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    Levofloxacin

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    Muhammad Arsalan
    Levofloxacin is an antibiotic of the fluoroquinolone class used to treat various bacterial infections such as sinusitis, bronchitis, pneumonia, prostatitis, and UTIs. It works by inhibiting bacterial DNA replication. Common adverse effects include dizziness, nausea, tendon damage, and risk of seizures. It interacts with various other drugs and use requires caution in elderly, children, and pregnant/breastfeeding women due to safety concerns.

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    Levofloxacin

    Uploaded by

    Muhammad Arsalan
    644 views2 pages
    Levofloxacin is an antibiotic of the fluoroquinolone class used to treat various bacterial infections such as sinusitis, bronchitis, pneumonia, prostatitis, and UTIs. It works by inhibiting bacterial DNA replication. Common adverse effects include dizziness, nausea, tendon damage, and risk of seizures. It interacts with various other drugs and use requires caution in elderly, children, and pregnant/breastfeeding women due to safety concerns.

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    levofloxacin

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    Levofloxacin is an antibiotic of the fluoroquinolone class used to treat various bacterial infections such as sinusitis, bronchitis, pneumonia, prostatitis, and UTIs. It works by inhibiting bacterial DNA replication. Common adverse effects include dizziness, nausea, tendon damage, and risk of seizures. It interacts with various other drugs and use requires caution in elderly, children, and pregnant/breastfeeding women due to safety concerns.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    644 views2 pages

    Levofloxacin

    Uploaded by

    Muhammad Arsalan
    Levofloxacin is an antibiotic of the fluoroquinolone class used to treat various bacterial infections such as sinusitis, bronchitis, pneumonia, prostatitis, and UTIs. It works by inhibiting bacterial DNA replication. Common adverse effects include dizziness, nausea, tendon damage, and risk of seizures. It interacts with various other drugs and use requires caution in elderly, children, and pregnant/breastfeeding women due to safety concerns.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
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    LEVOFLOXACIN

    Therapeutic Category Antibiotic Pharmacologic class: Fluoroquinolone Use\ Indications Acute bacterial sinusitis Mild to moderate skin and skin structure infections Acute bacterial worsening of chronic bronchitis Community-acquired pneumonia To prevent inhalation anthrax after confirmed or suspected exposure to Bacillus anthracis Chronic bacterial prostatitis Complicated skin and skin-structure infections caused by methicillin-sensitive S. aureus, Nosocomial pneumonia caused by methicillin-susceptible S. aureus, Complicated UTI Acute pyelonephritis caused by E. coli Travelers diarrhea Pharmacological Effects Inhibits bacterial DNA gyrase and prevents DNA replication, transcription, repair, and recombination in susceptible bacteria. Adverse Reaction CNS: encephalopathy, seizures, dizziness, headache, insomnia. GI: pseudomembranous colitis, constipation, diarrhea, dyspepsia, nausea, vomiting. GU: vaginitis. Hematologic: lymphopenia, eosinophilia, hemolytic anemia. Metabolic: hypoglycemia. Musculoskeletal: back pain, tendon rupture. Respiratory: allergic pneumonitis, dyspnea. Skin: erythema multiforme, Stevens- Johnson syndrome, photosensitivity,pruritus, rash. Precautions/Warnings/Contraindication Drug is associated with increased risk of tendinitis and tendon rupture, especially in patients older than age 60 and those with heart, kidney, or lung transplants. Contraindicated in patients hypersensitive to drug, its components, or other fluoroquinolones. Use cautiously in patients with history of seizure disorders or other CNS diseases, such as cerebral arteriosclerosis. Use cautiously in children younger than 18 years Pregnancy category: C Breast-feeding: Use cautiously

    Interactions: Antiarrhythmics, chlorpromazine, erythromycin, fluconazole, imipramine, ziprasidone: May increase risk of life-threatening cardiac arrhythmias. Avoid use together. Antidiabetics: May alter glucose level. Iron salts: May decrease absorption of levofloxacin, reducing anti-infective response. Separate doses by at least 2 hours. NSAIDs: May increase CNS stimulation. Monitor patient for seizure activity. Steroids: May increaserisk of tendinitis and tendon rupture. Monitor patient for tendon pain or inflammation Dosing Adult: 500-750 mg P.O. or I.V. infusion over 90 minutes/day Brand Available: Capsules: Leflox 500mg Qumic 500mg Parentrals Leflox 500mg/100ml Qumic 500mg/100ml

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