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Open AccessBlack TiO2-based nanoparticles as Toll-like receptor stimulator delivery system for enhanced photothermal-immunotherapy of pancreatic cancer
The tumor-specific immune responses, essential for removing residual lesions and preventing tumor metastases, can be stimulated by tumor-associated antigens (TAAs) released following photothermal therapy (PTT)...
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Article
Open AccessTumor microenvironment reprogramming combined with immunogenic enhancement by nanoemulsions potentiates immunotherapy
The combination of immune checkpoint inhibitors and immunogenic cell death (ICD) inducers has become a promising strategy for the treatment of various cancers. However, its efficacy remains unmet because of th...
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Article
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led ...
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Article
Open AccessForecasting incidence of infectious diarrhea using random forest in Jiangsu Province, China
Infectious diarrhea can lead to a considerable global disease burden. Thus, the accurate prediction of an infectious diarrhea epidemic is crucial for public health authorities. This study was aimed at developi...
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Article
Open AccessA case-control study on the risk factors for hemorrhagic fever with renal syndrome
Hemorrhagic fever with renal syndrome (HFRS) is an endemic communicable disease in China, accounting for 90% of total reported cases worldwide. In this study, the authors want to investigate the risk factors f...
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Article
Open AccessEpidemiology of infectious diarrhoea and the relationship with etiological and meteorological factors in Jiangsu Province, China
We depicted the epidemiological characteristics of infectious diarrhoea in Jiangsu Province, China. Generalized additive models were employed to evaluate the age-specific effects of etiological and meteorologi...
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Article
Open AccessForecasting incidence of hand, foot and mouth disease using BP neural networks in Jiangsu province, China
Hand, foot and mouth disease (HFMD) is a rising public health problem and has attracted considerable attention worldwide. The purpose of this study was to develop an optimal model with meteorological factors t...