Immunizations
Immunizations
Immunizations
DURING
PREGNANCY
Immediate goal of
immunization is prevention of
disease in the individual and
eradication of the disease
itself
2 Types of Immunization
Active immunization
Involves administration of
all or part of a microorganism
to elicit an immunologic
response
Passive immunization
Administration of
preformed antibody to a
Live Attenuated Virus
Vaccine
Meales
•Indication during pregnancy
-contraindicated
•Dosing schedule
- Single dose (MMR)
Mumps
•Indication during pregnancy
- contraindicated
•Dosing schedule
- Single dose (MMR)
Rubella
•Indication during pregnancy
- contraindicated
•Dosing schedule
- Single dose (MMR)
Varicella
•Indication during pregnancy
- contraindicated, but no
adverse outcome reported
in pregnancy
•Dosing schedule
- 2 doses needed with 2nd
dose given 4-8 wk after 1st
dose
Inactivated Virus Vaccine
Influenza
•Indication during pregnancy
- All women, regardless of
trimester, who will be
pregnant during the
influenza season
•Dosing schedule
- 1 dose IM every year
Rabies
•Indication during pregnancy
- Indications for prophylaxis
not altered by pregnancy
•Dosing schedule
- To be consulted for
indications, dosage and
route of administration
HepatitiB
•Indication during pregnancy
- Preexposure &
postexposure for women
at risk of infection
•Dosing schedule
- 3 doses series IM at 0, 1,
& 6 month
HepatitisA
•Indication during pregnancy
- Preexposure &
postexposure if at risk
(international travel)
•Dosing schedule
- 2 doses schedule 6
months apart
Inactivated Bacterial
Vaccines
Pneumococcus
•Indication during pregnancy
- Indications not altered by
pregnancy
•Dosing schedule
- 1 dose only; consider
repeat dose in 6 yrs for
high-risk women
Meningococcus
•Indication during pregnancy
- Indications not altered by
pregnancy
•Dosing schedule
- 1 dose
Typhoid
•Indication during pregnancy
- Not recommended
routinely
•Dosing schedule
- Primary: 2 injections > 4
wks apart
- Booster: 1 dose, schedule
not yet determined
Toxoids
Tetanus-diphtheria
•Indication during pregnancy
-lack of primary series or
no booster within past 10
year
•Dosing schedule
- Primary: 2 doses at 1-2
mo interval w/ 3rd dose 6-
12 mo after the 2nd
- Booster: Single dose IM
every 10 year after
Specific Immune Globulins
HepatitisB
•Indication during pregnancy
- Postexposure prophylaxis
•Dosing schedule
- Give along w/ hepatitis
vaccine, then vaccine
alone at 1 & 6 months
Rabies
•Indication during pregnancy
- Postexposure prophylaxis
•Dosing schedule
- Half dose at injury site,
half dose in deltoid
Tetanus