic and carbonyl carbon, Effect of substituents on chemical shift.
Unit-III: [15]
3.1 Mass spectrometry:
Introduction, Ion analysis, Ion abundance, Factors affecting to the
fragmentation, Fragmentation of different functional groups, Molecular ion
peak, Isotopic peak, Metastable peak, Nitrogen rule, MacLafferty
rearrangement, Retro-Diels-Alder reaction.
Unit-IV: [15L]
4.1 Problems: [10L]
1 13
Based on joint applications of IR, H NMR, C NMR, and Mass spectrometric
techniques.
4.2 Electron Spin Resonance Spectroscopy:

Introduction, Principle of ESR spectroscopy, Instrumental aspect, The „g‟ [5L]
factor, Factors affecting to the „g‟ value, Hyperfine splitting in various
structures, Zero field splitting, Kramers degeneracy, Applications to free
radicals and transition metal complexes.
Reference books:
1. Donald Pavia; Gary Lampman, Introduction to Spectroscopy, 4th Edition.
2. Barbara H. Stuart, Infra-red Spectroscopy: Fundamentals and Applications.
3. R. M. Silverstein; F. X. Webster, Spectroscopic Identification of Organic Compounds,
6th Edition, John Wiley and Sons.
4. William Kemp, Organic Spectroscopy
5. Harald Gunther, NMR Spectroscopy, Basic principles, Concepts and Applications in
Chemistry.
6. Atta-Ur-Rehman; Verlag; Nuclear Magnetic Resonance: Basic Principles (1986).
7. Phillip Crews; Rodriguez; Jaspars; Organic structure Analysis, Oxford University Press
(1998).
8. Joseph B. Lambert; Shurvell; Lightner; Cooks, Organic Structural Spectroscopy,
Prentice-Hall (1998).
9. Jackmann and Sternhell S, NMR Spectroscopy of Organic compounds.
10. R. K. Harris, Nuclear magnetic Resonance, Pitman, London, 1983.
11. D. N. Sathyanarayana,Introduction to Magnetic Resonance Spectroscopy ESR, NMR,
NQR, I K International Publishing House Pvt. Ltd 2009.
12. Edmond de Hoffmann; Vincent Stroobant, Mass Spectrometry: Principles and
Applications, 3rd Edition.
73
CHEM 343: ELECTROCHEMICAL TECHNIQUES SENSORS AND
ENVIRONMENTAL MANAGEMENT
Unit-I: [15L]
1. Voltammetry and polarography:
Necessity and development of new voltammetric techniques and their
comparison with classical DC polarography, Current sampled (TAST)
polarography, Pulse (normal, differential and differential double pulse)
Polarography, AC and square wave, linear sweep voltammetry and cyclic
voltammetry, criteria of reversibility of electrochemical reactions, Quasi
reversible and irreversible processes,
Unit-II: [15L]
2..1 Stripping voltammetry, adsorptive stripping voltammetry, voltammetry with
ultra micro electrodes chemically modified electrodes. Applications of
electrochemical methods in organic synthesis.
2.2 Chronotechniques:
Chronopotentiometry and Chronoamperometry, Chronocoulometry
2.3 Quartz crystal microbalance:
Principles, methodology and applications.
Unit-III:
Chemical Sensors: [15L]
3.1 Introduction to principles of chemical sensing:
Signal transduction, Physico-chemical and biological transducers, Sensor
types and technologies. Screen-printed electrodes
3.2 Physico-chemical sensors and transducers:
Thermal sensors, Electrochemical sensors (amperometric, potentiometric,
conductimetric), Semiconductor transducers (ISFET), Optical transducers
(absorption, fluorescence, bio/chemiluminescence, SPR), Piezoelectric and
acousticwave transducers, An Overview of Performance and Applications.
3.3 Biochemical sensors
Enzymes, Oligonucleotides and Nucleic Acids, Lipids (Langmuir-Blodgett
bilayers, Phospholipids, Liposomes), Membrane receptors and transporters,
Immunoreceptors.
3.4 Applications:
Environmental monitoring, Technological process control, Food quality
control, Clinical chemistry, Test-strips for glucose monitoring, Screen
printed electrodes, Implantable sensors for long-term monitoring, Forensic
science.
Unit-IV:
Environmental Management: [15L]
4.1 Solid waste management:
Objectives of solid waste management, Hazardous wastes:
Bio-medical, radioactive and E-waste, concept of recycle, reuse and
recovery, disposal and management of solid industrial waste, Bioremediation
and phytoremediation.
74
4.2 Environmental impact assessment:
Concept, process and evaluation methodology for the same.
Reference Books:
1.Modern Polarographic Methods in Analytical Chemistry, A. M. Bond, Marcel Dekker,
New York (1980).
2.Electrochemical Methods, A. J. Bard and L. R. Faulkner, John Wiley, New
York (1980).
3.Electrochemistry for Chemists, 2nd Ed., Donald T. Sawyer, A. Sobkowiak and J.
L. Roberts, Jr., John Wiley, New York (1994).
4.Cyclic Voltammetry and the frontiers of Electrochemistry, M. Noel and K. I. Vasu,
IBH, New Delhi. (1990).
5.Technique and Mechanism in Electrochemistry, P. A. Christensen and A. Hamnett,
Blackie Academic and Professional (1994).
6.Electroanalytical Chemistry, Ed. A.J. Bard, Marcel Dekker, New York, A Series of
volumes.
7.Electroanalytical Chemistry, J.J. Lingane, 2nd Ed., Interscience, New York (1958).
8.Principles of Instrumental Analysis, D.A. Skoog, F.J. Holler, and J.A. Nieman 5th
Edition (1998).
9.Jiri Janata, Principles of Chemical Sensors, Plenum Press, 1990
10. Principles of Chemical and Biological Sensors, D. Diamond Editor, John Wiley&
Sons, 2000.
11. Chemical Sensors and Biosensors, Brian Eggins, John Willey & Sons, 2002.
12. Sensors, Nanoscience, Biomedical Engineering, and Instruments. Richard Dorf Editor,
CRC Taylor & Francis, 2006
13. Optical Biosensors. Present & Future. Editors: F. Ligler, C. Rowe Taitt, Elsevier,
2002.
14. Introduction to Bioanalytical Sensors, Alice Cunningham, John Wiley& Sons, 1998.
15. Chemical Sensors and Biosensors for Medical and Biological Applications, Ursula
Spichiger-Keller,Wiley-VCH, 1998.
16. Environmental Chemistry, A.K. De, 2nd Ed., Wiley, 1989.
17. Fundamentals of Environmental Chemistry. S.E. Manahan, 3rd Ed., CRC Press, 2009.
18. Solid and Hazardous Waste Management. S.C. Bhatia, Atlantic Publishers &
Distributers (P) Ltd. New Delhi, 2007.
19. Environmental pollution and Control. J. J. Peirce, R. F. Weiner and P. A. Vesilind,
4thEdn. Butterworth-Heinemann, USA, 1998.
20. E-waste: implications, regulations, and management in India and current global best
practices. Rakesh Johri, TERI Press, New Delhi, 2009.
CHEM 346: ANALYTICAL CHEMISTRY PRACTICAL III

Organic, medicinal, food, detergents, biochemical, electroanalytical:
Organic analysis:
1. Determination of Sulphur compounds eg. Methyleneblue, crystal violet.
Analysis of medicinal:
2. Complete pharmacopoeial assay of acetyl salicylic acid. (I.P.).
75
3. Sorensen formol titrations eg. Glycine.
4. Nonaqueous titrations eg. glycine, sodium benzoate, pyridoxine HCl, mebendazole.

diazepam tablets, sulphamethoxazole, etc.
Estimation of organic compounds in drug formulations:
5. Benzoic acid and salicylic acid, Aspirin and caffeine, Dextrose and saline injection,
Chloramphenicol palmitate suspension, Paracetamol.
Analysis of food products:
6. Iodine value of oils and fats.
7. Fe, Ca, and P in milk powder, Proteins in milk and wheat flour, Lactose in milk by
Cole‟s ferricyanide method.
8. Analysis of alcoholic beverages.
Analysis of detergents:
9. Moisture content, Oxygen releasing compounds, Alkalinity, Tripolyphosphate,

Active detergent material (anionic, cationic, non –ionic, ampheteric detergents).
Biochemical analysis: Determination of the following in serum/blood.
10. Uric acid, Sugar, Cholesterol.
11. Analysis of Arsenic from hair by hydride generation technique.
Electroanalytical methods:
12. Determination of mixture of acids eg. HCl and phosphoric acid potentiometrically
using glass electrode.
13. Determination of organic aminesby potentiometric titration in glacial acetic acid.
1. Determination of reversibility of a redox system and area of an electrode by cyclic

voltammetry.
CHEM 347: ANALYTICAL CHEMISTRY PRACTICAL IV

Minerals, ores, alloy, spectrometry, water, soil, fertilizer and column
Chromatography:
Ores &Alloy:
1. Bauxite:
Al (gravimeric), Fe (volumetric), Ti (colorimetric).
76
2. Ilmenite.
Ti (gravimetric/volumetric), Fe (colorimetric).
3. Steels and stainless steels.
Ni (homogeneous precipitation), Cr (volumetric), Mn (spectrophotometric).
Spectrophotometry & AAS:
4. Determination of copper and bismuth of a mixture using EDTA

spectrophotometrically.
5. Determination of copper by extractive photometry using diethyldithiocarbamate.
6. Determination of tin and zinc in canned food by Atomic Absorption Spectroscopy.
7. Determination of Water Quality Parameters:
Soil & fertilizer Analysis:
8. NPK ratio, Determination of micronutrients, Cation exchange capacity.
Column chromatography:
9. Separation of cadmium and zinc on an anion exchanger.
10. Analysis of mixture of alcohols by GC (ethanol, n- propanol, n-butanol, n-

pentanol and t-butanol.).
11. Separation and estimation of a mixture of acetophnone, benzene and toluene by

HPLC using C18 column and acetonitrile + water (60:40) mobile
phase.Determination of number of theoretical plates.
ELECTIVE COURSES
CHEM 344: EC-I -SPECIAL TOPICS IN ANALYTICAL CHEMISTRY-I

Unit-I ANALYTICAL BIOCHEMSITRY [15L]
1.1 Body fluids:
Composition of body fluids and detection of abnormal level of certain
constituents leading to diagnosis of diseases.
Physiological and nutritional significances of water and fat soluble
vitamins and minerals.
Analyses for constituents of physiological fluids, viz., urine & blood.
Analytical techniques for vitamins
1.2 Immunological methods:
General Processes of immune response, Antigen-antibody reactions,
77
Precipitation reactions, radio, enzyme, and fluoro-immuno assays,
affinity chromatography.
1.3 Human nutrition:
Biological values and estimation of enzymes, carbohydrates, essential
amino acids, proteins, and lipids.
Unit-II:CLINICAL CHEMISTRY: (APPLICATIONS OF [15L]
BIOANALYTICAL APPROACH TO MEDICINES)
2.1 Biologics:
Brief introduction of drugs to biologics (pathway)
2.2 Nuclear medicines:
Role of radiopharmaceuticals in vivo metabolism of
radiopharmaceuticals. Uses and adverse side effects.
Principles of various instruments used for diagnosis of various diseases
eg. MRI, CT scan, etc.
Radiopharmaceuticals used in disease treatment (doses regulation) eg.
For chemotherapy of cancer.
2.3 Nanomedicines:
Importance of nanomedicines: Analytical techniques for quantification
of nanoparticles uptake by cells (transmission electron microscopy and
flow cytometry).
Bioequivalence of nanomedicines.
Unit-IIIANALYTICAL CHEMISTRY IN FORNSIC SCIENCE
General idea [15L]
3.1 Biological: Analysis of biological stains and materials including blood,
semen and saliva (qualitative and quantitative).
3.2 Analytical toxicology: isolation, identification and determination of the
following:
Narcotics: Heroin, morphine and cocaine.
Stimulants: amphetamines, cocaine and caffeine.
Depressants: benzodiazepines, Barbiturates and mandrax.
Hallucinogens: LSD and Cannabis.
Metabolites of Drugs in blood and urine of addicts.
Viscera, stomach wash, vomit, and post-mortem blood, for poisons like
cyanide, arsenic, mercury, insecticides, and pesticides.
Unit-IVMEMBRANE SCIENCE & TECHNOLOGY [15]
4.1 Membranes for saline water treatment
4.2 Ceramic membrane
4.3 Recovery of valuables from waste using liquid membrane methods
4.4 Membrane based separations in chemical and nuclear technology
78
4.5 Membrane based chemical sensors.
4.6 Track etched membrane.
Reference books:
1.West, E S & Todd, W R, Textbook of Biochemistry,Published by The Macmillan Co,
1956.
2.Parikh‟s text book of medical Jurisprudence and toxicology, C.K. Parikh, CBS
Publishers (1990).
3.Clarke‟s Isolation and identification of Drugs in Pharmaceuticals, body fluids and
post-mortem material, Clarke E.G.C., The Pharmaceutical Press, London.
4.Analytical methods in Forensic chemistry Ed. Math. Ho, Ellis Horwood (1990).
5.Methods of Forensic Science, Ed. F. Landquist, Interscience (1962).
6.High performance liquid chromatography in Forensic Chemistry. E.S. Lurie and J.W.
Wittner, Jr, Marcel Dekker N.Y. (1983).
7.Analytical Toxicology Methods Manual Ed. H. Stahr, Iowa State University Press
(1977).
8.Official Methods of Analysis of the Association of official Analytical Chemists
(AOAC), 14TH Ed. (1984).
9.Linda Fossati Wood, MaryAnn Foote, Targeted regulatory writing techniques: Clinical
documents for drugs and biologics.
10. Jeanne Yang: A Pathway to Follow-On Biologics, Hasting Science & Technology
Law Journal.
11. Gopal Subramanian, Society of Nuclear Medicine, Radiopharmaceuticals.
12. Harry F. Tibbals, Medical Nanotechnology and Nanomedicine.
CHEM 345: EC-II- SPECIAL TOPICS IN ANALYTICAL CHEMISTRY-II

