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Trichotilomania and Request for Hair Transplantation

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Trichotilomania and Request for Hair Transplantation Reza Bidaki 1, 2 , Sogol Alesaeidi 3 , Seyed-Ali Mostafavi 4 , Narges Ghanei Yakhdani 5 , * , Aida Farsham 6 , Mojtaba Babaei Zarch 7 1 Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2 Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 3 International University of Medical Science, Yazd, Iran 4 Psychiatry Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, IR Iran 5 Department of Dermatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 6 MS in Clinical psychology, Alzahra University, Tehran, Iran 7 Student Research Commitee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran * Corresponding author: Narges Ghanei Yakhdani, Department of Dermatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Tel: +98-3532632004; Fax: +98-3532623555; E-mail: Nargesgh73@yahoo.com. Abstract Introduction: Trichotillomania (TM) is a type of impulse control disorder with chronic hair pulling. It efects on behavior, feelings, thoughts and quality of life. Case Presentation: Te patient is a 28 year-old single woman that was referred to hair transplantation. She was worried about her appearance, cosmetic problems and marriage. Te physician noticed that she is a patient with trichotilomania type of impulse control disorder. Afer confrming the diagnosis of trichotillomonia by a psychiatrist, pharmacotherapy begun with Rispridone 1 mg at night, Fluvoxamine 50 mg/daily and Clomipramine 5 mg at night. Over nine months of treatment there were signifcant reductions in hair pulling. She was followed up and fnally, the response was acceptable. Conclusions: TM is a poorly understood disorder that requires more studies. Despite what we know about TM, those with the disorder report not receiving enough information for diagnose and treatment. However, the information presented in this paper can help us to prevent this disorder, reduceing the prevalence and selecting the appropriate treatment. © 2017. Focus on Sciences Submited: 03.14.2017 Accepted: 05.23.2017 Keywords: Trichotillomania Hair Transplantation Psychodermatology Focus on Sciences Aug 2017, Volume 3, Issue 3 Case Report DOI: 10.21859/focsci-03031413 INTRODUCTION Trichotillomania (TM) is an impulse control chronic behav- ioral disorder [1], characterized by the recurrent compulsive hair pulling from diferent parts of the body which can cause tension relief during the act [2] and it may be associated with major functional impairments and psychiatric comorbidities as well as infections or skin diseases in the hair pulling areas [3]. Some patients eat the hair afer pulling, which can cause masses, called trichobezoar [4, 5]. Its prevalence is below 1% [6]. Trichotillomania is diagnosed in all age and gender groups; with a notable onset peak at 12–13 [7]. Generally, it is a female dominant disorder. Te exact etiology is unknown, but it is likely that multiple genes confer to trichotillomania, because it may be more likely happens in twins and the mem- bers of the families with a past history of trichotillomania [8]. It may be difcult to treat and its treatment usually consists of both pharmacotherapy and psychotherapy [9]. CASE PRESENTATION Te patient is a 28 year-old single woman that was referred the hair transplantation clinic because of the long term, treat- ment resistant, scalp alopecia (Fig 1), But At the time the physician noticed that she is a patient with trichotilomania type of impulse control disorder, and referred her to psychol- ogist but although She denied her behavioral problem the dermatologist started Clomipramine 10 mg at bedtime and Fluoxetine 20 mg /daily and referred her to us. When she atended in our clinic she covered her head by a hat, without that, the patient’s appearance was notable for total al- opecia and the lack of both eyebrows. She was depressed with
