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There is much controversy regarding the use of oral contraceptive pills (OCPs) on cardiometabolic parameters, which is why this longitudinal population-based study was conducted to assess the impact of OCP use and its duration on... more
There is much controversy regarding the use of oral contraceptive pills (OCPs) on cardiometabolic parameters, which is why this longitudinal population-based study was conducted to assess the impact of OCP use and its duration on cardiometabolic factors. Of 5532 reproductive-aged participants of the Tehran lipid and glucose study, 3160 women who met our inclusion criteria were subdivided according to the duration of OCPs consumption into four sub-groups: (1) Non-users; (2) <11 month users; (3) 12-35 month users, and (4) ≥36 month users, and their cardiometabolic parameters were compared. No statistical significant differences were observed between the cardiometabolic parameters of these sub-groups, after further adjustment for confounding factors including age, parity, and education, except for mean low-density lipoprotein-cholesterol which was significantly higher in women who used OCPs for >36 months in comparison to non-OCP users. The odds ratio of hypercholesterolemia was significantly higher in women who used OCPs for >36 months in comparison to non-OCP users; being 1.5 times higher than non-users (95 % CI 1.01-2.2). Results showed that if used for less than 3 years, OCPs have no cardiometabolic effects.
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There is no consensus regarding the impact of polycystic ovary syndrome (PCOS) and its hormonal profile on sexual function of affected women; majority of data documented are not population based and there is a lack of studies... more
There is no consensus regarding the impact of polycystic ovary syndrome (PCOS) and its hormonal profile on sexual function of affected women; majority of data documented are not population based and there is a lack of studies investigating the association between hormonal profiles with sexual function in women with PCOS. We aimed to compare the sexual function of PCOS women with controls in a population-based study based on their hormonal profiles. In this cross-sectional study, sexual function (using the Female Sexual Function Index (FSFI) questionnaire) and hormonal profiles were determined in 63 PCOS subjects and 216 healthy women (controls); aged 18-45 years. A comparison of PCOS women and controls showed no statistically significant difference in total FSFI and each of its specific domain scores. There were significant positive correlations between dehydroepiandrosterone sulfate and total FSFI, orgasm and satisfaction domains in controls (r=0.156, r=0.206, r=0.275, respectively). No significant correlations between hormonal profiles and FSFI scores were found in the PCOS group, except for prolactin and orgasm (r=-0.250). In conclusion, sexual function did not differ between PCOS women and controls. High levels of androgens in women with PCOS were not associated with an improvement in sexual function.
Research Interests: Pain, Medicine, Iran, Population, Humans, and 14 moreFemale, Orgasm, Clinical Sciences, Polycystic Ovary Syndrome, Adult, Hormone, Sexual Function, IMPOTENCE, Cross Sectional Studies, Personal Satisfaction, Case Control Studies, Surveys and Questionnaires, Polycystic ovary, and dehydroepiandrosterone sulfate
Research Interests: Biotechnology, Cancer, Cell Biology, HR, Medicine, and 15 moreIran, Insulin Resistance, Humans, Diabetes mellitus, DM, Female, BMI, Body Mass Index, Ci, Adult, Dyslipidemia, Fbs, HTN, Cross Sectional Studies, and hazard ratio
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We aimed to compare the ovarian reserve of rats exposed to oral D‐galactose during prenatal and early life with rats exposed to D‐galactose only during the prenatal period. Fifteen female pregnant Wistar rats were randomly divided into... more
We aimed to compare the ovarian reserve of rats exposed to oral D‐galactose during prenatal and early life with rats exposed to D‐galactose only during the prenatal period. Fifteen female pregnant Wistar rats were randomly divided into three groups. The first and second groups were fed a D‐galactose enriched diet (35%) from the third day of pregnancy to parturition (PP) and the third day to the end of lactation (PL), respectively. The control group (C group) was fed a standard diet. The study population was the female offspring of three groups (PP′, PL′, and C′), in which some reproductive factors were examined between 45 and 50 days of age. When compared with the PP′ group, the number of primordial follicles was significantly higher in the PL′ group at PND 45–50 (40 vs. 30; p = .01); however, the antimullerian hormone level was significantly reduced in the PL′ group versus control group (−2.2, 95% confidence interval [CI]: −2.83, −1.53 ng/ml p = .000), and follicle‐stimulating hormone level significantly increased in PP′ group versus control (4.5 mIU/ml, 95% CI: 1.40–7.62, p = .005). There was no significant difference in leukocyte infiltration or antiovarian antibody among the groups. Continued exposure to D‐galactose during the lactation period inhibits the primordial follicle loss in rats in terms of producing fewer atretic follicles.
