5 days ago · We present QUANTA, a computational strategy to distinguish transcriptionally silent genes and analyze their regulation. ... Several cytoplasmic polyadenylation ...
Jun 14, 2024 · miRNAs are known to regulate posttranscriptional gene expression through recognition of base pairs, particularly in the 3′-UTRs of mRNAs in the cytoplasm. This ...
Jun 17, 2024 · Our above-described genome-wide analysis prompted the hypothesis that UTR variants that disrupt critical RNA regulatory elements may be linked to pathogenicity.
Jun 24, 2024 · Computational analysis of Cyclin D1 gene SNPs and association with breast cancer. Circular RNA Circ_0000677 promotes cell proliferation by regulating microRNA- ...
Jun 14, 2024 · Gene expression is regulated at several levels, transcriptionally, translationally, and even at the splicing stage. Alternative splicing of some genes gives ...
Jun 24, 2024 · The Rajewsky lab studies how RNA regulates gene expression in health and disease. We are collaborating with various clinicians and have built up human brain ...
Jun 28, 2024 · Polyadenine (Poly(A)) binding proteins (PABPs) make up a class of regulatory proteins that play critical roles in protecting the poly(A) tails of cellular mRNAs ...
Jun 20, 2024 · It is believed that as much as 30% of human genes are regulated by miRNAs [3]. ... The cyclins (CDK/CCN) family, the CPBE (cytoplasmic polyadenylation ...
Jun 24, 2024 · Here, we optimized and conducted massively par- allel exon deletion and splice-site mutation screens in human cell lines to identify exons that regulate ...
Jun 29, 2024 · Gene expression in mammals is regulated by many cis-regulatory elements ... "Computational inference of gene regulatory networks: Approaches, limitations ...