13 Why Do We Fall Ill
13 Why Do We Fall Ill
13 Why Do We Fall Ill
Example 1: Can you explain the difference between a healthy and a disease-free state
of the human body?
Solution: The state of not having any disease is not the same as being healthy.
Good health is the ability of an individual to realize his or her full potential. Consider, for
example, an athlete who is tired after running about hundred metres. The athlete cannot be
called a diseased person. However, he is not healthy either. Therefore, one can have poor
health without having any identifiable disease.
Types of Health
The word ‘hygiene’ is derived from the Greek word ‘Hygieia’. In Greek mythology, Hygieia is
the goddess of health, cleanliness and sanitation.
Concept Builder
Personal hygiene
Here are certain healthy habits that we all must follow to maintain personal hygiene.
Here are some of the steps that need to be taken to ensure effective social hygiene.
Making provisions for clean drinking water
Making provisions for family welfare education
Establishing healthcare services
Making provisions for proper waste disposal and sanitation facilities
Controlling diseases by providing vaccination, medical aid and medicines
Solved Examples
Example 2: Why are social equality and harmony necessary for good personal
health?
Solution: Social equality and harmony are important for good personal health. Social
equality means equal access to education, hygienic environment, health facilities, etc. Social
harmony refers to the peaceful interactions between the various individuals and groups
constituting the society. Individual health prospers when conditions for social equality and
harmony are present. This in turn adds to the overall health and well-being of the
community.
Disease
According to WHO, chronic diseases are responsible for 60% of all deaths worldwide.
Causes of Disease
There can be a number of causes for disease. These are broadly divided
into immediate causes and contributory causes (as is shown in the figure).
Solved Examples
Example 3: A number of children consume contaminated food and water. Yet, only
some get diarrhoea while the others remain disease-free. Why is this so?
Solution: This happens because of the difference in the levels of immunity. A healthy
body or a well-nourished body is less likely to catch a disease when exposed to disease-
causing agents. This is because it has a strong immune system. On the other hand, a poorly
nourished body will easily become diseased due to its weak immune system.
We often describe 'health' as a state of a person who is free from any kind of disease.
However, it is an incomplete definition of health. A person need not only to be free from
any physical disease, but he must also have a sound mind to be called a healthy individual.
So we can define health as a state of complete physical, mental and social well-being.
The word disease is derived from two words ‘disturbed ease’. It may be defined as any
condition that can lead to discomfort, distress, health problems, and even death of the
affected person. In this condition, a part of body is no longer healthy or it is malfunctioning.
Acquired and Congenital Diseases
Acquired diseases
Diseases acquired by individuals during their lifetime are called acquired diseases. Such
diseases are mostly non-inheritable. They can be classified as follows:
1. Infectious diseases
2. Non-infectious diseases
Degenerative diseases: These are caused by the malfunctioning of vital organs. Examples
include diabetes and cancer.
Deficiency diseases: These are caused by the deficiency of one or more nutrients.
Examples include night blindness, marasmus and anaemia.
Allergy: These are caused due to hypersensitivity towards certain substances, e.g. dust,
pollen, etc. Asthma and hay fever are two such diseases.
Congenital diseases
Diseases that are present in individuals from birth are called congenital diseases. They may
be caused due to some mutations or metabolic disorders. They are often inheritable.
Examples of such diseases include various genetic diseases such as haemophilia, autism,
sickle-cell anaemia, Klinefelter’s syndrome and Turner’s syndrome.
Know More
On the basis of spread of disease, diseases are classified in the following manner.
All communicable diseases are infectious, but all infectious diseases are not communicable.
Non-infectious Diseases
Genetic disorders: Diseases that are caused by changes in the genetic makeup, or DNA of an
individual. These diseases may get passed on from parents to their children. Examples
include haemophilia and thalassaemia.
Dietary deficiency diseases: These diseases are caused due to deficiency of some important
dietary components in our body. These nutrients are highly important for normal growth
and development of our body, and thus their lack can result in diseases.
Allergy: Allergy refers to a sudden, unpredictable reaction of body to any particular
substance, or allergen. Some common allergens include dust, pollens, spores, certain
medicines, cosmetics, etc. These allergens most commonly affect the skin, respiratory
system, digestive tract, eyes, etc.
Diseases caused by physical and chemical agents: Heat stroke or sunburn can be caused by
the physical agents. Some diseases may also be caused by chemical agents, such as
mercury, lead, potassium cyanide, etc.
Infectious Agents
Viruses: They are very tiny organisms and are visible only with the help of an electron
microscope
. They cannot grow, multiply or reproduce on their own. They need to infect a host cell to get
the required machinery to perform these functions. The genetic component of a virus may be
made of DNA or RNA. RNA-containing viruses are called retroviruses.
