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science: biology 20
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1.1 Cell Biology


STRUCTURE OF A CELL
INTRODUCTION TO CELLS
Cell
Robert Hooke  smallest unit of life responsible for all
 created the primitive microscope life’s processes
 all his findings from the instrument  has three main components: the cell
were published with the title membrane, cytoplasm, and DNA
“Micrographia” in 1665  lowest level of organization in any
 coined the scientific term “cell” from life form
the little holes he observed in corks
(dead cells with remaining Unicellular
membrane) that resembled the cells  organism made up of a singular cell
or tiny rooms the monks lived in
Multicellular
Antonie von Leeuwenhoek  made up of multiple cells
 Dutch lens crafter inspired by
Hooke’s observations Mycoplasmas
 was able to observe living and  smallest cells known
unicellular organisms (sperm) in the
1670s
TYPES OF CELLS
 also observed protists (unicellular,
eukaryotic, possessing cell walls)
and called them “animacules” Eukaryotic Cells
 contains the organelles (nucleus and
Modern Cell Theory other special parts)
 developed in the 1830s by Matthias  derived from the Greek word “eu”
Schleiden and Theodor Schwann (good) and “karyon” (kernel),
who created the first two statements translating to true or good nuclei
 the last statement was proposed by  sometimes have cell walls with
Robert Remak but was plagiarized simple chemical composition
by Rudolph Virchow  has a nucleus, larger ribosomes,
 states that: mitochondria, linear DNA
arrangement, endoplasmic
1. All living things are composed of one reticulum, cell organelles,
or more cells. lysosomes, centrosomes, and larger
2. The cell is the basic unit of life. flagella
3. All cells are created by other cells. *  goes through mitosis for cell division
(not entirely factual since the first  reproduces through asexual and
cell may be produced from sexual processes
phospholipids that were able to form  includes plant and animal cells
bi-layers that act as membranes)

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Animal Cells differ from Plant cells since
they contain lysosomes and centrosomes.
Moreover, only plant cells possess
chloroplasts, other special plastids, and a
large central vacuole.

Prokaryotic Cells
 do not have a nucleus, mitochondria,
endoplasmic reticulum, nor
membrane-enclosed organelles
 have genetic material that is not
contained in a nucleus (nucleoid
region)
 always unicellular
 examples include bacteria
 derived from the Greek word “pro” Plasma Membrane
(before) and “karyon” (kernel) which  also known as the cell membrane
translates to before nuclei  always present in living cells found
 one of the most ancient groups of in multicellular organisms
living organisms on Earth  semi-permeable membrane that
 comparatively smaller and simpler separates the inner contents of the
compared to eukaryotes cell from its exterior environment
 usually have cell walls, circular DNA  described as a phospholipid layer
arrangement, smaller and spherical with embedded proteins that control
ribosomes, plasmids, and smaller the passage of organic molecules,
flagella ions, water, and oxygen into and out
 performs cell division through binary of the cell
fission or conjugation  wastes pass through this part to
 reproduces asexually escape the cell

Cell Wall
 a rigid structure present outside of a
STRUCTURE OF A EUKARYOTIC CELL plant cell
 absent in animal cells
 provides shape to cell and helps in
cell-to-cell interactions
 protective layer that keeps the cell
safe from any injury or pathogen
attacks
 composed of cellulose,
hemicellulose, pectin, proteins, etc.
 divided into three layers: the middle
lamella, primary wall, and secondary
wall

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 gel-like substance part of the
Cytoskeleton nucleus that stores chromatin
 a filamentous network present in the
cytoplasm of a cell Chromatin
 provides mechanical support  long strands of nucleic acids (DNA
 maintains the shape of the cell and RNA) and other proteins
 helps in motility (histones)
 describes the material that makes up
Endoplasmic Reticulum chromosomes
 network of small tubular structures  protein-chromosome complexes
 divides the space of eukaryotic cells (bead-like structure)
into two parts: luminal (inside the
ER) and extra-luminal (cytoplasm) Chromosomes
 divided into two types:  structures within the nucleus made
o Smooth ER – main site of up of DNA, the hereditary material
lipid synthesis and  linear structure in eukaryotes
characterized to be smooth  46 in human bodies
due to lack of ribosomes  Only visible and distinguishable
o Rough ER – site of protein when the cell is ready to divide
synthesis and rough due to
the presence of ribosomes;
helps in folding proteins
and transporting it to the Deoxyribonucleic Acid (DNA)
Golgi apparatus in vesicles  the instruction manual or blueprint of
the cell
 stores the generic information of the
Nucleus cell
 the command-and-control center of
the cell Histones
 house the cell’s DNA, and direct  material where DNA is wrapped
synthesis of ribosomes and proteins around to form a structure
 stores genetic information necessary resembling beads glued on a string
for development and reproduction
Nucleolus
Nuclear Envelope  condensed region of chromatins
 double-membrane structure that where ribosome synthesis occurs
surrounds the nucleus
 the outer membrane is continuous Ribosomes
with the nucleus while the inner  large complexes of protein and
membrane has small “nuclear pores” ribonucleic acids (RNA)
that allow substances to enter or exit  cellular organelles responsible for
the nucleus protein synthesis

Nucleoplasm

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 receive orders from the nucleus
where the DNA is transcribed into
messenger RNA (mRNA)
 mRNA travels to the ribosomes
which translates the code provided
by the sequence of nitrogenous
bases in the mRNA into a specific
order of amino acids in a protein
 made up of a large and small
subunit

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