Bidaki, et al. 2 motor tic in the form of eye blinking and worried about her appearance, cosmetic problems and decision for marriage. She reported a 4 year history of compulsive hair pulling, restricted to the scalp and eyebrows. She had the history of whole life anxiety disorder too. Te Symptoms frst begun 4 years ago when she had severe stresses about her future life, marriage and the fear of remaining alone, and afer that, symptoms fared times and times by increasing life stressors for example during educational period. When the frst symptoms begun, she was ashamed of that, so she referred to a dermatologist and denied that her hair loss was due to such behavior. She got diferent local and oral drugs but because of the treatment failure she was referred to hair transplantation clinic. During this time she had lower life stressors so afer a short time of local treatment she exhibited hairs of difering lengths; some were broken hairs with blunt ends, some new growth with tapered ends, and some broken mid-shaf [10]. She denied any other medical problems. She was from a low socioeconomic family and there was a history of obsessive compulsive disorder in her frst degree family. Afer establishing the diagnosis of trichotillomonia, pharmacotherapy begun with Rispridone 1 mg at night, Fluvoxamine 50 mg/daily and Clomipramine 5 mg at night. Over nine months of treat- ment there were signifcant reductions in hair pulling (Fig 2). Figure 1: Te Patient with Trichotilomania. Extensive Tonsure Pat- tern, Severe form Involving the Entire Scalp Sparing the Hair at the Marginal Zone and Eyebrows (Before Treatment) Figure 2: Te Patient with Trichotilomania. (Afer Psychopharma- cotherapy) DISCUSSION Good clinical practice begins with accurate assessment for reaching true diagnoses, then planning for treatment and f- nally assessing changes in severity of symptoms [11]. Assess- ment of TM needs gathering some information from difer- ent sources by a well-established interview performed by a psychiatrist. Our psychiatrist similarly tried to assess patient’s symptoms and its severity, functional impairments, comor- biditis and diferential diagnosis all based on DSM-5 criteria. Ten we tried to tailor a treatment for her and assessed the patient’s symptoms afer psychopharmacotherapy. A 28 year old woman was referred to our outpatient clinic of psychol- ogy in Yazd medical university, reporting a 4 year history of compulsive hair pulling, restricted to the scalp and eyebrows. She had the history of whole life anxiety disorder and depres- sion too. Instead of referring to psychiatrist, she was referred to dermatologist since She was ashamed of declaring her behavioral problem. As she denied her problem her dermatologist just used skip local and oral skin drugs to treat her and at last because of the treatment resistance referred her to the hair transplanta- tion clinic. Tis patient is diagnosed with trichotillomonia, because of the vast hair pulling area consist of the total re- gion of scalp and both eyebrows and, 4 years of atempts to deny her behavioral problem and going to the dermatologist to seek treatment instead of the psychologist. In this case afer Psychopharmacotherapy the patient was re-assessed. One objective and practical method of assessing the severity of trichotillomonia over the time is the use of photographs [11]. We snapped shot the patients’ primary pulling sites, be- fore psychopharmacotherapy and repeated again nine month afer the treatment, providing an objective way of assessing the treatment success. While such patients should usually atend psychological clinics in the frst step,but sometimes these patients will refuse a psychiatric referral because either they think, there is societal stigma associated with psychiat- ric illness or they do not believe in their psychiatric nature of disorder [12]. Terefore, it is essential for dermatologists to understand the common reasons of psychodermatological cases for example depression, anxiety, delusions, and obses- sive-compulsive disorder [12]. And refer these patients to psychiatrists or other mental health care professionals. Te most common approach includes combination of phar- macotherapy and psychotherapy. Choice of the drugs in adults are SSRIs [13]. Clomipramine, has shown moderate ef- fectiveness over placebo, N-acetylcysteine (NAC) has stron- gest empirical support in adults with TM [12]. Psycho- therapy in adults, adolescents and children consist of A wide variety of methods, including cognitive and behavioral ther- apies, supportive counseling, support groups, and hypnosis [14]. Tis paper is reported a patient with trichotillomonia, because of the vast hair pulling area consist of the total region of scalp and both eyebrows and, 4 years of her atempts to deny her behavioral problem and going to the dermatologist to seek treatment instead of the psychologist. CONCLUSIONS A case with trichotilomania may refer for hair transplantation so dermatologists should always be ready for referring them for psychotherapy. Whenever it is diagnosed, consultation with a psychiatrist about treatment of trichotilomania is necessary.
