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Resumo: Introdução: O potencial evocado auditivo de tronco encefálico (PEATE) além de determinar o nível mínimo de resposta eletrofisiológica auditiva, auxilia na caracterização do tipo de perda auditiva e na localização topográfica da... more
Resumo: Introdução: O potencial evocado auditivo de tronco encefálico (PEATE) além de determinar o nível mínimo de resposta eletrofisiológica auditiva, auxilia na caracterização do tipo de perda auditiva e na localização topográfica da lesão. Objetivo: Descrever os ...
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Purpose: The purpose of this article was to assess the effectiveness of the Dangerous Decibels (DD) program in students in the short- and medium-term follow-ups (up to 6 months), including an online game. Method: A randomized trial was... more
Purpose: The purpose of this article was to assess the effectiveness of the Dangerous Decibels (DD) program in students in the short- and medium-term follow-ups (up to 6 months), including an online game. Method: A randomized trial was conducted between two interventions (DD and placebo). The research included 58 participants who were divided into two groups: the study group (SG) and the control group. The following phases were developed: intervention (DD or placebo), post–3-month assessment and availability of the online game, and post–6-month assessment. A questionnaire was administered to assess their performance. Overall total scores and category scores were obtained. Results: Improved overall scores were found in the SG in the immediate post-intervention ( p = .004), post–3-month ( p = .022), and post–6-month ( p = .002) questionnaires, as well as the knowledge and behavior categories. Conclusions: The DD program effectively improved the knowledge and behavior of 10- to 12-year-old children regarding noise in the short- and medium-term follow-ups. However, no significant changes were achieved in terms of barriers only by using the program and the online game. Adding a second intervention (the online game) to the program seems to be a good option to maintain the changes achieved with the interactive class.
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Studies have reported compatibility between hearing and electrophysiological thresholds in the auditory brainstem response (ABR) with tone burst stimuli. AIMS: to verify waves I, III, V and their latency times for tone bursts at 500,... more
Studies have reported compatibility between hearing and electrophysiological thresholds in the auditory brainstem response (ABR) with tone burst stimuli. AIMS: to verify waves I, III, V and their latency times for tone bursts at 500, 1000, 2000 and 4000 Hz and at 80 dB HL, and to compare tone burst electrophysiological thresholds with those obtained from audiological and psychoacoustic evaluations. METHODS: audiological, psychoacoustic and electrophysiological evaluations of 40 male and female normal hearing individuals aged between 18 and 40 years were undertaken. RESULTS: only wave V was visualized at 80 dB HL and its latency values decreased with increased frequencies in both genders. At 1000, 2000 and 4000 Hz male subjects presented higher electrophysiological thresholds values than females at all frequencies. At 500, 1000 and 2000 Hz, electrophysiological, hearing, and psychoacoustic thresholds were statistically different in both genders. CONCLUSION: although ABR with tone burst stimulus is clinically applicable, further research is needed to standardize test techniques and results.
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OBJECTIVES The objective of this study was to investigate auditory hypersensitivity in WS and to evaluate hyperacusis through standardized protocols, checking if it can be associated with the absence of acoustic reflexes in people with... more
OBJECTIVES The objective of this study was to investigate auditory hypersensitivity in WS and to evaluate hyperacusis through standardized protocols, checking if it can be associated with the absence of acoustic reflexes in people with WS. METHOD The study was performed in 17 individuals with WS, aged between seven and 17 years old (10 males and seven females), and 17 individuals with typical development age- and gender-matched to individuals with WS. Statistical tests were used to analyze the responses collected with the Loudness Discomfort Level (LDL) test as well as ipsilateral and contralateral reflex responses. RESULTS Auditory hypersensitivity was commonly found. Individuals with WS had phonophobia and were less tolerant to high sound intensity, presenting a reduced discomfort threshold compared to those with typical development. However, hyperacusis was found in 35.29% of individuals with WS and was mild in 50% of cases. There was an association between hyperacusis and acoustic reflex responses, and individuals with absence of the contralateral acoustic reflex were more likely to have hyperacusis. CONCLUSIONS Individuals with WS have a high prevalence of auditory hypersensitivity, with the presence of phonophobia; however, hyperacusis was not as prevalent and may be associated with the absence of contralateral acoustic reflexes.
