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353 Result(s)
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Article
Open AccessDevelopment of a Prediction Model and Corresponding Scoring Table for Postherpetic Neuralgia Using Six Machine Learning Algorithms: A Retrospective Study
Postherpetic neuralgia (PHN), a complication of herpes zoster, significantly impacts the quality of life of affected patients. Research indicates that early intervention for pain can reduce the occurrence or s...
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Open AccessFerroelectric polarization and magnetic structure at domain walls in a multiferroic film
Domain walls affect significantly ferroelectric and magnetic properties of magnetoelectric multiferroics. The stereotype is that the ferroelectric polarization will reduce at the domain walls due to the incomp...
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Open AccessComparative assessment of the capability of machine learning-based radiomic models for predicting omental metastasis in locally advanced gastric cancer
The study aims to investigate the predictive capability of machine learning algorithms for omental metastasis in locally advanced gastric cancer (LAGC) and to compare the performance metrics of various machine...
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Open AccessMembrane protein Bcsdr2 mediates biofilm integrity, hyphal growth and virulence of Botrytis cinerea
Grey mould caused by Botrytis cinerea is a devastating disease responsible for large losses to agricultural production, and B. cinerea is a necrotrophic model fungal plant pathogen. Membrane proteins are importan...
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Open AccessRapidly damping hydrogels engineered through molecular friction
Hydrogels capable of swift mechanical energy dissipation hold promise for a range of applications including impact protection, shock absorption, and enhanced damage resistance. Traditional energy absorption in...
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Article
Open AccessHeterogeneous peer effects of college roommates on academic performance
Understanding how student peers influence learning outcomes is crucial for effective education management in complex social systems. The complexities of peer selection and evolving peer relationships, however,...
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Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis
Regulatory T cells (Tregs) prevent autoimmunity and contribute to cancer progression. They exert contact-dependent inhibition of immune cells through the production of active transforming growth factor-β1 (TGF...
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Open AccessResearch on provincial water resources carrying capacity and coordinated development in China based on combined weighting TOPSIS model
With the continuous development of the economy and society, along with the sustained population growth, the issue of water resources carrying capacity in China has attracted increasing attention. This paper co...
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Open AccessPolar Bloch points in strained ferroelectric films
Topological domain structures have drawn great attention as they have potential applications in future electronic devices. As an important concept linking the quantum and classical magnetism, a magnetic Bloch ...
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Article
Open AccessBiomimetic peroxidase MOF-Fe promotes bone defect repair by inhibiting TfR2 and activating the BMP2 pathway
Large bone defects pose a clinical treatment challenge; inhibiting transferrin receptor 2 (TfR2), which is involved in iron metabolism, can promote osteogenesis. Iron-based metal-organic frameworks (MOF-Fe) pa...
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Open AccessTumor microenvironment reprogramming combined with immunogenic enhancement by nanoemulsions potentiates immunotherapy
The combination of immune checkpoint inhibitors and immunogenic cell death (ICD) inducers has become a promising strategy for the treatment of various cancers. However, its efficacy remains unmet because of th...
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Open AccessThe mitochondria-targeted Kaempferol nanoparticle ameliorates severe acute pancreatitis
Kaempferol (KA), an natural antioxidant of traditional Chinese medicine (TCM), is extensively used as the primary treatment for inflammatory digestive diseases with impaired redox homeostasis. Severe acute pan...
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Assembly Nanoparticle Arrays Decorated with Ultrathin AAO Nanopores for Highly Sensitive SERS Substrate
Surface-enhanced Raman scattering (SERS) is widely employed because it offers quick, microscopic, and traceless detection. This study used high-voltage and low-voltage ultrasonic oscillation to embed gold-silv...
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Article
Effects of Halloysite Nanotubes and Multi-walled Carbon Nanotubes on Kruppel-like Factor 15-Mediated Downstream Events in Mouse Hearts After Intravenous Injection
Halloysite nanotubes (HNTs) are nanomaterials (NMs) derived from natural clays and have been considered as biocompatible NMs for biomedical uses. However, the cardiovascular toxicity of HNTs has not been thoro...
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Open AccessLangerhans cell histiocytosis in children with refractory diarrhoea and hypoalbuminaemia as the initial presentation: two case reports and a literature review
Langerhans cell histiocytosis (LCH) involving the gastrointestinal tract is a rare condition for which clinical experience is limited. We describe the cases of two patients who initially presented with chronic...
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Open AccessHigh-Efficiency Dynamic Scanning Strategy for Powder Bed Fusion by Controlling Temperature Field of the Heat-Affected Zone
Improvement of fabrication efficiency and part performance was the main challenge for the large-scale powder bed fusion (PBF) process. In this study, a dynamic monitoring and feedback system of powder bed temp...
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Azobenzene as a photoswitchable mechanophore
Azobenzene has been widely explored as a photoresponsive element in materials science. Although some studies have investigated the force-induced isomerization of azobenzene, the effect of force on the rupture ...
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Article
Long-term functional maintenance of primary hepatocytes in vitro using macroporous hydrogels engineered through liquid-liquid phase separation
Preserving the functionality of hepatocytes in vitro poses a significant challenge in liver tissue engineering and bioartificial liver, as these cells rapidly lose their metabolic and functional characteristics a...
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Recent Progress in Enzymatic Preparation of Chitooligosaccharides with a Single Degree of Polymerization and Their Potential Applications in the Food Sector
Chitosan oligosaccharides (COS), derived from chitin, have garnered considerable attention owing to their diverse biological activities and potential applications. Previous investigations into the bioactivity ...
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Numerical study of the influence of the atmospheric pressure on the thermal environment in the passenger cabin
The cabin air pressure remains lower than the horizontal atmospheric pressure when the airplane is in flight. Air pressure is one of the parameters that must be taken into consideration while studying the ther...