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Background: Infertility has a varied impact on multiple dimensions of health and functioning of women. Objective: We aimed to identify the burden of infertility and its influencing factors based on a population based study conducted in... more
Background: Infertility has a varied impact on multiple dimensions of health and functioning of women. Objective: We aimed to identify the burden of infertility and its influencing factors based on a population based study conducted in four provinces of Iran. Materials and methods: A sample of 1126 women, aged 18-45 years, was selected using the multi stage, stratified probability sampling procedure; those met the eligibility criteria were invited for further comprehensive interview. This study used the definition of infertility proposed by World Health Organization "the woman has never conceived despite cohabitation and exposure to pregnancy for a period of 1 year". Results : The overall prevalence of lifetime infertility and current primary infertility were 21.1% (95% CI: 18.4- 23.8) and 6.4% (95% CI: 4.8-8) respectively. The probability of first pregnancy at the end of 2 years of marriage was 94% for all ever-married women. Infertility were observed as significantly higher among women age 31-35 (OR: 4.6; 95% CI: 1.9-11.5; p=0.001) and women with more than 9 years of education (OR: 2.8; 95% CI: 1.5-3.3; p<0.0001). Conclusion: The necessities of modern living have compelled many women to postpone childbearing to their late reproductive years; however they must be informed of being at risk of infertility with ageing.
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قدمه: اختلالات قاعدگي طيف وسيعي از مشکلات نظير بينظمي قاعدگي، هيپر- و هيپو منوره، پليمنوره و اليگومنوره، ديسمنوره، آمنوره، منوراژي و سندرم پيش از قاعدگي را در بر ميگيرد. هدف اين مطالعه تعيين ميزان شيوع انواع اختلالات قاعدگي و همچنين... more
قدمه: اختلالات قاعدگي طيف وسيعي از مشکلات نظير بينظمي قاعدگي، هيپر- و هيپو منوره، پليمنوره و اليگومنوره، ديسمنوره، آمنوره، منوراژي و سندرم پيش از قاعدگي را در بر ميگيرد. هدف اين مطالعه تعيين ميزان شيوع انواع اختلالات قاعدگي و همچنين تعيين برخي عوامل تأثيرگذار بر بروز اختلالات قاعدگي در ميان زنان ايراني در سنين باروري بود. روش کار: مطالعه حاضر يک مطالعه مقطعي مبتني بر جمعيت بود. افراد شرکت کننده در مطالعه، زنان 45 -18 ساله ايراني بودند که به روش نمونهگيري خوشهاي طبقهبندي شده سهميهاي از چهار استان منتخب کشور انتخاب شدند. يافتهها: تعداد 941 زن واجد شرايط وارد مطالعه شدند. شايعترين اختلالات قاعدگي در زنان ايراني ديسمنوره (5/67%) و سندرم پيش از قاعدگي (9/54%) بود. عوامل زمينهاي نظير سن پايين، ازدواج در سنين بالا، و همچنين تجرد با بروز ديسمنوره ارتباط معنادار داشت (001/0 p < ). شاخص توده بدني بالاو بالا بودن ميزان تحصيلات به ترتيب با احتمال وقوع اليگومنوره و سندرم پيش از قاعدگي رابطه معنادار نشان داد (001/0 p < ). وقوع سن منارک در سنين پايينتر نيز با احتمال وقوع منوراژي ارتباط معنادار داشت. نتيجهگيري: تقريبا يک نفر از هر چهار زن ايراني در سنين باروري حداقل از يکي از اختلالات قاعدگي رنج ميبرد. تغيير سبک زندگي زنان، تشويق آنان به ازدواج در سنين باروري و مشاوره و اطلاعرساني کافي در زمينه اختلالات قاعدگي ميتواند نقش مهمي در کاهش عوارض ثانوي و سوء اين اختلالات داشته باشد.