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Recent studies involving guinea pigs have shown that noise can damage the synapses between the inner hair cells and spiral ganglion neurons, even with normal hearing thresholds—which makes it important to investigate this kind of... more
Recent studies involving guinea pigs have shown that noise can damage the synapses between the inner hair cells and spiral ganglion neurons, even with normal hearing thresholds—which makes it important to investigate this kind of impairment in humans. The aim was to investigate, with multiple audiological assessments, the auditory function of normal hearing workers exposed to occupational noise. Altogether, 60 workers were assessed (30 in the noise-exposure group [NEG], who were exposed to occupational noise, and 30 in the control group [CG], who were not exposed to occupational noise); the workers were matched according to age. The following procedures were used: complete audiological assessment; speech recognition threshold in noise (SRTN); speech in noise (SN) in an acoustic field; gaps-in-noise (GIN); transient evoked otoacoustic emissions (TEOAE) and inhibitory effect of the efferent auditory pathway; auditory brainstem response (ABR); and long-latency auditory evoked potential...
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SummaryLong latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level.Aimto characterize the LLAEP in individuals with and... more
SummaryLong latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level.Aimto characterize the LLAEP in individuals with and without tinnitus exposed to occupational noise.MethodCross-sectional contemporary cohort, prospective study. Sixty subjects exposed to occupational noise, ranging in age from 29 to 50 years underwent LLAEP assessment; 30 of them had tinnitus complaint and 30 did not have tinnitus.Resultswe observed significant statistical difference regarding the mean values of latencies of waves N1 (p<0.001), P2 (p=0.002) and P300 (p=0.039) when we compared individuals with and without tinnitus. In individuals with tinnitus we also noticed a greater number of altered results concerning components N1 (60%) and P2 (66.7%), although only component P2 presented significant statistical difference (p=0.010). For the LLAEP, the latency increase was the only type of alteratio...
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Individuals with Williams Syndrome (WS) have specific auditory characteristics, including hypoacusis and hyperacusis, and music appreciation skills. Little is known about the functionality of the central auditory nervous system (CANS) for... more
Individuals with Williams Syndrome (WS) have specific auditory characteristics, including hypoacusis and hyperacusis, and music appreciation skills. Little is known about the functionality of the central auditory nervous system (CANS) for sound processing in WS. Thus, the objective of the present study was to evaluate the functionality of the CANS in individuals with WS, based on auditory event-related potentials, as far as cognitive and behavioral aspects are concerned. The study was carried out with 17 individuals, seven females and ten males, between seven and 17 years old, with WS, and 17 individuals with typical development matched by sex and chronological age to individuals with WS. None of these individuals had middle ear impairment or hearing loss. The subjects were evaluated for intelligence quotient, loudness discomfort level, and auditory event-related potentials with Tone Burst stimuli, on the oddball paradigm; the parents also answered the MTA-SNAP-IV questionnaire. Hyperacusis was found in six WS individuals and two individuals with typical development. In the present study, WS individuals present longer latency and reduced amplitude for P1, N1, N2 and P3 components. These results, suggesting a delay and hypoactive responses of the CANS in this syndrome, that cannot be related to the cognitive or behavioral aspects of these individuals, but it indicates a cortical immaturity to process acoustic stimuli.
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Background: Mucopolysaccharidosis type II, also known as Hunter syndrome, is a rare X-linked recessive disorder caused by deficiency of the lysosomal enzyme iduronate-2- sulfatase (IDS), leading to progressive accumulation of... more
Background: Mucopolysaccharidosis type II, also known as Hunter syndrome, is a rare X-linked recessive disorder caused by deficiency of the lysosomal enzyme iduronate-2- sulfatase (IDS), leading to progressive accumulation of glycosaminoglycans (GAGs) in several organs. Over the years, Enzyme Replacement Therapy (ERT) has provided significant benefit for patients, retarding natural progression of the disease.Results: We evaluated 17 patients from the same family with a mild form of MPS type II; proband had developed acute decompensated heart failure refractory to clinical measurements at 23 years and needed a rather urgent heart transplant; however, he died from surgery complications shortly after the procedure. Nevertheless, subsequently to his tragic death, 16 affected male relatives were detected after biochemical tests identifying low or absent activity of IDS enzyme and confirmed by molecular analysis of IDS gene.Following diagnosis, different options of treatment were decided:...
