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Alzheimer

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ALZHEIMER’S DISEASE

INTRODUCTION TO
ALZHEIMER’S DISEASE
ALZHEIMER’S DISEASE IS A BRAIN DISORDER THAT SLOWLY
DESTROYS MEMORY AND THINKING SKILLS
AND,EVENTUALLY, THE ABILITY TO CARRY OUT THE
SIMPLEST TASKS. THE DISEASE IS NAMED AFTER DR.ALOIS
ALZHEIMER . IN 1906 ,DR.ALZHEIMER NOTICED CHANGES IN
THE BRAIN TISSUE OF A WOMAN WHO HAD DIED OF AN
UNUSUAL MENTAL ILLNESS.
ALZHEIMER ‘S DISEASE

EXPERTS SUGGEST THAT MORE THAN 6 MILLION AMERICANS AGE 65


AND OLDER MAY HAVE ALZHEIMER’S . MANY MORE UNDER AGE 65
CAN ALSO HAVE THIS DISEASE.
CHARACTERESTICS OF ALZHEIMER’S DISEASE
CHARACTERISTICS OF ALZHEIMER’S DISEASE

MEMORY PROBLEMS ARE TYPICALLY ONE OF THE FIRST SIGNS OF


ALZHEIMER’S. A DECLINE IN OTHER ASPECTS OF THINKING ,SUCH
AS FINDING THE RIGHT WORDS.MILD COGNITIVE IMPAIRMENT IS
A CONDITION THAT CAN BE AN EARLY SIGN OF ALZHEIMER’S.
PEOPLE WITH ALZHEIMER’S HAVE TROUBLE DOING EVERYDAY
THINGS. THEY MAY ASK SAME QUESTION AGAIN AND AGAIN AND
MAY FIND SIMPLE THINGS CONFUSING.
CAUSES OF ALZHEIMER’S DISEASE

ALZHEIMER ‘S DISEASE IS THOUGHT TO BE CAUSED BY THE ABNORMAL BUILD UP


OF PROTEINS IN AND AROUND BRAIN CELLS.
ONE OF THE PROTEINS INVOLVED IS CALLED AMYLOID ,DEPOSITS OF WHICH
FORM PLAQUES AROUND BRAIN CELLS .
THE OTHER PROTEIN IS CALLED TAU ,DEPOSITS OF WHICH FORM TANGLES
WITHIN BRAIN CELLS .AS BRAIN CELLS BECOME AFFECTED ,THERE’S ALSO A
DECREASE IN CHEMICAL MESSENGERS INVOLVED IN SENDING MESSAGES, OR
SIGNALS.
CAUSES
CAUSES

FAMILY HISTORY

IN FEW FAMILIES, ALZHEIMER’S DISEASE IS CAUSED BY


INHERITANCE OF A SINGLE GENE AND THE RISKS OF THE
CONDITION BEING PASSED ON ARE MUCH HIGHER
SYMPTOMS OF ALZHEIMER’S DISEASE

1. MEMORY LOSS THAT DISRUPTS DAILY LIFE


ONE OF THE MOST COMMON SYMPTOMS IS FORGETTING THE RECENTLY LEARNED INFORMATION.
FORGETTING ABOUT DATES,DAY ETC.
2. CHALLENGES IN PLANNING OR SOLVING PROBLEMS
HAVING DIFFICULTY IN KEEPING TRACK OF MONTHLY BILLS.
3. PROBLEM IN THINKING AND REASONING
ALZHEIMER’S CAUSES A DECLINE IN THE ABILITY TO MAKE REASONABLE DECISIONS. FOR
EXAMPLE A PERSON WITH ALZHEIMER’S DISEASE MAY WEAR CLOTHES INAPPROPRIATE FOR
WEATHER.
SYMPTOMS OF ALZHEIMER’S DISEASE
4. DIFFICULTY IN PERFORMING FAMILIAR TASKS
ONCE ROUTINE ACTIVITIES THAT REQUIRE SEQUENTIAL STEPS SUCH AS COOKING OR
PLAYING A FAVOURITE GAME BECOMES A STRUGGLE FOR THEM

5. CHANGES IN PERSONALITY AND BEHAVIOUR


• DEPRESSION
• APATHY
• MOOD SWINGS

• LOSS OF INHIBITIONS
• HALLUCINATING
• FAILING IN RECOGNIZING CLOSED ONES
• CHANGES IN SLEEPING HABITS
FAILING IN RECOGNIZING CLOSED ONES
STAGES OF ALZHEIMER’S DISEASE

STAGE 1: BEFORE SYMPTOMS APPEAR


STAGE 2: BASIC FORGETFULNESS
STAGE 3: NOTICEABLE MEMORY DIFFICULTIES
IN THIS STAGE THERE IS TROUBLE IN REMEMBERING RECENTLY READ MATERIAL
STAGE 4 : MORE THAN MEMORY LOSS
IN THIS STAGE THERE IS A CONFUSION ABOUT WHAT DAY IT IS AND WHERE THEY
ARE
STAGES OF ALZHEIMER’S DISEASE

