EMILIO AGUINALDO COLLEGE

School of Nursing

DRUG STUDY

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: By binding phosphate in the Indicated for the control of - Bloating. Sevelamer hydrochloride is Because sevelamer is not absorbed
Sevelamer gastrointestinal tract and serum phosphorus in adults - bloody, black, or tarry contraindicated in patients into the bloodstream, it is not
decreasing absorption, and children 6 years of age stools. with bowel obstruction. expected to be harmful to a nursing
Brand Name: sevelamer carbonate lowers and older with chronic - fast heartbeat. Sevelamer hydrochloride is baby
the phosphate concentration kidney disease (CKD) on - heartburn. contraindicated in patients
in the serum. When taken dialysis. Starting Dose for - hives, itching, rash. with known
Therapeutic with meals, sevelamer Adult Patients Not Taking a - indigestion. hypersensitivity to
Classification: lowers both serum Phosphate Binder. - irritation. sevelamer hydrochloride
Phosphate Binders phosphate and parathyroid - joint pain, stiffness, or
hormone, but does not swelling.
Dosage: increase serum calcium.
800mg

Route:
PO

Frequency:
TID
 EMILIO AGUINALDO COLLEGE
School of Nursing

DRUG STUDY

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: Following ingestion, the Alpha Ketoanalogue is a - Hypercalcemia Hypercalcaemia, disturbed 1. Assess electrolyte levels
Ketoanalouges ketoanalogues are nutritional supplement amino acid metabolism. In 2.Explain therapeutic value of drug
transaminated by taking indicated to improve kidney case of hereditary 3. Assess allergy to the drug
Brand Name: nitrogen from non-essential health in patients diagnosed phenylketonuria it has to be 4.Caution patient of the different side
amino acids, thereby with chronic kidney disease taken into account that effects
decreasing the formation of by decreasing uremic toxins, Ketoanalogues + Essential 5. Assess vital signs
Therapeutic urea by re- using the amino reducing proteinuria, Amino Acids contains 6. Proper preparation of the drugs.
Classification: group. The levels of delaying the onset of dialysis phenylalanine.
Nutritional accumulating uremic toxins treatment and improving
Supplements are decreased. Keto acids metabolism.
do not elicit hyperfiltration
Dosage: of residual nephrons.
600mg

Route:
PO

Frequency:
TID
 EMILIO AGUINALDO COLLEGE
School of Nursing

DRUG STUDY

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: Digoxin induces an Digoxin is indicated in the - Feeling dizzy. Digoxin is contraindicated Nursing considerations include
Digoxin increase in intracellular following conditions: - Feeling or being sick (nausea in the following conditions: educating patients about potential side
sodium that will drive an 1) For the treatment of mild or vomiting) effects and interactions with other
Brand Name: influx of calcium in the to moderate heart failure in - Diarrhoea. - Acute myocardial drugs. Nurses will also need to
Lanoxin heart and cause an increase adult patients. - Changes in your vision infarction. monitor, or educate the patient to
in contractility. Cardiac 2) To increase myocardial (including blurred vision and - Hypersensitivity to monitor pulse, blood pressure, weight,
Therapeutic output increases with a contraction in children not being able to look at bright the drug. urine output, electrolyte levels, and
Classification: subsequent decrease in diagnosed with heart failure. light) - Ventricular digoxin concentrations in the blood.
Cardiac Glycoside ventricular filling pressures. 3) To maintain control - Skin rashes. fibrillation.
ventricular rate in adult - Myocarditis.
Dosage: patients diagnosed with - Hypomagnesemia.
250mg chronic atrial fibrillation. - Hypokalemia.
- Wolf-Parkinson-
Route: White syndrome
PO

Frequency:
3x/wk

DRUG STUDY
 EMILIO AGUINALDO COLLEGE
School of Nursing

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: Omeprazole effectively inhibits Omeprazole is a proton-pump • Headache Omeprazole is contraindicated in Be sure that your patient knows they must
Omeprazole gastric secretion by inhibiting the inhibitor used to manage and treat • Nausea patients with a history of swallow the capsules hole and they should
gastric H+, K+-ATPase. This several conditions, including hypersensitivity to the drug or any take 30, 60 minutes prior to eating the patient
enzyme is responsible for gastric uncomplicated heartburn, peptic • Vomiting excipients from the dosage form should most definitely report any black or
Brand Name: acid production and is located in ulcer disease, gastrointestinal • Diarrhea tarry stools to their provider
the secretory membranes of reflux disease, Zollinger-Ellison
parietal cells. syndrome, multiple endocrine
adenomas, systemic mastocytosis,
Therapeutic erosive esophagitis, gastric ulcers,
Classification: and helicobacterpylori
Proton Pump Inhibitors
(PPIs)

