Mitomycin C
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Recent papers in Mitomycin C
Serratia plymithicum J7 culture supernatant displayed activity against many pathogenic strains of Erwinia amylovora, the causal agent of the most serious bacterial disease of apple and pear trees, fire blight, and against Klebsiella... more
The aim of this study was to set up a method for quantification of plasma mitomycin C (MMC) concentrations during intravesical chemotherapy delivered in the presence of local bladder hyperthermia (HT). In comparison with existing methods,... more
The EGF receptor (EGFR) upon activation signals increased cell movement. However, the domains within the receptor, and the pathway which trigger movement are undefined. We expressed EGFR mutants at physiologic levels in receptor-devoid... more
Nucleotide excision repair (NER) in Escherichia coli repairs DNA by incising the damaged strand on the... more
Pseudomonas aeruginosa strain BS2 has been demonstrated to have an ability to produce potent biosurfactant, an ecofriendly substitute to synthetic surfactants from distillery and whey wastes and capable of reducing the pollution load of... more
The habitats for the two major Leptospira spp. differ. The main habitat of L. biflexa is soil and water, whereas L. interrogans primarily resides in the renal tubules of animals. We investigated whether these two species, along with L.... more
Systemic anticancer chemotherapy is immunosuppressive and mostly induces nonimmunogenic tumor cell death. Here, we show that even in the absence of any adjuvant, tumor cells dying in response to anthracyclins can elicit an effective... more
espanolObjetivo: Estudiar el efecto de la mitomicina C (MMC) en el engrosamiento corneal tras queratectomia subepitelial con laser excimer (LASEK). Metodos: Realizamos un estudio prospectivo, controlado, enmascarado de 64 ojos... more
NAD(P)H:quinone oxidoreductase (DT-diaphorase; DTD) is an obli gate two-electron reducÃase which may play a role in the bioactivation of antitumor quiñones such as mitomycin C (MMC). We studied 10 colon carcinoma cell lines showing... more
Aims: To study the effect of silicone tube intubation with and without mitomycin c in revision of external dacryocystorhinostomy following failed dacryocystorhinostomy (DCR) surgery. Settings and Design: A Retrospective study. Materials... more
Purpose: To report the effectiveness of combined surgery for neovascular glaucoma. Methods: Six eyes of six consecutive patients with neovascular glaucoma underwent the combined surgery: trabeculectomy with Mitomycin C, Pars Plana... more
Objectives: To determine the efficacy, best indications, and regimens of intravesical adjuvant instillations in case of non-muscle-invasive bladder tumours. Methods: The authors analyse the most significant articles of the litera- ture to... more
Aim. To verify the rationale of a pelvic stop-flow technique for the perfusion of high-doses of mitomycin C and anthacyclines in patients with inoperable, recurrent pelvic cancer.Methods. The stop-flow technique was realized by using... more
The present study investigated the effect of mitomycin C (MMC) on cell viability, apoptosis, and transforming growth factor beta-induced protein (TGFBIp) expression in cultured normal corneal fibroblasts and heterozygote or homozygote... more
Objectives: To compare different mef (A) elements of Streptococcus pyogenes for a possible chimeric genetic nature, ie a transposon inserted into a prophage. Methods: Eleven S. pyogenes isolates with efflux-mediated erythromycin... more
To prevent the development of secondary cataract, mitomycin C (MC, 0.2 mg/ml) and 5-fluorouracil (5-FU, 50 mg/ml) were introduced in the irrigating solution (BSS Plus) during an extracapsular lens extraction in albino rabbits. Cellular... more