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Introduction: Men pay less attention to their health status and have worse life styles compared to women. The current study investigates the perceptio nal barriers for health among men. Methods: This is a qualitative study which was... more
Introduction: Men pay less attention to their health status and have worse life styles compared to women. The current study investigates the perceptio nal barriers for health among men. Methods: This is a qualitative study which was conducted usi ng focus group discussion (FGD). 110 men in different age groups were selected. All FGDs wer e audio recorded and transcribed verbatim. Data wer e analyzed manually using constant comparative analys is and open, axial, and selective coding. Conformability and credibility of the data were val id ted. Results: The present study demonstrated that economical con cerns, family issues, lack of social security, environmental problems and not having appropriate g eneral management strategies are the main health barriers that prevent men from thinking of health a s a priority. Content analysis showed that the majo r concern of men was financial, mostly due to unemplo yment. A small number of men who considered health as an important issue, did so to avoid being a burd en ather than thinking of health per se. Conclusion: This study showed the barriers that prevent men fr om thinking of health as a main priority. These findings can assist health policy makers in d esigning appropriate strategies for prevention of d iseases.
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مقدمه: تغييرات فيزيکي و ظاهري زنان مبتلا به سندرم تخمدان پليکيستيک مانند هيرسوتيسم، چاقي، آکنه، کاهش موي سر و نيز پيامدهايي مانند ناباروري ميتواند منجر به کاهش عملکرد جنسي اين افراد شود. در پژوهش حاضر، به بررسي تاثير علايم باليني اين... more
مقدمه: تغييرات فيزيکي و ظاهري زنان مبتلا به سندرم تخمدان پليکيستيک مانند هيرسوتيسم، چاقي، آکنه، کاهش موي سر و نيز پيامدهايي مانند ناباروري ميتواند منجر به کاهش عملکرد جنسي اين افراد شود. در پژوهش حاضر، به بررسي تاثير علايم باليني اين سندرم بر عملکرد جنسي در زنان متاهل ايراني پرداخته شد. مواد و روشها gte vml 1]> !vml]--> !mso]--> !mso]--> !mso & !vml]--> !vml]--> : مطالعهي مقطعي حاضر روي 600 زن متاهل سنين باروري مبتلا به PCOS که به روش نمونهگيري آسان از ميان مراجعين به مطب خصوصي متخصص زنان انتخاب شده بودند، انجام گرفت. آزمودنيها مورد معاينات باليني و اندازهگيريهاي تنسنجي قرار گرفتند. نسخهي فارسي پرسشنامهي عملکرد جنسي زنان، پرسشنامهي حاوي دادههاي آمارنگاري و سابقهي ابتلا به بيماريها، سوابق باروري توسط آزمودنيها تکميل شد. آناليزهاي آماري با استفاده از نرمافزار SPSS نسخهي 15 انجام شد. يافتهها: حدود دو سوم از زنان مبتلا به PCOS اختلال عملکرد جنسي داشتند. يافتهها نشان داد ناباروري تاثيرگذارترين علامت باليني اين سندرم بر عملکرد جنسي زنان مبتلا است. ا...
Research Interests: Infertility and Medicine
ObjectivesThe aim of the study was to investigate the effect of treatment on pregnancy outcomes among women who had fasting plasma glucose (FPG) 5.1-5.6 mmol/l in the first trimester of pregnancy.MethodsWe performed a secondary-analysis... more
ObjectivesThe aim of the study was to investigate the effect of treatment on pregnancy outcomes among women who had fasting plasma glucose (FPG) 5.1-5.6 mmol/l in the first trimester of pregnancy.MethodsWe performed a secondary-analysis of a randomized community non-inferiority trial of gestational diabetes mellitus (GDM) screening. All pregnant women with FPG values range 5.1-5.6 mmol/l in the first trimester of gestation were included in the present study (n=3297) and classified to either the (i) intervention group who received treatment for GDM along with usual prenatal care (n=1,198), (ii) control group who received usual-prenatal-care (n=2,099). Macrosomia/large for gestational age (LGA) and primary cesarean-section (C-S) were considered as primary-outcomes. A modified-Poisson-regression for binary outcome data with a log link function and robust error variance was used to RR (95%CI) for the associations between GDM status and incidence of pregnancy outcomes.ResultsThe mean mat...
