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Article
Development of a clinical prognostic model for primary plasma cell leukemia patients treated with novel agents: a multicenter retrospective cohort study
The prognosis of primary plasma cell leukemia (pPCL) is poor, and the relevant prognostic factors are incompletely understood. We aimed to explore the prognostic factors and develop a validated prognostic pred...
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Article
Open AccessHuman cytomegalovirus infection impairs neural differentiation via repressing sterol regulatory element binding protein 2-mediated cholesterol biosynthesis
Congenital human cytomegalovirus (HCMV) infection is a major cause of abnormalities and disorders in the central nervous system (CNS) and/or the peripheral nervous system (PNS). However, the complete pathogene...
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Article
Characterization of a membrane Fcγ receptor in largemouth bass (Micropterus saloumoides) and its response to bacterial challenge
Fc receptors (FcRs), specific to the Fc portion of immunoglobulin (Ig), are required to regulate immune responses against pathogenic infections. However, FcγR is a member of FcRs family, whose structure and fu...
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Article
Open AccessEfficacy and safety of generic pomalidomide plus low-dose dexamethasone in relapsed or refractory multiple myeloma: a multicenter, open-label, single-arm trial
This multicenter, open-label, single-arm trial (ClinicalTrials.gov, NCT05236621) was conducted to confirm the efficacy and safety of generic pomalidomide plus dexamethasone in Chinese patients with relapsed or...
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Chapter
Extended-Release Pre-exposure Prophylaxis and Drug-Resistant HIV
The pharmacologic tail of long-acting cabotegravir (CAB-LA), an injectable pre-exposure prophylaxis (PrEP), allows for months-long intervals between injections, but it may facilitate the emergence of drug-resi...
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Article
Co-recovery of Mn and Fe from pyrolusite and copper slag with hydrometallurgy process: Kinetics and leaching mechanisms
With the shortage of high-quality raw materials and increasingly strict environmental regulations, the recovery of metals from copper slag and pyrolusite has become a research hotspot. A novel method for simul...
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Article
Open AccessAponermin or placebo in combination with thalidomide and dexamethasone in the treatment of relapsed or refractory multiple myeloma (CPT-MM301): a randomised, double-blinded, placebo-controlled, phase 3 trial
Aponermin, a circularly permuted tumor necrosis factor-related apoptosis-inducing ligand, is a potential death receptor 4/5-targeted antitumour candidate. Previous phase 1/2 studies have demonstrated the effic...
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Article
Nitrogen addition regulates the growth of Pinus tabuliformis by changing distribution patterns of endogenous hormones in different organs
A controlled experiment with Pinus tabuliformis Carr Seedlings was conducted to investigate the effect of nitrogen (N) deposition on the growth of plant organs by influencing the distribution of different hormone...
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Article
High expression of HOXC6 predicts a poor prognosis and induces proliferation and inflammation in multiple myeloma cells
Multiple myeloma (MM) is a common blood system malignance accompanied by monoclonal plasma cell hyperplasia. Homeobox C6 (HOXC6) acts as an oncogene in various cancers, but its function on MM is elusive.
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Article
The preliminary exploration of composition origin of garnet-type solid inorganic electrolytes by cluster-plus-glue-atom model
The absence of suitable composition unit model hampered the exploration of composition origin of garnet-type solid inorganic electrolytes (G-SIE), which further hindered the development all solid-state lithium...
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Article
Open AccessThe prognostic value of the MASS in a multi-center cohort of patients with newly diagnosed multiple myeloma
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Article
Fluorescent nanodiamonds as enzyme mimics for protecting astrocytes from oxidative stress in a mouse model of epilepsy
Fluorescent nanodiamonds (FNDs) as promising enzyme mimics have attracted a lot of attention in the field of biomedicine. However, the molecular mechanism of their intrinsic peroxidase-like and antioxidant act...
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Article
Open AccessAssessment of genetic diversity and variety identification based on developed retrotransposon-based insertion polymorphism (RBIP) markers in sweet potato (Ipomoea batatas (L.) Lam.)
Sweet potato, a dicotyledonous and perennial plant, is the third tuber/root crop species behind potato and cassava in terms of production. Long terminal repeat (LTR) retrotransposons are highly abundant in swe...
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Article
Correction to: Human Cytomegalovirus Influences Host circRNA Transcriptions during Productive Infection
The information of affiliation 1 and 3 was incorrect. The information of affiliations should read as given below.
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Article
Characterization of a novel brain cell line from Jian carp (Cyprinus carpio var. Jian)
Jian carp (Cyprinus carpio var. Jian) is an economically important cultured fish in China. Currently, it is facing threats from infectious diseases including koi herpesvirus (KHV). Here, we established a new cell...
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Article
Human Cytomegalovirus Influences Host circRNA Transcriptions during Productive Infection
Human cytomegalovirus (HCMV) is a double-strand DNA virus widely infected in human. Circular RNAs (circRNAs) are non-coding RNAs with most functions of which keep unknown, and the effects of HCMV productive in...
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Article
Open AccessCombination of High Zn Density and Low Phytic Acid for Improving Zn Bioavailability in Rice (Oryza stavia L.) Grain
Zn deficiency is one of the leading public health problems in the world. Staple food crop, such as rice, cannot provide enough Zn to meet the daily dietary requirement because Zn in grain would chelate with ph...
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Chapter and Conference Paper
Mapping Between “Classifications for Mineral Resources and Mineral Reserves (GB/T 17766-2020)” and “United Nations Framework Classification for Resources (UNFC-2019)”
The aim of this paper is to provide the basis for development of the Bridging Document between China National Standard of “Classifications for mineral resources and mineral reserves (GB/T 17766-2020)” and “Uni...
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Article
Open AccessWhich is better for mothers and babies: fresh or frozen-thawed blastocyst transfer?
In recent years, there have been many reports on the pregnancy outcomes of fresh blastocyst transfer (BT) and frozen-thawed BT, but the conclusions are controversial and incomplete. To compare the pregnancy ou...
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Article
Levels of human cytomegalovirus miR-US25-1-5p and miR-UL112-3p in serum extracellular vesicles from infants with HCMV active infection are significantly correlated with liver damage
Human cytomegalovirus (HCMV)–encoded microRNAs (miRNAs) are involved in posttranscriptional regulation of gene expression. Extracellular vesicles (EVs) can incorporate miRNAs. Relationship between HCMV infecti...