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    Isoniazid

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    Michael Kuzbyt
    Isoniazid is an antitubercular drug taken orally once daily at 8:30 AM to treat and prevent tuberculosis. It works by interfering with the lipid and nucleic acid metabolism of growing bacteria. Common side effects include peripheral neuropathy, nausea, heartburn, dizziness, and hepatitis. The medication can cause liver toxicity, especially when combined with alcohol or other hepatotoxic drugs like rifampin. Nursing care involves monitoring for side effects like weakness, jaundice, and visual changes as well as assessing liver function tests.

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    Isoniazid

    Uploaded by

    Michael Kuzbyt
    623 views2 pages
    Isoniazid is an antitubercular drug taken orally once daily at 8:30 AM to treat and prevent tuberculosis. It works by interfering with the lipid and nucleic acid metabolism of growing bacteria. Common side effects include peripheral neuropathy, nausea, heartburn, dizziness, and hepatitis. The medication can cause liver toxicity, especially when combined with alcohol or other hepatotoxic drugs like rifampin. Nursing care involves monitoring for side effects like weakness, jaundice, and visual changes as well as assessing liver function tests.

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    drug card isoniazid

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    Isoniazid is an antitubercular drug taken orally once daily at 8:30 AM to treat and prevent tuberculosis. It works by interfering with the lipid and nucleic acid metabolism of growing bacteria. Common side effects include peripheral neuropathy, nausea, heartburn, dizziness, and hepatitis. The medication can cause liver toxicity, especially when combined with alcohol or other hepatotoxic drugs like rifampin. Nursing care involves monitoring for side effects like weakness, jaundice, and visual changes as well as assessing liver function tests.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    623 views2 pages

    Isoniazid

    Uploaded by

    Michael Kuzbyt
    Isoniazid is an antitubercular drug taken orally once daily at 8:30 AM to treat and prevent tuberculosis. It works by interfering with the lipid and nucleic acid metabolism of growing bacteria. Common side effects include peripheral neuropathy, nausea, heartburn, dizziness, and hepatitis. The medication can cause liver toxicity, especially when combined with alcohol or other hepatotoxic drugs like rifampin. Nursing care involves monitoring for side effects like weakness, jaundice, and visual changes as well as assessing liver function tests.

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    Clinical Medications Worksheets Generic Name

    ISONIAZI D

    Peak
    1-2Hr

    Trade Name INH, Isotamine, Nydrazid Onset

    Classification
    Antitubercular drug

    Dose
    300mg

    Route
    PO

    Time/frequency
    Daily 0830

    Duration
    2-5Hr

    For IV meds, compatibility with IV drips and /or solutions Nursing Implications (what to focus on) Contraindications/warnings/interactions
    Severe hypersensitivity to isoniazid or in clients with previous associated hepatic injury or side effects. Acute liver disease. Sometimes severe and fatal hepatitis can occur even after several months of therapy (daily alcohol users are at increased risk) Use caution for treatment of renal tuberculosis in clients with impaired renal function (EToH abuse) use lowest dose possible.

    Mechanism of action and indications (Why med ordered)


    Prophylaxis of Tuberculosis caused by human, Bovine and BCG Strains of Mycobacterium tuberculosis. Action: The most effective tuberculostatic agent. Interferes with lipid and nucleic acid metabolism of growing bacteria, resulting in the alteration of the bacterial wall.

    Common side effects


    Peripheral neuropathy, N&V, Heartburn, dizziness, optic neuritis, hepatitis.

    Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine medicines (ask patient specifically) Benzodiazepines Diazepam (PRN) Cause and increased effect of the diazepam. Rifampin Additive liver toxicity

    Be sure to teach the patient the following about this medication


    Take on empty stomach Consume 2-3L of fluids per day Avoid alcohol to prevent hepatic toxicity Pyridoxine(B6) is given to prevent peripheral neuritis Withhold drug if weakness or jaundice is occurring Report visual disturbances Monitor closely (Diabetes) F/U assessments and eye exams

    Nursing Process- Assessment (Pre-administration assessment)


    -Measure AST and ALT, obtain baseline vitals and labs. -Reduce dose with dysfunction and or alcoholism - CxR and AFB Sputums

    Assessment Why would you hold or not give this med?


    LFT (damage to liver), Allergies,

    Evaluation
    Negative sputum cultures for AFB Decrease neurotoxic drug effects Symptomatic improvement (decrease fever, secretions, increase appetite.)

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