Unit-I [15L]
1.1 Radiochemical methods:
Isotope dilution method and activation analysis, radiometric and radio
release methods.
Auto, X-ray and gamma radiography.
1.2 Thermal Methods:
Simultaneous thermal analysis, Evolved gas analysis: Definition,
Instrumentation, Classification of methods (Physical, Chemical and
Spectroscopic: mass spectrometry and infrared), Applications.
Unit-IIGREEN CHEMISTRY [15L]
2.1 Principles and Concepts of Green Chemistry:
Sustainable development and green chemistry, Atom economy,
examples of atom economic and atom un-economic reactions
2.2 Waste:
Production, Problems and Prevention; Sources of waste from chemical
industry, on-site waste treatment (Physical treatment and Chemical
treatment), design for degradation.
2.3 Catalysis and Green Chemistry:
Comparison of catalyst types, Heterogeneous catalysts (zeolites and
the bulk chemical industry, catalysts in fine chemicals and
79
pharmaceutical industries, catalytic converters), homogeneous
catalysts (transition metal catalysts with phosphene ligands, greener
Lewis acids, asymmetric catalysis), phase transfer catalysis,
Biocatalysis, Photocatalysis
2.4 Organic solvents:
Environmentally benign solutions: solvent free systems, supercritical
fluids, ionic liquids as catalysts and solvents.
Unit-IIICOSMETIC, SOAP & DETERGENT ANALYSIS [15L]
3.1 Cosmetic Analysis:
Introduction to cosmetics
Hair tonic: 2,5-diaminotoluene, potassium bromate, sodium perborate,
pyrogallol, resorcinol, salicylic acid, dithioglycollic acid (in
permanent wavers).
Creams and lotions: types of emulsions, chloroform soluble material,
glycerol, pH emulsion, ash analysis, non-volatile matter by IR
spectroscopy.
3.2 Soap and Detergents analysis:
Analysis of soaps and detergents: General scheme of analysis,
sampling, alcohol soluble materials, moisture and volatile matter,
active ingredient and equivalent combined SO33-.
Tests for soaps: total fatty acids, fatty anhydride combined alkali, and
anhydrous soap, Unsponified and unsaponifiable matter, Free alkali or
free acid, titer test, Iodine value, saponification value, free glycerol.
Tests for synthetic detergents: Unsulfonated or unsulfated matter,
ester SO3, Combined alcohols, total combined SO3, Alkalinity,
chlorides, silicate, phosphate, borates.
UV spectroscopic analysis of detergents: Biodegradability of
detergents, Determination of sodium alkyl benzene sulfonate,
determination of sodium toluene sulfonate, determination of sodium
xylene sulfonate, determination of germicides in soaps and detergents.
Unit-IVANALYSIS OF HERBAL BASED PRODUCTS [15L]
4.1 Herbs as a raw material:
Definition of herb, herbal medicine, herbal medicinal products, herbal
drug preparation.
Sources of herbs
Selection, identification and authentication of herbal materials, drying
and processing of herbal raw material.
4.2 Extraction of herbal materials:
Choice of solvent for extraction
Methods used for extraction and principles involved in extraction.
4.3 Standardization of herbal formulation and herbal extracts:
Standardization of herbal extract as per WHO cGMP guidelines.
Physical, chemical, spectral and toxicological standardization,
qualitative and quantitative estimations.
4.4 Various chromatographic techniques for the separation,
identification, purification and estimation.
80
Reference books:
1.Nuclear and Radiochemistry, 3rd Edition, G. Friedlander, J. W. Kennedy, E. S. Macias
and J. M. Miller, Wiley, New York, 1981.
2.Nuclear and radiochemistry, K. H. Lieser, 2nd Edition, Weinheim, Germany, Wiley
VCH, 2001.
3.Radiochemistry and Nuclear Methods of Analysis, W. D. Ehmann and D. E. Vance,
Wiley, New York 1981.
4.Thermal Methods of Analysis, P. J. haines, Blacke, London, 1995.
5.Thermal Analysis, 3rd Edition, W. W. Wendlandt, Wiley, New York, 1985
6.Paul T. Anastas, John C. Werner, Green chemistry: Theory and Practice, Oxford
7.Mike Lancaster, Green Chemistry: An Introductory Text, RSC Paperbacks. Chemistry
of Natural Products, V. K. Ahluwalia, L. S. Kumar, S. Kumar, Ane Books, India,
(2006).
8.High-Performance Thin Layer Chromatography (HPTLC), M. Shrivastav, Springer-
Verlag Berlin Heidelberg, New York, (2011).
9.Traditional and Folk Herbal Medicine, Vol. 1, Dr. V. K. Gupta, Daya Publishing
House, (2012).
10. A Selection of Prime Ayurvedic Plant drugs-Ancient Modern Concordance, S. Dev,
Anamaya Publishers, New Delhi, (2006). F.J. Welcher, Standard methods of chemical
analysis, volume 3, part-B, (Soap and Detergents).
81
SEMESTER-IV: PHYSICAL CHEMISTRY
Examination
No. of hours
Course per
Code SEMESTER
Marks Marks
CHEM Atomic structure,

group theory & 4 60 40 60 100
411
chemical bonding
CHEM Electrochemistry-II
4 60 40 60 100
412
Physical aspects of
CHEM polymer, photo-
4 60 40 60 100
413 physical & photo-
chemical processes
CHEM Intellectual Property
414 Rights & 4 60 40 60 100
OC-I Chemoinformatics
CHEM
Research
415 4 60 40 60 100
Methodology
OC-II
CHEM
Research Project 8 * 80 120 200
416

Students will have to select one of the optional courses i.e. CHEM 414 OC-I or CHEM
415 OC-II
*Practical component involves 16 hr per week of laboratory work for 15 weeks.
82
SEMESTER-IV: PHYSICAL CHEMISTRY
CHEM 411: ATOMIC STRUCTURE, GROUP THEORY & CHEMICAL BONDING
Unit-IAPPROXIMATE METHODS [15L]

Variation method (linear and non-linear), Non-degenerate first order perturbation theory,
Application to helium atom-ground state, Hückel molecular orbital method: conjugated 
systems, Dissociation energy and aromaticity, π-electron densities and bond orders, Theory of
electrocyclic reactions –Woodward‟s-Hoffmann rule, Introduction to extended Hückel
molecular orbital method
Unit-II MULTI-ELECTRONIC ATOMS & THEORY OF ANGULAR MOMENTUM

[15L]
Anti-symmetry and Pauli principle, Slater determinants, Slater type orbitals, Basis sets,
Russell-Saunders coupling, Term symbols, Hund‟s rules, Normal and anomalous Zeeman
effect, Paschen Back effect
Unit-III GROUP THEORY [15L]

Symmetry elements and symmetry operations, Symmetry point groups, Identification of point
group of molecules, Representation of groups, Matrix representation of operations,
Characters and character tables, Reducible and irreducible representations, Statement of the
Great Orthogonality theorem and its consequences, Symmetry adapted linear combination
Unit-IV DIATOMIC & POLYATOMIC MOLEUCLES [15L]

Diatomic molecules:
Born-Oppenheimer approximation, Valence bond theory of hydrogen molecule, Molecular
orbital theory of hydrogen molecule ion, Molecular orbitals of homonuclear and
heteronuclear diatomic molecules, Bond order, Term symbols.
Polyatomic molecules: Hartee-Fock SCF method and configuration interaction, Walsh

diagrams.
Reference books:
2. D. A. McQuarrie, Quantum Chemistry, Viva Books Private Limited, New Delhi, first
Indian ed., 2003.
3. R. K. Prasad, Quantum Chemistry, 3rd Ed., New Age International Publishers, 2006.
4. Ira N. Levine, Quantum Chemistry, 5th Ed., Pearson Education (Singapore) Pte. Ltd.,
5. James E. House, Fundamentals of Quantum Chemistry, Second Ed., Academic Press,
2005.
6. Robert L. Carter, Molecular Symmetry and Group Theory, John Wiley and Sons (Asia)
Pte. Ltd., 2004.
7. T. A. Littlefield and N. Thorley, Atomic and Nuclear Physics – An Introduction, Van
Nostrand, 1979.
83
1. John P. Lowe, Quantum Chemistry, 3rd ed., Academic Press, New York, 2006.
2. R. Anantharaman, Fundamentals of Quantum Chemistry, McMillan India Limited, 2001.
4. David O. Hayward, Quantum Mechanics for Chemists, Royal Society for Chemistry,
2002.
5. Jack Simons, An Introduction to Theoretical Chemistry, Cambridge University Press,
2003.
6. Victor M. S. Gil, Orbitals in Chemistry, A Modern Guide to Students, Cambridge
7. A. K. Chandra, Introduction to Quantum Chemistry, 4th Ed., Tata-McGraw-Hill, 1994.
8. S. N. Datta, Lectures on Chemical Bonding and Quantum Chemistry, Prism Books Pvt.
Ltd., 1998.
9. R. McWeeny, Coulson’s Valence, 3rd. Ed., Oxford University Press, 1979.
10. J. N. Murell, S. F. A. Kettle and J. M. Tedder, The Chemical Bond, Wiley, 1985.
11. F. A. Cotton, Chemical Applications of Group Theory, 3rd Ed., John Wiley and Sons
(Asia) Pte. Ltd., 1999.
12. D. C. Harris and M. D. Bertolucci, Symmetry and Spectroscopy, Oxford University.
CHEM 412: ELECTROCHEMISTRY-II