Focus on Sciences Case Report Aug 2017, Volume 3, Issue 3 Trichotilomania and Request for Hair Transplantation Reza Bidaki 1, 2, Sogol Alesaeidi 3, Seyed-Ali Mostafavi 4, Narges Ghanei Yakhdani 5 , *, Aida Farsham 6, Mojtaba Babaei Zarch 7 1 Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 2 Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 3 International University of Medical Science, Yazd, Iran 4 Psychiatry Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, IR Iran 5 Department of Dermatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 6 MS in Clinical psychology, Alzahra University, Tehran, Iran 7 Student Research Committee, Shahid Sadoughi University of Medical Sciences, Yazd, Iran DOI: 10.21859/focsci-03031413 Submitted: 03.14.2017 Accepted: 05.23.2017 Keywords: Trichotillomania Hair Transplantation Psychodermatology © 2017. Focus on Sciences * Corresponding author: Narges Ghanei Yakhdani, Department of Dermatology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Tel: +98-3532632004; Fax: +98-3532623555; E-mail: Nargesgh73@yahoo.com. Abstract Introduction: Trichotillomania (TTM) is a type of impulse control disorder with chronic hair pulling. It effects on behavior, feelings, thoughts and quality of life. Case Presentation: The patient is a 28 year-old single woman that was referred to hair transplantation. She was worried about her appearance, cosmetic problems and marriage. The physician noticed that she is a patient with trichotilomania type of impulse control disorder. After confirming the diagnosis of trichotillomonia by a psychiatrist, pharmacotherapy begun with Rispridone 1 mg at night, Fluvoxamine 50 mg/daily and Clomipramine 5 mg at night. Over nine months of treatment there were significant reductions in hair pulling. She was followed up and finally, the response was acceptable. Conclusions: TTM is a poorly understood disorder that requires more studies. Despite what we know about TTM, those with the disorder report not receiving enough information for diagnose and treatment. However, the information presented in this paper can help us to prevent this disorder, reduceing the prevalence and selecting the appropriate treatment. INTRODUCTION Trichotillomania (TTM) is an impulse control chronic behavioral disorder [1], characterized by the recurrent compulsive hair pulling from different parts of the body which can cause tension relief during the act [2] and it may be associated with major functional impairments and psychiatric comorbidities as well as infections or skin diseases in the hair pulling areas [3]. Some patients eat the hair after pulling, which can cause masses, called trichobezoar [4, 5]. Its prevalence is below 1% [6]. Trichotillomania is diagnosed in all age and gender groups; with a notable onset peak at 12–13 [7]. Generally, it is a female dominant disorder. The exact etiology is unknown, but it is likely that multiple genes confer to trichotillomania, because it may be more likely happens in twins and the members of the families with a past history of trichotillomania [8]. It may be difficult to treat and its treatment usually consists of both pharmacotherapy and psychotherapy [9]. CASE PRESENTATION The patient is a 28 year-old single woman that was referred the hair transplantation clinic because of the long term, treatment resistant, scalp alopecia (Fig 1), But At the time the physician noticed that she is a patient with trichotilomania type of impulse control disorder, and referred her to psychologist but although She denied her behavioral problem the dermatologist started Clomipramine 10 mg at bedtime and Fluoxetine 20 mg /daily and referred her to us. When she attended in our clinic she covered her head by a hat, without that, the patient’s appearance was notable for total alopecia and the lack of both eyebrows. She was depressed with Bidaki, et al. motor tic in the form of eye blinking and worried about her appearance, cosmetic problems and decision for marriage. She reported a 4 year history of compulsive hair pulling, restricted to the scalp and eyebrows. She had the history of whole life anxiety disorder too. The Symptoms first begun 4 years ago when she had severe stresses about her future life, marriage and the fear of remaining alone, and after that, symptoms flared times and times by increasing life stressors for example during educational period. When the first symptoms begun, she was ashamed of that, so she referred to a dermatologist and denied that her hair loss was due to such behavior. She got different local and oral drugs but because of the treatment failure she was referred to hair transplantation clinic. During this time she had lower life stressors so after a short time of local treatment she exhibited hairs of differing lengths; some were broken hairs with blunt ends, some new growth with tapered ends, and some broken mid-shaft [10]. She denied any other medical problems. She was from a low socioeconomic family and there was a history of obsessive compulsive disorder in her first degree family. After establishing the diagnosis of trichotillomonia, pharmacotherapy begun with Rispridone 1 mg at night, Fluvoxamine 50 mg/daily and Clomipramine 5 mg at night. Over nine months of treatment there were significant reductions in hair pulling (Fig 2). Figure 1: The Patient with Trichotilomania. Extensive Tonsure Pattern, Severe form Involving the Entire Scalp Sparing the Hair at the Marginal Zone and Eyebrows (Before Treatment) DISCUSSION Good