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Chapter and Conference Paper
FCGA-Former: A Hybrid Factor Space Classification Model for Predicting the Tumor Mutation Burden of Lung Adenocarcinoma
Lung cancer is a malignant tumor with the highest mutation rate in the world, among which non-small cell lung cancer (NSCLC) has a very high mutation rate. In recent years, medical research has found that tumo...
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Article
Open AccessWild rice GL12 synergistically improves grain length and salt tolerance in cultivated rice
The abounding variations in wild rice provided potential reservoirs of beneficial genes for rice breeding. Maintaining stable and high yields under environmental stresses is a long-standing goal of rice breedi...
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Article
Maternal adiposity and perinatal and offspring outcomes: an umbrella review
Maternal adiposity deleteriously affects obstetrical health and has been associated with long-term adverse consequences in offspring. Here we conducted an umbrella review encompassing 194 observational meta-an...
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Article
Polyunsaturated triacylglycerol accumulation mainly attributes to turnover of de novo-synthesized membrane lipids in stress-induced starchless Chlamydomonas
Assembly of PUFA-attached TAGs is intimately correlated to turnover of newly formed membrane lipids in starch-deficient Chlamydomonas exposed to high light and nitrogen stress under air-aerated mixotrophic condit...
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Article
Open AccessEncapsulated lactiplantibacillus plantarum improves Alzheimer’s symptoms in APP/PS1 mice
Alzheimer’s disease (AD) is a neurodegenerative disorder that can result in neurotoxicity and an imbalance in gut microbiota. Probiotics have been shown to play an important role in regulating the gut microbio...
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Article
No Association of Polycystic Ovary Syndrome with Pancreatic Cancer: A Mendelian Randomization Study
Recently, there has been a debate regarding the association between polycystic ovary syndrome (PCOS) and pancreatic cancer (PC). In order to examine the causal relationship between PCOS and PC, we conducted a ...
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Article
Open AccessA sex-oriented analysis concerning skeletal muscle quantity and quality and associations to quality of life in hospitalized patients with cirrhosis
There is a paucity of data regarding sex-oriented analyses of connection between muscle quantity and quality and health-related quality of life (HRQoL), taking into account the pathophysiological differences o...
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Article
Open AccessIsorhapontigenin inhibition of basal muscle-invasive bladder cancer attributed to its downregulation of SNHG1 and DNMT3b
Bladder cancer (BC) is among the most prevalent malignant urothelial tumors globally, yet the prognosis for patients with muscle-invasive bladder cancer (MIBC) remains dismal, with a very poor 5-year survival ...
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Article
Erratum to: Self-enhancing photothermal conversion of 2D Weyl semimetal WTe2 with topological surface states for efficient solar vapor generation
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Article
The earliest evidence for a microblade adaptation in the remote, high altitude regions of the Tibetan Plateau
Microblade assemblages are among the most common prehistoric archaeological materials found on the Tibetan Plateau (TP) and are thought to indicate large scale migration to and settlement of the TP. Few microb...
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Article
Open AccessPredicting the effect of chemicals on fruit using graph neural networks
The neural network method is a type of machine learning that has made significant advances over the past few years in a variety of fields, particularly text, speech, images, videos, etc. In areas where data is...
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Article
Open AccessTumor microenvironment reprogramming combined with immunogenic enhancement by nanoemulsions potentiates immunotherapy
The combination of immune checkpoint inhibitors and immunogenic cell death (ICD) inducers has become a promising strategy for the treatment of various cancers. However, its efficacy remains unmet because of th...
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Article
OptADMET: a web-based tool for substructure modifications to improve ADMET properties of lead compounds
Lead optimization is a crucial step in the drug discovery process, which aims to design potential drug candidates from biologically active hits. During lead optimization, active hits undergo modifications to i...
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Article
Open AccessMALAT1 expression in granulosa cells in PCOS patients with different phenotypes
Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine metabolic disorders. The lncRNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) reportedly can regulate the rep...
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Article
Open AccessDeconvolution at the single-cell level reveals ovarian cell-type-specific transcriptomic changes in PCOS
Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine disorders in females of childbearing age. Various types of ovarian cells work together to maintain normal reproductive function...
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Article
Open AccessWnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer
Oxaliplatin resistance usually leads to therapeutic failure and poor prognosis in colorectal cancer (CRC), while the underlying mechanisms are not yet fully understood. Metabolic reprogramming is strongly link...
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Article
Open AccessPhysical activity trajectory during pregnancy and associations with maternal fatigue using a growth mixture modeling approach
The purpose of this study was to investigate the associations of physical activity trajectories with maternal fatigue. Pregnant women provided objectively assessed physical activity data by Pregnancy Physical ...
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Chapter
Conclusion
UAVs have become increasingly prevalent in various industries and applications, ranging from military and surveillance operations to commercial and humanitarian uses. Efficient and reliable communication is cr...
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Chapter and Conference Paper
Insert Commonsense Knowledge Through Semantics for Dialogue Generation
Language models such as GPT and BART have been widely applied to various language generation tasks, including dialogue generation. While some works have improved the generation performance of these models by i...
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Book