Principles, Instrumentation and applications of the following:
Unit I POLAROGRAPHY [15L]
Necessity and development of new voltammetric techniques and their
comparison with classical DC polarography, Current sampled (TAST)
polarography, Pulse (normal, differential and differential double pulse)
Polarography,
Unit II VOLTAMMETRY
AC and square wave, linear sweep voltammetry and cyclic voltammetry,
criteria of reversibility of electrochemical reactions, Quasi reversible and
irreversible processes, stripping voltammetry, adsorptive stripping
voltammetry, voltammetry with ultra-micro electrodes, Chemically modified
electrodes, Applications of electrochemical methods in organic synthesis.
Unit III CHRONOTECHNIQUES & SENSORS [15L]
Electrochemical sensors-potentiometric sensors, amperometric sensors and
conductivity measurement; Ion selective field effect transistors -Principle,
applications and advantages; Biosensors-Bio catalytic membrane electrodes,
enzyme based glucose biosensors; Analysis based on multilayer films-
General Principle, film structures; Disposable multilayer pIon systems-
General principle, performance and applications; Screen printed electrodes.
Quartz Crystal Microbalance: Principles and Applications.
Unit IV ELECTROPHORESIS [15L]
Zone electrophoresis, factors affecting migration rates, supporting media (gel,
paper, cellulose acetate, starch, polyacrylamide, agarose, sephedax, and thin
layers).
Techniques of electrophoresis: low and high voltage, SDS-PAGE, isoelectric
focusing; continuous and discontinuous electrophoresis, Capillary
84
electrophoresis, electro osmotic flow; Techniques of capillary electrophoresis:
zone, gel, isoelectric focusing, isotechophoresis and micellar electrokinetic
capillary chromatography, detection and applications.
Reference books:
1. D. A. Skoog, F. J. Holler, and T. A. Nieman, Principles of Instrumental Analysis,
th
5 ed., Philadelphia: Saunders College Publishing, 1998.
2. D. A. Skoog, D. M. West, F. J. Holler and S. R. Crouch, Fundamentals of
Analytical Chemistry, 8th ed., Philadelphia: Saunders College Publishing, 2004.
3. A. J. Bard and L. R. Faulkner, Electrochemical Methods, Wiley, New York, 1980.
4. A. M. Bond, Modern Polarographic Methods in Analytical Chemistry, Marcel
Dekker, New York, 1980.
5. J. J. Lingane, Electroanalytical Chemistry, 2nded.
6. A. Braithwaite and F. J. Smith, Chromatographic Methods, 5th ed., Kluwer
Academic Publisher, 1999.
7. F. W. Fifield and D. Kealey, 5th ed., Blackwell science Ltd. 2000.
8. Andrew G. Ewing, Ross A. Wallingford, and Teresa M. Olefirowicz, Analytical
Chemistry, Vol. 61 No. 4.
CHEM 413: PHYSICAL ASPECTS OF POLYMER, PHOTO-PHYSICAL & PHOTO-

CHEMICAL PROCESSES
Unit I POLYMER SCIENCE-I [15l]
Introduction:
Polymer science, Classification of Polymers, Nomenclature of
polymers, Isomerism in Polymer chains, History of Polymers,
Intermolecular forces in Polymers, Conformations in polymer chains.
Molecular weight of polymers:
Solubility, Average molecular weight values, Fractionation of
polydisperse systems, Light scattering, GPC, Collegative molecular
weights : Osmometry, End group analysis, Other techniques :
Ultracentrifugation, Mass spectrometry, Viscometry.
The Synthesis of Polymers:
Chain growth (Addition) polymerization: Mechanism, and kinetics
of free radical, cationic and anionic polymerization, Chain transfer
reactions, Mayo equation, Thermodynamic aspects of polymerization
Copolymerization:Kinetics of copolymerization, monomer reactivity
ratios, determination of monomer reactivity ratios, The Q-e scheme,
block copolymers, graft copolymers, dendtires
Unit II POLYMER SCIENCE-II [15L]
Techniques of polymerization (Phase systems in polymerisation): Bulk
polymerization, Solution polymerization, Precipitation
polymerization, Suspension polymerization, Emulsion polymerization
Step-growth polymerization (Polycondensation): Molecular weight in
a step-growth polymerization, Mechanism of polycondation, Kinetics
85
of polycondation.
Polymer reactions, degradation and additives: Polymer analog
reactions and Cross-linking reactions.
Polymer degradation and stability: Thermal degradation, Oxidative
and UV stability, Chemical and hydrolytic stability, Radiation effect
Polymer additives: Plasticizers, Stabilizers (Heat & UV), Flame
retardants, Colorants, Curing agents and other polymer additives
Polymer solutions: Solubility parameter, Solubility of crystalline and
amorphous polymers, Thermodynamics of polymer solutions, Flory-
Huggins theory of polymer solutions
Unit III PHOTOCHEMISTRY-I [15L]

Mechanism of Absorption and Emission processes:
Electric dipole transition, Einstein‟s treatment of absorption and emission
phenomena, Time-dependent Schrodinger equation, Time-dependent
perturbation theory, correlation with experimental quantities, Intensity of
electronic transitions, rules governing transition between two energy
states
Physical Properties of Electronically excited molecules:
Nature of changes on electronic excitation, Electronic, vibrational and
rotational energies, potential energy diagram, Frank-Condon principle,
Emission spectra, Environmental effect on absorption and emission
spectra, properties of excited states, excited state acidity constants, dipole
moments and redox properties. Types of transitions, fluorescence
emission, e-type and p-type delayed fluorescence, phosphorescence
emission.
Unit IV PHOTOCHEMISTRY-I [15L]
Photo-physical Kinetics:
Photokinetic scheme for determination of quantum yields, Kinetics of self
and collisional quenching and Stern- Volmer equation and deviations
from Stern Volmer equation, Concentration dependence of quenching and
excimer formation, Quenching by added substances: charge transfer
mechanism and energy transfer mechanism.
Photo-chemical reactions:
Types of photo-chemical reactions, Selection rules, Kinetics of Photo-
chemical reactions. Photochemical reactions of ketones, olefins
conjugated olefins and aromatic compounds. Woodward-Hoffman rule of
electro-cyclic reactions.
Applications of Photochemistry:
Importance of photochemistry, mutagenic effect of radiation,
photosynthesis, mechanism of vision, photo electrochemistry, prospects of
solar energy conversion and storage, organic solar cells.
Reference books:
86
1. P. Bahadur and N. V. Sastry, Principles of Polymer Science, second edition, Narosa
Publishing House, 2005.
2. C. E. Carraher, Jr., Carraher‟s Polymer Chemistry, 8th edition, CRC Press, New York,
2010.
3. Joel R. Fried, Polymer Science and Technology, Prentice-Hall of India Pvt. Ltd., 2000.
4. V. R. Gowarikar, H. V. Viswanathan and J. Sreedhar, Polymer Science. New Age
International Pvt. Ltd., New Delhi, 1990.
5. F. W. Billmeyer Jr., Text Book of Polymer Science, 3rd edition, John Wiley and Sons, 1984.
6. K.K. Rohatgi-Mukherjee, Fundamentals of Photochemistry, New Age International
Publishers, Revised Edition (2003).
7. C.H.DePuy and O.L.Chapman, Molecular reactions and photochemistry, Prentice hall of
India PVT.LTD. 1988.
Books for further reading:

1. J. M. G. Cowie, Polymers: Chemistry and Physics of Modern Materials, 2nd ed. (first
Indian Reprint 2004), Replika Press Pvt. Ltd.
2. G. S. Misra, Introductory Polymer Chemistry, New Age International (P) Limited,
Publishers, 1993.
3. L. H. Sperling, Introduction to Physical Polymer Science. 2nd Edition, John Wiley and
Sons. Inc.
4. Hans- Georg Elias, An Introduction to polymer Science, VCH 1997.
5. Charles E. Seymour, Jr., Seymour/Carraher’sPolymer Chemistry, 6th ed., Marcel Dekker,
Inc., 2003.
6. A. Ravve, Principles of Polymer Science, 2nd ed., Kluwer Academic/Plenum Publishers,
New York, 2000.
CHEM 416: RESEARCH PROJECT
87
SEMESTER-IV: INORGANIC CHEMISTRY
No. No. of Examination

of hours per Total
Course Continuous End-
Title of the Course Cred SEMEST Marks
Code Evaluation Sem
its -ER
CHEM Solid State Chemistry -
4 60 40 60 100
421 II
Organometallic
CHEM
Chemistry and 4 60 40 60 100
422
Catalysis
Instrumental Methods,
CHEM
Spectroscopy & Group 4 60 40 60 100
423
Theory
424 Rights & 4 60 40 60 100
CHEM
425 Research Methodology 4 60 40 60 100
OC-II
CHEM
426

425 OC-II
*Practical component involves 16 hr per week of laboratory work for 15 weeks
88
SEMESTER-IV: INORGANIC CHEMISTRY
CHEM 421: SOLID-STATE CHEMISTRY-II

Unit-I ELECTRICAL PROPERTIES OF SOLIDS: [15L]
(i) Ionic conductivity and solid electrolytes:
Mechanism of conduction in solid electrolytes, e.g. hopping conduction; fast ion
conductors, e.g. silver ion conductors, oxygen ion conductors, sodium ion conductors;
applications of solid electrolytes, e.g. electrochemical cells, batteries, sensors, fuel cells.
Diffusion in Solids: Fick‟s laws of diffusion, mechanism, Kirkendall effect, diffusion and
ionic conductivity.
(ii) Electrical Properties:
Band structures of metals, insulators, semi-conductors and inorganic solids; Applications
of semiconductors; Other electrical properties: Thomson, Peltier and Seebeck effects,
thermocouples and their applications, Hall effect, dielectric, ferroelectric, piezoelectric
and pyroelectric materials and their inter-relationship and applications.
Unit-IIMAGNETIC PROPERTIES OF SOLIDS: [15L]

Behaviour of substances in magnetic field, mechanism of ferromagnetic and
antiferromagnetic ordering, superexchange, Hysteresis, Hard and soft magnets, Structures
and magnetic properties of metals and alloys, transition metal oxides, spinels, garnets,
ilmenites, perovskite and magneto-plumbites, Applications in transformer cores,
information storage, magnetic bubble memory devices and as permanent magnets.
Unit-III [15L]
(a)Optical Properties of Solids:
Luminescence and phosphor materials: Configurational coordinate model, Anti-
Stokes phosphor, Lasers: Ruby laser, Neodymium laser. Absorption and emission of
radiation in semiconductor:light emitting diodes, gallium arsenide laser, blue lasers;
optical fibers.
(b)Thermal properties of solids:
Introduction, heat capacity and its temperature dependence, thermal expansion of
metals, ceramics and polymers, thermal conductivity, mechanism of heat conduction
metals, ceramics and polymers; thermal stresses.
Unit-IVADVANCES IN NANOMATERIALS [15L]
Introduction to nanotechnology:
Generalpreparative methods for various nanomaterials, functionalization of nanoparticles
for various applications (capping), generic challenges in nanomaterial synthesis.
Some important properties of nanomaterials:
Optical properties of metal and semiconductor nanoparticles, magnetic properties.
Some special nanomaterials:
Carbon nanotubes:
89
Types, synthesis using various methods, growth mechanism, electronic structure;
quantum dots: properties and applications. Aerogels: types of aerogels, properties and
applications of aerogels.
Applications of nanomaterials in electronics, energy, automobiles, sports and toys, textile,
cosmetics, medicine, space and defense. Environmental aspects of nanotechnology.
CHEM 422: ORGANOMETALLIC CHEMISTRY & CATALYSIS

Unit-IORGANOMETALLIC CHEMISTRY OF p-BLOCK ELEMENTS[15L]
Organometallics of boron group elements (organoboron, organoaluminium,
gallium,indium and thallium organyls). Organometallics of carbon group elements
(organogermanium, organotin and organolead compounds).Organometallics of nitrogen
group elements (organometallics of arsenic, antimony and bismuth). Organometallics of
oxygen group elements (organoselenium and organotellurium).
Unit-II [15L]
(a) Organometallic chemistry of f-block elements:
Neutral binary σ-organyls, agostic interactions, carbene complexes, alkynyl compounds,
5, 6, 7 and8 compounds.
(b) Metal-metal bonding and metal atom clusters:
Electron count and structures of clusters, synthesis, reactions, isolobal analogy and
structures, Wade‟s rule (applications to boranes, carboranes and organometallic
compounds).
Unit-III [15L]
a) Introduction to catalysis andorganometallics as catalysts in organic
reactionsinvolving hydrogen:
hydrogenation, asymmetric hydrogenation,hydrosilyation, hydroboration and
hydroamination reactions, disilylation and diboration reactions.
(b) Organometallics as catalysts in organic reactionsinvolving carbon monoxide:
Hydroformylation, carbonylation, Water-Gas shift reaction, Fischer-tropsch, alcohol
carbonylation, Wacker process, aminocarbonylation reactions.
Unit-IV [15L]
(a) Organometallics as catalysts in organic reactionsinvolving unsaturated
hydrocarbons:
Olefin oligomerization (SHOP process, ethene trimerization, propene dimerization and
cyclotrimerization of butadiene), alkene isomerization and alkene/alkyne metathesis
(alkene metathesis, alkyne metathesis, alkene-alkyne metathesis).
(b) Organometallics in C-X bond formations reactions:
C-C, C-S, C-N bond formation reactions, Heck, Suzuki, Sonogasira, Stille reactions and
Reppe Synthesis.
CHEM 423: INSTRUMENTAL METHODS, SPECTROSCOPY & GROUP THEORY