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Background: We aimed to investigate the association between kidney stones and polycystic ovarian syndrome (PCOS). Materials and methods: In a cross-sectional study, data from the Tehran Lipid and Glucose Study (TLGS) were used to... more
Background: We aimed to investigate the association between kidney stones and polycystic ovarian syndrome (PCOS). Materials and methods: In a cross-sectional study, data from the Tehran Lipid and Glucose Study (TLGS) were used to investigate the risk of kidney stones in women with Polycystic Ovary Syndrome (PCOS). Four distinct phenotypes of PCOS, as defined by the Rotterdam criteria, were examined in a sample of 520 women and compared to a control group of 1638 eumenorrheic non-hirsute healthy women. Univariate and multivariable logistic regression models were employed for analysis. The four PCOS phenotypes were classified as follows: Phenotype A, characterized by the presence of all three PCOS features (anovulation (OA), hyperandrogenism (HA), and polycystic ovarian morphology on ultrasound (PCOM)); Phenotype B, characterized by the presence of anovulation and hyperandrogenism; Phenotype C, characterized by the presence of hyperandrogenism and polycystic ovarian morphology on ultr...
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Introduction: Premature ovarian insufficiency (POI) affects about 1% of women of reproductive age, with no curative treatment. Several efforts have been made to develop an animal model of POI that mimics all manifestations of this... more
Introduction: Premature ovarian insufficiency (POI) affects about 1% of women of reproductive age, with no curative treatment. Several efforts have been made to develop an animal model of POI that mimics all manifestations of this disease; however, these models are limited due to increased mortality or high toxicity. Overall, well-developed animal models may improve our knowledge of diseases and can be suitable for identifying the underlying mechanisms and detecting the optimal treatment methods. In the present study, we aimed to present a functional rat model of POI, mimicking the clinical manifestations of POI in women. Materials and Methods: This experimental study was performed in two steps. In the first step (induction of the rat POI model), a total of 40 pregnant Wistar rats were randomly divided into four groups. Three experimental groups were fed galactose-enriched diets at days 3-15 of pregnancy (group 1); on the third day of pregnancy until the end of pregnancy (group 2); ...
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<p>p value for log rank = 0.06.</p
Research Interests: Science Policy, Biotechnology, Cancer, Cell Biology, HR, and 9 moreMedicine, Diabetes mellitus, DM, BMI, Body Mass Index, PLoS one, Ci, Fbs, and HTN
The purpose of this paper is to investigate the industrial wage inequalities based on Krugman model. For this, we’ve employed a panel method for 30 Iranian provinces during time period 2003-2007. The estimation results suggest that the... more
The purpose of this paper is to investigate the industrial wage inequalities based on Krugman model. For this, we’ve employed a panel method for 30 Iranian provinces during time period 2003-2007. The estimation results suggest that the new economic geography provides a good description of the spatial structure of wages in the provinces of Iran. Our findings indicate that market size and distance-weighted will have positive relationship with wages. The overall result of this study corroborates the notion of centralization in the Iranian economy. The large wage variations explained by economic geography could cause significant internal migration.
