Republic of the Philippines

Pamantasan ng Cabuyao
(University of Cabuyao)
COLLEGE OF HEALTH AND ALLIED SCIENCES
Katapatan Mutual Homes, Brgy. Banay-banay, City of Cabuyao, Laguna 4025

BACHELOR OF SCIENCE IN NURSING

PARAGUA, JOERIN B.
3BSN-B

NAME OF MECHANISM OF INDICATION CONTRAINDICA SIDE EFFECTS NURSING

DRUG ACTION TION CONSIDERATE
Generic Name: The commonly Donepezil is Donepezil is  Allergic reactions Assessment & Drug
Donepezil accepted cholinergic primarily used for contraindicated —skin rash, itching, Effects
hypothesis proposes the treatment of for patients with a hives, swelling of the
Brand Name: that a portion of the dementia known face, lips, tongue, or  Monitor therapeutic
Aricept, Aricept cognitive and behavioral associated with hypersensitivity to throat. effectiveness:
Evess decline associated with Alzheimer donepezil Improvement as
 Peptic ulcer—
Alzheimer's are the disease and has hydrochloride or noted on the
Classification: result of decreased FDA approval for piperidine burning stomach
Alzheimer's
Cholinesterase cholinergic transmission use in mild, derivatives. pain, loss of
Disease
Inhibitors in the central nervous moderate, and Donepezil and other appetite, bloating, Assessment Scale.
system. Donepezil severe stages of cholinomimetic burping, heartburn,  Monitor closely for
Dosage: selectively and the disease. agents have the nausea, vomiting S&S of GI
10mg reversibly inhibits the potential to trigger  Seizures ulceration and
acetylcholinesterase seizures. Therefore,  Slow heartbeat— bleeding, especially
Route: enzyme, which normally clinicians should be dizziness, feeling with concurrent use
Oral route breaks down cautious when faint or lightheaded, of NSAIDS.
acetylcholine. The main prescribing it to  Monitor carefully
confusion, trouble
Frequency: pharmacological actions patients with a history patients with a
breathing, unusual
5 milligrams of this drug are believed of seizure disorder. history of asthma or
(mg) taken at to occur as the result of weakness or fatigue
obstructive
bedtime. Your this enzyme inhibition,  Stomach bleeding
pulmonary disease.
doctor may enhancing cholinergic —bloody or black,
 Monitor
increase your transmission, which tar-like stools,
cardiovascular
dose as needed. relieves the symptoms vomiting blood or status; drug may
However, the of Alzheimer's brown material that
 Republic of the Philippines
Pamantasan ng Cabuyao
(University of Cabuyao)
COLLEGE OF HEALTH AND ALLIED SCIENCES
Katapatan Mutual Homes, Brgy. Banay-banay, City of Cabuyao, Laguna 4025

BACHELOR OF SCIENCE IN NURSING

dose usually is dementia. In addition looks like coffee have vagotonic
not more than 10 to the above, other grounds effect on the heart,
mg per day mechanisms of  Trouble passing causing
urine bradycardia,
action of donepezil
especially in
are possible, presence of
including the conduction
opposition of abnormalities.
glutamate-induced
excitatory Patient & Family
transmission via Education
downregulation of
 Exercise caution.
NMDA receptors
Fainting episodes
and the regulation related to slowing
of amyloid proteins, the heart rate may
which have occur.
demonstrated  Report immediately
significant effects to physician any
on the disease S&S of GI
ulceration or
process of
bleeding (e.g.,
Alzheimer's. Other "coffee-grounds"
possible targets for emesis, tarry
donepezil may also stools, epigastric
include the inhibition pain).
various inflammatory
signaling pathways,
exerting neuroprotective
effects.