Unit-I [15L]
Infrared spectroscopy:
Introduction to basic principles, instrumentation, factors affecting the character of
vibrations, IR absorption bands of metal - donor atom, effect of complex formations on
90
the IR spectrum of ligands like CO32-, SO42-, NO3-, NO2-, NH3, CN1-, CO, olefins (C=C)
and CH3COO1-. Determination of structures of inorganic molecules.
Raman spectroscopy:
Introduction to basic principles andinstrumentation.Applications of Raman spectroscopy
in determination of molecular structures like diatomic molecules, triatomic molecules,
structure of complex ions in solutions, nitric acid, sulphuric acid.
Nuclear Magnetic Resonance:
Introduction to basic principles and instrumentation. Spectra of paramagnetic materials:
Contact shift, application of contact shift, lanthanide shift reagent. Use of 1H, 19F, 31P, 11B
NMR spectra in structural elucidation of inorganic compounds.
Unit-IIMICROSCOPY FOR SURFACE CHEMISTRY [15L]
Introduction to surface spectroscopy, microscopy, problems of surface analysis,
distinction of surface species, sputter etching and depth profile and chemical
imaging.Principle, instrumentation and applications offollowing techniques: ion
scattering spectra (ISS), secondary ion mass spectroscopy (SIMS), Auger emission
spectroscopy (AES), ESCA, scanning electron microscopy (SEM), atomic force
microscopy (AFM) and transmission electron microscopy (TEM).
Unit-IIITHERMAL& OPTICAL METHODS OF ANALYSIS [15L]
(a) Introduction to principles and instrumentation of thermoanalytical techniques TGA,
DTA, DSC, Applications of thermal techniques in materials science and industry,
Determination of thermodynamic parameters for the reaction employing thermoanalytical
measurements.
(b) Circular dichroism (CD) and optical rotatory dispersion (ORD):
Introduction, principle, instrumentation and applications
Unit-IVAPPLICATIONS OF GROUP THEORY[15L]
Introduction to of basic concepts of symmetry, Matrix representation of symmetry
operations, reducible and irreducible representations, The great orthogonality theorem,
Construction of character tables for point groups C2v, C3v and D2h, Mulliken‟s notations
for irreducible representations, structure of character tables, determination of symmetry
species for translations and rotations, reduction of reducible representations using
reduction formula.
Application of group theory to infrared and Raman spectroscopy, Symmetry adapted
linear combinations, symmetry aspects of MO theory, sigma- and pi-bonding in AB4
(tetrahedral and square planar), AB5 (trigonal bipyramidal) and AB6 (octahedral)
molecule.
91
Reference books:
CHEM 421:
Unit-I:
1.A. R. West, Solid state chemistry and its chemical applications, John Wiley & Sons,
(1984).
3.R. C. Ropp Warren, Solid State Chemistry, Elsevier Science B.V. (2003).
Unit-II:
(1984).
Unit-II:
(1984).
2.W. D. Callister, Jr., (adapted by R. Balasubramaniam), Callister’s Materials science and
engineering, Wiley-India (2010).
Unit-IV:
1.Sulabha K. Kulkarni, Nanotechnology: Principles and practices, Capital publishing
company (2007)
CHEM 422:
Unit-I-IV:
1.Jahn Hartwig, Organotransition chemistry-From bonding to catalysis, University science
books, California (2010).
2.Christoph Elschenbroich, Organometallics, 3rd edition, Wiley-VCH (2005).
3.R. C. Mehrotra and A. Singh, Organometallic chemistry- A unified approach, 2nd edition,
New Age International (P) Ltd. (2000).
4.R. H. Crabtree, The organometallic chemistry of the transition metals, 5th edition, John
Wiley & Sons (2009).
(1999).
6.Gary O. Spessard and Gary L. Miessler, Organometallic Chemistry,3rdedn., Oxford
University Press (2015).
92
CHEM 423:
Unit-I:
1.R. S. Drago, Physical methods for Chemists, 2nd edition, Saunders College publishing
(1992).
2.R. S. Drago, Physical methods in Inorganic chemistry, Affiliated East-West Press Pvt. Ltd;
New Delhi
3.Fmiza Hammer, Inorganic spectroscopy and related topics, Sarup & Sons (2008).
4.D. N. Sathyanarayana, Introduction to magnetic resonance spectroscopy ESR, NMR, NQR,
I. K. Intenational publishing house pvt. Ltd. (2009).
5.K. Burger, Coordination chemistry: Experimental methods, London Butterworths, (1973).
6.C. E. Housecroft and A. G. Sharpe, Inorganic Chemistry, Pearson Education Ltd. 2nd
Edition (2005).
Unit-II:
1.D. A. Skoog and F. J. Holler and T. A. Nieman, Principles of instrumental analysis, 5th ed.,
Harcourt Asia PTE Ltd. (1998).
2.R. A. Scott and C. M. Lukehart, Applications of physical methods to inorganic and
3.Sulabha K. Kulkarni, Nanotechnology: Principles and practices, Capital publishing
company (2007).
Unit-III:
1.W. W. Wendlandt, Thermal analysis, Interscience (1985).
2.P. D. Garn, Thermoanalytical methods of investigation, Academic press, N. Y. (1963).
3.A. Blazek, Thermal analysis, Van Norstrand Reinhold Co., London (1973).
4.T. Daniel, Thermal analysis, Kogan page Ltd., London (1973).
5.C. J. Keattch and D. Dollimore, An introduction to thermal analysis, Heyden, London
(1975).
6.M. D. Judd and M. I. Pope, Differential thermal analysis, Heydon, London (1977).
7.G. W. H. Hohne, W. F. Hemminger and H. Flammerscheim, Differential scanning
calorimetry-An introduction for practioners, Springer-verlag, Berlin (1996).
8.K. Burger, Coordination chemistry: Experimental methods, London Butterworths, (1973).
9.G. W. H. Hohne, W. F. Hemminger and H. Flammerscheim, Differential scanning
calorimetry-An introduction for practioners, Springer-verlag, Berlin Heidelberg (2003).
10.R. A. Scott and C. M. Lukehart, Applications of physical methods to inorganic and
11.D. A. Skoog and F. J. Holler and S. R. Crouch, Instrumental analysis, 5th ed., Harcourt
Asia PTE Ltd. (1998).
Unit-IV:
1.Gary Wulfsberg, Inorganic chemistry, Viva Books Pvt. Ltd., (2002).
(1999).
93
4.R. L. Carter, Molecular symmetry and group theory, John Wiley & Sons, New York,
(1998).
5.S. F. A. Kettle, Symmetry and structure-Readable Group Theory for Chemists, 3rd Ed., John
Wiley & Sons, Inc. (200&0.
6.K. V. Reddy, Symmetry and Spectroscopy of molecules, New Age International (P) Ltd. 2nd
Edition, (2009).
7.A. S. Kunju and G. Krishnan, Group theory and its application in chemistry, PHL Learning
Pvt. Ltd., (2010).
8.F. A. Cotton, Chemical applications of group theory, Wiley Eastern Ltd., (1989).
94
SEMESTER-IV: ORGANIC CHEMISTRY
No. of hours
Course per
Code SEMESTER
Marks Marks
Stereochemistry,
Asymmetric Synthesis,
CHEM
Pericyclic Reactions, 4 60 40 60 100
431
Organic Electronic and
Photonic materials
CHEM Advanced Synthetic
4 60 40 60 100
432 Organic chemistry
CHEM Natural Products

4 60 40 60 100
433 Chemistry

434OC- Rights & 4 60 40 60 100
I Chemoinformatics
CHEM
435OC- Research Methodology 4 60 40 60 100
II
CHEM
436

