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Cell Cycle

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Advanced Biology

The Cell Cycle


The Cell Cycle

10.1
Interphase
 G1 – Growth phase
 Cell
carries out its normal metabolic
processes
S – Synthesis
 Cell replicates its DNA (chromosomes)
 G2 – Growth phase
 Cell
carries out its normal metabolic
processes

10.1
Mitotic Phase
 Consists of
 Mitosis– cell divides
 Cytokinesis – two new cells split apart

10.1
Growth, Reproduction and Repair
 Unicellular organisms
 Reproduce by cell division
 Multicellular organisms
 Develop from fertilized cells
 Grow and repair of damaged cells through
division

10.2
Prokaryotes vs. Eukaryotes
 Prokaryotic DNA is not bound in a nucleus
 Prokaryotic cells contain circular DNA called plasmids

10.2
Chromosome
Replication

10.3
Mitosis

10.4/5
Mitosis

10.4/5
Mitosis

10.4/5
Mitosis – Plant Cells

10.4/5
Spindle Apparatus
 The mitotic spindle
 Isan apparatus of
microtubules that
controls chromosome
movement during
mitosis

10.6
Cytokinesis: Animal Cells
 In animal cells
 Cytokinesis occurs
by a process known
as cleavage, forming
a cleavage furrow
Cleavage furrow 100 µm

Contractile ring of
Daughter cells
microfilaments

Cleavage of an animal cell (SEM)


10.7
Cytokinesis: Plant Cells

 In plant cells
 A cell plate forms
during cytokinesis

Vesicles Wall of 1 µm
forming patent cell Cell plate New cell wall
cell plate

Daughter cells
10.7 Cell plate formation in a plant cell (SEM)
Binary Fission

10.8
Cell Cycle Control

10.9
Growth Factors
 Stimulate cells to
divide
 Without growth
factors cells “freeze”
in G1
 PDGF – platelet-
derived growth
factor

10.9
Two Types of Growth Inhibition
 Density-dependent
inhibition
 Crowded cells stop
dividing
 Anchorage dependent
inhibition
 Cells must be attached to
a sub layer to divide
 Cancer cells
 Exhibit no inhibition

10.10
Cancer Cells
10.10

 Do not respond normally to the body’s control


mechanisms
 Form tumors
 Tumors can metastasize
 Move to new areas of the body through blood or lymph and
form new tumors

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