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<p>P value for log rank <0.001.</p
Research Interests: Science Policy, Biotechnology, Cancer, Survival Analysis, Cell Biology, and 10 moreHR, Medicine, Diabetes mellitus, DM, BMI, Body Mass Index, PLoS one, Ci, Fbs, and HTN
Additional file 1 (PDF 400 KB)
قدمه: اختلالات قاعدگي طيف وسيعي از مشکلات نظير بينظمي قاعدگي، هيپر- و هيپو منوره، پليمنوره و اليگومنوره، ديسمنوره، آمنوره، منوراژي و سندرم پيش از قاعدگي را در بر ميگيرد. هدف اين مطالعه تعيين ميزان شيوع انواع اختلالات قاعدگي و همچنين... more
قدمه: اختلالات قاعدگي طيف وسيعي از مشکلات نظير بينظمي قاعدگي، هيپر- و هيپو منوره، پليمنوره و اليگومنوره، ديسمنوره، آمنوره، منوراژي و سندرم پيش از قاعدگي را در بر ميگيرد. هدف اين مطالعه تعيين ميزان شيوع انواع اختلالات قاعدگي و همچنين تعيين برخي عوامل تأثيرگذار بر بروز اختلالات قاعدگي در ميان زنان ايراني در سنين باروري بود. روش کار: مطالعه حاضر يک مطالعه مقطعي مبتني بر جمعيت بود. افراد شرکت کننده در مطالعه، زنان 45 -18 ساله ايراني بودند که به روش نمونهگيري خوشهاي طبقهبندي شده سهميهاي از چهار استان منتخب کشور انتخاب شدند. يافتهها: تعداد 941 زن واجد شرايط وارد مطالعه شدند. شايعترين اختلالات قاعدگي در زنان ايراني ديسمنوره (5/67%) و سندرم پيش از قاعدگي (9/54%) بود. عوامل زمينهاي نظير سن پايين، ازدواج در سنين بالا، و همچنين تجرد با بروز ديسمنوره ارتباط معنادار داشت (001/0 p < ). شاخص توده بدني بالاو بالا بودن ميزان تحصيلات به ترتيب با احتمال وقوع اليگومنوره و سندرم پيش از قاعدگي رابطه معنادار نشان داد (001/0 p < ). وقوع سن منارک در سنين پايينتر نيز با احتمال وقوع منوراژي ا...
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With the change in population policy from birth control toward encouraging birth and population growth in Iran, repeated cesarean deliveries as a main reason of cesarean section are associated with more potential adverse consequences. The... more
With the change in population policy from birth control toward encouraging birth and population growth in Iran, repeated cesarean deliveries as a main reason of cesarean section are associated with more potential adverse consequences. The aim of this research was to explore effective strategies to reduce cesarean delivery rates in Iran. A mixed methodological study was designed and implemented. First, using a qualitative approach, concepts and influencing factors of increased cesarean delivery were explored. Based on the findings of this phase of the study, a questionnaire including the proposed strategies to reduce cesarean delivery was developed. Then in a quantitative phase, the questionnaire was assessed by key informants from across the country and evaluated to obtain more effective strategies to reduce cesarean delivery. Ten participants in the qualitative study included policy makers from the Ministry of Health, obstetricians, midwives and anthropologists. In the next step, 1...
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Background: Embryonic life is critical for the formation of ovaries in mammals, and the intrauterine environment may affect ovarian reserve. Objectives: The present study aimed to investigate the impact of prenatal D-galactose exposure on... more
Background: Embryonic life is critical for the formation of ovaries in mammals, and the intrauterine environment may affect ovarian reserve. Objectives: The present study aimed to investigate the impact of prenatal D-galactose exposure on ovarian reserve in female rat offspring in their later lives. Methods: Ten pregnant Wistar rats were randomly divided into two groups. In one group, rats were fed with 35% D-galactose-enriched food from the third day to the end of pregnancy, and in the other group, rats were fed with a standard diet throughout pregnancy. Female offspring (prenatally galactose-exposed rats and non-exposed control rats) were examined in terms of hormonal levels (anti-Mullerian hormones (AMH), follicle-stimulating hormone (FSH), and estradiol (E2)) and ovarian histology at 45 - 50, 105 - 110, and 180 - 185 days of their age. Results: The number of primordial follicles significantly decreased time-dependently in prenatally galactose-exposed rats compared to controls (P...
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Background There is lack of ideal and comprehensive economic evaluations of various GDM strategies. The aim of this study is to the compare efficacy and cost-effectiveness of five different methods of screening for gestational diabetes... more
Background There is lack of ideal and comprehensive economic evaluations of various GDM strategies. The aim of this study is to the compare efficacy and cost-effectiveness of five different methods of screening for gestational diabetes mellitus (GDM). Methods This study is a randomized community non-inferiority trial among 30,000 pregnant women in five different geographic regions of Iran, who were randomly assigned to one of the five GDM screening methods. All first trimester pregnant women, seeking prenatal care in governmental health care systems, who met our eligibility criteria were enrolled. The criteria suggested by the International-Association-of-Diabetes-in-Pregnancy-Study-Group, the most intensive approach, were used as reference. We used the non-inferiority approach to compare less intensive strategies to the reference one. Along with routine prenatal standard care, all participants were scheduled to have two phases of GDM screening in first and second-trimester of pregn...