435 OC-II
95
SEMESTER- IV: ORGANIC CHEMISTRY
CHEM 431: STEREOCHEMISTRY, ASYMMETRIC SYNTHESIS,

THEORETICALLY FASCINATING MOLECULES, ORGANIC ELECTRONIC
AND PHOTONIC MATERIALS
Unit-ISTEREOCHEMISTRY[15L]
1.1.Racemates and methods of resolution of racemates. [3L]
1.2.Chemical and Instrumental methods of determining configurations. [4L]
1.3.Conformation and reactivity in cyclic compounds with more emphasis on cyclohexane
derivatives, Reactions involving steric factors and stereoelectronic factors, Addition
reactions, substitution reactions, elimination reactions, rearrangement reactions, I-strain
concept. [4L]
1.4.Determination of enantiomer and diastereomer composition.
(a) Chiroptical methods and their limitations [Horeau effect]
(b) Methods based NMR:
Use of Chiral Derivatising Agents, CDA, Chiral Solvating Agents, CSA, and Chiral Shift
Reagents, CSR.;
(c) Chromatographic methods, use of chiral stationary phase (chiral columns) [4L]
Unit-IIASYMMETRIC SYNTHESIS[15L] Principles of asymmetric synthesis, Cram‟s
rule, Sharpless epoxidation, asymmetric dihydroxylaion, asymmetric
aminohydroxylations, asymmetric Diels-Alder reactions, chiral borane reagents,
asymmetric reductions of prochiral carbonyl compounds and olefins. Use of chiral
auxiliaries in Diastereoselective reductions. Synthesis of alpha amino acids (Corey‟s
Diastereoselective hydrogenation of cyclic hydrazones); Synthesis of L-DOPA
[Knowles‟s Mosanto process], asymmetric aldol and related reactions.
Use of Chiral BINOLs, BINAPs, and chiral oxazolines and oxazolidines in asymmetric
transformations.
Unit-IIITHEORETICALLY FASCINATING MOLEUCLES[15L] 3.1.Structures, synthesis
and properties of cyclophanes, calixarenes, C-60, rotaxanes [5L]
3.2.Design, operating photophysical principles, synthesis of selected chemo-and fluorescence
based metal ion sensors derived from crown ethers and macrocyclic systems, and chemo-
and fluorophore chelators. [8L]
3.3.The Host Guest binding phenomena:
Assessment by UV/VIS or Flourescence methods; NMR methods. The Benesi-Hildebrand
Equation, Stern Volmer relationships [2L]
Unit-IVORGANIC, ELCTERONIC & PHOTONIC MOLECULES[15L]
Organic nonlinear chromophores, Conducting polymers, Dye sensitized organic
photovoltaic materials, Organic Magnetic materials, Organic light emitting diodes.
General examples of organic conjugated chromophores and polymers, synthesis and
various applications.
96
CHEM 432: ADVANCED SYNTHETIC ORGANIC CHEMISTRY
Unit-IDOMINO REACTION & CLICK CHEMISTRY[15L]
1.1.Multi-component reactions: i) Strecker reaction ii) Hantzsch dihydropyridine synthesis
iii) Biginelli condensation iv) Passerni 3- component condensation v) Ugi 4- component
condensation iv) Domino Knoevenagel-hetero-Diels-Alder reaction.
1.2.Domino Reactions/Tandem Reaction/Cascade Reactions: Definition and Classification
Cascade processes: concept, examples of cationic, anionic and radical initiated cascade
reactions.
1.3.Click Chemistry reactions
Unit-IIPOLYMER SUPPORTED REAGENTS & ELECTROORGANIC
SYNTHESIS[15L]
2.1.Polymer supported reagents for acid base catalysis,
2.3.Introduction: Electrode potential, cell parameters, electrolyte, working electrode, choice
of solvents, supporting electrolytes.
2.4.Cathodic reductions: alkyl halides, aldehydes/ketones, nitro compounds, olefin, arenes,
Electrodimerizations.
2.5.Anodic oxidations,: Kolbe type reactions, oxidation of arylalkanes .
Unit-IIINON-CLASSICAL METHODS OF ORGANIC SYNTHESIS[15L]
Principles and applications of the following:
3.1.1) Phase transfer catalysis, crown ethers and cryptands, concepts, synthesis and
applications 2) Micelles, structures, properties and reactions 3) Ionic liquids 4)
cyclodextrin, structure and functions 5) ultrasound in organic synthesis 6) Zeolites,
structures, properties and catalysis and 7) Organocatalysis 7) Microwave in organic
synthesis 8) Solid phase synthesis
Unit-IVDESIGNING ORGANIC SYNTHESIS[15L]
4.1.Umpolung:
Concept of umpolung, generation of acyl anion equivalent-1,3-
dithiane from carbonyl compounds, use of methylthio-methylsulfoxide, via
cyanide ion and cyanohydrin ethers, nitro compounds and metallated vinyl ethers
4.2.Methodology in organic synthesis:
Functional group interconversions, general methods of 4 -7 membered ring formation,
Disconnection approach and Retrosynthetic analysis, ideas of synthones and retrones,
Examples of acyclic saturated and unsaturated systems, monocyclic and bicyclic
compounds.
4.3.Target oriented and methods oriented synthesis: Strategies and tactics.
4.4.Protection-deprotection of functional groups:
carbonyl, hydroxyl, amino, carboxyl, with examples illustrating the applications of each.
97
CHEM 433: NATURAL PRODUCTS CHEMISTRY
Unit-INATURAL PRODUCTS CHEMISTRY-I[15L]
1.1. Steroids:
Occurrence,structures, classification biological role, important structural and
stereochemical features of the following types of steroids- Estrogens, gestrogens,
androgens, corticosteroids, sterols, bile acids, calciferol, sapogenins and steroidal
alkaloids. [5L]
1.2. Synthesis of 16-DPA from cholesterol and plant sapogenin. [3L]
1.3. Synthesis of commercially important steroids from 16-DPA.[4L]
1.4. Synthesis of cinerolone, Jasmolone,allethrolone,pyrethrolone,exaltone and muscone.
[3L]
Unit-IINATURAL PRODUCTS CHEMISTRY-II[15L]
2.1.Insect pheromones:
Structural features and importance .Synthesis of bombycol, gossyplure, disparlure,
brevicomin and grandisol [5L]
2.2.Insect growth regulators:
General idea,constitution of JH, structures of JH2 and JH3 [2L]
2.3.Plant growth regulators:
Structural features and applications of aryl acetic acids, gibberelic acids, brassinolides and
triacontanol, Synthesis of triacontanol. [2L]
2.4.Antibiotics:
Classification on the basis of activity and structure determination of penicillin-G,
Cephalosporin-C and terramycin, Synthesis of penicillin-G,phenoxymethyl penicillin
and Semi-synthetic cephalosporins. [6L]
Unit-IIINATURAL PRODUCTS CHEMISTRY-III[15L]
3.1.Carbohydrates
3.2.Types of naturally occurring sugars:
Deoxy sugars,amino sugars, branched sugars. Structure determination of lactose, inositol
and amino sugars, Constitution and applications of chitin.[6L]
3.3.Natural pigments: [4L]
General structural features, occurrence, isolation,biological importance and applications
of–carotenoids,anthocyanins,flavones,xanthones,quinones,pterins and porphyrins,
Structure determination and synthesis of β-carotene and ubiquinone.
3.4.Prostaglandins:[3L]
Classification, General structure and biological importance.
Structure determination and synthesis of PGE1 and PGF1α
3.5.Lipids:[2L]
Structure and role of carbolipids,phospholipids and sphingolipids.
Unit-IVNATURAL PRODUCTS CHEMISTRY-IV[15L]
4.1.Vitamins: [5L]
Classification, sources and biological importance, Synthesis of B1,B2,B6,D,E, K and
compounds with vitamin-K activity.
98
4.2.Multi-step synthesis of natural products: [10L]
Synthesis of the following natural products with special reference to reagents used,
stereochemistry and functional group transformations-Reserpine,Longifoline,
Griseofulvin, Estrone, β- Vetivone, 4-Demethoxy daunomycin, caryophyllin, etc.
99
SEMESTER-IV: ANALYTICAL CHEMISTRY
No. of hours
No. of per Total
Course Title of the Continuous End-
Credits SEMESTER Marks
Code Course Evaluation Sem
Quality in
Analytical
CHEM
Chemistry and 4 60 40 60 100
441
Inorganic
Analysis
Advanced
CHEM Instrumental
4 60 40 60 100
442 Techniques and
Nanotechnology
Analysis Of Ores,
CHEM
Food, Agro 4 60 40 60 100
443
/Agriculture
CHEM Intellectual
444 Property Rights & 4 60 40 60 100
CHEM
Research
445 4 60 40 60 100
Methodology
OC-II
CHEM
446

445 OC-II
100
SEMESTER-IV: ANALYTICAL CHEMISTRY
CHEM 441: QUALITY IN ANALYTICAL CHEMISTRY AND PHARMACEUTICAL

ANALYSIS
Unit-IQUALITY IN ANALYTICAL CHEMISTRY [15L]
1.1 The need for reliable results:
Social and economic impact of wrong analysis, concept of quality, customer
requirement, purpose of analysis.
1.2 Principle of quality assurance quality control:
Quality management system, quality assurance and quality control, different
standards and their main features, best practice.
1.3 Sampling:
Definition, types of samples, sampling plan, sub-sampling, sample
registration and storage, acceptance sampling- inspection by attributes.
1.4 Preparation for analysis:
Method selection, Sources of methods, Factors to consider in choosing a
method, performance criteria for methods to determine analytes by selected
techniques, reasons for incorrect analytical results, method validation.
1.5 Making Measurements:
Good laboratory practice, calibration of measurement, chemical standards and
reference materials, quality control, environment, equipment, chemicals,
consumables, maintenance and calibration of equipments.
Unit-II [15L]
2.1 Data treatment:
Control charts, measurement uncertainty: Definition and evaluation of
uncertainty; putting uncertainty to use.
2.2 Documentation and its management:
Quality manual, record management and reporting results.
2.3 Managing quality:
Management system, Standards available for laboratories, audit, review,
responsibilities of laboratory staff for quality.
2.4 Signals and Noise:
Signal to noise ratio, sources of noise in instrumental analysis, signal to noise
enhancement, hardware devices and software methods for noise reduction.
Unit-IIIPHARMACEUTICAL ANALYSIS-I [15L]
3.1 General idea regarding pharmaceutical industry, definition and
classification of drugs, introduction to pharmaceutical formulations,
classification of dosage forms.
3.2 Sources of impurities in pharmaceutical chemicals and raw materials.
3.3 Standardization of finished products and their characteristics, official
methods of control, use of pharmacopoeia.
3.4 Analysis of compounds based on functional groups (eg. Aspirin,
paracetamol, ascorbic acid, vitamin-A), classical and instrumental
methods of drug analysis, proximate assays, assays of enzyme
101
containing substances, biological and microbiological assays and tests.
Unit-IVPHARMACEUTICAL ANALYSIS-II [15L]
4.1 Limit tests, solubility tests, disintegration tests, stability studies, impurity
profile of drugs, bioequivalence and bioavailability studies.
4.2 Pharmaceutical legislation: Introduction to drug acts, drug rules (schedules),
FDA and ISO standards, ISO 9000 and its requirements, introduction to
GMP.
4.3 Introduction to drug development.
Reference books:
1.Quality assurance in Analytical Chemistry, Elizabeth Prichard and Vicki Barwick,
LGC, Teddington, UK, 2007.
2.Quality Assurance in Analytical Chemistry W. Funk, V. Dammann, G.
Donnevert VCH Weinheim (1995).
3.Principles of Instrumental Analysis, D.A. Skoog, F.J. Holler, and J.A. Nieman 5th
Edition (1998).
4.Good Laboratory practice, Eds. W.Y. Garner, M.S. Barge and J.P. Ussary, ACS
Professional Refernce Book (1992).
5.Quantitative Organic Analysis Via functional groups, 3rd Ed. S. Sigia. John Wiley, N.Y.
(1972).
6.Pharmaceutical Drug Analysis (Methodology-Theory-Instrumentation Pharmaceutical
assays-Cognate Assays), AshutoshKar, New Age Int. Pvt. Ltd. New Delhi (2010).
7.Indian Pharmacopeia 2010, Vol. I, II, III and Addendum 2012, 6th Ed. The Indian
Pharmacopoeia Commission, Ghaziabad, 2010.
8.British Pharmacopeia.
9.Pharmaceutical Analysis, T. Higuchi and E. Brochmann- Hanssen, Interscience (1961).
10. The quantitative analysis of drugs, D.C. Garratt, Chapman and Hall (1964).
11. Pharmaceutical Analysis, A.H. Beckett and J.B. Stenlake, Chapman and Hall.
12. Methods of Drug Analysis, B.F. Granbowshi, Lea and Feniger.
13. Analysis of Drugs and Chemicals, N. Evers, W. Smith and C. Grifin.
14. Hawk‟s Physiological Chemistry, Mc Graw Hill.
CHEM 442: ADVANCED INSTRUMENTAL TECHNIQUES AND

NANOTECHNOLOGY
Unit-I [15L]
Principles, instrumentation and applications of following:
1.1 Electron spectroscopy: AUGER & UPS.
1.2 Electron microprobe method.
1.3 Reflectance spectroscopy.
Unit-II [15L]
Principles, instrumentation and applications of following:
2.1 Electron microscopy:
Scanning electron microscopy, Scanning probe microscopes: The
Scanning Tunneling Microscope, Atomic force Microscope.
2.2 Chemiluminescence method.
102
2.3 Photoacoustic spectroscopy.
2.4 Polarimetry: ORD, CD.
Unit-IIIHYPHENATED TECHNIQUES [15L]
3.1 Introduction, need for hyphenation, possible hyphenation, Interfacing
devices and applications of the following: GC-MS, GC-IR, MS-MS,
HPLC-MS, ICP-MS, Spectroelectrochemistry and radio-
chromatography.
Unit-IVNANOTECHNOLOGY: ADVANCES IN [15L]