Examples of RNA viruses include SARS virus (Severe Acute Respiratory Syndrome-causing
virus), polio virus, influenza virus, hepatitis C virus, retrovirus (example, HIV).
Examples of DNA viruses include bacteriophage (virus that infects bacteria) and herpes
virus.
Viron: A virion is a single viral particle consisting of an outer protein shell (called capsid)
and an inner core of genetic material (either DNA or RNA).
The smallest known virus is Circovirus and the biggest known virus is Megavirus.
Infectious Agents: Bacteria and Fungi
Bacteria: Bacteria are unicellular prokaryotic organisms. They reproduce very quickly.
They are larger than viruses. Only some bacteria cause diseases; others are useful in
nature.
.Examples of diseases caused by bacteria include whooping cough, typhoid, cholera, anthrax,
tuberculosis, diarrhoea, diphtheria, tetanus, syphilis, gonorrhoea
in nature, i.e., they lack chlorophyll. They are mostly multicellular and have thread-like
bodies.
.Examples of diseases caused by fungi include athlete’s foot, candidiasis and ringworm.
Not all bacteria are harmful for humans. In fact, the disease causing bacteria are less than
1%. Some bacteria that live in our body are actually good for us. For
example, Lactobacillus acidophilus is a harmless bacterium that resides in our intestines. It
helps us digest food, destroys some disease-causing organisms and provides nutrients to
our body.
Examples of diseases caused by protozoa include amoebiasis, kala azar, malaria and African
sleeping sickness.
Multicellular animals (e.g., worms): Worms are parasites that infect the intestines of
human beings and animals. Roundworms, pinworms, hookworms and tapeworms are some
examples of disease-causing worms.
Know More
Why do we have to identify the causal agent of a particular disease? Is there any
advantage in having information about the disease-causing organism?
The type of causal agent of a disease determines the type of treatment that can be used for
curing the disease. Since all microorganisms are different in structure, a medicine or drug
manufactured to disrupt the structure/function of one microorganism may not have any
effect on another microorganism.
penicillin blocks the synthesis of the cell wall in bacteria. Therefore, this antibiotic can be
used effectively against a large number of bacteria. However, it cannot be used on other
microorganisms like viruses.
Modes of Transmission of Diseases
Transmission of Diseases
We use various means of transport to travel from one place to another. In the same way,
pathogens causing infectious diseases also use certain means of transport (or to be more
specific, modes of transmission) such as air, food and water to enter the bodies of living
organisms.
Infectious diseases are caused by microorganisms such as bacteria, viruses, etc. that get
into the body and cause problems. Some — but not all — infectious diseases spread
directly from one person to another. Such diseases are called communicable diseases.
Diseases: Modes of Transmission
Note: AIDS is a disease that spreads through sexual contact and also via blood to
blood contact.
Sexual contact: The sexual act involves close contact between two people. This may lead to
the transfer of diseases such as syphilis, gonorrhoea and AIDS. These diseases are known
as sexually transmitted diseases. Note that casual physical contact such as handshaking,
hugging and kissing do not lead to the transfer of these diseases.
Direct contact: Certain diseases spread when one comes in contact with the diseased
person or on using the articles used by him. Swine flu, athlete’s foot, ringworm,
conjunctivitis and German measles are diseases that spread in this manner.
Whiz Kid
Water and food: When the excretions from an infected person get mixed with drinking
water, the water becomes contaminated with disease-causing microorganisms. Diseases
are caused when this contaminated water is consumed by other individuals. Such diseases
are called waterborne diseases.
Any food prepared using this same water can also cause diseases when consumed. These
diseases are known as food-borne diseases.Food and water can also be contaminated by
various insects like mosquitoes, houseflies, cockroaches, etc.Examples of such diseases
include cholera, typhoid and hepatitis A.
Vectors: These are organisms that carry disease-causing microorganisms from an infected
person to others. Though a vector carries pathogens, it itself is not infected by them.
Diseases spread through vectors are known as vector-borne diseases. Examples of such
diseases include malaria, filariasis, dengue, rabies and plague.
Now that we have studied how microbes make their way into the human body, let us find
out what happens after their entry.
The microbes, upon entering the body, infect specific tissues and organs. These infections
of tissues and organs manifest as diseases. Thus, the signs and symptoms of any disease
depend upon the affected tissues or organs.
It is believed that microbes affect specific organs depending on the site of their entry. Say, a
microbe enters our body through the nose. Where is it likely to reach? The lungs, of course!
For example, the tuberculosis-causing bacterium enters the human body via the nose and
affects the lungs. Or let us suppose a microbe enters our body through the mouth. In this
situation, it either stays in the gut lining (as is the case with the bacterium causing typhoid)
or it affects the liver (as is the case with the virus causing jaundice). However, this theory is
not true always. Let us see how.