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It has been reported that early menarche is associated with higher risk for type 2 diabetes. We aimed to explore the association between age at menarche and risk of type 2 diabetes in a population-based cohort study. For the purpose of... more
It has been reported that early menarche is associated with higher risk for type 2 diabetes. We aimed to explore the association between age at menarche and risk of type 2 diabetes in a population-based cohort study. For the purpose of the present study, 5191 subjects of reproductive age who were participants of the Tehran Lipid and Glucose Study and also met the eligibility criteria were selected. Demographic, lifestyle, reproductive, and anthropometric data as well as risk factors for metabolic diseases were collected. Menarcheal age was categorized into five categories, as <11 years, 11-12 years, 13-14 years, 15-16 years, and >17 years. Diabetes and pre-diabetes were defined according to the American Diabetes Association criteria. Logistic regression analysis was used to assess the risk of the menarcheal age group for type 2 diabetes and pre-diabetes. Of 5625 participants, 673 women had pre-diabetes and 187 had diabetes. Early menarche was associated with higher risk of dia...
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Background Premature ovarian insufficiency (POI) considered as a concerning health issue for women of reproductive age. In this study we aim to estimate the prevalence of POI and assessing the influential factors. Methods Data was... more
Background Premature ovarian insufficiency (POI) considered as a concerning health issue for women of reproductive age. In this study we aim to estimate the prevalence of POI and assessing the influential factors. Methods Data was obtained from Tehran lipid and glucose study (TLGS). All eligible post-menarcheal female participants of the TLGS, ages 20–65, were recruited (n = 6521). Participants were followed for the event of menopause, and age at menopause was recorded. Kaplan Meier analysis was applied to estimate mean and median for age at menopause. Weibull accelerated failure time survival regression model (AFT), was applied to assess influential determinants of POI. Conditional probability approach was used to provide estimation for prevalence of POI. Results In this population-based study, the prevalence of POI (menopause age < 40 years) and early menopause (menopause age < 45 years) were estimated 3.5% and 24.6%, respectively. AFT model showed that in comparison to norm...
Introduction MetS is a group of risk factors that increase the risk of heart diseases, diabetes and, strokes, with a prevalence rate of 13.8% to more than 60.0% in various populations [1-4]. Menopausal transition is considered to be a... more
Introduction MetS is a group of risk factors that increase the risk of heart diseases, diabetes and, strokes, with a prevalence rate of 13.8% to more than 60.0% in various populations [1-4]. Menopausal transition is considered to be a risk factor for MetS, probably due to the decreasing estrogen levels and increasing insulin resistance, secondary to the menopause determinates [3,5,6]. Additionally, postmenopause, as a period of hyperandrogenism due to ovarian failure, is accompanied by increasing levels of LDL and decreased levels of HDL cholesterol, associated with MetS [7,8]. Independent of age, postmenopausal and premenopausal periods have higher triglyceride and lower high-density lipoprotein cholesterol (HDL-C) levels [9]. Some studies [10,11], after age adjustment, showed no significant differences among the mentioned components. Longitudinal studies showed the same results [12,13]. One study in Japan showed that menopause was associated with an increase in the total cholester...
