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Article
Ore-forming fluid characteristics of Jiaodong-type gold deposits in the North China Craton: constraints from the geochemistry of auriferous pyrite
The Early Cretaceous gold deposits in the North China Craton are known as Jiaodong-type gold deposits. Here, we summarize a quantity of reported (including this study) pyrite trace element, δ34S, and Pb isotope d...
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Article
Can similarity of autistic traits promote neural synchronization?
People with similar levels of autistic traits are reported to exhibit better interactions than those with larger differences in autistic traits. However, whether this “similarity effect” exists at the neural l...
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Article
Open AccessGlobal burden of atrial fibrillation attributable to high body mass index from 1990 to 2021: findings from the Global Burden of Disease Study 2021
To assess the global burden of atrial fibrillation (AF) attributable to high body mass index (BMI) from 1990 to 2021 and analyze its spatiotemporal distribution characteristics.
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Article
Relationship Between Process Parameters and Defects in Laser Powder Bed Fusion Additive Manufacturing of Crack-Sensitive Al–Cu–Mg Alloy
Laser powder bed fusion (L-PBF) is an innovative technique used to manufacture complex and customized parts. However, fabricating crack-sensitive Al–Cu–Mg alloy L-PBF parts with controlled defect levels remain...
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Article
Development and validation of a CT based radiomics nomogram for preoperative prediction of ISUP/WHO grading in renal clear cell carcinoma
Nuclear grading of clear cell renal cell carcinoma (ccRCC) is crucial for its diagnosis and treatment.
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Article
The value of a nomogram model based on CT imaging features in differentiating duodenal gastrointestinal stromal tumors from pancreatic head neuroendocrine tumors
To construct a nomogram model based on multi-slice spiral CT imaging features to predict and differentiate between duodenal gastrointestinal stromal tumors (GISTs) and pancreatic head neuroendocrine tumors (NE...
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Article
Enhancing Dispersion of TiB2 Nanoparticles in Al Composites via Ultrasonic-Assisted Fast Cooling Schemes
Particle agglomeration poses the principal challenge in the solidification of particulate-reinforced metal matrix composites (MMNCs). Here, we present an approach aimed at achieving a uniform dispersing of nan...
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Article
Design of Non-Heat Treatable High Pressure Die Casting Al Alloys: A Review
In recent years, Non-Heat Treatable High Pressure Die Casting Al alloys (NHT-HPDC Al alloys) have been proposed and developed for integrated die casting in the automotive industry. These alloys exhibit excelle...
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Article
Open AccessLenvatinib targets STAT-1 to enhance the M1 polarization of TAMs during hepatocellular carcinoma progression
Lenvatinib, a multitarget kinase inhibitor, has been proven to be effective in the treatment of advanced hepatocellular carcinoma. It has been previously demonstrated that tumour associated macrophages (TAMs) ...
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Article
Open AccessCorrection: Gasdermin E benefits CD8 + T cell mediated anti-immunity through mitochondrial damage to activate cGAS-STING-interferonβ axis in colorectal cancer
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Article
Open AccessGasdermin E benefits CD8+T cell mediated anti-immunity through mitochondrial damage to activate cGAS-STING-interferonβ axis in colorectal cancer
Pyroptosis belongs to a unique type of programmed cell death among which GSDME is reported to exert anti-tumor immunity. However, the underlying mechanisms of how to boost tumor-infiltrating lymphocytes and wh...
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Article
DENS-YOLOv6: a small object detection model for garbage detection on water surface
The study of garbage detection on water surface is of great significance for the development of water surface garbage monitoring and automated water surface garbage salvage. However, in water surface garbage s...
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Article
Experimental study on reactions between alkaline basaltic melt and orthopyroxenes: constraints on the evolution of lithospheric mantle in the North China Craton
The experimental results of the reactions between an alkaline basaltic melt and mantle orthopyroxenes under high-temperature and high-pressure conditions of 1300–1400 °C and 2.0–3.0 GPa using a six-anvil appar...
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Article
Delta-radiomics features for predicting the major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer
To investigate if delta-radiomics features have the potential to predict the major pathological response (MPR) to neoadjuvant chemoimmunotherapy in non-small cell lung cancer (NSCLC) patients.
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Article
Open AccessTransmembrane protein 176B regulates amino acid metabolism through the PI3K-Akt-mTOR signaling pathway and promotes gastric cancer progression
The present study aimed to investigate the expression level, biological function, and underlying mechanism of transmembrane protein 176B (TMEM176B) in gastric cancer (GC).
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Chapter and Conference Paper
OSAL-ND: Open-Set Active Learning for Nucleus Detection
The recent advance of deep learning has shown promising power for nucleus detection that plays an important role in histopathological examination. However, such accurate and reliable deep learning models need ...
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Article
Targeting TLK2 inhibits the progression of gastric cancer by reprogramming amino acid metabolism through the mTOR/ASNS axis
Several recent studies have suggested that TLKs are related to tumor progression. However, the function and mechanism of action of TLK2 in gastric cancer (GC) remain elusive. In this study, TLK2 was found to b...
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Article
Curculigoside attenuates osteoporosis through regulating DNMT1 mediated osteoblast activity
This work aims to study the function of curculigoside in osteoporosis and explore whether DNMT1 is closely involved in osteoblast activity. After OB-6 osteoblasts were treated with hydrogen peroxide (H2O2), a cur...
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Article
Achieving ultrahigh fatigue resistance in AlSi10Mg alloy by additive manufacturing
Since the first discovery of the fatigue phenomenon in the late 1830s, efforts to fight against fatigue failure have continued. Here we report a fatigue resistance phenomenon in nano-TiB2-decorated AlSi10Mg enabl...
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Article
The influence of alkyl groups at ortho-position of amino group on the structure and properties of polyimides
A series of polyimides (PIs) using four kinds of m-phenylenediamine monomers containing different substituent groups at the ortho-position of the amino group was synthesized. Furthermore, these polyimides with va...