The AIDS virus enters the body through the sex organs, but it later spreads to all the
lymph nodes
. Similarly, the malaria-causing Plasmodium enters through the blood, then goes to the liver
and later infects the RBCs.
Specific Defence Mechanism
an invading pathogen. Once engulfed, some part of the pathogen remains on the surface of the
macrophage. This remaining part is called an antigen.
Lymphocytes: These white blood cells generate antibodies against the antigens.
Antibodies: Specific antibodies are generated for specific antigens. The antibodies either
prevent the entry of the pathogen into the cell or kill it.
Sometimes ordinary substances such as pollen-dust, vegetables and fruits may also act as
antigens. The body produces antibodies in its defence and this causes allergies.
Concept Builder
The immune system, as we have studied, develops the strength to fight off microbes. It is
made up of special cells, proteins and organs that protect the body against invading
microorganisms. The cells that are a part of the immune system are white blood cells
(WBCs) or leukocytes. These cells destroy pathogens. WBCs are produced in the thymus,
the bone marrow and the spleen (the lymphoid organs).
Treatment and Prevention of Diseases
Disease Prevention
Disease prevention refers to certain measures which should be taken so as to lower our
chances of getting diseased. Broadly speaking, there are two ways of preventing diseases.
Certain diseases need specific methods of prevention, i.e., vaccination. You must have seen
on television or read in the newspapers about the Pulse Polio day, when children in the age
group of 0−5 years are given the polio vaccine. What is a vaccine? What is meant by the
term vaccination? And what is the difference between vaccination and
immunisation?
Vaccination is defined as the protection of the body from infectious diseases by the
administration of some agents that mimic disease-causing microbes. The agents can
be suspension of killed or attenuated
microbes, or substances that mimic the disease-causing germs. These agents are known
as vaccines. They make the body produce antibodies. The antibodies remain in the blood
for a long duration. When the disease-causing germs enter the body a second time, the
antibodies destroy them.
Immunisation is the process whereby an individual’s immune system is fortified
against an infectious agent. This immunity can be achieved through artificial means such
as vaccination.
Mother’s milk is considered very essential for infants. The yellowish fluid colostrum,
secreted by a mother during the initial days of lactation, has abundant antibodies to protect
an infant.
Principle of Vaccination
Vaccination is based on the specific way in which the immune system defends the body.
When the immune system encounters a pathogen for the first time, it reacts against it and
remembers it. Consequently, if the same pathogen strikes again, the immune system reacts
strongly to prevent the body from becoming diseased by the infection again. For example, if
a child has suffered from measles once, then there is almost no chance of the child suffering
from it again.
It logically follows that if we infect the body with something that mimics a pathogen, then
the immune system will remember it and prevent the actual pathogen from causing any
disease. This forms the basis of vaccination.
Vaccines are available against many diseases; for example, tetanus, polio, measles, hepatitis
A and B, whooping cough and yellow fever.
Solved Examples
Example 1: A person shows certain symptoms like loss of appetite, severe coughing
with bloody sputum, chest pain, fever.
1. Name the disease the person is suffering from and its causative agent.
2. How does this disease spread?
3. What treatment should be followed?
4. What precautions should be taken to avoid the disease?
Solution:
Hard
Example 2: Both chicken pox and the common cold are viral infections. Yet why is
that the former occurs only once during one’s lifetime while the latter occurs several
times?
Solution: Chickenpox is caused by the varicella- zoster virus. It spreads through direct
physical contact with the infected person as well as through droplet infection. If a person
has suffered from chicken pox once, then there is almost no chance of him suffering from it
again. This happens because of the specific way in which the immune system defends the
body. When a pathogen (in this case, the chickenpox virus) attacks the body for the first
time, the immune system reacts against it and remembers it. When the same pathogen
strikes again, the immune system reacts strongly to prevent the body from becoming
diseased by the infection again.
Common cold is also a viral disease. It is caused by rhinovirus. However, unlike the
chickenpox virus, the virus causing common cold mutates at a very fast rate. This makes it
difficult for the immune system to remember the common-cold-causing virus.As a result,
the immune system fails to prevent the virus when it infects the body next time. This is why
the common cold occurs several times during one’s lifetime.
History of Vaccination
429 BC: Thucydides, a Greek historian, notices that smallpox survivors do not get re-
infected.
1796: Edward Jenner, an English doctor, invents the vaccination for smallpox.
1896: The vaccines for cholera and typhoid are developed using killed versions of bacteria.
1948: The diphtheria, tetanus and pertussis vaccines are combined into a single DPT
vaccine.
2006: The hepatitis-A vaccine is added to the routine childhood immunization schedule.
