Lead Toxicity by Amany Rady
Lead Toxicity by Amany Rady
Lead Toxicity by Amany Rady
TOXICITY
By : Amany Rady
Id : 2020002193
OVERVIEW :
-Lead is the most important toxic heavy element
in the environment.
-Lead poisoning occurs when lead builds up in the
body, often over months or years.
Even small amounts of lead can cause serious
health problems.
Children younger than 6 years are especially
vulnerable to lead poisoning, which can severely
affect mental and physical development.
At very high levels, lead poisoning can be fatal.
SOURCE OF TOXICITY :
Sources of Lead toxicity :
1-Lead-Based Paint
2-Contaminated soil
3-Children's Toys and Jewelry
4-Drinking Water
5-Workplace and Hobby Hazards
6-Cosmetics
7- Pottery and ceramic dishes
SYMPTOMS OF TOXICITY :
Initially, lead Poisining can be hard to
detect even people who seem healthy can
have high blood levels of lead.
Signs and symptoms usually don't appear
until dangerous amounts have
accumulated.
Signs and symptoms of lead
poisoning in children include:
1-Learning difficulties
2-Irritability
3-Loss of appetite
4-Weight loss
5- fatigue
6-Abdominal pain
7-Vomiting
8-Constipation
9-Hearing loss
10-seizures
Signs and symptoms in adults might
include:
1-High blood pressure
2-Joint and muscle pain
3-Difficulties with memory or concentration
4-Headache
5-Abdominal pain
6-Mood disorders
7-Reduced sperm count and abnormal sperm
8-Miscarriage, stillbirth or premature birth in
pregnant women
MANAGEMENT OF TOXICITY :
A- Dietary management :
1-Antioxidants 2-Vitamins
B- chelation therapy : is recommended for
children only in cases where blood lead levels are
45 μg/dL or greater.
The drugs used as chelating agents for lead include
DiMercaptoSuccinicAcid (DMSA),
DiMercaptoPropaneSulfonate (DMPS),
Dimercaprol, Penicillamine, and
CalciumDisodiumEthyleneDiamineTetraaceticAci
d (CaNa2EDTA)
PREVENTION OF TOXICITY :
Centers of disease control(CDC) supports
primary and secondary lead exposure
prevention:
1-Primary prevention : is the removal of lead
hazards from the environment before a child is
lead exposed.
2-Secondary prevention : blood lead testing and
follow-up care and referral.
THANK YOU