Dosage:
40mg

Route:
PO

Frequency:
OD

DRUG STUDY
 EMILIO AGUINALDO COLLEGE
School of Nursing

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: It works by non- Febuxostat is indicated for - Liver function - azathioprine. Assess joints affected by gout, and
Febuxostat competitively blocking the the chronic management of abnormalities febuxostat monitor pain and other variables
molybdenum pterin center, hyperuricemia in adult - Dizziness increases levels of (range of motion, muscle strength) to
Brand Name: which is the active site of patients with gout who have - Arthralgia azathioprine by document whether this drug is
xanthine oxidase. Xanthine an inadequate response to a - Nausea decreasing successful in helping manage the
oxidase is needed to oxidize maximally titrated dose of - Rash. metabolism. patient's gout. Report any increased
Therapeutic successively hypoxanthine allopurinol, who are - didanosine. pain in joints (arthralgia) or gout
Classification: and xanthine to uric acid. intolerant to allopurinol, or febuxostat will flare-ups that might be related to drug
Xanthine Oxidase Thus, febuxostat inhibits for whom treatment with increase the level treatment.
Inhibitors. xanthine oxidase, thereby allopurinol is not advisable. or effect of
reducing production of uric didanosine by
Dosage: acid. decreasing
40mg metabolism.
- mercaptopurine.
Route: febuxostat
PO increases levels of
mercaptopurine by
Frequency: decreasing
OD metabolism.
- theophylline

DRUG STUDY
 EMILIO AGUINALDO COLLEGE
School of Nursing

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: Iron combines with It is used for the treatment of - Nausea Before taking this • May cause seizures, hypotension,
Ferrous Sulfate + porphyrin and globin chains folic acid deficiency in - Diarrhea medication, tell your doctor constipation, epigastric pain, diarrhea,
Folic to form hemoglobin, which women of child-bearing - Black stools or pharmacist your medical skin. staining, anaphylaxis. • Assess
is critical for oxygen potential and pregnant - Stomach pain history, especially of: iron nutritional status, bowel function.
Brand Name: delivery from the lungs to women. It is also used for - Dark urine overload disorder (such as • Monitor hemoglobin, hematocrit,
other tissues. Iron the treatment of folate- - Fever hemochromatosis, iron levels.
deficiency causes a deficient megablastic anemia - Not hungry hemosiderosis), use/abuse
Therapeutic microcytic anemia due to and iron-deficiency anemia. of alcohol, liver problems,
Classification: the formation of small stomach/intestinal problems
Oral Iron Bivalent erythrocytes with (such as ulcer, colitis).
Preparation insufficient hemoglobin.

Dosage:
1 tab

Route:
PO

Frequency:
TID

DRUG STUDY
 EMILIO AGUINALDO COLLEGE
School of Nursing

DRUG NAME MECHANISM OF INDICATIONS ADVERSE EFFECTS CONTRAINDICATIONS NURSING CONSIDERATIONS

ACTION
Generic Name: Losartan and its principal Losartan is FDA approved • Feeling dizzy. Hypersensitivity to Losartan, be sure while the patient is
Losartan active metabolite block the for the treatment of several • Headaches. Make sure you drug/class/component. on Losartan, you assess their blood
vasoconstrictor and medical conditions, which rest, and drink plenty of fluids. Caution if renal artery pressure, their heart rate, and also
Brand Name: aldosterone-secreting include the following: • Feeling sick (nausea) stenosis, renal impairment their fluid levels monitor daily
effects of angiotensin II by hypertension, diabetic • Being sick (vomiting) or hepatic impairment. weights in patients who have
selectively blocking the nephropathy. ARBs are • Diarrhoea. Caution if volume congestive heart failure. Also renal
Therapeutic binding of angiotensin II to known to be renoprotective • Pain in your joints or depletion, hyponatremia or and liver labs should be monitored
Classification: the AT1 receptor found in in type 2 diabetes mellitus. muscles. severe CHF. while on Losartan.
angiotensin receptor many tissues, (e.g., vascular In hypertension with left
blockers (ARBs) smooth muscle, adrenal ventricular hypertrophy,
gland). losartan inhibits angiotensin
Dosage: II-induced cardiac
5mg remodeling.

Route:
PO

Frequency:
OD AM