clinical practice begins with accurate assessment for reaching true diagnoses, then planning for treatment and finally assessing changes in severity of symptoms [11]. Assessment of TTM needs gathering some information from different sources by a well-established interview performed by a psychiatrist. Our psychiatrist similarly tried to assess patient’s symptoms and its severity, functional impairments, comorbiditis and differential diagnosis all based on DSM-5 criteria. Then we tried to tailor a treatment for her and assessed the patient’s symptoms after psychopharmacotherapy. A 28 year old woman was referred to our outpatient clinic of psychology in Yazd medical university, reporting a 4 year history of compulsive hair pulling, restricted to the scalp and eyebrows. She had the history of whole life anxiety disorder and depression too. Instead of referring to psychiatrist, she was referred to dermatologist since She was ashamed of declaring her behavioral problem. As she denied her problem her dermatologist just used skip local and oral skin drugs to treat her and at last because of the treatment resistance referred her to the hair transplantation clinic. This patient is diagnosed with trichotillomonia, because of the vast hair pulling area consist of the total region of scalp and both eyebrows and, 4 years of attempts to deny her behavioral problem and going to the dermatologist to seek treatment instead of the psychologist. In this case after Psychopharmacotherapy the patient was re-assessed. One objective and practical method of assessing the severity of trichotillomonia over the time is the use of photographs [11]. We snapped shot the patients’ primary pulling sites, before psychopharmacotherapy and repeated again nine month after the treatment, providing an objective way of assessing the treatment success. While such patients should usually attend psychological clinics in the first step,but sometimes these patients will refuse a psychiatric referral because either they think, there is societal stigma associated with psychiatric illness or they do not believe in their psychiatric nature of disorder [12]. Therefore, it is essential for dermatologists to understand the common reasons of psychodermatological cases for example depression, anxiety, delusions, and obsessive-compulsive disorder [12]. And refer these patients to psychiatrists or other mental health care professionals. The most common approach includes combination of pharmacotherapy and psychotherapy. Choice of the drugs in adults are SSRIs [13]. Clomipramine, has shown moderate effectiveness over placebo, N-acetylcysteine (NAC) has strongest empirical support in adults with TTM [12]. Psychotherapy in adults, adolescents and children consist of A wide variety of methods, including cognitive and behavioral therapies, supportive counseling, support groups, and hypnosis [14]. This paper is reported a patient with trichotillomonia, because of the vast hair pulling area consist of the total region of scalp and both eyebrows and, 4 years of her attempts to deny her behavioral problem and going to the dermatologist to seek treatment instead of the psychologist. CONCLUSIONS Figure 2: The Patient with Trichotilomania. (After Psychopharmacotherapy) 2 A case with trichotilomania may refer for hair transplantation so dermatologists should always be ready for referring them for psychotherapy. Whenever it is diagnosed, consultation with a psychiatrist about treatment of trichotilomania is necessary. Bidaki, et al. ACKNOwLEDGMENTS There is no acknowledgment for the present study. 5. 6. CONFLICTS OF INTEREST There is no conflicts of interest to declare. 7. FUNDING Not applicable. AUTHORS’ CONTRIBUTION This work was carried out in collaboration between all authors. REFERENCES 1. 2. 3. 4. Association AP. Diagnostic and statistical manual of mental disorders. Arlington, USA: American Psychiatric Association; 2013. Fathi Nejad A, Ranjbar E, Fathi Nejad H, Sadr Mohammadi R, Rajabi Z, Mostafavi S-A, et al. Trichotillomania (Hair-Pulling) in a 4.5-YearOld Girl. Thrita. 2016;5(1). DOI: 10.5812/thrita.31376 du Toit PL, van Kradenburg J, Niehaus DJ, Stein DJ. Characteristics and phenomenology of hair-pulling: an exploration of subtypes. Compr Psychiatry. 2001;42(3):247-56. DOI: 10.1053/comp.2001.23134 PMID: 11349246 Bouwer C, Stein DJ. Trichobezoars in trichotillomania: case report and literature overview. Psychosom Med. 1998;60(5):658-60. PMID: 9773774 8. 9. 10. 11. 12. 13. 14. Swedo SE, Leonard HL. Trichotillomania. An obsessive compulsive spectrum disorder? Psychiatr Clin North Am. 1992;15(4):777-90. 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DOI: 10.2340/00015555-1674 PMID: 24096547 Franklin ME, Zagrabbe K, Benavides KL. Trichotillomania and its treatment: a review and recommendations. Expert Rev Neurother. 2011;11(8):1165-74. DOI: 10.1586/ern.11.93 PMID: 21797657 Wong JW, Koo JY. Psychopharmacological therapies in dermatology. Dermatol Online J. 2013;19(5):18169. PMID: 24011270 Woods DW, Houghton DC. Diagnosis, evaluation, and management of trichotillomania. Psychiatr Clin North Am. 2014;37(3):301-17. DOI: 10.1016/j.psc.2014.05.005 PMID: 25150564 Woods DW, Flessner C, Franklin ME, Wetterneck CT, Walther MR, Anderson ER, et al. Understanding and treating trichotillomania: what we know and what we don’t know. Psychiatr Clin North Am. 2006;29(2):487-501, ix. DOI: 10.1016/j.psc.2006.02.009 PMID: 16650719 3
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