Types of Vaccines
(1) Using killed germs: Vaccines can be prepared from dead causal germs, for example,
Salk's vaccine for polio, TAB vaccine for typhoid, etc
(2) Using living weakened germs: Vaccines can be prepared from living causal germs, but
these germs are first treated to become very weak, so that they cannot cause any disease.
Such vaccines can however induce antibody generation when entered into the body.
Examples include vaccines for measles, and BCG vaccine for tuberculosis.
(3) Using living, virulent germs: In some cases, live and fully active (or pathogenic)
germs are introduced into the body to induce antibody generation. For example, cowpox
virus is inoculated as vaccine to induce antibodies against smallpox virus.
(4) Using toxoids: Toxoids are modified, inactive form of harmful toxins produced by
bacteria. Although non-toxic in nature, these toxoids are capable of inducing antibody
generation in body, and thus can be used as vaccines. Toxoid vaccines are used for
diphtheria and tetanus.
Treatment of Diseases
Diseases might occur even after following different preventive measures. In such cases, the
diseases need to be treated. A disease can be treated either by reducing its effect or by
killing its cause.
About 90% of antibiotics are extracted from bacteria, fungi and moulds. The remaining
10% are produced synthetically.
Antibiotics should not be taken unless prescribed otherwise bacteria can become resistant
to them.
Concept Builder
An antibiotic is a drug that kills or slows the growth of bacteria. Antibiotics are a class of
antimicrobials that also include antiviral, anti-fungal and anti-parasitic drugs. These are
basically the chemicals produced by or derived from microorganisms. Certain antibiotics
may be described as broad-spectrum, implying that they can get rid of infections caused by
a wide range of bacteria.
Antibiotics work by killing the disease-causing agents (i.e., bacteria). They do this by
interrupting the chemical processes used by bacteria to make their cell walls. For example,
the antibiotic penicillin blocks the cell-wall formation in bacteria. Some antibiotics stop
bacteria from growing and multiplying.
Solved Examples
Example 3: Why can antibiotics be used effectively against a wide range of bacteria,
but not against other microorganisms such as viruses?
Solution: Antibiotics are drugs that kill or slow the growth of bacteria. In their action, they
are selective only toward bacterial cells as they are produced by certain bacteria which
limit the growth of other bacterial cells. Further, they do not affect the host cells. Viruses
become integrated with the host cells; so, antibiotics cannot target them. This explains why
the use of antibiotics during the common cold does not help much. If there is a bacterial
infection along with the common cold, then the antibiotic will be effective only against the
bacterial infection.
Misuse of medicines:
Medicines are used in the treatement of diseases and they should only be consumed on the
prescription of a doctor. Overdose of medicines can harm our body. For example, overdose
of painkillers may damage the nervous system, excretory system and liver whereas
overdose of antibiotics may lead to stomach ache, nausea, dysentry, rashes etc.
He deliberately infected the child with the cowpox virus. The boy recovered soon after a
slight fever. Then, after a few weeks, Jenner infected the child with the smallpox virus and
found that the boy remained healthy. This happened because the cowpox virus is closely
related to the smallpox virus. Hence, the boy was provided immunity by the cowpox virus
administered before.
You must have heard the old saying, ‘prevention is better than cure’. It is surely better to
prevent a disease from occurring, rather than to cure it afterward. This is because it is
easier to stop something bad from happening in the first place, rather than to fix the
damage later on.
Additionally, treatment measures can be difficult to deal with for the following reasons.
1. Diseases damage the functions of the body, which then takes a long time to become fully
functional again.
2. Sometimes a prolonged treatment may be necessary. Consequently, the affected individual
has to remain bedridden for a long time.
3. Even while being treated, diseased persons may spread the pathogens to others coming in
contact with them.
The practice of intake of alcohol, drugs and tobacco is becoming very common among the
youth. However, these products have very serious and deleterious health concerns.
Tobacco: Smoking and chewing tobacco products have very harmful effects on our body. A
person consuming these products is at a very high risk of various ailments, such as lung
cancer, mouth cancer, heart attack, high pressure, etc. Non-smokers that regularly sit
around a active smoker person and inhale tobacco smoke may also suffer from these
diseases. Such phenomena is known as passive smoking.
Alcohol: Alcohol consumption affects both physical and mental health. It causes damage to
nervous system, kidneys, stomach and blood vessels. It also reduces self-control and
impairs judgement. Excessive alcohol consumption causes liver damage.
Drugs: Narcotic or psychotropic drugs are those that causes insensible conditions in human
beings, for example, morphine, cocaine, opium, etc. These drugs adversely affect nervous
system and other organs of the body. They may also cause heart and respiratory diseases.
Most of them are highly addictive in nature and thus are hard to leave.
Bacterial Diseases