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    Gumboro Disease: Daissy Vanessa Diaz Guerrero - 542874

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    Ana Maria Vargas Ruiz
    Gumboro disease, also known as infectious bursal disease (IBD), is caused by a birnavirus that infects chickens. It was first observed and named after the town of Gumboro, Delaware, USA. The virus infects the bursa of Fabricius, causing immunosuppression. Clinical signs vary but include high mortality rates in young chickens. Diagnosis is based on clinical signs and histopathology. There is no treatment, but vaccination is used for prevention and control of the disease.

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    Gumboro Disease: Daissy Vanessa Diaz Guerrero - 542874

    Uploaded by

    Ana Maria Vargas Ruiz
    68 views10 pages
    Gumboro disease, also known as infectious bursal disease (IBD), is caused by a birnavirus that infects chickens. It was first observed and named after the town of Gumboro, Delaware, USA. The virus infects the bursa of Fabricius, causing immunosuppression. Clinical signs vary but include high mortality rates in young chickens. Diagnosis is based on clinical signs and histopathology. There is no treatment, but vaccination is used for prevention and control of the disease.

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    Gumboro disease

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    Gumboro disease, also known as infectious bursal disease (IBD), is caused by a birnavirus that infects chickens. It was first observed and named after the town of Gumboro, Delaware, USA. The virus infects the bursa of Fabricius, causing immunosuppression. Clinical signs vary but include high mortality rates in young chickens. Diagnosis is based on clinical signs and histopathology. There is no treatment, but vaccination is used for prevention and control of the disease.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    68 views10 pages

    Gumboro Disease: Daissy Vanessa Diaz Guerrero - 542874

    Uploaded by

    Ana Maria Vargas Ruiz
    Gumboro disease, also known as infectious bursal disease (IBD), is caused by a birnavirus that infects chickens. It was first observed and named after the town of Gumboro, Delaware, USA. The virus infects the bursa of Fabricius, causing immunosuppression. Clinical signs vary but include high mortality rates in young chickens. Diagnosis is based on clinical signs and histopathology. There is no treatment, but vaccination is used for prevention and control of the disease.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 10

    Gumboro disease

    Daissy Vanessa Diaz Guerrero - 542874


    Introduction
    Also known as:
    • Infectious bursal disease (IBD)

    The first report of a specific disease affecting


    the bursa of Fabricius in chickens was made
    by Cosgrove in 1962.

    The first cases were observed in the area of


    Gumboro, in Delaware (United States of
    America [USA]).
    Etiology
    Birnavirus (Birnaviridae) Incubation period: 2-3 days.

    In infected flocks, morbidity is high,


    with up to 100% serological
    conversion, after infection, whilst
    mortality is variable.

    Mortality commences on the third


    day of infection

    the surviving chickens recover a


    state of apparent health after 5-7
    days.

    Clinical presentations:
    • Classical form.
    Serotype 1 • immunosuppressive form (variant).
    • Acute form (very virulent).

    Infect chickens and turkeys but have not


    caused clinical disease or
    Serotype 2 immunosuppression in these hosts.
    Transmission

    Direct and indirect contact with


    infected birds, often through
    exposure to feces.

    Feed, water, litter/bedding


    material, and equipment can
    become contaminated with the
    virus.

    Disease severity depends on the


    age and breed sensitivity of the
    infected birds, the virulence of the
    strain, and the degree of passive
    immunity.

    IBDV does not infect humans and


    is therefore not a zoonosis
    Signs and symptoms
    Clinical signs of IBD vary considerably from one farm,
    region, country or even continent to another.
    Pathological and pathognomonic lesions

    A B
    • A. and B. Atrophic
    bursa of Fabricius
    • C. Feathers around
    the vent are
    Fig. C Fig. D stained with faeces
    containing. plenty

    C D of urates.
    • D. Hemorrhages in
    the pectoral, thigh
    and abdominal
    muscle.
    Diagnostic

    Clinical signs. Differential diagnoses:


    • Avian coccidiosis.
    • Newcastle disease (visceral
    forms).
    Histopathology. • Chicken infectious anaemia.
    • Mycotoxicoses.
    • Nephropathogenic forms of
    Polymerase chain infectious bronchitis.
    reaction (PCR)  • Marek's disease.
    Treatment and prevention
    No treatment is available.

    Attenuated live virus vaccines and oil- Success of vaccination depends on the
    emulsion inactivated virus vaccines are used choice of the vaccine strain and on the
    against IBDV. vaccination schedule.

    Prevention of IBD necessitates hygiene


    measures and medical prophylaxis.
    References
    • Li, Jiaxin, and Shijun J. Zheng. Role of MicroRNAs in Host Defense against Infectious Bursal Disease Virus (IBDV)
    Infection: A Hidden Front Line Viruses (2020).
    • Orakpoghenor, Ochuko, Sunday B. Oladele, and Paul A. Abdu. Infectious Bursal Disease: Transmission,
    Pathogenesis, Pathology and Control-An Overview World's Poultry Science Journal (2020).
    • Fan, Linjin, et al. Novel variants of infectious bursal disease virus can severely damage the bursa of fabricius of
    immunized chickens Veterinary Microbiology (2020).
    • N. Eterradossi and Y.M. Saif Infectious Bursal Disease. Swayne DE, ed. Wiley Blackwell (2020).
    • Dey, Sohini, et al. Infectious bursal disease virus in chickens: prevalence, impact, and management strategies
    Veterinary Medicine: Research and Reports (2019).
    • Stoute, Simone T., et al. Molecular epidemiology of endemic and very virulent infectious bursal disease virus
    genogroups in backyard chickens in California, 2009–2017 Journal of Veterinary Diagnostic Investigation (2019).
    • Category: Gumboro Disease (IBD) Pictures FieldCaseStudy.com (2017).
    • Prandini F, Simon B, Jung A, Pöppel M, Lemiere S, Rautenschlein S.. Comparison of infectious bursal disease
    (IBD) live vaccines and a HVT-IBD vector vaccine and their effects on the immune system of commercial layer
    pullets. Avian Pathology (2016).
    • Infectious Bursal Disease and IBDV. Ohio State University (2016).
    • Washington Animal Disease Diagnostic Lab Infectious Bursal Disease. Washington State University College of
    Veterinary Medicine (2015).
    Gracias

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