مقدمه: تهیهی نقشهی علمی یکی از راههایی است که میتواند ما را از وضعیت پژوهشهای انجام شده در موضوعی خاص و یا حوزههای مختلف پزشکی آگاه نماید. سندرم تخمدان پلیکیستیک یکی از شایعترین بیماریهای زنان است که موضوع بسیاری از مطالعات علمی... more
مقدمه: تهیهی نقشهی علمی یکی از راههایی است که میتواند ما را از وضعیت پژوهشهای انجام شده در موضوعی خاص و یا حوزههای مختلف پزشکی آگاه نماید. سندرم تخمدان پلیکیستیک یکی از شایعترین بیماریهای زنان است که موضوع بسیاری از مطالعات علمی قرار گرفته است. هدف از این مطالعه، ترسیم و تحلیل نقشهی علمی در زمینهی میزان تولید علم در زمینه سندرم تخمدان پلیکیستیک در ایران با توجه به تعداد مقالات و نویسندگان شاخص و مقایسهی آن با میزان تولید علم، به ویژه در جهان، است. مواد و روشها: این مطالعه از نوع پیمایشی است و با روش علمسنجی صورت گرفته است. جامعهی پژوهش شامل کلیه تولیدات علمی در خصوص سندرم تخمدان پلیکیستیک (PCOS) است که از تاریخ اول ژانویه 2000 تا ژوئیه 2016 در پایگاه استنادی WEB of SCIENCE، نمایه شدهاند. در مجموع، 6598 مقاله در زمینه PCOS چاپ شده است که هم استنادی مقولههای موضوعی با استفاده از تکنیک تحلیل و نرمافزار BIBEXCEL مورد بررسی قرار گرفت. نقشهها با استفاده از نرمافزارهایpajek و VOS VIEWER ترسیم شدند. یافتهها: ایران جزو ده کشور اول پیشتاز در تولیدات علمی در زمینه PCOS ...
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Background: Infertility has a varied impact on multiple dimensions of health and functioning of women. Objective: We aimed to identify the burden of infertility and its influencing factors based on a population based study conducted in... more
Background: Infertility has a varied impact on multiple dimensions of health and functioning of women. Objective: We aimed to identify the burden of infertility and its influencing factors based on a population based study conducted in four provinces of Iran. Materials and Methods: A sample of 1126 women, aged 18-45 years, was selected using the multi stage, stratified probability sampling procedure; those met the eligibility criteria were invited for further comprehensive interview. This study used the definition of infertility proposed by World Health Organization “the woman has never conceived despite cohabitation and exposure to pregnancy for a period of 1 year”. Results : The overall prevalence of lifetime infertility and current primary infertility were 21.1% (95% CI: 18.4- 23.8) and 6.4% (95% CI: 4.8-8) respectively. The probability of first pregnancy at the end of 2 years of marriage was 94% for all ever-married women. Infertility were observed as significantly higher among ...
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Context: Menstrual cycle is considered the fifth vital sign among women. This study aimed to summarize the menstrual disturbances in different endocrine disorders. Evidence Acquisition: In this narrative review, relevant studies (up to... more
Context: Menstrual cycle is considered the fifth vital sign among women. This study aimed to summarize the menstrual disturbances in different endocrine disorders. Evidence Acquisition: In this narrative review, relevant studies (up to December 2019) were searched based on the MeSH keywords diabetes, polycystic ovary syndrome, Cushing’s syndrome, thyroid dysfunction, hyperprolactinemia, menstrual cycle, uterine bleeding, and menstruation. Databases used for searching articles included Google Scholar, Scopus, PubMed, and Web of science for observational, experimental, and review studies. Results: Endocrine disorders trigger the onset of menstrual disturbance across the reproductive lifespan of women. Endocrine glands (pituitary, thyroid, pancreas, adrenal, and ovaries) have a functional role in endocrine regulation of the menstrual cycle. According to available evidence, oligomenorrhea (cycles longer than 35 days) is the most common menstrual disturbance among endocrine disorders (th...
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Background: Further studies are needed to extend our knowledge about the association between male infertility and cardio-metabolic disorders. Objectives: We aimed to assess the association between male infertility and cardiometabolic... more
Background: Further studies are needed to extend our knowledge about the association between male infertility and cardio-metabolic disorders. Objectives: We aimed to assess the association between male infertility and cardiometabolic disturbances using a population-based design. Methods: In total, 1611 participants of the Tehran-Lipid and Glucose-Study (phase III) were categorized into two groups of men with documented male infertility (n = 88) and those with at least one live birth and no history of primary infertility (n = 1523). Logistic regression was applied to explore the association between male infertility and cardiometabolic disturbances, including diabetes mellitus, pre-diabetes, hypertension, metabolic syndrome, dyslipidemia, obesity, central obesity, and chronic kidney disease, following adjustment for age and body mass index (BMI). Results: The unadjusted model revealed a significant association between infertility and hypertension and CKD (OR = 1.8; 95% CI: 1.2, 2.9, P...