NANOMATERIALS
4.1 Types of nanomaterials, Classification, General preparative methods for
various nanomaterials.
4.2 Some important properties on nanomaterials: optical, magnetic
properties, Structural and chemical properties.
4.3 Some special nanomaterials: Carbon nanotubes and quantum dots,
Preparation and applications.
4.4 Applications of nanomaterials in electronics, energy, automobiles, sports
and toys, textile, cosmetics, medicine, space and defense.
4.5 Analytical techniques for characterization of nanomaterials.
Reference Books:
1.Hofmann, Siegfried, Auger- and X-Ray Photoelectron Spectroscopy in Materials
Science Springer-Verlag Berlin Heidelberg.
2.S. J. B. Reed, I. M. Romanenko, D. S. Woolum, P. Trocellier, Microprobe Analysis.
3.Kuo, John, Electron Microscopy: Methods and Protocols, Humana Press.
4.Gustav Kortüm,Reflectance Spectroscopy: Principles, Methods, Springer; Softcover
reprint of the original 1st ed. 1969 edition (January 1, 1969).
5.John W. Birks Chemiluminescence and Photochemical Reaction Detection in
Chromatography,Wiley-VCH; (July 26, 1989)
6.Lihong V. Wang, Photoacoustic Imaging and Spectroscopy, CRC press.
7.Douglas A. Skoog; F. James Holler; Stanley R. Crouch; Principles of Instrumental
Analysis6th Edition.
8.Handbook of GC/MS Fundamentals and Applications, H. J. Hubschmann, Wienheim,
Germany, Wiley VCH, 2001
9.Modern practice of Gas Chromatography, R. L. Grab and E. F.Berry, 4th Edition, Wiley
Interscience, New York, 2004.
10. LC/MS: A Practical User Guide, W. C. McMaster, Hooken, Wiley, New Jersey, 2005.
11. Technologies and Applications of Tandem Mass Spectrometry, K. L. Busch, G. L.
Glish and S. A. McLuckey, New York, VCH, 1998.
12. Inductively coupled Mass Spectrometry, A. Montaser (Ed), Wiley VCH, Chinchester,
1998, New York.
13. Nanotechnology: Principles and Practices, J. K. Kulkarni, Capital Publishing Co.,
2007
103
CHEM 443: ANALYSIS OF ORES, FOOD, AGRO /AGRICULTURE
Unit I: Analysis of Minerals, Ores and alloys [15L]
1.1 Analytical treatment of minerals and ores: Sampling, analytical treatment,
dissolution of ores. Biomining.
1.2 Analyses of ores: bauxite and monazite.
1.3 Analysis of alloys: steel and stainless steel and copper based alloys.
Unit II: Soil and Fertiliser Analysis [15L]
2.1 Soil health card scheme. Sampling and preparation of soil samples for
analysis, solid texture estimation. pH, electrical conductance, organic
carbon, CaCO3 (free lime), cation exchange capacity, gypsum
requirements, micro and macro nutrients in soil. Soil miro-organisms
and their functions.
2.2 Different types of synthetic fertilizers and introduction to organic fertilizers
and their analysis and interaction with different components of soil.
Unit III: Food Quality Concepts [15L]
3.1 General idea regarding moisture content, ash, fibre, proteins, carbohydrates, lipids
and fats in food analysis.
3.2 Food standards – their importance and limitations. Food preservatives,
adulterants and contaminants.
3.3 Analysis-
Additives: flavours and colour.
3.4 Contaminant: heavy metals.
Unit IV: Food Analysis & Pesticide Analysis [15L])
4.1 Processing and quality control requirements of milk and milk products
(butter, cheese, ice cream), carbonated and alcoholic beverages.
4.2 Analysis of dairy products, oils, fruits and vegetables.
4.3 Pesticide Analysis-
Pesticide formulation– Application test.
4.4 Degradation of different insecticides, fungicides and weedicides in soil.
4.5 Pesticide analysis in water, beverages, food products and soil by
GC/HPLC/GC-MS.
Texts/ references:
1. Standard methods of Chemical Analysis, Vol. 2, (Part A& B), 5th ed, F. J. Welcher,
Von Nostrand & Robert E. Krieger Publishing Co. New York, (1975).
2. Quantitative Organic Analysis, Part III, 2nd Ed., A. I. Vogel, CBS, (1987).
3. Chemical Analysis of Food and Food Products, H. B. Jacob, Van Nostrand Reinhold,
(1958).
4. Association of Official Analytical Chemists.

104
OPTIONAL COURSES
OPTIONAL PAPER-I
CHEM 414-OC-I / CHEM 424- OC-I/ CHEM 434- OC-I / CHEM 444-OC-I
INTELLECTUAL PROPERTY RIGHTS & CHEMOINFORMATICS
Unit-I [15L]
Introduction to Intellectual Property: [2L]
Histroical Perspective, Different types of IP, Importance of protecting IP.
Patents: [5L]
Historical Perspective, Basic and associated right, WIPO, PCT system, Traditional
Knowledge, Patents and Health care-balancing promoting innovation with public health,
Software patents and their importance for India.
Industrial Designs: [2L]
Definition, How to obtain, features, International design registration.
Layout design of integrated circuits: [2L]
Circuit boards, Integrated Chips Importance for electronic industry.
Copyrights: [2L]
Introduction, How to obtain, Differences from Patents.
Trade Marks: [2L]
Introduction, How to obtain, Different types of marks-Collective marks, certification marks,
service marks, Trade names, etc.
Unit-II [15L]
Geographical Indications: [2L]
Definition, rules for registration, prevention of illegeal exploitation, importance to India.
Trade Secrets: [2L]
Introduction and Historical Perspectives, Scope of Protection, Risks involved and legal
aspects of Trade Secret Protection.
IP Infringement issue and enforcement: [5L]
Role of Judiciary, Role of law enforcement agencies-Police, Customs, etc.
Economic Value of Intellectual Property:
Intangible assests and their valuation, Intellectual Property in the Indian Context- Various
Laws in India Licensing an technology transfer.
Different International agreements: [6L]
(a) World Trade Organization (WTO):
(i)General Agreement on Tariffs & Trade (GATT) , Trade
Related Intellectual Property Rights (TRIPS) agreement
(ii) General Agreement on Trade related Services (GATS)
Madrid Protocol
(iii) Berne Convention
(iv) Budapest Treaty
(b)Paris Convention
WIPO and TRIPS, IPR and Plant Breders Rights, IPR and Biodiversity
Unit-III [15L]
105
Introduction to Cheminformatics: [5L]
History and evolution of cheminformatics, Use of cheminformatics, Prospects of
cheminformatics, Molecular Modeling and Structure elucidation.
Representation of molecules and chemical reactions: [5L]

Nomenclature, Different types of notations, SMILES coding, Matrix representations,
Structure of Molfiles and Sdfiles, Libraries and toolkits, Different electronic effects, Reaction
classification.
Searching chemical structures: [5L]
Full structure search, sub-structure search, basic ideas, similarity search, three dimensional
search methods, basics of computation of physical and chemical data and structure
descriptors, data visualization.
Unit-IV [15L]
Applications:
Prediction of Properties of Compound, Linear Free Energy Relations, Quantitative Structure-
Property Relations, Descriptor Analysis, Model Building, Modeling Toxicity, Structure-
Spectra correlations, Prediction of NMR, IR and Mass spectra, Computer Assisted Structure
elucidations, Computer assisted Synthesis Design, Introduction to drug design, Target
Identification and Validation, Lead Finding and Optimization, Analysis of HTS data, Virtual
Screening, Design of Combinatorial Libraries, Ligand-Based and Structure Based Drug
Design, Application of Cheminformatics in Drug Design.
Reference books:
1. Andrew R. Leach & Valerie, J. Gillet (2007) An introduction to Cheminformatcs.
Springer: The Netherlands.
2. Gasteiger, J. & Engel, T. (2003) Cheminformatics: a text-book. Wiley-VCH.
3. Gupta, S.P. QSAR and Molecular Modeling, Springer-Anamaya Pub.: New Delhi.
OPTIONAL PAPER-II
CHEM 415-OC-II / CHEM 425- OC-II / CHEM 435- OC-II / CHEM 445-OC-II
RESEARCH METHODOLOGY
Unit-ILITERATURE SURVEY[15L]
Print: [5L]
Primary, Secondary, Tertiary sources,
Journals:
Journal abbreviations, abstracts, current titles, reviews, monographs, dictionaries, text-books,
current contents, Introduction to Chemical Abstracts and Beilstein, SubjectIndex, Substance
Index, Author Index, Formula Index, and other Indices with examples.
Digital: [5L]
Web sources, E-journals, Journal access, TOC alerts, Hot articles, Citation index, Impact
factor, H-index, E-consortium, UGC infonet, E-books, Internet discussion groups and
106
commUnit-ites, Blogs, preprint servers, Search engines, Scirus, Google Scholar,
ChemIndustry, Wiki-Databases, ChemSpider, Science Direct, SciFinder, Scopus.
Information Technology and Library Resources: [5L]
The Internet and World Wide Web, Internet resources for chemistry, Finding and citing
published information.
Unit-II DATA ANALYSIS [15L]

The Investigative Approch:
Making and recording Measurements, SI Unit-s and their use, Scientific methods and design
of experiments.
Analysis and Presentation of data:
Descriptive statistics, Choosing and using statistical tests, Chemometrics, Analysis of
variance (ANOVA), Correlation and regression, Curve fitting, fitting of linear equations,
simple linear cases, weighted linear case, analysis of residuals, General polynomial fitting,
linearizing transformations, exponential function fit, r and its abuse, Basic aspects of multiple
linear egression analysis.
Unit-III METHODS OF SCIENTIFIC RESEARCH & WRITING SCIENTIFIC
PAPERS [15L]
Reporting practical and project work, Writing literature surveys and reviews, Organizing a
poster display, Giving an oral presentation.
Writing scientific papers:
Justification for scientific contributions, bibliography, description of methods, conclusions,
the need for illustration, style, publications of scientific work, Writing ethics, Avoiding
plagiarism.
Unit IV: CHEMICAL SAFTEY & ETHICAL HANDLING OF CHEMICALS [15L]
Safe working procedure and protective environment, protective apparel, emergency
procedure, and first aid, laboratory ventilation, safe storage and use of hazardous chemicals,
procedure for working with substances that pose hazards, flammable or explosive hazards,
procedures for working with gases at pressures above or below atmospheric- safe storage and
disposal of waste chemicals, recovery, recycling and reuse of laboratory chemicals, procedure
for laboratory disposal of explosives, identification, verification and segregation of laboratory
waste, disposal of chemicals in the sanitary sewer system, incineration and transportation of
hazardous chemicals.
Reference books:
1.Dean, J. R., Jones, A. M., Holmes, D., Reed, R., Weyers, J., & Jones, A., (2011),
Practical skills in chemistry, 2nd Ed., Prentice Hall, Harlow.
2.Hibbert, D. B., & Gooding, J. J., (2006), Data analysis for chemistry, Oxford University
Press.
3.Topping, J., (1984), Errors of observation and their treatment, 4th Ed. Chapman Hll,
London.
4.Harris, D. C., (2007), Quantitaive chemical analysis, 6th Ed., Freeman Chapters 3-5
107
5.Levie, R. de., (2001), How to use Excel in analytical chemistry and in general scientific
data analysis, Cambridge Univ Press 487 pages.
6.Chemical safety matters-IUPAC-IPCS, Cambridge University Press, 1992.
7.OSU safet manual 1.01
108
Fees for M. Sc. (Choice Based Credit System) course:
Open category
No. Account Head Amount (Rs.)
1. Tuition fee 1000/-
2. Laboratory fee 6000/-
3. Registration form fee 25/-
4. Registration fee 850/-
5. Library fee 1000/-
6. Gymkhana fee 200/-
7. University sports and cultural activities 30/-
8. Disaster Relief fund 10/-
9. Group insurance 40/-
10. Vice-Chancellor‟s fund 20/-
11. e-Charges 20/-
12. e-Suvidha 50/-
13. Identity card fee 50/-
14. Student welfare 50/-
15. Magazine 100/-
16. Utility 250/-
17. Admission processing fee 200/-
18. Other fees / Extracurricular activities 250/-
19. Development fee 500/-
20. Computer/Internet 500/-
Total 11, 145/-
Refundable deposit:
1. Caution money Rs. 150/-
2. Library deposit Rs. 250/-
3. Laboratory deposit Rs. 400/-
Total Rs. 800/-
*Examination fees (SEMESTER--I & II): Rs. 1549/-
109
Reserved category
No. Account Head Amount(Rs.)
1. Admission processing fee 200/-
4. Group Insurance 40/-
7. e suvidha 50/-
8. Registration fee for M. Sc. SEMESTER- I only 850/-
9. Registration form fee 25/-
Total 1295/-
Refundable deposits
1. Caution money Rs. 150/-
2. Library deposit Rs. 250/-
3. Laboratory deposit Rs. 400/-
Total Rs.800/-
 Examination Fees (SEMESTER- I & II): Rs. 1549/-
The procedure for providing the Photo / Xerox copies of answer sheets and revaluation
 Students should submit their forms for photocopy (i.e. verification) / revaluation (i.e.
rechecking) within ten working days from the date of declaration of the results or on
issue of the statement of marks by the department.
 No application after the due date will be entertained on any ground whatsoever.
 The respective results will be displayed on the notice boards if any changes or
otherwise.
Form fees for photocopies and revaluation : Rs. 10/-

Charges for photocopies : Rs. 100/- per paper
Charges for revaluation : Rs. 500/- per paper
For reserve categories charges for photocopies : Rs. 50/- per paper
For reserve categories charges for revaluation : Rs. 250/- per paper
110
Fees for Ph. D. course:
No. Account Head Fee (Rs.)

1. Tuition fee 4000/-
2. Other fees / Extracurricular activities 250/-
3. Admission Processing Fee 200/-
4. Laboratory fee 12000/-
5. Library fee 1000/-
6. Gymkhana fee 200/-
8. Magazine 100/-
10. Group insurance 40/-
12. University sports and cultural activities 30/-
13. Development fee 500/-
14. Utility 250/-
15. Computer/Internet 500/-
16. e-Suvidha 50/-
17. e-Charges 20/-
Total 19,270/-
(A) Refundable deposit Amount(Rs.) (B) Project fee Amount(Rs.)