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RESUMO Objetivo Monitorar o sistema auditivo central de crianças nascidas pequenas para a idade gestacional, por meio da avaliação eletrofisiológica da audição, para verificar a ocorrência de eventuais disfunções neurais nesse sistema.... more
RESUMO Objetivo Monitorar o sistema auditivo central de crianças nascidas pequenas para a idade gestacional, por meio da avaliação eletrofisiológica da audição, para verificar a ocorrência de eventuais disfunções neurais nesse sistema. Métodos Estudo longitudinal, cuja casuística foi composta por 23 crianças distribuídas em quatro grupos: 1) grupo de quatro crianças nascidas pequenas para a idade gestacional e a termo; 2) grupo de sete crianças nascidas pequenas para a idade gestacional e pré-termo; 3) grupo de quatro crianças nascidas com peso adequado para a idade gestacional e a termo; 4) grupo de oito crianças nascidas adequadas para a idade gestacional e pré-termo, cuja idade ao final da pesquisa foi de 3 anos (variação entre 34 e 39 meses). O critério de inclusão foi presença bilateral de emissões otoacústicas transientes. Todas as crianças foram submetidas ao potencial evocado auditivo de tronco encefálico ao nascimento, aos 6 meses e aos 3 anos de idade e à pesquisa do poten...
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RESUMO Objetivo Identificar por meio de uma revisão sistemática da literatura quais são as características da avaliação audiológica clínica de indivíduos com síndrome de Williams. Estratégia de pesquisa Inicialmente foi determinada a... more
RESUMO Objetivo Identificar por meio de uma revisão sistemática da literatura quais são as características da avaliação audiológica clínica de indivíduos com síndrome de Williams. Estratégia de pesquisa Inicialmente foi determinada a seguinte pergunta de pesquisa: “Quais são as características da avaliação auditiva clínica em indivíduos com síndrome de Williams?”. A partir desta, foi realizado um levantamento bibliográfico em 4 bases de dados, utilizando-se dos seguintes descritores: síndrome de Williams (Williams syndrome), perda auditiva (hearing loss) e audiologia (audiology). Critérios de seleção Foram selecionados artigos com nível de evidência 1 ou 2, publicados na íntegra nos idiomas português brasileiro ou inglês. Análise dos dados Foram analisados os resultados obtidos nos testes auditivos utilizados na rotina clínica, incluindo: imitanciometria, audiometria tonal, emissões otoacústicas e potencial evocado auditivo de tronco encefálico. Resultados 209 estudos foram encontra...
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The abnormal brain discharges observed in benign childhood epilepsy with centrotemporal spikes (BECTS) and temporal lobe epilepsy (TLE) are located close to areas responsible for auditory and language processing. This study aimed to... more
The abnormal brain discharges observed in benign childhood epilepsy with centrotemporal spikes (BECTS) and temporal lobe epilepsy (TLE) are located close to areas responsible for auditory and language processing. This study aimed to analyze the results of auditory event-related potentials (P300) in children with BECTS and TLE in order to assess whether the epileptic activity in centrotemporal and temporal regions may compromise the integrity and physiology of auditory system structures. This was a prospective, comparative, and cross-sectional study. Group I (GI) consisted of 13 children diagnosed with BECTS, group II (GII), 7 children diagnosed with TLE, and control group (GIII), 16 healthy children, with no hearing or academic complaints. After neurological and basic audiological assessments, P300 was applied. The P300 latency and amplitude were compared between groups. Regarding latency, GI showed 324.1 (+31.5) ms, GII 336.3 (+23.5) ms, and GIII 318 (+27.7) ms. Amplitudes were 4.8...
