LIQUID

Abstract: Herein, a sensitive and rapid reversed phase HPLC assay was devel-oped for the simultaneous determination of 1,4-benzodiazepines and tricyclic antidepressants in human saliva and pharmaceutical formulations using colchi-cine as internal standard. Diode array ...

... Dosage Forms Using an Automated HPLC System Hassan Y. Aboul-Enein,1'* Rajaa F. Hussein,2 Manasen A. Radwan,3 Ahmad Yusuf,2 Wijdan ... Very few methods for the assay of ТАМ have been published.t4-7] However, mese methods are not suitable for the assay of ТАМ in ...

Abstract The effects of the chaotropic agent perchloric acid on high temperature liquid chromatography (HTLC) with water as mobile phase have been investigated over a temperature range from 130° C to 200° C. Aniline, N-methylaniline, 3-ethylaniline and N, ...

Certain plants of the daily human diet are an important source of beneficially healthy flavonoids, possessing significant pharmacological activities against various diseases. Flavonoids display an array of chemical diversity based on relative positioning of benzopyrano moiety and aromatic ring. Due to structural diversity of these molecules, simultaneous quantification of these molecules in plant materials becomes difficult. In the present study, a rapid, simple, and sensitive, High Performance Liquid Chromatography-Photo Diode Array Mass Spectrometry (HPLC-PDA-MS-MS) method was developed for the simultaneous determination of three different classes of flavonoids,namely, isoflavonoids, flavanones, and flavonols in legume seeds, vegetables, fruits, and medicinal plants. The method was evaluated for validation parameters, such as linearity, accuracy, precision, limit of detection (LOD), limit of quantification (LOQ), specificity, selectivity, and compound stability. The developed method was applied on extracts of different plant samples for quantification of the flavonoids daidzein, genistein, naringenin, quercetin, kaempferol, and rutin. Method developed in this study can be used in the quality control and standardization of plant extracts as well as herbal drugs and formulations. Supplemental materials are available for this article. Go to the publisher's online edition of the Journal of Liquid Chromatography & Related Technologies to view the free supplemental file.

A simple, stability indicating, reversed phase high performance liquid chromatographic method has been developed for the determination of nicardipine hydrochloride (NC) in the presence of its degradation products. Reversed phase chromatography was conducted using a Hibar‐C18 (150×4.6 mm i.d.) stainless steel column at ambient temperature with UV‐detection at 238 nm. Microemulsion mobile phase consisting of 0.175 M sodium dodecyl sulphate, 10% n‐propanol, 0.3%

In this article we describe the self-assembling properties of alkyl substituted xylitols in relation to both thermotropic and lyotropic liquid crystalline mesophases. Three series of substituted xylitols were prepared where aliphatic chains of varying length were attached ...

... CHROM. & EL . TECHNOL., 19(3), 383-392 (1996) HPLC SEPARATION OF NADOLOL AND ENANTIOMERS ON CHIRALCEL OD COLUMN Hassan Y. Aboul-Enein,* Laila I. Abou-Basha ... REFERENCES 1. BR Patel,, JJ Kirschbaum, RBJ Poet, J. Phann. Sci. 70, 336 (1981). ...

... The proposed method appears to be an adequate method for quality control in the coffeeindustry. INTRODUCTION ... Coffee Samples Two samples from Brazil and Ivory Coast, before and after roasting were provided by a local coffee industry. ...