John Harrel

The development of multidrug-resistantAcinetobacter baumanniiis of serious concern in the hospital setting. Here, we report draft genome sequences of 11A. baumanniiisolates that were isolated from a single patient over a 65-day period, during which time the isolates exhibited increased antimicrobial resistance.

In 2012, there was an increase in vancomycin-resistant enterococci (VRE) isolated from the intensive care unit at the University Hospital of Cologne. Using whole-genome sequencing it was possible to establish that bloodstream infections with VRE were not the result of an outbreak or cross infections.

Primary sclerosing cholangitis–IBD (PSC–IBD) is an inflammatory autoimmune hepato–biliary–enteric disease in which it is predicted that gut microbiota have potential pathophysiological effects, relevant to disease initiation and outcome. The recent article by Kummen et al 1 who reported that the gut microbiota in PSC is distinct compared with those from healthy controls and patients with UC without liver disease, is therefore of interest. However, it remains unclear if these alterations in the gut microbiota are a cause or an effect of liver disease, and there remains a challenging task to link dysbiosis with disease pathogenesis, as well as clarify whether faecal microbiota are entirely representative of communities of mucosa-associated bacteria, which might uniquely interact with immune and epithelial cells. Nevertheless Kummen et al notably demonstrated that the Veillonella genus showed a marked increase in PSC–IBD, in comparison with both healthy controls and patients with UC alone. Given interest in the mechanism of lymphocyte tracking between the bowel and liver …

Metagenomic analysis, which involves the sequencing of unenriched DNA from uncultured samples, is probably best known for its use in the analysis of microbes. Here, the method is applied to obtain the sequence of two strains of tuberculosis from a mummified human body.

Metagenomic analysis, which involves the sequencing of unenriched DNA from uncultured samples, is probably best known for its use in the analysis of microbes. Here, the method is applied to obtain the sequence of two strains of tuberculosis from a mummified human body.

San Diego did not easily become the home port of America’s Pacific fleet. It was two decades after the US acquisition of the Philippines, Guam, and Hawai‘i before a combination of imperialist naval strategy, Japanese expansionism, the Great White Fleet, unrest in Mexico and Central America, the completion of the Panama Canal, the Panama-California Exposition, a supportive congressman, and energetic civic leadership coalesced on the issue. Together, these factors led to the establishment of major naval facilities in this southern California city.

u ■ ■■■»■111 ma The views expressed in this paper are those of the author and do not necessarily reflect the views of the Department of Defense or any of its agencies. This document may not be released for open publication until it has been cleared by the appropriate military service or government agency.

The Nisibis War CE 337-363 provides the first campaign analysis of this important conflict between the Roman Empire and the Sassanid Kingdom. Thanks to the availability of primary sources, the Nisibis War lends itself to a detailed analysis, from the strategic conferences of emperors, the field tactics of generals, the heroics of tribunes and the unscrupulous activities of spies, scoundrels, villains, and usurpers. While development of the strategy was simple its implementation was plagued by lack of resources, undermined by the actions of traitors and usurpers and ultimately derailed by King Shapur II and the Royal Persian Army.

San Diego did not easily become the home port of America’s
Pacific fleet. It was two decades after the US acquisition of the Philippines,
Guam, and Hawai‘i before a combination of imperialist naval strategy,
Japanese expansionism, the Great White Fleet, unrest in Mexico and Central
America, the completion of the Panama Canal, the Panama-California
Exposition, a supportive congressman, and energetic civic leadership coalesced
on the issue. Together, these factors led to the establishment of major
naval facilities in this southern California city.

While the development of tanks had largely led to the replacement of cavalry in most armies by
1939, the Soviets retained a strong mounted arm. In the terrain and conditions of the Eastern Front
they were able to play an important role denied them elsewhere. John Harrel shows how the Soviets
developed a doctrine of deep penetration, using cavalry formations to strike into the Axis rear,
disrupting logistics and lines of communication, encircling and isolating units. Interestingly he
shows that this doctrine did not stem from the native cavalry tradition of the steppe but from the
example of the American Civil War. The American approach was copied by the Russians in WWI
and the Russian Civil War, refined by the Soviets in the early stages of World War Two and
perfected during the last two years of the war. The Soviet experience demonstrated that deep
operations (cavalry raids) against enemy rear echelons set the conditions for victory. Although the
last horse-mounted units disappeared in the 1950s, their influence led directly to the formation of the
Operational Manoeuvre Groups that, ironically, faced US forces in the Cold War.

The Nisibis War CE 337-363 provides the first campaign analysis of this important conflict between the Roman Empire and the Sassanid Kingdom. Thanks to the availability of primary sources, the Nisibis War lends itself to a detailed analysis, from the strategic conferences of emperors, the field tactics of generals, the heroics of tribunes and the unscrupulous activities of spies, scoundrels, villains, and usurpers. While development of the strategy was simple its implementation was plagued by lack of resources, undermined by the actions of traitors and usurpers and ultimately derailed by King Shapur II and the Royal Persian Army.