Dissociation Constant
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Recent papers in Dissociation Constant
HIV-1 integrase is responsible for one of the key steps of the viral replication, integration of the viral cDNA into the host cell genome. Integration inhibition leads to complete block of the virus replication. In this study inhibition... more
The pharmacological profiles of D1- and D2-like dopamine receptors were investigated for native brain receptors in the leopard frog, Rana pipiens, using direct binding assays, which characterize functional receptors rather than assess... more
A keratinase enzyme was isolated and purified from a feather-degrading culture of Aspergillus oryzae. Fractional precipitation of the crude enzyme with ethanol, acetone and ammonium sulfate yielded 21 fractions. The fraction obtained at... more
We have determined or redetermined the calcium dissociation constants of seven BAPTA-type buffers with KD's in the range from 0.4 microM to about 20 mM in 300 mM KCl. These include four newly synthesized ones: 5-nitro... more
The acid dissociation constant is an important physicochemical parameter of a substance, and knowledge of it is of fundamental importance in a wide range of applications and research areas. We present a critical review of published... more
Enzymes utilize substrate binding energy both to promote ground state association and to selectively lower the energy of the reaction transition state.i The monomeric homing endonuclease I-AniI cleaves with high sequence specificity in... more
The pK 1* and pK 2* of H2SO3 have been determined in NaCl solutions as a function of ionic strength (0.1 to 6 m) and temperature (5 and 25 °C). The extrapolated values in water were found to be in good agreement with literature data. The... more
The effect of single and binary solvents on electronic absorption spectra of 1,3-bis[(3-(2-pyridyl) pyrazol-1 ylmethyl)] benzene (1,3-PPB) was examined. 1,3-PPB has two absorption maxima (250 and 280 nm) due to pyridyl pyrazole and... more
The solubilities of lanthanum carbonate La2(CO3)3·8H2O in solutionsS 0([H+]=H mol kg−1, [Na+]=(I−H) mol kg−1, [ClO 4 − ]=I mol kg−1) at various fixed partial pressures of CO2 have been investigated at 25.0 °C. The hydrogen ion molality... more
Vitreous coatings can be used as a means for the corrosion protection of metals and alloys due to their excellent dielectric properties. Their use is of particular interest in the case of highly aggressive media (different pH levels,... more
We analyzed the role of Ab affinity on Ab-mediated Ag uptake and presentation to T cells. Hen egg white lysozyme (HEL) was captured by bifunctional hybrid proteins (Fv-MalE) in which the variable fragment (Fv) of the anti-HEL mAb D1.3 was... more