1. Caution money 150/- 1. Registration fee 1000/-
2. Library deposit 250/- 2. Registration form 25/-
3. Laboratory deposit 400/-
Total 800/- Total 1025/-
111
1. Fees are payable within the stipulated period mentioned in the notification.
2. In case of fresh entrants to the Department, the tuition fees for the first year and the
deposit become due on the date specified in the letter of admission.
3. Notice for the payment of the fees for the second year (SEMESTER- III and IV) would
be put up on the notice board one week prior to the commencement of SEMESTER- III.
4. Fine for the late payment of the tuition fees for the post-graduate courses is fixed as
Rs.2/- during the first week from the last date prescribed for payment of the tuition fees
and 50 paise per day after one week, subsequently.
5. Tuition fees once paid is not refunded.
6. The caution money deposit is refunded when a candidate leaves the Department. A
claim for the refund of caution money deposit must be made in the prescribed form
available in the Department along with the original receipt within one year from the date
of leaving the Department, failing which the deposit will be forfeited.
7. All the research students are required to pay the tuition fees till they submit their thesis.
8. The research student who wishes to discontinue his/her studies is required to pay the
tuition fees till the date of cancellation.
9. Transference Certificate/ Migration Certificate will be issued to the student who wishes
to join other college/University only after clearing all the dues.
The attention of students seeking admission to M. Sc. (Choice-Based Credit System) Degree
course is particularly invited to the following rules relating to the post-graduate studies.
1. That they will be required to attend in each SEMESTER-notless than 75% of the total
number of lectures delivered for each course.
2. That in addition to attendance at lectures and practicals, they will be required to carry out
regularly the work assigned to them in the form of essays, problems, tutorials, etc. They
shall be required to maintain a record in a properly bound journal. The work carried out
by the students shall be reviewed by respective teacher/s at the end of each SEMESTER-.
3. That the work that will be assigned to them in the form of essays, tutorials etc. shall be in
addition to the practical work that they are required to do for examination.
The office working hours for students and visitors are from Monday to Saturday between
11.00 a.m. and 4.00 p.m. with half an hour recess between 1.00 p.m. and 1.30 p.m. The office
will remain closed on all Sundays, Bank holidays and on second and fourth Saturdays.
112
10. CAREER OPPORTUNITIES IN CHEMISTRY
113
Reproduced with kind permission of Indian Chemical
Society (Mumbai Branch)
Preface
It is being felt that meritorious students do not continue to study Chemistry at advanced
level due to a variety of reasons such as better job opportUnit-ies in other steams. As
knowledge of Chemical sciences plays a vital role in human society, it is essential that for
a balanced society. It has good teachers and researchers in Chemistry both in academic
and Industry. It was felt by the Mumbai Chapter of Indian Chemical Society that quite
often students do not have a clear picture of the different avenues for chemists. In this
booklet it is attempted to give a general picture where chemists can make their
contribution in academics, research and in industry.
Indian Chemical Society Mumbai Branch conducts an Annual Aptitude Test in Chemistry
to motivate students to take challenging careers in chemistry. Lectures on career guidance
are also arranged especially for students of chemistry. The compilation was prepared by
Dr. D. B. Naik, Applied Chemistry Division, BARC in order to provide information on
career opportUnit-ies in Chemistry especially at doctoral level. While every care is taken
to ensure accuracy of information, students are requested to check the details with
individual research institution. It is hoped that the present compilation will be use to
young students in choosing a right career of their choice.
Indian Chemical Society (Mumbai Branch)

Career opportunities in Chemistry
Knowledge of Chemistry plays a vital role in human society. In the technological
development of 20th century chemistry contributed immensely in synthesis of new and
high purity materials, their characterization and applications, understanding of reaction
mechanisms etc. Scientific and technological development has pronounced effect on
health and comforts of human beings. In this developmental process, new materials and
processes have been adopted which have led to the deterioration of the environment. For
better environment management clean production processes and also methods for waste
management have become most important. Irrespective of developments in other fields of
science, chemical sciences will sustain its important role in human society. Present day
chemistry is not just synthesis and characterization of substances. It encompasses physical
and biological sciences. There is an ample scope to apply the knowledge of chemical
sciences. The present statues of chemistry teaching in various academic institutions is
summarised below.
1. Chemistry teachers in schools:
Graduates in Chemistry with B. Ed., degree are employed to teach chemistry subjects to
school students. As young children are curious about more and more of the natural
processes, there is always excitement in teaching in schools. Sometimes, these teachers
will be required to teach Mathematics and Physics also.
2. Lecturers in colleges:
As an independent subject, chemistry is taught from first year junior college onwards.
Usually post graduates in Chemistry teach in junior colleges. In degree colleges, as
students major in Chemistry subject, Doctorates in addition to post graduates are
114
employed to teach chemistry. Recently, UGC (University Grant Commission) has started
Lectureship exams. It is mandatory to clear these exams for getting employed as lectures.
Some of the colleges especially in bigger cities are equipped with good laboratories
where in it is possible to carry out research work.
3. Post graduate teachers Doctorates in different branches of chemistry teach post
graduate students in different universities. In addition to teaching, there is scope to carry
out research work and guide doctoral students.
Presently the emoluments for college as well as post graduate teachers are fairly
attractive.
In India, very few of the University departments have good research facilities. There are
quite a number of National Research Centres spread over the country where modern
facilities are available to carry out frontline research.
1. Indian Institute of Science Bangalore, Bangalore 560 012
Departments of Physical and Inorganic Chemistry, Organic Chemistry, Solid State
Chemistry Unit-, Material Research Centre.
2. Indian Institute of Technology Bombay, Powai, Mumbai - 400 076.
Department of Chemistry offers 5 years integrated and 2 years M. Sc. course in
Chemistry. For integrated M. Sc. course admission is through JEE. For 2 years M. Sc.
course entrance test is held in July. For admission to Ph. D. interviews are held in June
and December. For post doctoral research, opportunities are available as research
associate. Fields of research available are Bioorganic Chemistry, Bioinorganic
Chemistry, Synthetic Organic Chemistry, Electrochemistry and Theoretical Chemistry.
3. Indian Institute of Technology Madras, Chennai - 600 036,
4. Indian Institute of Technology Kanpur - 208016,
5. Indian Institute of Technology Kharagpur - 721 302.
Offers one 5 years integrated M. Sc. course in Industrial Chemistry and two years M.
Sc. course in Chemistry. It also offers Ph. D. program in different fields of chemistry.
Research fields are pharmaceutical and allied chemistry, industrial chemistry and
material science.
6. Indian Institute of Technology Delhi, New Delhi -
Offers 2 years M. Sc. in Chemistry, Entrance for M. Sc. is through a written test. It also
offers M. Tech. course in Modern Methods of Chemical analysis for which entrance is
through GATE and NET tests.
7. Indian Institute of Technology Gowhati -
For integrated post graduate courses, candidates are selected by joint entrance test. IITs
announce their Ph. D. programmes in different disciplines in National Newspapers
every year in and candidates are selected after interview.
8. Indian Association for Cultivation of Science, Jadhavpur, Calcutta - 700 032.
(Photochemistry, Organic Synthesis, Theoretical Chemistry, Biochemistry)
Council of Scientific Industrial Research (CSIR) (www.csir.ernet.in) has a number of
laboratories spread all over country where chemical and allied research is carried out.
115
Its head quarters is in New Delhi, CSIR, Rafi Marg, New Delhi,
email: csirhq@sirnetd.ernet.in.
Some of the major research institutes of CSIR where opportUnit-ies for research in chemistry
exist are given below.
1. Central Drug Research Institute
Chathar Manzil Road, PB 173
Lucknow - 226 001
Development of new drugs and diagnostics, cellular and molecular studies to
understand disease processes and reproductive physiology. Systematic evaluation of
medicinal properties and natural products. Biochemical, Molecular Biological
Chemical, pharmacological research.
2. Central Leather Research Institute
Adyar, Chennai 600020 : clrim@giasmd01.vsnl.net.in
www.clri.org
CLRI conducts for AnnaUniversity courses in leather technology leading to B.Tech.,
M.Tech., and Ph.D. degrees. CLRI also offers number of short term and long term
vocational programmes.
3. National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008
Research in Advanced materials, Biotechnology, Catalysis, Organic Chemical
Technology, Pilot plant studies, Biotechnology.
4. Indian Institute of Chemical Technology, Hyderabad - 500 007.
Studies of agrochemicals, drugs and pharmaceuticals, inorganic chemicals and
materials, Organic synthesis, polymers, catalysis, process development.
5. Regional Research Laboratory Trivandrum, Kerala - 695019
To develop technology for optimum use of regional resources, to develop industry in
the region through research, development and technology transfer, Photochemistry,
Organic synthesis.
6. Regional Research Laboratory, Bhubaneshwar - 751013
Research in problems relating to industry and raw materials of the region.
7. Central Electrochemical Research Institute
Karaikudi 630006, Tamil Nadu
Email : cecrik@cscecri.ren.nic.in
Research in both the frontier areas of electrochemistry and the problems of relevance to
Indian industry. It is playing a leading role in human resource development for the
electrochemical and related industries. In this regard CECRI offers a variety of courses
to scientific and technical personnel in industries, government and academic
institutions.
8. Regional Research Laboratory, Jammu-Tawi 180 001
Email: rrlj@nde.vsnl.net.in
Drug and medicinal plants, introduction of exotic plants, plant chemistry, extraction and
processing of drugs.
116
9. Central Salt and Marine Chemicals Research Institute,
Waghawadi Road, Bhavanagar - 364 002
10. National Institute of Oceanography
Miramar, Panaji Goa - 403004
Email : ocean@csnio.ren.nic.in
Investigations on physical, chemical, geological and biological oceanography
11. Central Glass and Ceramic Research Institute
196, Raja Mallik Road, Jadavpur, Kolkata - 700032.
Email: cscgcri@giascl.l.vsnl.net.in
Research on synthesis and applications of speciality glasses.
12. Centre for Cellular and Molecular Biology (CCMB)
Hyderabad - 500 007.
Research in frontier and multidisciplinary areas of modern biology with a view of
aiding biochemical and bioengineering
13. Indian Institute of Petroleum
Dehra Dun - 248 005
Email: iipddn@de12.vsnl.net.in
R & D in the field of petroleum, natural gas and petrochemicals and utilisation of
petroleum products.
14. National Environmental Engineering Research Institute
Nehru Marg, Nagpur, 440 020
Email: dirneeri@nagpur.dot.net.in
Studies in Chemical, biological and microbiological research, instrumentations and field
research; water, studies related to sewage and industrial waste, air pollution, industrial
hygiene
15. Regional Research Laboratory, Jorhat, Assam 785 006
Research in coal, petroleum, pulp and paper, natural product chemistry, cement, drugs,
synthetic organic chemicals, essential oils, medicinal plants, material science.
16. National Metallurgical Laboratory
Jamshedpur 831 007, Singhbhum Dist. Bihar
Email: nml@csnnml.ren.nic.in
Ore dressing, production, physical and chemical metallurgy
17. National Institute of Science, Technology & Development Studies
Hill Side Road, New Delhi - 110 012
Email: postmast@csnistad.ren.nic.in
Conducts research on technological and social change and resource planning and
utilisation for regional development.
3. Research Fellowships:After post graduate degree in Chemistry, one can carry out
research work leading to doctoral degree (Ph.D.) in University departments, CSIR
laboratories, Indian Institutes of Technology, and other national centres. National
Eligibility Test (NET) examination is held twice the year for selection and award of
117
Junior Research Fellowships (JRF). A total of nearly 1000 are normally selected for
the grant of fellowship both from CSIR and UGC. Award of SRFs and Research
Associates is done through personal interviews by Expert Committees. Senior
Research Associates (erstwhile Pool Officers) scheme is meant to support highly
qualified S & T personnel through temporary placement.
4. Post Doctoral Research Fellowships:After completion of doctoral degree in various
branches of Chemistry, these researchers can carry out post doctoral work at different
institutes around the world. At many Universities and research centres, professors are
able to offer these fellowships from their funds. Many a times this goes through
individual contacts / previous acquaintances. With advent of internet these positions
are advertised. There are some government as well as semi government agencies
which offer fellowships to carry out post doctoral fellowships. Following are the few
agencies.
1. Alexander von Humboldt Foundation
Jean-Paul Str. 12, D-53173, BONN, Germany
2. German Academic Exchange Service (DAAD)
New Delhi Office,
176, Golf Links, New Delhi 110 003
In India, under CSIR research associate fellowship, one can carry out post doctoral
research work in different CSIR laboratories and other research establishments. In
recent years, Department of Atomic Energy has started offering a limited number of
K. S. Krishnan post doctoral fellowship. Usually the advertisements come in National
newspapers and the selected candidates carry out research in different DAE Unit-s.
There is also possibility of candidates being absorbed in regular service.
5. Opportunities in Industry
Besides the opportUnit-ies in academics, there is an ample scope in industry for
chemistry graduates / postgraduates / Ph.D.'s. The role of chemicals in our day-today
life is increasing dramatically from household goods, medicines, functional materials
to environmental friendly technologies, etc. Several of technologies are being
replaced with new ones, superior products are being launched in the market. Indian
chemical industry too is responding to these changes. With increasing globalization
and privatization several multinational companies have started their business in India.
Well trained professionals in chemical sciences could help in building strong Indian
Chemical Industry which will not only cater to domestic market but will also offer
products at competitive price in the international market. Specialists in each area
would find opportUnit-ies in industry.
Organic chemists: Organic chemicals (bulk and fine), pharmaceuticals,
agrochemicals, food products, development of new technologies, etc.
Inorganic chemists: Inorganic and metalloorganic compounds, inorganic materials for
electronic industry etc.
Analytical chemists: Quality control employing modern instrumental techniques,
better and efficient detection methods etc.
Physical Chemists: Research and Development departments in institution/industries
dealing with modern materials including nanomaterials, catalysts, polymers, modern
techniques for characterization of materials etc.
118
11. Ph.D admissions in the Depatment of Chemistry will be done as per the guidelines
issued time to time by UGC, New Delhi and University of Mumbai, Mumbai. The
Minimum stantadards and procedure for the awards of M.Phil and Ph.D Degree will be as
per the as per the circular Univ./VCD/947 of 2018 dated 15th June 2018 given by
University of Mumbai
119
12.RESERVATION FOR M.Sc in CHEMITSRY
Statement showing the number of seats available for students of different categories for admission to M. Sc. Degree course in different branches
of chemistry for the year 2020-21
Number of Seats for Reserved Category Students Reserved General