Research Interests: Psychology, Audiology, Epilepsy, Adolescent, Medicine, and 15 moreChildren, Temporal Lobe, Hearing, Prospective studies, Humans, Child, Female, Male, Temporal Lobe Epilepsy, Clinical Sciences, Auditory evoked Potentials, Action Potentials, Cross Sectional Studies, Acoustic Stimulation, and Child preschool
RESUMO O zumbido pode ser definido como a percepção consciente de um som, sem a presença de estimulação acústica externa. Considerando o prejuízo causado pelo zumbido e a falta de tratamentos definitivos, fica evidente a necessidade de... more
RESUMO O zumbido pode ser definido como a percepção consciente de um som, sem a presença de estimulação acústica externa. Considerando o prejuízo causado pelo zumbido e a falta de tratamentos definitivos, fica evidente a necessidade de alternativas para reabilitação de pessoas com zumbido. A hipótese é que o treinamento auditivo pode causar uma reorganização plástica desse sistema, promovendo uma melhora do sintoma. Objetivo: Verificar o efeito de um programa de treinamento auditivo em portadores de zumbido na percepção desse sintoma. Métodos: Participaram 12 indivíduos portadores de zumbido, divididos em dois grupos: Grupo Estudo (GE) e Grupo Controle (GC). Todos os indivíduos realizaram: audiometria; avaliação eletrofisiológica; acufenometria; aplicação do Tinnitus Handicap Inventory (THI) e avaliação do processamento auditivo (GIN - Gaps In Noise , Teste de Padrão de Frequência e Fala com Ruído). Após a avaliação, foram iniciados os treinamentos e o GE foi submetido ao treinament...
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Objetivo Acompanhar a maturação da via auditiva de lactentes nascidos pequenos para a idade gestacional (PIG), de acordo com a proporcionalidade corporal, nos primeiros seis meses de vida. Métodos Potencial Evocado Auditivo de Tronco... more
Objetivo Acompanhar a maturação da via auditiva de lactentes nascidos pequenos para a idade gestacional (PIG), de acordo com a proporcionalidade corporal, nos primeiros seis meses de vida. Métodos Potencial Evocado Auditivo de Tronco Encefálico (PEATE) realizado no período neonatal e aos seis meses de vida, em 59 lactentes, sendo 35 nascidos pequenos para a idade gestacional e assimétricos (PIG-A) e 24 simétricos (PIG-S), comparados a 59 lactentes nascidos com peso adequado (AIG), considerando a idade gestacional. Resultados Os lactentes PIG-A e PIG-S a termo e pré-termo evidenciaram processo maturacional auditivo (diminuição progressiva das latências do PEATE) significativo, do período neonatal aos seis meses de vida, o mesmo ocorrendo em relação aos AIG. Os grupos AIG a termo e pré-termo, bem como os grupos PIG-S e PIG-A não se diferenciaram do ponto de vista auditivo durante os seis meses, quando comparados entre si. Conclusão Os lactentes PIG com padrão simétrico e assimétrico e...
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Objectives: To assess the effects of noise and chemical exposure on peripheral and central auditory pathways in normal-hearing workers exposed to chemicals or high noise levels and compare the groups with each other and with workers not... more
Objectives: To assess the effects of noise and chemical exposure on peripheral and central auditory pathways in normal-hearing workers exposed to chemicals or high noise levels and compare the groups with each other and with workers not exposed to either of these agents. Methods: A total of 54 normal-hearing workers were divided into three groups (chemical, noise, control) and submitted to the following assessments: conventional and extended high-frequency pure-tone audiometry; transient and distortion-product otoacoustic emissions, the inhibitory effect of the efferent auditory pathway; and Staggered Spondaic Word (SSW) and Pitch Pattern Sequence (PPS) test. Results: There were no significant differences between the groups in extended high-frequency hearing thresholds. Significantly lower amplitudes were observed in the noise group for otoacoustic emissions. There were significantly more absences of the inhibitory effect of the efferent system in the noise group. There was no difference between the groups in the SSW test, while in PPS, the noise group performed worse than the control group. Conclusion: These findings suggest that noise exposure produced deleterious effects on the workers' peripheral and central auditory systems, despite their normal hearing thresholds. The chemical group did not have significantly different results from those of the control group. It is important that individuals exposed to noise or chemicals have their auditory pathways monitored with complementary assessments.