vitamin B12
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Recent papers in vitamin B12
Background: The Neurodegenerative diseases are increasingly affecting the elderly with a severe impact on their brain health. There is a wide gap in supplementation based studies for increasing the cognition levels of the geriatric... more
Folic acid and cobalamin are B-group vitamins that play an essential role in many cellular processes. Deficiency in one or both of these vitamins causes megaloblastic anaemia, a disease characterized by the presence of megaloblasts.... more
Vitamin B12 (cobalamin) deficiency occurs primarily as a result
of insufficient dietary intake or poor absorp-tion. There is widespread global prevalence of vitamin B12 deficiency, resulting in considerable morbidity.
of insufficient dietary intake or poor absorp-tion. There is widespread global prevalence of vitamin B12 deficiency, resulting in considerable morbidity.
Studies have shown that nutritional intake and metabolism may play an important role in the causes and treatment of several female reproductive health issues. The water soluble vitamins B6, B12 and C have been suggested to play important... more
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People with Vitamin B12 deficiency are susceptible to the symptoms of the virus because of its destructive effect on their cell membranes and immune system.
The June 2020 issue of the newsletter examines this in more detail
The June 2020 issue of the newsletter examines this in more detail
A nutritional deficiency in younger age group includes both micro and macronutrient deficiencies leading to protein calorie malnutrition, failure to thrive, compromised immune function and nutritional anemia. Deficiencies of iron, vitamin... more
Dementia is a worldwide health problem which affects millions of patients; Alzheimer's disease (AD) and subcortical vascular dementia (sVAD) are the two most frequent forms of its presentation. As no definite therapeutic options have been... more
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Background: Reticulocytes are the youngest erythrocytes released from the bone marrow into the blood and they circulate for 1-2 days before becoming mature erythrocytes. In literature, there were studies about reticulocyte parameters that... more
Vitamin B12 defiiency causes haematological, gastrointestinal, psychiatric and neurological diseases. Subacute combined degeneration (SCD) of the spinal cord, characterised by degeneration of the lateral and posterior columns, is often... more
In this study, we developed a selective and sensitive inner filter effect-based method by thioglycolic acid capping CdTe quantum dots (TGA-CdTe QDs) for the quantitative determination of Vitamin B12 (B12). The effect of all experimental... more
Cobalamins are ubiquitous cobalt-based corrinoid cofactors of various transferases, exemplified by methyltransferases and adenosyltransferases. The cobalt oxidation state in these cobalamins directly influences their coordination... more
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The occurrence of megaloblasts in the bone marrow characterizes megaloblastic anemia. Megaloblastic anemia is the result of folate and vitamin B12 deficiency in many cases. It is either caused due to nutritional deficiency of folates or... more
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The use of adsorption methods to recover vitamin B12 (VB12) from wastewater has been increasingly studied. However, there is a lack of knowledge on optimization of the methods. This study established a feedback network to evaluate... more
The radical pair that results from photolysis of adenosylcob(III)alamin (AdoCblIII) undergoes primary geminate recombination with a first-order rate constant of 1 x l09 s-l. In contrast, methylcob(III)alamin (CH3CbIII) and... more
Cobalamins are stored in high concentrations in the human liver and thus are available to participate in the regulation of hepatotropic virus functions. We show that cyanocobalamin (vitamin B12) inhibited the HCV internal ribosome entry... more
Background: The relation between key enzymes in regulation of folate metabolism and male infertility is the subject of numerous studies. We aimed to determine whether 5, 10-methylenetetrahydrofolate reductase (MTHFR) C677T and methionine... more
Research shows that serum Vitamin B12 levels are reduced in diabetes including gestational diabetes. We sought to compare serum cobalamin between pregnant females diagnosed with gestational diabetes mellitus (GDM) and healthy controls and... more
BACKGROUND: An important biological factor suggested in the pathophysiology of (recurrent) Major Depressive Disorder (MDD) concerns a polymorphism in a gene encoding for the MTHFR-enzyme of the one-carbon (1-C)-metabolism. Integratively... more
The ability of enzymes to harness free-radical chemistry allows for some of the most amazing transformations in nature, including reduction of ribonucleotides and carbon skeletal rearrangements. Enzyme cofactors involved in this chemistry... more
Adından da anlaşılacağı üzere çeşitli biyolojik süreçlerde yer alan B vitaminin önemli bir parçasıdır. Fiziksel ve zihinsel sağlık için en önemli vitaminlerden biridir. Kırmızı kan hücresi oluşumu , nörolojik işlevler ve DNA sentezi gibi... more
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