STAGE 5: DECREASED INDEPENDENCE


EMOTIONAL CHANGES ARE COMMON IN THIS STAGE INCLUDING HALLUCINATIONS AND
DELUSIONS
STAGE 6: SEVERE SYMPTOMS
COMMUNICATION MAY BECOME DIFFICULT DURING THIS STAGE.
STAGE 7: LACK OF PHYSICAL CONTROL
THE BODY OF THE PATIENT BEGINS TO SHUT DOWN AND CAN CAUSE SEVERE MENTAL
PHYSICAL IMPAIRMENT. BODY BECOMES VULNERABLE TO VARIOUS OTHER DISEASES.
CURE TO ALZHEIMER’S DISEASE

TREATING THE SYMPTOMS OF ALZHEIMER’S CAN PROVIDE PEOPLE WITH


COMFORT DIGNITY ,AND INDEPENDENCE FOR A LONGER PERIOD OF TIME .
GALANTAMINE ,DONEPEZIL ARE PRESCRIBED FOR
MILD TO MODERATE ALZHEIMER’S SYMPTOMS. THESE DRUGS MAY HELP REDUCE
OR CONTROL SOME COGNITIVE AND BEHAVIORAL SYMPTOMS.
ADACANUMAB IS THE ONLY DISEASE MODIFYING MEDICATION CURRENTLY
APPROVED TO TREAT ALZHEIMER’S. THIS MEDICATION IS A HUMAN ANTIBODY
THAT TARGETS THE PROTEIN BETA AMYLOID AND HELPS TO REDUCE AMYLOID
PLAQUES WHICH ARE BRAIN LESSONS ASSOCIATED WITH ALZHEIMER’S.
TREATMENT FOR MODERATE TO SEVERE
ALZHEIMER’S

A MEDICATION KNOWN AS MEMANTINE AN N –METHYLE D- ASPARTATE


ANTAGONIST IS PRESCRIBED TO CURE SEVERE ALZHEIMER’S DISEASE. THIS
DRUG’S MAIN EFFECT IS TO DECREASE SYMPTOMS ,WHICH WOULD ENABLE
PEOPLE TO MAINTAIN CERTAIN DAILY FUNCTIONS. MEMANTINE
MAY HELP THE PERSON TO USE BATHROOM INDEPENDENTLY.
MEMANTINE IS BELIEVED TO WORK BY REGULATING GLUTAMATE ,AN IMPORTANT
BRAIN CHEMICAL
STILL ALICE A 2014 FILM BASED ON
ALZHEIMER’S DISEASE
STILL ALICE

STILL ALICE IS AN ENLIGHTENING MOVIE WHICH EXPLORERS THE HARSH


REALITY A PERSON FROM BOTH THE PHYSICAL AND EMOTIONAL EFFECTS OF
ALZHEIMER’S DISEASE FULL STOP AS A STORY PROGRESSES ALICE BEGINS
EXPERIENCING GROWING SYMPTOMS OF ALZHEIMER’S. AT FIRST SHE BRUSHES
THE SYMPTOMS OFF AS BEEN ABSENT MINDED .EVENTUALLY THE SYMPTOMS OF
FORGETTING WORDS NAME APPOINTMENTS AND LOCATION LEAD HER SEEK
MEDICAL TREATMENT FROM A NEUROLOGIST. ALICE IS DIAGNOSED WITH AN
INHERITED CASE OF EARLY ONSET ALZHEIMER’S DISEASE.
STILL ALICE

DURING EARLY STAGES OF THE DISEASE COMA ALICE UTILIZES INNOVATIVE


TECHNIQUES TO MAINTAIN FUNCTIONALITY WITHIN HER DAILY LIFE. EVENTUALLY
SHE CANNOT WORK, AND STRUGGLES EVEN TO RECOGNISE HER DAUGHTERS AT
VARIOUS POINTS IN THE FILM. ALICE LOSERS SENSE OF THE PRESENT AS SHE THINKS
SHE IS A CHILD AND BELIEVES SHE IS LIVING IN THE PAST. THIS MOVIE EXCELLENTLY
PORTRAYS THE PSYCHOLOGICAL TORMENT FROM THE THE PATIENTS POINT OF VIEW.
TO ALICE DYING FROM THIS DISEASE IS NOT WHAT FRIGHTENS HER. THE
FRIGHTENING PART TO HER IS LOSING EVERYTHING FROM ONE’S MEMORIES
EXPERIENCES AND PERSONALITY THAT MAKE YOU WHO YOU ARE. ALZHEIMER’S
DISEASE IS A CRUEL ILLNESS AFFECTING THE PATIENT AND THEIR FAMILY WHICH THIS
MOVIE ACCURATELY PORTRAYS.
PRESENTED BY

1. AUSHMITA SAHA
2. HRITIKA DEY
3. OISHANI SINHA
4. RIFAH BARKAT
5. SILVIA GHOSH

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