Total Category Category
Branch
Seats DT(A)
SC ST NT(B) NT(C) NT(D) OBC SBC
(VJ) 62% 38%
E.W.S.
13% 7% 3% 2.5% 3.5% 2% 19% 2% 10%
#
Organic 20 2 2 1 1 3 1 2 12 7 + 1@
*
Analytical 20 3 1 1 1 4 2 12 7+1
Inorganic 20 2 2 1 1 3 + 1* 1 1 + 1@ 13 6 + 1ф
#
Physical 20 3 1 1 1 1 4 13 6+1
2
Total 80 10 6 2 2 3 2 15 2 50 30
8
1% seats are reserved for Orphan students (marked by ф)

3% seats are reserved for Other University students (marked by *)
120
#
3% seats are reserved for Physically Handicapped students (marked by )
@
3% seats are reserved for the following category students (marked by )
1. Wards of the Central / State Govt. employees / officers who have been transferred
2. Wards of the present / past defence personnel
3. Students obtaining dexterity at National / State level Sports/ Cultural activities
4. Widow / Deserted female students
5. Wards of the Freedom Fighters
121
122
13. INFORMATION FORADMISSION TO M.Sc. DEGREE COURSESIN
CHEMISTRY.
INTRODUCTION
A candidate for being eligible for admission to the M. Sc. Degree in Chemistry must have
passed the Bachelor of Science degree examination with Chemistry as a major subject with
6/3 Unit-s or an examination of another University recognized as equivalent thereto. The M.
Sc. (By Paper) degree course in Chemistry is of four-SEMESTER- duration. The structure of
the M. Sc. degree course by papers is as per the syllabus given.
INSTRUCTIONS TO APPLICANTS:
GENERAL INSTRUCTIONS TO APPLICANTS FOR FILLING UP THE

APPLICATION FORM
Please read the handbook carefully before filling the admission form.
1. Merit is the only criterion for admission and seats are reserved as per Government
of Maharashtra’s directives in this connection.
2. Admissions of students belonging to the reserved category i.e.
SC/ST/DT/NT/OBC/SBC etc. are as per Government of Maharashtra’s directives.
Application form must be accompanied by caste certificate issued by the Competent

Authority. In case of OBC/SBC and DT/NT students, the requisite Non-Creamy
Layer certificate issued in the Current Financial Year should be appended to the
application. Application form without proper certificates will not be accepted.
3. There are no agencies operating on behalf of the Department and there is no

capitation fee or donation in regard of admissions. Be careful of any persons
claiming to offer admission to the Department. No extraneous considerations
should be brought to exert pressure on the admissions committee. It will be strictly
dealt with. We take pride in fairness and openness in admissions and all matters
and give justice to one and all.
4. Applications must be accompanied by:
a) Attested copies of the mark-sheets of First, Second and Third Year B.

Sc.examinations along with their originals.
b) Date of birth certificate (H.S.C. passing certificate/School Leaving certificate

etc.)
123
c) Students coming from the University other than University of Mumbai are
required to obtain a provisional statement of Eligibility from the Eligibility
Section, University of Mumbai, Dr. Ambedkar Bhavan, Vidyanagari, Mumbai -
400 098.
d) Account for any break in education should be mentioned in the form and the
documentary evidence for the same must be provided along with the application
form.
ADDITIONAL INSTRUCTIONS FOR FILLING UP THE APPLICATION FORM
1. Students are advised to indicate their order of preference for all the four disciplines
(Organic, Analytical, Physical and Inorganic Chemistry).
2. Applicants who have passed B. Sc. Examination from OTHER UNIVERSITIES should
mention the aggregate marks secured by them in Chemistry (Theory and Practicals
separately) at the First, Second and Third Year B. Sc.
After the scrutiny of admission forms submitted by the students, a synopsis showing the
merit numbers of the students for different categories will be displayed on the notice
board and on the web-site of the University. No individual correspondence will be
made in this regard. It is the responsibility of the candidates to visit the notice Board
and web-site regularly. It would be the responsibility of the student tocheck for any
errors in the synopsis and point out to the Head of the Department in writing within
3 days of the display of the synopsis. No complaints will be entertained thereafter.
The detailed schedule for admission will be displayed on the same day. It would be the
responsibility of the student to check the schedule and present himself/herself for
admission on the day mentioned in the schedule.
Pleading ignorance about information displayed on the notice board and the web-site
shall not be entertained.
APPLICANTS SUCCESSFUL IN GETTING ADMISSION WILL BE REQUIRED

TO GO THROUGH THE FOLLOWING ADMISSION PROCEDURE:
1. Submit the original Statement of Marks of T. Y. B. Sc. Examination.
2. Open Category Students: Pay prescribed fee of Rs. 11,145/- [including Rs. 850/-
Registration fee and Rs.25/- for the form of Registration] within the stipulated period and
produce the receipt in the office of the Department of Chemistry.
124
3. Reserved category Students: Pay prescribed fee of Rs. 1295/- [including Rs. 850/-
Registration fee and Rs. 25/- for the form of Registration] within the stipulated period and
produce the receipt in the office of the Department of Chemistry.
4. In addition, all the students have to pay the refundable deposits of Rs. 800/- (Caution
money: Rs. 150/- + Library deposit: Rs.250/- + Laboratory deposit: Rs.400/-)
CANCELLATION PROCEDURE
Cancellation of Seats makes a heavy demand on the time spent by the administration. Hence
the following procedure must be scrupulously followed.
Application for cancellation of seat should be addressed to the Head of the Department
in duplicate as per the Proforma B. Application for refund of fees should be
addressedto the Registrar, University of Mumbai in Duplicate as per the Proforma
C and submitted to the Head of the Department.
Kindly note that refund of tution fees will be given only if the student takes admission to
one of the University of Mumbai’s affiliated colleges.
Refund of tution fees will not be made if the student takes admission to any other
college/institute, not affiliated to University of Mumbai, and/or does not take
admission to any course.
125

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University of Mumbai

Tel: +91(022) 2654 3353

3. LABORATORY FACILITIES FOR PAPER AND RESEARCH STUDENTS

5. HOSTEL ACCOMODATION FOR STUDENTS

NAME: Dr. (Smt.) Manjusha Karve

PAPERS 30 Ph. D STUDENTS 02

NAME: Dr. Shivram S. Garje

PAPERS 62 Ph. D STUDENTS 08 (completed)

PAPERS 85 Ph. D STUDENTS 13 (completed)

NAME: Dr. Rajesh M. Kamble

PAPERS 33 Ph. D STUDENTS 02 (completed)

PAPERS 48 Ph. D STUDENTS 16(completed)

NAME: Dr. Suresh D. Pawar

PAPERS 28 Ph. D STUDENTS 08 (ongoing)

PAPERS 20 Ph. D STUDENTS 04 (ongoing)

NAME: Dr. Purav M. Badani

PAPERS 23 Ph. D STUDENTS 04 (ongoing)

PAPERS PUBLISHED: - Ph. D STUDENTS -

NAME: Bhushan B. Popatkar

PAPERS 02 Ph. D STUDENTS -

PAPERS PUBLISHED: 21 Ph. D STUDENTS 05 (ongoing)

NAME: Dr. Arun K. Kadu

PAPERS 05 Ph. D STUDENTS 02 (ongoing)

PAPERS PUBLISHED: 41 Ph. D STUDENTS 15 (completed)

 Honors/Awards  Performance based Incentive award, University of

The Salient features of Choice-Based Credit System (CBCS) are as follows:

Admission to M. Sc. Choice-Based Credit System (CBCS) Course

* Practical component involves 16 h per week laboratory work for 15 weeks.

List of Books for further reading:

CHEM-102: INORGANIC CHEMISTRY-I

CHEM 103: ORGANIC CHEMISTRY-I

2.4 Axial and Planar chirality:

CHEM-106: INORGANIC CHEMISTRY PRACTICAL-I

Synthesis, Purification and Analysis of the following Inorganic Preparations:

CHEM 108: ANALYTICAL CHEMISTRY PRACTICAL-I

*Practical component involves 16 h per week laboratory work for 15 weeks.

CHEM 201: PHYSICAL CHEMISTRY-II

Unit-II APPLIED ASPECTS OF QUANTUM CHEMISTRY [15L]

orbital and spin angular momentum, spin orbitals.

Unit-III APPLICATIONS OF THERMODYNAMICS AND ELECTROCHEMISTRY

Unit-IV MOLECULAR REACTION DYNAMICS [15L]

List of Books for further reading:

CHEM 203: ORGANIC CHEMISTRY-II

CHEM 204: ANALYTICAL CHEMISTRY-II

CHEM 205: PHYSICAL CHEMISTRY PRACTICAL-II

CHEM 207: ORGANIC CHEMISTRY PRACTICAL-II

No. of CREDITS: 24 TOTAL MARKS: 600

CHEM 311: SOLID STATE CHEMISTRY

CHEM 312: SPECTROSCOPY

List of Books for further reading:

CHEM 316: PHYSICAL CHEMISTRY PRACTICAL-III

List of reference Books for Practicals and Spectral Interpretaion:

Unit-I HETEROGENEOUS CATALYSIS [15L]

Unit-IV SURFACE CHARACTERIZATION TECHNIQUES [15 L]

CHEM 315: EC-II: SOME SELECTED TOPICS IN PHYSICAL CHEMISTRY

No. of CREDITS: 24 TOTAL MARKS: 600

CHEM 321: SOLID STATE CHEMISTRY-I

CHEM 322: COORDINATION AND BIO-INORGANIC CHEMISTRY

Unit-II MAGNETIC PROPERTIES OF COMPLEXES [15L]