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Pholtan Sebastian

    Pholtan Sebastian

    Coleus hadiensis (Forssk.) A.J.Paton is a horticultural herb that goes to the Lamiaceae family. This plant species has been using to treat diarrhea, skin and digestive disorders, diabetes, and carcinoma in ethnomedicines. This minireview... more
    Coleus hadiensis (Forssk.) A.J.Paton is a horticultural herb that goes to the Lamiaceae family. This plant species has been using to treat diarrhea, skin and digestive disorders, diabetes, and carcinoma in ethnomedicines. This minireview work purposes to analyze, summarize, and document the reported bioactivities of C. hadiensis. Suitable published works were obtained employing the Web of Science, Scopus, PubMed, Semantic Scholar, and ScienceDirect databases from 1900 to December 2020. Hitherto, in vitro level of scientific evidence is the highest level of scientific evidence available for the bioactivities of this plant species. Various parts of C. hadiensis exhibited antioxidant, antibacterial, anti-inflammatory, anticancer, and antimalarial activities in a range of assays. To date, eight bioactive (antimalarial and antioxidant) compounds have been isolated from C. hadiensis. This minireview analyzed, summarized, and documented the reported bioactivities of C. hadiensis. In additi...
    In recent decades diabetes mellitus has become a considerable health problem in countries like Sri Lanka and results in an increasing economic burden hampering the social and economic development of these countries. About 60% to 70% of... more
    In recent decades diabetes mellitus has become a considerable health problem in countries like Sri Lanka and results in an increasing economic burden hampering the social and economic development of these countries. About 60% to 70% of the rural population in Sri Lanka rely on indigenous medicinal systems as their main source for primary health care. Siddha (Tamil) Medicine is one of the four Sri Lankan traditional medicinal systems and it is practised mostly in the eastern and northern provinces of Sri Lanka where the majority of Tamils reside. The foundation of this study is a documentation of plant species recorded in historical and modern Sri Lankan Siddha Medical documents used to treat diabetes. Based on the systematic documentation and analysis of Siddha concepts about diabetes and its signs and preparations used to treat diabetes in Sri Lankan Siddha Medicine, the plant species included in these preparations (excluding globally or very widely used, very well studied species)...
    Background: Thaalankai Oil (~Thaazhankaai Oil) is the oldest and most effective formula in Siddha Medicine and it acts principally by strengthening the immune system. Arthritis is most common problem worldwide , but it has so many causes... more
    Background: Thaalankai Oil (~Thaazhankaai Oil) is the oldest and most effective formula in Siddha Medicine and it acts principally by strengthening the immune system. Arthritis is most common problem worldwide , but it has so many causes and different pathogenesis but whatever it is, Thaalankai oil was successfully curing the disease in practically. The traditional physicians' special formula of Thaalankai oil is containing 22 drugs as thaila dravyas and total ingredients are 27 in number (Constituents of Thaalankai Oil). Methods: Each drug has been taken according to the physician's Siddha Poly Herbal formula. The main ingredient is unripe fruit juice of the Thaalai (Pandanus odoratissimus). It is prescribed from Traditional Siddha Physician Dr. R. Ponniah. This research was an analysis of the ingredients of oil. Results: Explained as, Sweet-22.22%, Pungent-25.9%, Bitter-33.33% in tastes; Cool-33.33%, Hot-62.96% in potency; and Sweet-33.33%, Pungent-62.96% in the bioavailab...
    ABSTRACT